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Items: 1 to 50 of 154

1.

[Treatment of Advanced Prostate Carcinoma - an Interdisciplinary Recommendation].

Omlin A, Spahn M, Beyer J, Eberli D, Gillessen S, Jochum W, Kueng M, Nitzsche E, Rentsch CA, Roggero E, Schmid HP, Stenner F, Templeton AJ, Wild D, Wyler S, Zwahlen D, Cathomas R.

Praxis (Bern 1994). 2018 Sep;107(19):1043-1051. doi: 10.1024/1661-8157/a003054. Review. German. No abstract available.

PMID:
30227804
2.

Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma.

Plath M, Broglie MA, Förbs D, Stoeckli SJ, Jochum W.

J Otolaryngol Head Neck Surg. 2018 Sep 6;47(1):53. doi: 10.1186/s40463-018-0298-3.

3.

Endoscopic Treatment of Early Barrett's Adenocarcinoma and Dysplasia: Focus on Submucosal Cancer.

Frei N, Frei R, Semadeni GM, Jochum W, Brand S, Borovicka J.

Digestion. 2018 Sep 3:1-8. doi: 10.1159/000492217. [Epub ahead of print]

PMID:
30176662
4.

Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC).

Schmid S, Diem S, Li Q, Krapf M, Flatz L, Leschka S, Desbiolles L, Klingbiel D, Jochum W, Früh M.

Cancer Immunol Immunother. 2018 Dec;67(12):1825-1832. doi: 10.1007/s00262-018-2239-4. Epub 2018 Aug 31.

PMID:
30171269
5.

Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers.

Guo T, Li L, Zhong Q, Rupp NJ, Charmpi K, Wong CE, Wagner U, Rueschoff JH, Jochum W, Fankhauser CD, Saba K, Poyet C, Wild PJ, Aebersold R, Beyer A.

Life Sci Alliance. 2018 May 29;1(2). pii: e201800042. doi: 10.26508/lsa.201800042.

6.

The prognostic value of signet ring cell histology in stage I/II colon cancer-a population-based, propensity score-matched analysis.

Ackermann CJ, Guller U, Jochum W, Schmied BM, Warschkow R.

Int J Colorectal Dis. 2018 Jun 7. doi: 10.1007/s00384-018-3096-5. [Epub ahead of print]

PMID:
29881972
7.

Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.

Zhong Q, Wagner U, Kurt H, Molinari F, Cathomas G, Komminoth P, Barman-Aksözen J, Schneider-Yin X, Rey JP, Vassella E, Rogel U, Diebold J, McKee T, Jochum W, Kashofer K, Hofman P, Zischka M, Moch H, Rechsteiner M, Wild PJ.

Pathol Res Pract. 2018 Jul;214(7):957-963. doi: 10.1016/j.prp.2018.05.020. Epub 2018 May 22.

PMID:
29807778
8.

Anti-PD-1 Therapy Leads to Near-Complete Remission in a Patient with Metastatic Basal Cell Carcinoma.

Fischer S, Ali OH, Jochum W, Kluckert T, Flatz L, Siano M.

Oncol Res Treat. 2018;41(6):391-394. doi: 10.1159/000487084. Epub 2018 May 3.

PMID:
29734143
9.

Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness.

Boesch M, Onder L, Cheng HW, Novkovic M, Mörbe U, Sopper S, Gastl G, Jochum W, Ruhstaller T, Knauer M, Ludewig B.

Oncoimmunology. 2018 Jan 3;7(4):e1414129. doi: 10.1080/2162402X.2017.1414129. eCollection 2018.

10.

CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses.

Cheng HW, Onder L, Cupovic J, Boesch M, Novkovic M, Pikor N, Tarantino I, Rodriguez R, Schneider T, Jochum W, Brutsche M, Ludewig B.

J Allergy Clin Immunol. 2018 Oct;142(4):1257-1271.e4. doi: 10.1016/j.jaci.2017.12.998. Epub 2018 Jan 31.

11.

Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma.

