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Targeting the transferrin receptor for brain drug delivery.

Johnsen KB, Burkhart A, Thomsen LB, Andresen TL, Moos T.

Prog Neurobiol. 2019 Oct;181:101665. doi: 10.1016/j.pneurobio.2019.101665. Epub 2019 Jul 31. Review.


Systematic review of targeted extracellular vesicles for drug delivery - Considerations on methodological and biological heterogeneity.

Gudbergsson JM, Jønsson K, Simonsen JB, Johnsen KB.

J Control Release. 2019 Jul 28;306:108-120. doi: 10.1016/j.jconrel.2019.06.006. Epub 2019 Jun 5. Review.


Exosomes and autophagy: rekindling the vesicular waste hypothesis.

Gudbergsson JM, Johnsen KB.

J Cell Commun Signal. 2019 Jun 6. doi: 10.1007/s12079-019-00524-8. [Epub ahead of print] Review.


A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response.

Gudbergsson JM, Kostrikov S, Johnsen KB, Fliedner FP, Stolberg CB, Humle N, Hansen AE, Kristensen BW, Christiansen G, Kjær A, Andresen TL, Duroux M.

Exp Cell Res. 2019 Jun 1;379(1):73-82. doi: 10.1016/j.yexcr.2019.03.031. Epub 2019 Mar 25.


DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain.

Pascal MMV, Themistocleous AC, Baron R, Binder A, Bouhassira D, Crombez G, Finnerup NB, Gierthmühlen J, Granovsky Y, Groop L, Hebert HL, Jensen TS, Johnsen K, McCarthy MI, Meng W, Palmer CNA, Rice ASC, Serra J, Solà R, Yarnitsky D, Smith BH, Attal N, Bennett DLH.

Version 2. Wellcome Open Res. 2019 Feb 1 [revised 2019 Jan 1];3:63. doi: 10.12688/wellcomeopenres.14576.2. eCollection 2018.


Phase- and season-dependent changes in social behaviour in cyclic vole populations.

Johnsen K, Devineau O, Andreassen HP.

BMC Ecol. 2019 Jan 25;19(1):5. doi: 10.1186/s12898-019-0222-3.


Points-Based Reward Systems in Gamification Impact Children's Physical Activity Strategies and Psychological Needs.

Ahn SJG, Johnsen K, Ball C.

Health Educ Behav. 2019 Jun;46(3):417-425. doi: 10.1177/1090198118818241. Epub 2019 Jan 24.


Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo.

Johnsen KB, Bak M, Melander F, Thomsen MS, Burkhart A, Kempen PJ, Andresen TL, Moos T.

J Control Release. 2019 Feb 10;295:237-249. doi: 10.1016/j.jconrel.2019.01.005. Epub 2019 Jan 10.


What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer.

Johnsen KB, Gudbergsson JM, Andresen TL, Simonsen JB.

Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):109-116. doi: 10.1016/j.bbcan.2018.11.006. Epub 2018 Dec 7. Review.


EEG may serve as a biomarker in Huntington's disease using machine learning automatic classification.

Odish OFF, Johnsen K, van Someren P, Roos RAC, van Dijk JG.

Sci Rep. 2018 Oct 31;8(1):16090. doi: 10.1038/s41598-018-34269-y.


Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.

Johnsen KB, Bak M, Kempen PJ, Melander F, Burkhart A, Thomsen MS, Nielsen MS, Moos T, Andresen TL.

Theranostics. 2018 May 24;8(12):3416-3436. doi: 10.7150/thno.25228. eCollection 2018.


On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems - A commentary.

Johnsen KB, Gudbergsson JM, Duroux M, Moos T, Andresen TL, Simonsen JB.

J Control Release. 2018 Jan 10;269:10-14. doi: 10.1016/j.jconrel.2017.11.002. Epub 2017 Nov 7. Review.


Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma.

Johnsen KB, Burkhart A, Melander F, Kempen PJ, Vejlebo JB, Siupka P, Nielsen MS, Andresen TL, Moos T.

Sci Rep. 2017 Sep 4;7(1):10396. doi: 10.1038/s41598-017-11220-1.


Surgical resection versus watchful waiting in low-grade gliomas.

Jakola AS, Skjulsvik AJ, Myrmel KS, Sjåvik K, Unsgård G, Torp SH, Aaberg K, Berg T, Dai HY, Johnsen K, Kloster R, Solheim O.

Ann Oncol. 2017 Aug 1;28(8):1942-1948. doi: 10.1093/annonc/mdx230.


