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Items: 1 to 50 of 180

1.

Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism.

Johansson KE, Ståhl AL, Arvidsson I, Loos S, Tontanahal A, Rebetz J, Chromek M, Kristoffersson AC, Johannes L, Karpman D.

Sci Rep. 2019 Oct 7;9(1):14362. doi: 10.1038/s41598-019-50692-1.

2.

Shiga Toxin Induces Lipid Compression: A Mechanism for Generating Membrane Curvature.

Watkins EB, Majewski J, Chi EY, Gao H, Florent JC, Johannes L.

Nano Lett. 2019 Oct 9;19(10):7365-7369. doi: 10.1021/acs.nanolett.9b03001. Epub 2019 Sep 25.

PMID:
31538793
3.

Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury.

Morace I, Pilz R, Federico G, Jennemann R, Krunic D, Nordström V, von Gerichten J, Marsching C, Schießl IM, Müthing J, Wunder C, Johannes L, Sandhoff R, Gröne HJ.

Kidney Int. 2019 Aug;96(2):327-341. doi: 10.1016/j.kint.2019.02.010. Epub 2019 Feb 28.

4.

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells.

Dewulf M, Köster DV, Sinha B, Viaris de Lesegno C, Chambon V, Bigot A, Bensalah M, Negroni E, Tardif N, Podkalicka J, Johannes L, Nassoy P, Butler-Browne G, Lamaze C, Blouin CM.

Nat Commun. 2019 Apr 29;10(1):1974. doi: 10.1038/s41467-019-09405-5.

5.

2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology.

Lucchino M, Billet A, Versini A, Bavireddi H, Dasari BD, Debieu S, Colombeau L, Cañeque T, Wagner A, Masson G, Taran F, Karoyan P, Delepierre M, Gaillet C, Houdusse A, Britton S, Schmidt F, Florent JC, Belmont P, Monchaud D, Cossy J, Thomas C, Gautier A, Johannes L, Rodriguez R.

Chembiochem. 2019 Apr 1;20(7):968-973. doi: 10.1002/cbic.201900092. Epub 2019 Feb 25.

PMID:
30803119
6.

The 2018 biomembrane curvature and remodeling roadmap.

Bassereau P, Jin R, Baumgart T, Deserno M, Dimova R, Frolov VA, Bashkirov PV, Grubmüller H, Jahn R, Risselada HJ, Johannes L, Kozlov MM, Lipowsky R, Pucadyil TJ, Zeno WF, Stachowiak JC, Stamou D, Breuer A, Lauritsen L, Simon C, Sykes C, Voth GA, Weikl TR.

J Phys D Appl Phys. 2018 Aug;51(34). pii: 343001. doi: 10.1088/1361-6463/aacb98. Epub 2018 Jul 20.

7.

Retro Styles for Vesicle Coats.

Hurley JH, Johannes L.

Biochemistry. 2019 Feb 12;58(6):433-434. doi: 10.1021/acs.biochem.8b01271. Epub 2019 Jan 17. No abstract available.

PMID:
30653311
8.

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription.

Torrino S, Shen WW, Blouin CM, Mani SK, Viaris de Lesegno C, Bost P, Grassart A, Köster D, Valades-Cruz CA, Chambon V, Johannes L, Pierobon P, Soumelis V, Coirault C, Vassilopoulos S, Lamaze C.

J Cell Biol. 2018 Dec 3;217(12):4092-4105. doi: 10.1083/jcb.201801122. Epub 2018 Oct 22.

9.

Rapalog combined with CCR4 antagonist improves anticancer vaccines efficacy.

Beziaud L, Boullerot L, Tran T, Mansi L, Marie-Joseph EL, Ravel P, Johannes L, Bayry J, Tartour E, Adotévi O.

Int J Cancer. 2018 Dec 1;143(11):3008-3018. doi: 10.1002/ijc.31842. Epub 2018 Oct 1.