Ohe C, Smith SC, Sirohi D, Divatia M, de Peralta-Venturina M, Paner GP, Agaimy A, Amin MB, Argani P, Chen YB, Cheng L, Colecchia M, Compérat E, Werneck da Cunha I, Epstein JI, Gill AJ, Hes O, Hirsch MS, Jochum W, Kunju LP, Maclean F, Magi-Galluzzi C, McKenney JK, Mehra R, Nesi G, Osunkoya AO, Picken MM, Rao P, Reuter VE, de Oliveira Salles PG, Schultz L, Tickoo SK, Tomlins SA, Trpkov K, Amin MB.

Am J Surg Pathol. 2018 Mar;42(3):279-292. doi: 10.1097/PAS.0000000000001000.

PMID:
29309300
12.

Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study.

Diebold M, Soltermann A, Hottinger S, Haile SR, Bubendorf L, Komminoth P, Jochum W, Grobholz R, Theegarten D, Berezowska S, Darwiche K, Oezkan F, Kohler M, Franzen DP.

Respir Res. 2017 Dec 16;18(1):210. doi: 10.1186/s12931-017-0693-8.

13.

Individualized treatment approaches for Langerhans cell histiocytosis.

Roider E, Signer C, Fehrenbacher B, Metzler G, Schaller M, Kamarachev J, Kerl K, Balabanov S, Jochum W, Hoetzenecker W, Cozzio A, French LE, Dummer R, Guenova E.

Br J Dermatol. 2018 Jun;178(6):1423-1424. doi: 10.1111/bjd.16171. Epub 2018 Mar 23. No abstract available.

14.

Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease.

Diem S, Hasan Ali O, Ackermann CJ, Bomze D, Koelzer VH, Jochum W, Speiser DE, Mertz KD, Flatz L.

Cancer Immunol Immunother. 2018 Jan;67(1):39-45. doi: 10.1007/s00262-017-2061-4. Epub 2017 Sep 11.

PMID:
28894934
15.

Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab.

Diem S, Schmid S, Krapf M, Flatz L, Born D, Jochum W, Templeton AJ, Früh M.

Lung Cancer. 2017 Sep;111:176-181. doi: 10.1016/j.lungcan.2017.07.024. Epub 2017 Jul 24.

PMID:
28838390
16.

Recurrent Dystrophic Calcification of the Prostatic Resection Cavity After Transurethral Resection of the Prostate: Clinical Presentation and Endoscopic Management.

Zumstein V, Betschart P, Müllhaupt G, Jochum W, Schmid HP, Abt D.

J Endourol Case Rep. 2017 Jun 1;3(1):81-83. doi: 10.1089/cren.2017.0058. eCollection 2017.

17.

Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery.

Broglie MA, Stoeckli SJ, Sauter R, Pasche P, Reinhard A, de Leval L, Huber GF, Pezier TF, Soltermann A, Giger R, Arnold A, Dettmer M, Arnoux A, Müller M, Spreitzer S, Lang F, Lutchmaya M, Stauffer E, Espeli V, Martucci F, Bongiovanni M, Foerbs D, Jochum W.

Head Neck. 2017 Oct;39(10):2004-2015. doi: 10.1002/hed.24865. Epub 2017 Jul 10.

PMID:
28691255
18.

Evaluation of type-specific antibodies to high risk-human papillomavirus (HPV) proteins in patients with oropharyngeal cancer.

Broglie MA, Jochum W, Michel A, Waterboer T, Foerbs D, Schoenegg R, Stoeckli SJ, Pawlita M, Holzinger D.

Oral Oncol. 2017 Jul;70:43-50. doi: 10.1016/j.oraloncology.2017.05.010. Epub 2017 May 25.

PMID:
28622890
19.

Epidermal growth factor receptor and anaplastic lymphoma kinase testing and mutation prevalence in patients with advanced non-small cell lung cancer in Switzerland: A comprehensive evaluation of real world practices.

Ess SM, Herrmann C, Frick H, Krapf M, Cerny T, Jochum W, Früh M.

Eur J Cancer Care (Engl). 2017 Nov;26(6). doi: 10.1111/ecc.12721. Epub 2017 May 30.

PMID:
28557060
20.

Impact of particle size and surface modification on gold nanoparticle penetration into human placental microtissues.

Muoth C, Großgarten M, Karst U, Ruiz J, Astruc D, Moya S, Diener L, Grieder K, Wichser A, Jochum W, Wick P, Buerki-Thurnherr T.

Nanomedicine (Lond). 2017 May;12(10):1119-1133. doi: 10.2217/nnm-2017-0428. Epub 2017 Apr 27.