Dynamics of soil CO2 efflux under varying atmospheric CO2 concentrations reveal dominance of slow processes.

Kim D, Oren R, Clark JS, Palmroth S, Oishi AC, McCarthy HR, Maier CA, Johnsen K.

Glob Chang Biol. 2017 Sep;23(9):3501-3512. doi: 10.1111/gcb.13713. Epub 2017 May 10.


Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.

Siupka P, Hersom MN, Lykke-Hartmann K, Johnsen KB, Thomsen LB, Andresen TL, Moos T, Abbott NJ, Brodin B, Nielsen MS.

J Cereb Blood Flow Metab. 2017 Jul;37(7):2598-2613. doi: 10.1177/0271678X17700665. Epub 2017 Mar 24.


Surviving winter: Food, but not habitat structure, prevents crashes in cyclic vole populations.

Johnsen K, Boonstra R, Boutin S, Devineau O, Krebs CJ, Andreassen HP.

Ecol Evol. 2016 Dec 14;7(1):115-124. doi: 10.1002/ece3.2635. eCollection 2017 Jan.


Ecosystem carbon density and allocation across a chronosequence of longleaf pine forests.

Samuelson LJ, Stokes TA, Butnor JR, Johnsen KH, Gonzalez-Benecke CA, Martin TA, Cropper WP Jr, Anderson PH, Ramirez MR, Lewis JC.

Ecol Appl. 2017 Jan;27(1):244-259. doi: 10.1002/eap.1439.


Repeated intensified infliximab induction - results from an 11-year prospective study of ulcerative colitis using a novel treatment algorithm.

Johnsen KM, Goll R, Hansen V, Olsen T, Rismo R, Heitmann R, Gundersen MD, Kvamme JM, Paulssen EJ, Kileng H, Johnsen K, Florholmen J.

Eur J Gastroenterol Hepatol. 2017 Jan;29(1):98-104.


Targeted Vascular Drug Delivery in Cerebral Cancer.

Humle N, Johnsen KB, Arendt GA, Nielsen RP, Moos T, Thomsen LB.

Curr Pharm Des. 2016;22(35):5487-5504. Review.


On the prospect of clinical utilization of microRNAs as biomarkers or treatment of chronic pain.

Andersen HH, Johnsen KB, Arendt-Nielsen L.

Exp Neurol. 2016 Oct;284(Pt A):63-66. doi: 10.1016/j.expneurol.2016.07.008. Epub 2016 Jul 18. No abstract available.


Multimodal EEG-MRI in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies.

Colloby SJ, Cromarty RA, Peraza LR, Johnsen K, Jóhannesson G, Bonanni L, Onofrj M, Barber R, O'Brien JT, Taylor JP.

J Psychiatr Res. 2016 Jul;78:48-55. doi: 10.1016/j.jpsychires.2016.03.010. Epub 2016 Mar 25.


Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes.

Johnsen KB, Gudbergsson JM, Skov MN, Christiansen G, Gurevich L, Moos T, Duroux M.

Cytotechnology. 2016 Oct;68(5):2125-38. doi: 10.1007/s10616-016-9952-7. Epub 2016 Feb 8.


Normalization of mucosal tumor necrosis factor-α: A new criterion for discontinuing infliximab therapy in ulcerative colitis.

Olsen T, Rismo R, Gundersen MD, Paulssen EJ, Johnsen K, Kvamme JM, Goll R, Florholmen J.

Cytokine. 2016 Mar;79:90-5. doi: 10.1016/j.cyto.2015.12.021. Epub 2016 Jan 8.


Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier.

Burkhart A, Skjørringe T, Johnsen KB, Siupka P, Thomsen LB, Nielsen MS, Thomsen LL, Moos T.

Mol Neurobiol. 2016 Dec;53(10):7237-7253. Epub 2015 Dec 21.


Revisiting nanoparticle technology for blood-brain barrier transport: Unfolding at the endothelial gate improves the fate of transferrin receptor-targeted liposomes.

Johnsen KB, Moos T.

J Control Release. 2016 Jan 28;222:32-46. doi: 10.1016/j.jconrel.2015.11.032. Epub 2015 Dec 3. Review.


Development and Use of an Interactive Computerized Dog Model to Evaluate Cranial Nerve Knowledge in Veterinary Students.

Bogert K, Platt S, Haley A, Kent M, Edwards G, Dookwah H, Johnsen K.

J Vet Med Educ. 2016 Spring;43(1):26-32. doi: 10.3138/jvme.0215-027R1. Epub 2015 Nov 11.