PMID:
30183073
10.

Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs.

Johannes L, Lucchino M.

Nucleic Acid Ther. 2018 Jun;28(3):178-193. doi: 10.1089/nat.2017.0716. Review.

11.

Galectins at a glance.

Johannes L, Jacob R, Leffler H.

J Cell Sci. 2018 May 1;131(9). pii: jcs208884. doi: 10.1242/jcs.208884. Review.

12.

MicroRNA 199a-5p Attenuates Retrograde Transport and Protects against Toxin-Induced Inhibition of Protein Biosynthesis.

Aranda JF, Rathjen S, Johannes L, Fernández-Hernando C.

Mol Cell Biol. 2018 May 15;38(11). pii: e00548-17. doi: 10.1128/MCB.00548-17. Print 2018 Jun 1.

13.

Clustering on Membranes: Fluctuations and More.

Johannes L, Pezeshkian W, Ipsen JH, Shillcock JC.

Trends Cell Biol. 2018 May;28(5):405-415. doi: 10.1016/j.tcb.2018.01.009. Epub 2018 Mar 1. Review.

PMID:
29502867
14.

Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation.

Carpier JM, Zucchetti AE, Bataille L, Dogniaux S, Shafaq-Zadah M, Bardin S, Lucchino M, Maurin M, Joannas LD, Magalhaes JG, Johannes L, Galli T, Goud B, Hivroz C.

J Exp Med. 2018 Apr 2;215(4):1245-1265. doi: 10.1084/jem.20162042. Epub 2018 Feb 12.

15.

Correction to Mechanism of Shiga Toxin Clustering on Membranes.

Pezeshkian W, Gao H, Arumugam S, Becken U, Bassereau P, Florent JC, Ipsen JH, Johannes L, Shillcock JC.

ACS Nano. 2018 Feb 27;12(2):2079. doi: 10.1021/acsnano.8b00537. Epub 2018 Jan 25. No abstract available.

16.

Increasing Diversity of Biological Membrane Fission Mechanisms.

Renard HF, Johannes L, Morsomme P.

Trends Cell Biol. 2018 Apr;28(4):274-286. doi: 10.1016/j.tcb.2017.12.001. Epub 2018 Jan 4. Review.

PMID:
29307448
17.

Glycosphingolipid metabolic reprogramming drives neural differentiation.

Russo D, Della Ragione F, Rizzo R, Sugiyama E, Scalabrì F, Hori K, Capasso S, Sticco L, Fioriniello S, De Gregorio R, Granata I, Guarracino MR, Maglione V, Johannes L, Bellenchi GC, Hoshino M, Setou M, D'Esposito M, Luini A, D'Angelo G.

EMBO J. 2018 Apr 3;37(7). pii: e97674. doi: 10.15252/embj.201797674. Epub 2017 Dec 27.

18.

Shiga Toxin-A Model for Glycolipid-Dependent and Lectin-Driven Endocytosis.

Johannes L.

Toxins (Basel). 2017 Oct 25;9(11). pii: E340. doi: 10.3390/toxins9110340. Review.

19.

A novel type of quantum dot-transferrin conjugate using DNA hybridization mimics intracellular recycling of endogenous transferrin.

Banerjee A, Grazon C, Pons T, Bhatia D, Valades-Cruz CA, Johannes L, Krishnan Y, Dubertret B.

Nanoscale. 2017 Oct 19;9(40):15453-15460. doi: 10.1039/c7nr05838a.

PMID:
28976518
20.

Endocytosis: Remote Control from Deep Inside.

Johannes L.

Curr Biol. 2017 Jul 10;27(13):R663-R666. doi: 10.1016/j.cub.2017.05.018.

21.

Friction Mediates Scission of Tubular Membranes Scaffolded by BAR Proteins.