PMID:
28447888
21.

Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes.

Burmeister K, Quagliata L, Andreozzi M, Eppenberger-Castori S, Matter MS, Perrina V, Grobholz R, Jochum W, Horber D, Moosmann P, Lehmann F, Köberle D, Ng CK, Piscuoglio S, Tornillo L, Terracciano LM.

PLoS One. 2017 Apr 12;12(4):e0175563. doi: 10.1371/journal.pone.0175563. eCollection 2017.

22.

Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura.

Brock M, Hottinger S, Diebold M, Soltermann A, Jochum W, Kohler M, Huber LC, Franzen DP.

Respir Res. 2017 Mar 2;18(1):43. doi: 10.1186/s12931-017-0528-7.

23.

Clinical Outcome of ALK-Positive Non-Small Cell Lung Cancer (NSCLC) Patients with De Novo EGFR or KRAS Co-Mutations Receiving Tyrosine Kinase Inhibitors (TKIs).

Schmid S, Gautschi O, Rothschild S, Mark M, Froesch P, Klingbiel D, Reichegger H, Jochum W, Diebold J, Früh M.

J Thorac Oncol. 2017 Apr;12(4):681-688. doi: 10.1016/j.jtho.2016.12.003. Epub 2016 Dec 19.

24.

Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer.

Hasan Ali O, Diem S, Markert E, Jochum W, Kerl K, French LE, Speiser DE, Früh M, Flatz L.

Oncoimmunology. 2016 Sep 19;5(11):e1231292. doi: 10.1080/2162402X.2016.1231292. eCollection 2016.

25.

Correction: Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart.

Sibilia M, Wagner B, Hoebertz A, Elliott C, Marino S, Jochum W, Wagner EF.

Development. 2016 Dec 15;143(24):4755. No abstract available.

26.

Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci: A Frequent Morphologic Pattern of Fumarate Hydratase-deficient Renal Cell Carcinoma.

Smith SC, Trpkov K, Chen YB, Mehra R, Sirohi D, Ohe C, Cani AK, Hovelson DH, Omata K, McHugh JB, Jochum W, Colecchia M, Amin M, Divatia MK, Hes O, Menon S, Werneck da Cunha I, Tripodi S, Brimo F, Gill AJ, Osunkoya AO, Magi-Galluzzi C, Sibony M, Williamson SR, Nesi G, Picken MM, Maclean F, Agaimy A, Cheng L, Epstein JI, Reuter VE, Tickoo SK, Tomlins SA, Amin MB.

Am J Surg Pathol. 2016 Nov;40(11):1457-1472.

27.

A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment.

Muoth C, Wichser A, Monopoli M, Correia M, Ehrlich N, Loeschner K, Gallud A, Kucki M, Diener L, Manser P, Jochum W, Wick P, Buerki-Thurnherr T.

Nanoscale. 2016 Oct 6;8(39):17322-17332.

PMID:
27714104
28.

Rapid Intracranial Response to Osimertinib in a Patient with Epidermal Growth Factor Receptor T790M-Positive Adenocarcinoma of the Lung.

Reichegger H, Jochum W, Förbs D, Hader C, Früh M.

Oncol Res Treat. 2016;39(7-8):461-3. doi: 10.1159/000446759. Epub 2016 Jun 15.

29.

Reproducible Tissue Homogenization and Protein Extraction for Quantitative Proteomics Using MicroPestle-Assisted Pressure-Cycling Technology.

Shao S, Guo T, Gross V, Lazarev A, Koh CC, Gillessen S, Joerger M, Jochum W, Aebersold R.

J Proteome Res. 2016 Jun 3;15(6):1821-9. doi: 10.1021/acs.jproteome.5b01136. Epub 2016 May 10.

PMID:
27098501
30.

Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity.

Zhong Q, Rüschoff JH, Guo T, Gabrani M, Schüffler PJ, Rechsteiner M, Liu Y, Fuchs TJ, Rupp NJ, Fankhauser C, Buhmann JM, Perner S, Poyet C, Blattner M, Soldini D, Moch H, Rubin MA, Noske A, Rüschoff J, Haffner MC, Jochum W, Wild PJ.

Sci Rep. 2016 Apr 7;6:24146. doi: 10.1038/srep24146.

31.

NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial.

Endris V, Stenzinger A, Pfarr N, Penzel R, Möbs M, Lenze D, Darb-Esfahani S, Hummel M, Sabine-Merkelbach-Bruse, Jung A, Lehmann U, Kreipe H, Kirchner T, Büttner R, Jochum W, Höfler G, Dietel M, Weichert W, Schirmacher P.

Virchows Arch. 2016 Jun;468(6):697-705. doi: 10.1007/s00428-016-1919-8. Epub 2016 Mar 22.

PMID:
27003155
32.

Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2).

Feilchenfeldt J, Varga Z, Siano M, Grabsch HI, Held U, Schuknecht B, Trip A, Hamaguchi T, Gut P, Balague O, Khanfir K, Diebold J, Jochum W, Shoji H, Kushima R, Wagner D, Shimada Y, Cats A, Knuth A, Moch H, Aebi S, Hofer S.

Br J Cancer. 2015 Dec 22;113(12):1747. doi: 10.1038/bjc.2015.458. No abstract available.

33.

Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.

Schmid P, Bregenzer A, Huber M, Rauch A, Jochum W, Müllhaupt B, Vernazza P, Opravil M, Weber R; Swiss HIV Cohort Study.

PLoS One. 2015 Sep 29;10(9):e0138838. doi: 10.1371/journal.pone.0138838. eCollection 2015.

34.

Brush cytology for the detection of high-risk HPV infection in oropharyngeal squamous cell carcinoma.

Broglie MA, Jochum W, Förbs D, Schönegg R, Stoeckli SJ.

Cancer Cytopathol. 2015 Dec;123(12):732-8. doi: 10.1002/cncy.21606. Epub 2015 Sep 8.

35.

Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2).

Feilchenfeldt J, Varga Z, Siano M, Grabsch HI, Held U, Schuknecht B, Trip A, Hamaguchi T, Gut P, Balague O, Khanfir K, Diebold J, Jochum W, Shoji H, Kushima R, Wagner D, Shimada Y, Cats A, Knuth A, Moch H, Aebi S, Hofer S.

Br J Cancer. 2015 Sep 1;113(5):716-21. doi: 10.1038/bjc.2015.279. Epub 2015 Aug 27. Erratum in: Br J Cancer. 2015 Dec 22;113(12):1747.

36.

Minimal sample requirement for highly multiplexed protein quantification in cell lines and tissues by PCT-SWATH mass spectrometry.

Shao S, Guo T, Koh CC, Gillessen S, Joerger M, Jochum W, Aebersold R.

Proteomics. 2015 Nov;15(21):3711-21. doi: 10.1002/pmic.201500161. Epub 2015 Sep 10.

PMID:
26287124
37.

Transfer studies of polystyrene nanoparticles in the ex vivo human placenta perfusion model: key sources of artifacts.

Grafmueller S, Manser P, Diener L, Maurizi L, Diener PA, Hofmann H, Jochum W, Krug HF, Buerki-Thurnherr T, von Mandach U, Wick P.

Sci Technol Adv Mater. 2015 Jul 16;16(4):044602. eCollection 2015 Aug.

38.

[How is agonizing leg pain associated with an intrauterine device?].

Jäckel K, Braschler T, Jochum W, Hülder T, Knechtle B.

Praxis (Bern 1994). 2015 May 6;104(10):517-22. doi: 10.1024/1661-8157/a002002. German. Erratum in: Praxis (Bern 1994). 2015 May 20;104(11):542.

PMID:
26098054
39.

Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended.

Savic S, Diebold J, Zimmermann AK, Jochum W, Baschiera B, Grieshaber S, Tornillo L, Bisig B, Kerr K, Bubendorf L.

Lung Cancer. 2015 Aug;89(2):104-9. doi: 10.1016/j.lungcan.2015.05.012. Epub 2015 May 21.

PMID:
26056079
40.

Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model.

Grafmueller S, Manser P, Diener L, Diener PA, Maeder-Althaus X, Maurizi L, Jochum W, Krug HF, Buerki-Thurnherr T, von Mandach U, Wick P.

Environ Health Perspect. 2015 Dec;123(12):1280-6. doi: 10.1289/ehp.1409271. Epub 2015 May 8.

41.

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps.

