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Items: 1 to 50 of 209

1.

Evolutionary highways to persistent bacterial infection.

Bartell JA, Sommer LM, Haagensen JAJ, Loch A, Espinosa R, Molin S, Johansen HK.

Nat Commun. 2019 Feb 7;10(1):629. doi: 10.1038/s41467-019-08504-7.

2.

Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study.

Alanin MC, Pressler T, Aanaes K, Ekstrøm CT, Skov M, Johansen HK, Nielsen KG, von Buchwald C, Høiby N.

Health Sci Rep. 2018 Jul 12;1(8):e52. doi: 10.1002/hsr2.52. eCollection 2018 Aug.

3.

Privatisation rescues function following loss of cooperation.

Andersen SB, Ghoul M, Marvig RL, Lee ZB, Molin S, Johansen HK, Griffin AS.

Elife. 2018 Dec 18;7. pii: e38594. doi: 10.7554/eLife.38594.

4.

Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment.

Lausch KR, Søgaard M, Rosenvinge FS, Johansen HK, Boysen T, Røder BL, Mortensen KL, Nielsen L, Lemming L, Olesen B, Leitz C, Kristensen L, Dzajic E, Østergaard LJ, Schønheyder HC, Arendrup MC.

Infect Drug Resist. 2018 Nov 23;11:2449-2459. doi: 10.2147/IDR.S176384. eCollection 2018.

5.

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.

Scott WK, Medie FM, Ruffin F, Sharma-Kuinkel BK, Cyr DD, Guo S, Dykxhoorn DM, Skov RL, Bruun NE, Dahl A, Lerche CJ, Petersen A, Larsen AR, Lauridsen TK, Johansen HK, Ullum H, Sørensen E, Hassager C, Bundgaard H, Schønheyder HC, Torp-Pedersen C, Østergaard LB, Arpi M, Rosenvinge F, Erikstrup LT, Chehri M, Søgaard P, Andersen PS, Fowler VG Jr.

PLoS Genet. 2018 Oct 5;14(10):e1007667. doi: 10.1371/journal.pgen.1007667. eCollection 2018 Oct.

6.

Defining antimicrobial resistance in cystic fibrosis.

Kidd TJ, Canton R, Ekkelenkamp M, Johansen HK, Gilligan P, LiPuma JJ, Bell SC, Elborn JS, Flume PA, VanDevanter DR, Waters VJ; Antimicrobial Resistance in Cystic Fibrosis International Working Group.

J Cyst Fibros. 2018 Nov;17(6):696-704. doi: 10.1016/j.jcf.2018.08.014. Epub 2018 Sep 25. Review.

PMID:
30266518
7.

High incidence of candidaemia in a nationwide cohort: Underlying diseases, risk factors and mortality.

Lausch KR, Søgaard M, Rosenvinge FS, Johansen HK, Boysen T, Røder B, Mortensen KL, Nielsen L, Lemming L, Olesen B, Leitz C, Kristensen L, Dzajic E, Østergaard L, Schønheyder HC, Arendrup MC.

Int J Infect Dis. 2018 Nov;76:58-63. doi: 10.1016/j.ijid.2018.08.010. Epub 2018 Aug 31.

8.

High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs.

Rossi E, Falcone M, Molin S, Johansen HK.

Nat Commun. 2018 Aug 27;9(1):3459. doi: 10.1038/s41467-018-05944-5.

9.

Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts.

Frimodt-Møller J, Rossi E, Haagensen JAJ, Falcone M, Molin S, Johansen HK.

Sci Rep. 2018 Aug 21;8(1):12512. doi: 10.1038/s41598-018-30972-y.

10.

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa.

La Rosa R, Johansen HK, Molin S.

MBio. 2018 Apr 10;9(2). pii: e00269-18. doi: 10.1128/mBio.00269-18.

11.

Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa.

Alatraktchi FA, Noori JS, Tanev GP, Mortensen J, Dimaki M, Johansen HK, Madsen J, Molin S, Svendsen WE.

PLoS One. 2018 Mar 22;13(3):e0194157. doi: 10.1371/journal.pone.0194157. eCollection 2018.