Simunovic M, Manneville JB, Renard HF, Evergren E, Raghunathan K, Bhatia D, Kenworthy AK, Voth GA, Prost J, McMahon HT, Johannes L, Bassereau P, Callan-Jones A.

Cell. 2017 Jun 29;170(1):172-184.e11. doi: 10.1016/j.cell.2017.05.047. Epub 2017 Jun 22.

22.

Induction of resident memory T cells enhances the efficacy of cancer vaccine.

Nizard M, Roussel H, Diniz MO, Karaki S, Tran T, Voron T, Dransart E, Sandoval F, Riquet M, Rance B, Marcheteau E, Fabre E, Mandavit M, Terme M, Blanc C, Escudie JB, Gibault L, Barthes FLP, Granier C, Ferreira LCS, Badoual C, Johannes L, Tartour E.

Nat Commun. 2017 May 24;8:15221. doi: 10.1038/ncomms15221.

23.

Glycolipids and Lectins in Endocytic Uptake Processes.

Johannes L, Wunder C, Shafaq-Zadah M.

J Mol Biol. 2016 Oct 27. pii: S0022-2836(16)30453-3. doi: 10.1016/j.jmb.2016.10.027. [Epub ahead of print] Review.

PMID:
27984039
24.

Mechanism of Shiga Toxin Clustering on Membranes.

Pezeshkian W, Gao H, Arumugam S, Becken U, Bassereau P, Florent JC, Ipsen JH, Johannes L, Shillcock JC.

ACS Nano. 2017 Jan 24;11(1):314-324. doi: 10.1021/acsnano.6b05706. Epub 2016 Dec 16. Erratum in: ACS Nano. 2018 Feb 27;12(2):2079.

25.

Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex.

Chmiest D, Sharma N, Zanin N, Viaris de Lesegno C, Shafaq-Zadah M, Sibut V, Dingli F, Hupé P, Wilmes S, Piehler J, Loew D, Johannes L, Schreiber G, Lamaze C.

Nat Commun. 2016 Dec 5;7:13476. doi: 10.1038/ncomms13476.

26.

Retromer Sets a Trap for Endosomal Cargo Sorting.

Johannes L, Wunder C.

Cell. 2016 Dec 1;167(6):1452-1454. doi: 10.1016/j.cell.2016.11.026.

27.

Quantum dot-loaded monofunctionalized DNA icosahedra for single-particle tracking of endocytic pathways.

Bhatia D, Arumugam S, Nasilowski M, Joshi H, Wunder C, Chambon V, Prakash V, Grazon C, Nadal B, Maiti PK, Johannes L, Dubertret B, Krishnan Y.

Nat Nanotechnol. 2016 Dec;11(12):1112-1119. doi: 10.1038/nnano.2016.150. Epub 2016 Aug 22.

28.

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.

Daillère R, Vétizou M, Waldschmitt N, Yamazaki T, Isnard C, Poirier-Colame V, Duong CPM, Flament C, Lepage P, Roberti MP, Routy B, Jacquelot N, Apetoh L, Becharef S, Rusakiewicz S, Langella P, Sokol H, Kroemer G, Enot D, Roux A, Eggermont A, Tartour E, Johannes L, Woerther PL, Chachaty E, Soria JC, Golden E, Formenti S, Plebanski M, Madondo M, Rosenstiel P, Raoult D, Cattoir V, Boneca IG, Chamaillard M, Zitvogel L.

Immunity. 2016 Oct 18;45(4):931-943. doi: 10.1016/j.immuni.2016.09.009. Epub 2016 Oct 4.

29.

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.

Gupta N, Noël R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Liévin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D.

Chem Biol Interact. 2017 Apr 1;267:96-103. doi: 10.1016/j.cbi.2016.10.005. Epub 2016 Oct 3.

PMID:
27712998
30.

How curvature-generating proteins build scaffolds on membrane nanotubes.