Guo T, Kouvonen P, Koh CC, Gillet LC, Wolski WE, Röst HL, Rosenberger G, Collins BC, Blum LC, Gillessen S, Joerger M, Jochum W, Aebersold R.

Nat Med. 2015 Apr;21(4):407-13. doi: 10.1038/nm.3807. Epub 2015 Mar 2.

42.

Impact of clinical risk scores and BRAF V600E mutation status on outcome in papillary thyroid cancer.

Niederer-Wüst SM, Jochum W, Förbs D, Brändle M, Bilz S, Clerici T, Oettli R, Müller J, Haile SR, Ess S, Stoeckli SJ, Broglie MA.

Surgery. 2015 Jan;157(1):119-25. doi: 10.1016/j.surg.2014.07.015.

PMID:
25482468
43.

Histopathological mapping of metastatic tumor cells in sentinel lymph nodes of oral and oropharyngeal squamous cell carcinomas.

Denoth S, Broglie MA, Haerle SK, Huber GF, Haile SR, Soltermann A, Jochum W, Stoeckli SJ.

Head Neck. 2015 Oct;37(10):1477-82. doi: 10.1002/hed.23782. Epub 2014 Sep 12.

PMID:
24890082
44.

EGFR expression and copy number changes in low T-stage oral squamous cell carcinomas.

Rössle M, Weber CS, Züllig L, Graf N, Jochum W, Stöckli SJ, Moch H, Huber GF.

Histopathology. 2013 Aug;63(2):271-8. doi: 10.1111/his.12175. Epub 2013 Jun 13.

PMID:
23763474
45.

Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing.

V Laffert M, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, Schildhaus HU, Merkelbach-Bruse S, Büttner R, Reu S, Kerler R, Jung A, Kirchner T, Wölfel C, Petersen I, Rodriguez R, Jochum W, Bartsch H, Fisseler-Eckhoff A, Berg E, Lenze D, Dietel M, Hummel M.

Lung Cancer. 2013 Aug;81(2):200-6. doi: 10.1016/j.lungcan.2013.04.015. Epub 2013 May 10.

PMID:
23669200
46.

Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies.

Ohlschlegel C, Kradolfer D, Hell M, Jochum W.

BMC Clin Pathol. 2013 Apr 20;13:13. doi: 10.1186/1472-6890-13-13.

47.

High sex determining region Y-box 2 expression is a negative predictor of occult lymph node metastasis in early squamous cell carcinomas of the oral cavity.

Züllig L, Roessle M, Weber C, Graf N, Haerle SK, Jochum W, Stoeckli SJ, Moch H, Huber GF.

Eur J Cancer. 2013 May;49(8):1915-22. doi: 10.1016/j.ejca.2013.01.005. Epub 2013 Feb 12.

PMID:
23414798
48.

Reproducibility of immunohistochemical scoring for epidermal growth factor receptor expression in non-small cell lung cancer: round robin test.

Rüschoff J, Kerr KM, Grote HJ, Middel P, von Heydebreck A, Alves VA, Baldus SE, Büttner R, Carvalho L, Fink L, Jochum W, Lo AW, López-Ríos F, Marx A, Molina TJ, Olszewski WT, Rieker RJ, Volante M, Thunnissen E, Wrba F, Celik I, Störkel S.

Arch Pathol Lab Med. 2013 Sep;137(9):1255-61. doi: 10.5858/arpa.2012-0605-OA. Epub 2012 Dec 27.

PMID:
23270410
49.

Quantification of coronary artery stenosis with high-resolution CT in comparison with histopathology in an ex vivo study.

Dettmer M, Glaser-Gallion N, Stolzmann P, Glaser-Gallion F, Fornaro J, Feuchtner G, Jochum W, Alkadhi H, Wildermuth S, Leschka S.

Eur J Radiol. 2013 Feb;82(2):264-9. doi: 10.1016/j.ejrad.2012.09.021. Epub 2012 Oct 29.

PMID:
23116807
50.

Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship.

Gupta R, Billis A, Shah RB, Moch H, Osunkoya AO, Jochum W, Hes O, Bacchi CE, de Castro MG, Hansel DE, Zhou M, Vankalakunti M, Salles PG, Cabrera RA, Gown AM, Amin MB.

Am J Surg Pathol. 2012 Sep;36(9):1265-78.

PMID:
22895263

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