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Items: 1 to 50 of 52

1.

Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap.

Lee YA, Noon LA, Akat KM, Ybanez MD, Lee TF, Berres ML, Fujiwara N, Goossens N, Chou HI, Parvin-Nejad FP, Khambu B, Kramer EGM, Gordon R, Pfleger C, Germain D, John GR, Campbell KN, Yue Z, Yin XM, Cuervo AM, Czaja MJ, Fiel MI, Hoshida Y, Friedman SL.

Nat Commun. 2018 Nov 23;9(1):4962. doi: 10.1038/s41467-018-07338-z.

2.

Correction: Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (doi:10.1242/dev.106492).

Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR.

Development. 2018 Jul 13;145(13). pii: dev168708. doi: 10.1242/dev.168708. No abstract available.

3.

Astrocytic tight junctions control inflammatory CNS lesion pathogenesis.

Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw AT, Hara Y, Mariani JN, Sawai S, Flodby P, Crandall ED, Borok Z, Sofroniew MV, Chapouly C, John GR.

J Clin Invest. 2017 Aug 1;127(8):3136-3151. doi: 10.1172/JCI91301. Epub 2017 Jul 24.

4.

Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.

Laitman BM, Mariani JN, Zhang C, Sawai S, John GR.

PLoS One. 2017 Jan 20;12(1):e0170477. doi: 10.1371/journal.pone.0170477. eCollection 2017.

5.

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination.

Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR.

PLoS Biol. 2016 May 23;14(5):e1002467. doi: 10.1371/journal.pbio.1002467. eCollection 2016 May.

6.

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.

Moyon S, Huynh JL, Dutta D, Zhang F, Ma D, Yoo S, Lawrence R, Wegner M, John GR, Emery B, Lubetzki C, Franklin RJM, Fan G, Zhu J, Dupree JL, Casaccia P.

Cell Rep. 2016 Apr 26;15(4):748-760. doi: 10.1016/j.celrep.2016.03.060. Epub 2016 Apr 14.

7.

Relapses in multiple sclerosis: Relationship to disability.

Goodin DS, Reder AT, Bermel RA, Cutter GR, Fox RJ, John GR, Lublin FD, Lucchinetti CF, Miller AE, Pelletier D, Racke MK, Trapp BD, Vartanian T, Waubant E.

Mult Scler Relat Disord. 2016 Mar;6:10-20. doi: 10.1016/j.msard.2015.09.002. Epub 2015 Sep 8. Review.

PMID:
27063617
8.

Understanding How Exercise Promotes Cognitive Integrity in the Aging Brain.

Laitman BM, John GR.

PLoS Biol. 2015 Nov 11;13(11):e1002300. doi: 10.1371/journal.pbio.1002300. eCollection 2015.

9.

Update on biomarkers in neuromyelitis optica.

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S.

Neurol Neuroimmunol Neuroinflamm. 2015 Jul 23;2(4):e134. doi: 10.1212/NXI.0000000000000134. eCollection 2015 Aug. Review.

10.

Astrocytic TYMP and VEGFA drive blood-brain barrier opening in inflammatory central nervous system lesions.

Chapouly C, Tadesse Argaw A, Horng S, Castro K, Zhang J, Asp L, Loo H, Laitman BM, Mariani JN, Straus Farber R, Zaslavsky E, Nudelman G, Raine CS, John GR.

Brain. 2015 Jun;138(Pt 6):1548-67. doi: 10.1093/brain/awv077. Epub 2015 Mar 23.

11.

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.

Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR.

Development. 2014 Jun;141(12):2414-28. doi: 10.1242/dev.106492. Erratum in: Development. 2018 Jul 13;145(13):.

12.

Accelerated repair of demyelinated CNS lesions in the absence of non-muscle myosin IIB.

Rusielewicz T, Nam J, Damanakis E, John GR, Raine CS, Melendez-Vasquez CV.

Glia. 2014 Apr;62(4):580-91. doi: 10.1002/glia.22627. Epub 2014 Jan 28.

13.

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination.