Simunovic M, Evergren E, Golushko I, Prévost C, Renard HF, Johannes L, McMahon HT, Lorman V, Voth GA, Bassereau P.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11226-11231. Epub 2016 Sep 21.

31.

Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes.

Rout L, Parida BB, Florent JC, Johannes L, Choudhury SK, Phaomei G, Scanlon J, Bertounesque E.

Chemistry. 2016 Oct 10;22(42):14812-14815. doi: 10.1002/chem.201603003. Epub 2016 Aug 30.

PMID:
27504988
32.

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation.

Blouin CM, Hamon Y, Gonnord P, Boularan C, Kagan J, Viaris de Lesegno C, Ruez R, Mailfert S, Bertaux N, Loew D, Wunder C, Johannes L, Vogt G, Contreras FX, Marguet D, Casanova JL, Galès C, He HT, Lamaze C.

Cell. 2016 Aug 11;166(4):920-934. doi: 10.1016/j.cell.2016.07.003. Epub 2016 Aug 4.

33.

Membrane invagination induced by Shiga toxin B-subunit: from molecular structure to tube formation.

Pezeshkian W, Hansen AG, Johannes L, Khandelia H, Shillcock JC, Kumar PB, Ipsen JH.

Soft Matter. 2016 Jun 21;12(23):5164-71. doi: 10.1039/c6sm00464d. Epub 2016 Apr 12.

PMID:
27070906
34.

A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu-Expressing Tumor in HLA-A2 Transgenic Mice.

Tran T, Diniz MO, Dransart E, Gey A, Merillon N, Lone YC, Godefroy S, Sibley C, Ferreira LC, Medioni J, Oudard S, Johannes L, Tartour E.

Clin Cancer Res. 2016 Aug 15;22(16):4133-44. doi: 10.1158/1078-0432.CCR-16-0044. Epub 2016 Mar 22.

35.

Gastric Adenocarcinomas Express the Glycosphingolipid Gb3/CD77: Targeting of Gastric Cancer Cells with Shiga Toxin B-Subunit.

Geyer PE, Maak M, Nitsche U, Perl M, Novotny A, Slotta-Huspenina J, Dransart E, Holtorf A, Johannes L, Janssen KP.

Mol Cancer Ther. 2016 May;15(5):1008-17. doi: 10.1158/1535-7163.MCT-15-0633. Epub 2016 Jan 29.

36.

Persistent cell migration and adhesion rely on retrograde transport of β(1) integrin.

Shafaq-Zadah M, Gomes-Santos CS, Bardin S, Maiuri P, Maurin M, Iranzo J, Gautreau A, Lamaze C, Caswell P, Goud B, Johannes L.

Nat Cell Biol. 2016 Jan;18(1):54-64. doi: 10.1038/ncb3287. Epub 2015 Dec 7.

PMID:
26641717
37.

Targeted Shiga toxin-drug conjugates prepared via Cu-free click chemistry.

Kostova V, Dransart E, Azoulay M, Brulle L, Bai SK, Florent JC, Johannes L, Schmidt F.

Bioorg Med Chem. 2015 Nov 15;23(22):7150-7. doi: 10.1016/j.bmc.2015.10.010. Epub 2015 Oct 8.

PMID:
26507432
38.

Slow Relaxation of Shape and Orientational Texture in Membrane Gel Domains.

Jeppesen JC, Solovyeva V, Brewer JR, Johannes L, Hansen PL, Simonsen AC.

Langmuir. 2015 Nov 24;31(46):12699-707. doi: 10.1021/acs.langmuir.5b03168. Epub 2015 Nov 11.

PMID:
26501924
39.

Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site.

Thoreau M, Penny HL, Tan K, Regnier F, Weiss JM, Lee B, Johannes L, Dransart E, Le Bon A, Abastado JP, Tartour E, Trautmann A, Bercovici N.

Oncotarget. 2015 Sep 29;6(29):27832-46. doi: 10.18632/oncotarget.4940.

40.