12.

The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy.

Aanaes K, Alanin MC, Nielsen KG, Moller Jorgensen M, von Buchwald C, Hoiby N, Johansen HK, Johannesen HH, Mortensen J.

Rhinology. 2018 Sep 1;56(3):268-273. doi: 10.4193/Rhin17.243.

PMID:
29509830
13.

The Small RNA ErsA of Pseudomonas aeruginosa Contributes to Biofilm Development and Motility through Post-transcriptional Modulation of AmrZ.

Falcone M, Ferrara S, Rossi E, Johansen HK, Molin S, Bertoni G.

Front Microbiol. 2018 Feb 15;9:238. doi: 10.3389/fmicb.2018.00238. eCollection 2018.

14.

Update from a 12-Year Nationwide Fungemia Surveillance: Increasing Intrinsic and Acquired Resistance Causes Concern.

Astvad KMT, Johansen HK, Røder BL, Rosenvinge FS, Knudsen JD, Lemming L, Schønheyder HC, Hare RK, Kristensen L, Nielsen L, Gertsen JB, Dzajic E, Pedersen M, Østergård C, Olesen B, Søndergaard TS, Arendrup MC.

J Clin Microbiol. 2018 Mar 26;56(4). pii: e01564-17. doi: 10.1128/JCM.01564-17. Print 2018 Apr.

15.

Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis.

Lilje B, Rasmussen RV, Dahl A, Stegger M, Skov RL, Fowler VG, Ng KL, Kiil K, Larsen AR, Petersen A, Johansen HK, Schønheyder HC, Arpi M, Rosenvinge FS, Korup E, Høst U, Hassager C, Gill SUA, Hansen TF, Johannesen TB, Smit J, Søgaard P, Skytt Andersen P, Eske-Bruun N.

Microb Genom. 2017 Nov;3(11). doi: 10.1099/mgen.0.000138.

16.

Clinical care of children with primary ciliary dyskinesia.

Lucas JS, Alanin MC, Collins S, Harris A, Johansen HK, Nielsen KG, Papon JF, Robinson P, Walker WT.

Expert Rev Respir Med. 2017 Oct;11(10):779-790. doi: 10.1080/17476348.2017.1360770. Epub 2017 Aug 2. Review.

PMID:
28745925
17.

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.

López-Causapé C, Sommer LM, Cabot G, Rubio R, Ocampo-Sosa AA, Johansen HK, Figuerola J, Cantón R, Kidd TJ, Molin S, Oliver A.

Sci Rep. 2017 Jul 17;7(1):5555. doi: 10.1038/s41598-017-05621-5.

18.

Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs.

Andersen SB, Ghoul M, Griffin AS, Petersen B, Johansen HK, Molin S.

Front Microbiol. 2017 Jun 23;8:1180. doi: 10.3389/fmicb.2017.01180. eCollection 2017.

19.

Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

Jensen RG, Johansen HK, Bjarnsholt T, Eickhardt-Sørensen SR, Homøe P.

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2741-2747. doi: 10.1007/s00405-017-4586-8. Epub 2017 May 2.

PMID:
28466356
20.

SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients.

Lauridsen RK, Sommer LM, Johansen HK, Rindzevicius T, Molin S, Jelsbak L, Engelsen SB, Boisen A.

Sci Rep. 2017 Mar 28;7:45264. doi: 10.1038/srep45264.

21.

Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients.

Schultz AN, Høiby N, Nielsen XC, Pressler T, Dalhoff K, Duno M, Buchard A, Johansen HK, Wang H, Dalbøge CS.

Pediatr Pulmonol. 2017 Mar;52(3):319-323. doi: 10.1002/ppul.23638. Epub 2016 Nov 4.

PMID:
28221736
22.

Is parotid saliva sterile on entry to the oral cavity?

Schrøder SA, Bardow A, Eickhardt-Dalbøge S, Johansen HK, Homøe P.

Acta Otolaryngol. 2017 Jul;137(7):762-764. doi: 10.1080/00016489.2016.1272002. Epub 2017 Jan 26.