Brück W, Pförtner R, Pham T, Zhang J, Hayardeny L, Piryatinsky V, Hanisch UK, Regen T, van Rossum D, Brakelmann L, Hagemeier K, Kuhlmann T, Stadelmann C, John GR, Kramann N, Wegner C.

Acta Neuropathol. 2012 Sep;124(3):411-24. doi: 10.1007/s00401-012-1009-1. Epub 2012 Jul 6.

14.

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease.

Argaw AT, Asp L, Zhang J, Navrazhina K, Pham T, Mariani JN, Mahase S, Dutta DJ, Seto J, Kramer EG, Ferrara N, Sofroniew MV, John GR.

J Clin Invest. 2012 Jul;122(7):2454-68. doi: 10.1172/JCI60842. Epub 2012 Jun 1.

15.

Investigation of astrocyte - oligodendrocyte interactions in human cultures.

John GR.

Methods Mol Biol. 2012;814:401-14. doi: 10.1007/978-1-61779-452-0_27.

16.

On the occurrence of hypomyelination in a transgenic mouse model: a consequence of the myelin basic protein promoter?

Gaupp S, Arezzo J, Dutta DJ, John GR, Raine CS.

J Neuropathol Exp Neurol. 2011 Dec;70(12):1138-50. doi: 10.1097/NEN.0b013e31823b188b.

17.

Promoting myelin repair and return of function in multiple sclerosis.

Zhang J, Kramer EG, Asp L, Dutta DJ, Navrazhina K, Pham T, Mariani JN, Argaw AT, Melendez-Vasquez CV, John GR.

FEBS Lett. 2011 Dec 1;585(23):3813-20. doi: 10.1016/j.febslet.2011.08.017. Epub 2011 Aug 18. Review.

18.

Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11.

Zhang J, Zhang Y, Dutta DJ, Argaw AT, Bonnamain V, Seto J, Braun DA, Zameer A, Hayot F, Lòpez CB, Raine CS, John GR.

J Immunol. 2011 Aug 1;187(3):1129-41. doi: 10.4049/jimmunol.1004066. Epub 2011 Jun 27.

19.

Targeting oligodendrocyte protection and remyelination in multiple sclerosis.

Zhang J, Kramer EG, Mahase S, Dutta DJ, Bonnamain V, Argaw AT, John GR.

Mt Sinai J Med. 2011 Mar-Apr;78(2):244-57. doi: 10.1002/msj.20244. Review.

20.

Glatiramer acetate-reactive T lymphocytes regulate oligodendrocyte progenitor cell number in vitro: role of IGF-2.

Zhang Y, Jalili F, Ouamara N, Zameer A, Cosentino G, Mayne M, Hayardeny L, Antel JP, Bar-Or A, John GR.

J Neuroimmunol. 2010 Oct 8;227(1-2):71-9. doi: 10.1016/j.jneuroim.2010.06.014. Epub 2010 Jul 15.

21.

TGFbeta1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation.

Zhang Y, Zhang J, Navrazhina K, Argaw AT, Zameer A, Gurfein BT, Brosnan CF, John GR.

Glia. 2010 Jun;58(8):964-74. doi: 10.1002/glia.20978.

22.

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, Lu QR, Rowitch DH, Raine CS, Brosnan CF, John GR.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19162-7. doi: 10.1073/pnas.0902834106. Epub 2009 Oct 23.

23.

IL-11 regulates autoimmune demyelination.

Gurfein BT, Zhang Y, López CB, Argaw AT, Zameer A, Moran TM, John GR.

J Immunol. 2009 Oct 1;183(7):4229-40. doi: 10.4049/jimmunol.0900622. Epub 2009 Sep 4.

24.

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown.

Argaw AT, Gurfein BT, Zhang Y, Zameer A, John GR.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1977-82. doi: 10.1073/pnas.0808698106. Epub 2009 Jan 27.

25.

Revisiting Notch in remyelination of multiple sclerosis lesions.

Brosnan CF, John GR.

J Clin Invest. 2009 Jan;119(1):10-3. doi: 10.1172/JCI37786.

