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Items: 8


Impact of Precipitation of Antibody Therapeutics After Subcutaneous Injection on Pharmacokinetics and Immunogenicity.

Kinderman F, Yerby B, Jawa V, Joubert MK, Joh NH, Malella J, Herskovitz J, Xie J, Ferbas J, McBride HJ.

J Pharm Sci. 2019 Jun;108(6):1953-1963. doi: 10.1016/j.xphs.2019.01.015. Epub 2019 Jan 23.


Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.

Joh NH, Grigoryan G, Wu Y, DeGrado WF.

Philos Trans R Soc Lond B Biol Sci. 2017 Aug 5;372(1726). pii: 20160214. doi: 10.1098/rstb.2016.0214. Review.


De novo design of a transmembrane Zn²⁺-transporting four-helix bundle.

Joh NH, Wang T, Bhate MP, Acharya R, Wu Y, Grabe M, Hong M, Grigoryan G, DeGrado WF.

Science. 2014 Dec 19;346(6216):1520-4. doi: 10.1126/science.1261172.


Probing membrane protein unfolding with pulse proteolysis.

Schlebach JP, Kim MS, Joh NH, Bowie JU, Park C.

J Mol Biol. 2011 Mar 4;406(4):545-51. doi: 10.1016/j.jmb.2010.12.018. Epub 2010 Dec 28. Review.


Structural imperatives impose diverse evolutionary constraints on helical membrane proteins.

Oberai A, Joh NH, Pettit FK, Bowie JU.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17747-50. doi: 10.1073/pnas.0906390106. Epub 2009 Oct 6.


Similar energetic contributions of packing in the core of membrane and water-soluble proteins.

Joh NH, Oberai A, Yang D, Whitelegge JP, Bowie JU.

J Am Chem Soc. 2009 Aug 12;131(31):10846-7. doi: 10.1021/ja904711k.


Methods for measuring the thermodynamic stability of membrane proteins.

Hong H, Joh NH, Bowie JU, Tamm LK.

Methods Enzymol. 2009;455:213-36. doi: 10.1016/S0076-6879(08)04208-0.


Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins.

Joh NH, Min A, Faham S, Whitelegge JP, Yang D, Woods VL, Bowie JU.

Nature. 2008 Jun 26;453(7199):1266-70. doi: 10.1038/nature06977. Epub 2008 May 25.

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