Shiga toxin stimulates clathrin-independent endocytosis of the VAMP2, VAMP3 and VAMP8 SNARE proteins.

Renard HF, Garcia-Castillo MD, Chambon V, Lamaze C, Johannes L.

J Cell Sci. 2015 Aug 1;128(15):2891-902. doi: 10.1242/jcs.171116. Epub 2015 Jun 12.

41.

Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin.

Abdelkafi H, Michau A, Clerget A, Buisson DA, Johannes L, Gillet D, Barbier J, Cintrat JC.

ChemMedChem. 2015 Jul;10(7):1153-6. doi: 10.1002/cmdc.201500139. Epub 2015 Jun 1.

PMID:
26033849
42.

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli.

Secher T, Shima A, Hinsinger K, Cintrat JC, Johannes L, Barbier J, Gillet D, Oswald E.

Antimicrob Agents Chemother. 2015 Aug;59(8):5010-3. doi: 10.1128/AAC.00455-15. Epub 2015 May 18.

43.

Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin.

Garcia-Castillo MD, Tran T, Bobard A, Renard HF, Rathjen SJ, Dransart E, Stechmann B, Lamaze C, Lord M, Cintrat JC, Enninga J, Tartour E, Johannes L.

J Cell Sci. 2015 Jul 1;128(13):2373-87. doi: 10.1242/jcs.169383. Epub 2015 May 14.

44.

Building endocytic pits without clathrin.

Johannes L, Parton RG, Bassereau P, Mayor S.

Nat Rev Mol Cell Biol. 2015 May;16(5):311-21. doi: 10.1038/nrm3968. Epub 2015 Apr 10. Review.

PMID:
25857812
45.

A new delivery system for auristatin in STxB-drug conjugate therapy.

Batisse C, Dransart E, Ait Sarkouh R, Brulle L, Bai SK, Godefroy S, Johannes L, Schmidt F.

Eur J Med Chem. 2015 May 5;95:483-91. doi: 10.1016/j.ejmech.2015.03.047. Epub 2015 Mar 28.

PMID:
25847766
46.

Synergy of Radiotherapy and a Cancer Vaccine for the Treatment of HPV-Associated Head and Neck Cancer.

Mondini M, Nizard M, Tran T, Mauge L, Loi M, Clémenson C, Dugue D, Maroun P, Louvet E, Adam J, Badoual C, Helley D, Dransart E, Johannes L, Vozenin MC, Perfettini JL, Tartour E, Deutsch E.

Mol Cancer Ther. 2015 Jun;14(6):1336-45. doi: 10.1158/1535-7163.MCT-14-1015. Epub 2015 Apr 1.

47.

Membrane traffic: endocytotic dynamics and regulation.

Nichols BJ, Johannes L.

Mol Biol Cell. 2015 Mar 15;26(6):1008. doi: 10.1091/mbc.E15-01-0022. No abstract available.

48.

The effects of globotriaosylceramide tail saturation level on bilayer phases.

Pezeshkian W, Chaban VV, Johannes L, Shillcock J, Ipsen JH, Khandelia H.

Soft Matter. 2015 Feb 4;11(7):1352-61. doi: 10.1039/c4sm02456g.

PMID:
25575293
49.

Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis.

Renard HF, Simunovic M, Lemière J, Boucrot E, Garcia-Castillo MD, Arumugam S, Chambon V, Lamaze C, Wunder C, Kenworthy AK, Schmidt AA, McMahon HT, Sykes C, Bassereau P, Johannes L.

Nature. 2015 Jan 22;517(7535):493-6. doi: 10.1038/nature14064. Epub 2014 Dec 17.

50.

Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds.

Stimmer L, Dehay S, Nemati F, Massonnet G, Richon S, Decaudin D, Klijanienko J, Johannes L.

BMC Cancer. 2014 Dec 4;14:916. doi: 10.1186/1471-2407-14-916.

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