Using Virtual Pets to Increase Fruit and Vegetable Consumption in Children: A Technology-Assisted Social Cognitive Theory Approach.

Ahn SJ, Johnsen K, Moore J, Brown S, Biersmith M, Ball C.

Cyberpsychol Behav Soc Netw. 2016 Feb;19(2):86-92. doi: 10.1089/cyber.2015.0224. Epub 2015 Oct 15.


Systematic review of factors influencing extracellular vesicle yield from cell cultures.

Gudbergsson JM, Johnsen KB, Skov MN, Duroux M.

Cytotechnology. 2016 Aug;68(4):579-92. doi: 10.1007/s10616-015-9913-6. Epub 2015 Oct 3. Review.


Can sleep quality and wellbeing be improved by changing the indoor lighting in the homes of healthy, elderly citizens?

Sander B, Markvart J, Kessel L, Argyraki A, Johnsen K.

Chronobiol Int. 2015;32(8):1049-60. doi: 10.3109/07420528.2015.1056304.


Divalent metal transporter 1 (DMT1) in the brain: implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology.

Skjørringe T, Burkhart A, Johnsen KB, Moos T.

Front Mol Neurosci. 2015 Jun 8;8:19. doi: 10.3389/fnmol.2015.00019. eCollection 2015. Review.


Using Virtual Pets to Promote Physical Activity in Children: An Application of the Youth Physical Activity Promotion Model.

Ahn SJ, Johnsen K, Robertson T, Moore J, Brown S, Marable A, Basu A.

J Health Commun. 2015;20(7):807-15. doi: 10.1080/10810730.2015.1018597. Epub 2015 May 28.


A recent bottleneck of Y chromosome diversity coincides with a global change in culture.

Karmin M, Saag L, Vicente M, Wilson Sayres MA, Järve M, Talas UG, Rootsi S, Ilumäe AM, Mägi R, Mitt M, Pagani L, Puurand T, Faltyskova Z, Clemente F, Cardona A, Metspalu E, Sahakyan H, Yunusbayev B, Hudjashov G, DeGiorgio M, Loogväli EL, Eichstaedt C, Eelmets M, Chaubey G, Tambets K, Litvinov S, Mormina M, Xue Y, Ayub Q, Zoraqi G, Korneliussen TS, Akhatova F, Lachance J, Tishkoff S, Momynaliev K, Ricaut FX, Kusuma P, Razafindrazaka H, Pierron D, Cox MP, Sultana GN, Willerslev R, Muller C, Westaway M, Lambert D, Skaro V, Kovačevic L, Turdikulova S, Dalimova D, Khusainova R, Trofimova N, Akhmetova V, Khidiyatova I, Lichman DV, Isakova J, Pocheshkhova E, Sabitov Z, Barashkov NA, Nymadawa P, Mihailov E, Seng JW, Evseeva I, Migliano AB, Abdullah S, Andriadze G, Primorac D, Atramentova L, Utevska O, Yepiskoposyan L, Marjanovic D, Kushniarevich A, Behar DM, Gilissen C, Vissers L, Veltman JA, Balanovska E, Derenko M, Malyarchuk B, Metspalu A, Fedorova S, Eriksson A, Manica A, Mendez FL, Karafet TM, Veeramah KR, Bradman N, Hammer MF, Osipova LP, Balanovsky O, Khusnutdinova EK, Johnsen K, Remm M, Thomas MG, Tyler-Smith C, Underhill PA, Willerslev E, Nielsen R, Metspalu M, Villems R, Kivisild T.

Genome Res. 2015 Apr;25(4):459-66. doi: 10.1101/gr.186684.114. Epub 2015 Mar 13.


Prevalence of self-reported stomach symptoms after consuming milk among indigenous Sami and non-Sami in Northern- and Mid-Norway - the SAMINOR study.

Hansen KL, Brustad M, Johnsen K.

Int J Circumpolar Health. 2015 Feb 17;74:25762. doi: 10.3402/ijch.v74.25762. eCollection 2015.


Electroencephalography as a clinical tool for diagnosing and monitoring attention deficit hyperactivity disorder: a cross-sectional study.

Helgadóttir H, Gudmundsson ÓÓ, Baldursson G, Magnússon P, Blin N, Brynjólfsdóttir B, Emilsdóttir Á, Gudmundsdóttir GB, Lorange M, Newman PK, Jóhannesson GH, Johnsen K.

BMJ Open. 2015 Jan 16;5(1):e005500. doi: 10.1136/bmjopen-2014-005500.