PMID:
28125321
23.

Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats.

Søe NH, Jensen NV, Jensen AL, Koch J, Poulsen SS, Pier GB, Johansen HK.

In Vivo. 2017 Jan 2;31(1):45-50.

24.

Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia.

Alanin MC, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, Johansen HK, von Buchwald C.

Int Forum Allergy Rhinol. 2017 Mar;7(3):240-247. doi: 10.1002/alr.21873. Epub 2016 Nov 23.

PMID:
27879058
25.

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease.

Gøtzsche PC, Johansen HK.

Cochrane Database Syst Rev. 2016 Sep 20;9:CD007851. doi: 10.1002/14651858.CD007851.pub3. Review.

PMID:
27644166
26.

Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?

Sommer LM, Marvig RL, Luján A, Koza A, Pressler T, Molin S, Johansen HK.

BMC Genomics. 2016 Aug 9;17:589. doi: 10.1186/s12864-016-2873-1.

27.

Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections.

Alatraktchi FA, Johansen HK, Molin S, Svendsen WE.

Nanomedicine (Lond). 2016 Aug;11(16):2185-95. doi: 10.2217/nnm-2016-0155. Epub 2016 Jul 27.

28.

Bacterial evolution in PCD and CF patients follows the same mutational steps.

Sommer LM, Alanin MC, Marvig RL, Nielsen KG, Høiby N, von Buchwald C, Molin S, Johansen HK.

Sci Rep. 2016 Jun 28;6:28732. doi: 10.1038/srep28732.

29.

Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry.

Alatraktchi FA, Andersen SB, Johansen HK, Molin S, Svendsen WE.

Sensors (Basel). 2016 Mar 19;16(3). pii: E408. doi: 10.3390/s16030408.

30.

Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study.

Jensen RH, Johansen HK, Søes LM, Lemming LE, Rosenvinge FS, Nielsen L, Olesen B, Kristensen L, Dzajic E, Astvad KM, Arendrup MC.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1500-8. doi: 10.1128/AAC.01763-15.

31.

Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients.

Marvig RL, Dolce D, Sommer LM, Petersen B, Ciofu O, Campana S, Molin S, Taccetti G, Johansen HK.

BMC Microbiol. 2015 Oct 19;15:218. doi: 10.1186/s12866-015-0563-9.

32.

Pre-adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates.

Friman VP, Soanes-Brown D, Sierocinski P, Molin S, Johansen HK, Merabishvili M, Pirnay JP, De Vos D, Buckling A.

J Evol Biol. 2016 Jan;29(1):188-98. doi: 10.1111/jeb.12774. Epub 2015 Nov 9.

33.

A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia.

Alanin MC, Nielsen KG, von Buchwald C, Skov M, Aanaes K, Høiby N, Johansen HK.

Clin Microbiol Infect. 2015 Dec;21(12):1093.e1-7. doi: 10.1016/j.cmi.2015.08.020. Epub 2015 Sep 2.

34.

Bacteriocin-mediated competition in cystic fibrosis lung infections.

Ghoul M, West SA, Johansen HK, Molin S, Harrison OB, Maiden MC, Jelsbak L, Bruce JB, Griffin AS.

Proc Biol Sci. 2015 Sep 7;282(1814). doi: 10.1098/rspb.2015.0972.

35.

Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis.

Johansen HK, Gøtzsche PC.

Cochrane Database Syst Rev. 2015 Aug 23;(8):CD001399. doi: 10.1002/14651858.CD001399.pub4. Review.

PMID:
26298311
36.

Oropharyngeal Candidiasis in Palliative Care Patients in Denmark.

Astvad K, Johansen HK, Høiby N, Steptoe P, Ishøy T.

J Palliat Med. 2015 Nov;18(11):940-4. doi: 10.1089/jpm.2015.29003.ka. Epub 2015 Aug 13.

PMID:
26270132
37.

Antibiofilm Properties of Acetic Acid.

Bjarnsholt T, Alhede M, Jensen PØ, Nielsen AK, Johansen HK, Homøe P, Høiby N, Givskov M, Kirketerp-Møller K.