26.

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation.

Zhang Y, Taveggia C, Melendez-Vasquez C, Einheber S, Raine CS, Salzer JL, Brosnan CF, John GR.

J Neurosci. 2006 Nov 22;26(47):12174-85.

27.

IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program.

Argaw AT, Zhang Y, Snyder BJ, Zhao ML, Kopp N, Lee SC, Raine CS, Brosnan CF, John GR.

J Immunol. 2006 Oct 15;177(8):5574-84.

28.

CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis.

Omari KM, John GR, Sealfon SC, Raine CS.

Brain. 2005 May;128(Pt 5):1003-15. Epub 2005 Mar 17.

PMID:
15774504
29.

The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture.

Rivieccio MA, John GR, Song X, Suh HS, Zhao Y, Lee SC, Brosnan CF.

J Immunol. 2005 Mar 15;174(6):3719-26.

30.

IL-1-regulated responses in astrocytes: relevance to injury and recovery.

John GR, Lee SC, Song X, Rivieccio M, Brosnan CF.

Glia. 2005 Jan 15;49(2):161-76. Review.

PMID:
15472994
31.

Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.

John GR, Chen L, Rivieccio MA, Melendez-Vasquez CV, Hartley A, Brosnan CF.

J Neurosci. 2004 Mar 17;24(11):2837-45.

32.

Cytokines: powerful regulators of glial cell activation.

John GR, Lee SC, Brosnan CF.

Neuroscientist. 2003 Feb;9(1):10-22. Review.

PMID:
12580336
33.

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation.

John GR, Shankar SL, Shafit-Zagardo B, Massimi A, Lee SC, Raine CS, Brosnan CF.

Nat Med. 2002 Oct;8(10):1115-21. Epub 2002 Sep 23.

PMID:
12357247
34.
35.
36.
37.

Effects of 4-aminopyridine on demyelinated axons, synapses and muscle tension.

Smith KJ, Felts PA, John GR.

Brain. 2000 Jan;123 ( Pt 1):171-84.

PMID:
10611131
38.

IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels.

John GR, Scemes E, Suadicani SO, Liu JS, Charles PC, Lee SC, Spray DC, Brosnan CF.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11613-8.

40.
41.

Airbag-associated ocular injury and periorbital fractures.

Scott IU, John GR, Stark WJ.

Arch Ophthalmol. 1993 Jan;111(1):25. No abstract available.

PMID:
8280191
42.
43.

Periorbital urticarial drug reaction associated with intravenously administered methylprednisolone.

John GR, Stark WJ.

Am J Ophthalmol. 1992 May 15;113(5):588-90. No abstract available.

PMID:
1575238
44.

Eye injury: prevalence and prognosis by setting.

White MF Jr, Morris R, Feist RM, Witherspoon CD, Helms HA Jr, John GR.

South Med J. 1989 Feb;82(2):151-8.

PMID:
2916138
45.
46.
47.

Alterations in phospholipid methylation in rat brain synaptosomal membranes produced by ethanol in vitro and in vivo.

Nhamburo PT, John GR, Littleton JM.

Biochem Pharmacol. 1982 Dec 1;31(23):3936-8. No abstract available.

PMID:
6891589
48.

Membrane lipids and ethanol tolerance in the mouse. The influence of dietary fatty acid composition.

John GR, Littleton JM, Jones PA.

Life Sci. 1980 Aug 18;27(7):545-55. No abstract available.

PMID:
7421411
49.

Ethanol-induced alteration in membrane phospholipid composition : possible relationship to development of cellular tolerance to ethanol.

Littleton JM, Grieve SJ, Griffiths PJ, John GR.

Adv Exp Med Biol. 1980;126:7-19. No abstract available.

PMID:
7405706
50.

The rapid onset of functional tolerance to ethanol--role of different neurotransmitters and synaptosomal membrane lipids.

Littleton JM, John GR, Jones PA, Grieve SJ.

Acta Psychiatr Scand Suppl. 1980;286:137-51.

PMID:
6109429

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