Prevalence of self-reported stomach symptoms after consuming milk among indigenous Sami and non-Sami in Northern- and Mid-Norway - the SAMINOR study.

Hansen KL, Brustad M, Johnsen K.

Int J Circumpolar Health. 2015 Jan;74(1):25762. doi: 10.3402/ijch.v74.25762.


The acetylcholine index: an electroencephalographic marker of cholinergic activity in the living human brain applied to Alzheimer's disease and other dementias.

Johannsson M, Snaedal J, Johannesson GH, Gudmundsson TE, Johnsen K.

Dement Geriatr Cogn Disord. 2015;39(3-4):132-42. doi: 10.1159/000367889. Epub 2014 Nov 27.


If you want to be good, start early.

Okkels N, Vig Benfeldt F, Johnsen K, Le M.

Acta Psychiatr Scand. 2014 Oct;130(4):318. doi: 10.1111/acps.12311. Epub 2014 Jul 10. No abstract available.


MicroRNA expression signatures and their correlation with clinicopathological features in glioblastoma multiforme.

Henriksen M, Johnsen KB, Olesen P, Pilgaard L, Duroux M.

Neuromolecular Med. 2014 Sep;16(3):565-77. doi: 10.1007/s12017-014-8309-7. Epub 2014 May 10.


Time-resolved double-slit interference pattern measurement with entangled photons.

Kolenderski P, Scarcella C, Johnsen KD, Hamel DR, Holloway C, Shalm LK, Tisa S, Tosi A, Resch KJ, Jennewein T.

Sci Rep. 2014 Apr 28;4:4685. doi: 10.1038/srep04685.


A comprehensive overview of exosomes as drug delivery vehicles - endogenous nanocarriers for targeted cancer therapy.

Johnsen KB, Gudbergsson JM, Skov MN, Pilgaard L, Moos T, Duroux M.

Biochim Biophys Acta. 2014 Aug;1846(1):75-87. doi: 10.1016/j.bbcan.2014.04.005. Epub 2014 Apr 18. Review.


Virtual patient simulations and optimal social learning context: a replication of an aptitude-treatment interaction effect.

Johnson TR, Lyons R, Kopper R, Johnsen KJ, Lok BC, Cendan JC.

Med Teach. 2014 Jun;36(6):486-94. doi: 10.3109/0142159X.2014.890702. Epub 2014 Apr 16.


Mixed reality virtual pets to reduce childhood obesity.

Johnsen K, Ahn SJ, Moore J, Brown S, Robertson TP, Marable A, Basu A.

IEEE Trans Vis Comput Graph. 2014 Apr;20(4):523-30. doi: 10.1109/TVCG.2014.33.


MicroRNA expression signatures determine prognosis and survival in glioblastoma multiforme--a systematic overview.

Henriksen M, Johnsen KB, Andersen HH, Pilgaard L, Duroux M.

Mol Neurobiol. 2014 Dec;50(3):896-913. doi: 10.1007/s12035-014-8668-y. Epub 2014 Mar 12. Review.


Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration.

Andersen HH, Johnsen KB, Moos T.

Cell Mol Life Sci. 2014 May;71(9):1607-22. doi: 10.1007/s00018-013-1509-8. Epub 2013 Nov 12. Review.


Sustained effects of atmospheric [CO2] and nitrogen availability on forest soil CO2 efflux.

Oishi AC, Palmroth S, Johnsen KH, McCarthy HR, Oren R.

Glob Chang Biol. 2014 Apr;20(4):1146-60. doi: 10.1111/gcb.12414. Epub 2014 Feb 12.


Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease.

Rismo R, Olsen T, Cui G, Paulssen EJ, Christiansen I, Johnsen K, Florholmen J, Goll R.

Scand J Gastroenterol. 2013 Mar;48(3):311-9. doi: 10.3109/00365521.2012.758773. Epub 2013 Jan 10.


A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion.

Møller HG, Rasmussen AP, Andersen HH, Johnsen KB, Henriksen M, Duroux M.

Mol Neurobiol. 2013 Feb;47(1):131-44. doi: 10.1007/s12035-012-8349-7. Epub 2012 Oct 2. Review.


Diagnostic accuracy of statistical pattern recognition of electroencephalogram registration in evaluation of cognitive impairment and dementia.

Snaedal J, Johannesson GH, Gudmundsson TE, Blin NP, Emilsdottir AL, Einarsson B, Johnsen K.

Dement Geriatr Cogn Disord. 2012;34(1):51-60. doi: 10.1159/000339996. Epub 2012 Aug 23.


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