Adv Wound Care (New Rochelle). 2015 Jul 1;4(7):363-372.

38.

Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing.

Bartels MD, Larner-Svensson H, Meiniche H, Kristoffersen K, Schonning K, Nielsen JB, Rohde SM, Christensen LB, Skibsted AW, Jarlov JO, Johansen HK, Andersen LP, Petersen IS, Crook DW, Bowden R, Boye K, Worning P, Westh H.

Euro Surveill. 2015 Apr 30;20(17). pii: 21112.

39.

Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection.

Jørgensen KM, Wassermann T, Johansen HK, Christiansen LE, Molin S, Høiby N, Ciofu O.

Microbiology. 2015 Jul;161(7):1447-62. doi: 10.1099/mic.0.000093. Epub 2015 Apr 13.

PMID:
25873584
40.

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients.

Marvig RL, Sommer LM, Jelsbak L, Molin S, Johansen HK.

Future Microbiol. 2015;10(4):599-611. doi: 10.2217/fmb.15.3. Review.

PMID:
25865196
41.

The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study.

Skov M, Pressler T, Lykkesfeldt J, Poulsen HE, Jensen PØ, Johansen HK, Qvist T, Kræmer D, Høiby N, Ciofu O.

J Cyst Fibros. 2015 Mar;14(2):211-8. doi: 10.1016/j.jcf.2014.09.015. Epub 2014 Oct 23.

42.

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis.

Marvig RL, Sommer LM, Molin S, Johansen HK.

Nat Genet. 2015 Jan;47(1):57-64. doi: 10.1038/ng.3148. Epub 2014 Nov 17.

PMID:
25401299
43.

Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia.

Alanin MC, Johansen HK, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, von Buchwald C.

Acta Otolaryngol. 2015 Jan;135(1):58-63. doi: 10.3109/00016489.2014.962185. Epub 2014 Nov 5.

PMID:
25370419
44.

[Epiglottitis with an abscess caused by Haemophilus parainfluenzae].

Juul ML, Johansen HK, Homøe P.

Ugeskr Laeger. 2014 Mar 17;176(12A). pii: V11130683. Danish.

PMID:
25350891
45.

Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

Aanaes K, Eickhardt S, Johansen HK, von Buchwald C, Skov M, Høiby N, Bjarnsholt T.

Eur Arch Otorhinolaryngol. 2015 Sep;272(9):2291-7. doi: 10.1007/s00405-014-3322-x. Epub 2014 Oct 9.

PMID:
25297534
46.

Comparing whole-genome sequencing with Sanger sequencing for spa typing of methicillin-resistant Staphylococcus aureus.

Bartels MD, Petersen A, Worning P, Nielsen JB, Larner-Svensson H, Johansen HK, Andersen LP, Jarløv JO, Boye K, Larsen AR, Westh H.

J Clin Microbiol. 2014 Dec;52(12):4305-8. doi: 10.1128/JCM.01979-14. Epub 2014 Oct 8.

47.

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa.

Markussen T, Marvig RL, Gómez-Lozano M, Aanæs K, Burleigh AE, Høiby N, Johansen HK, Molin S, Jelsbak L.

MBio. 2014 Sep 16;5(5):e01592-14. doi: 10.1128/mBio.01592-14.

48.

Nystatin prophylaxis and treatment in severely immunodepressed patients.

Gøtzsche PC, Johansen HK.

Cochrane Database Syst Rev. 2014 Sep 4;(9):CD002033. doi: 10.1002/14651858.CD002033.pub2. Review.

PMID:
25188770
49.

Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients.

Johansen HK, Gøtzsche PC.

Cochrane Database Syst Rev. 2014 Sep 4;(9):CD000239. doi: 10.1002/14651858.CD000239.pub2. Review.

PMID:
25188769
50.

Routine versus selective antifungal administration for control of fungal infections in patients with cancer.

Gøtzsche PC, Johansen HK.

Cochrane Database Syst Rev. 2014 Sep 4;(9):CD000026. doi: 10.1002/14651858.CD000026.pub2. Review.

PMID:
25188768

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