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Items: 15

1.

In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline.

Pokorna Z, Jirkovsky E, Hlavackova M, Jansova H, Jirkovska A, Lencova-Popelova O, Brazdova P, Kubes J, Sotakova-Kasparova D, Mazurova Y, Adamcova M, Vostatkova L, Holzerova K, Kolar F, Simunek T, Sterba M.

Clin Sci (Lond). 2019 Aug 27;133(16):1827-1844. doi: 10.1042/CS20190139. Print 2019 Aug 30.

PMID:
31409729
2.

Pharmacokinetics of the Cardioprotective Drug Dexrazoxane and Its Active Metabolite ADR-925 with Focus on Cardiomyocytes and the Heart.

Jirkovský E, Jirkovská A, Bureš J, Chládek J, Lenčová O, Stariat J, Pokorná Z, Karabanovich G, Roh J, Brázdová P, Šimůnek T, Kovaříková P, Štěrba M.

J Pharmacol Exp Ther. 2018 Mar;364(3):433-446. doi: 10.1124/jpet.117.244848. Epub 2017 Dec 22.

PMID:
29273587
3.

Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?

Lenčová-Popelová O, Jansová H, Jirkovský E, Bureš J, Jirkovská-Vávrová A, Mazurová Y, Reimerová P, Vostatková L, Adamcová M, Hroch M, Pokorná Z, Kovaříková P, Šimůnek T, Štěrba M.

Toxicology. 2016 Nov 30;372:52-63. doi: 10.1016/j.tox.2016.11.002. Epub 2016 Nov 2.

PMID:
27816693
4.

Cardiac troponins--Translational biomarkers in cardiology: Theory and practice of cardiac troponin high-sensitivity assays.

Adamcova M, Popelova-Lencova O, Jirkovsky E, Simko F, Gersl V, Sterba M.

Biofactors. 2016 Mar-Apr;42(2):133-48. doi: 10.1002/biof.1261. Epub 2016 Feb 15. Review.

PMID:
26876101
5.

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane.

Lenčová-Popelová O, Jirkovský E, Jansová H, Jirkovská-Vávrová A, Vostatková-Tichotová L, Mazurová Y, Adamcová M, Chládek J, Hroch M, Pokorná Z, Geršl V, Šimůnek T, Štěrba M.

J Mol Cell Cardiol. 2016 Feb;91:92-103. doi: 10.1016/j.yjmcc.2015.12.021. Epub 2015 Dec 23.

PMID:
26724189
6.

CLINICAL AND LABORATORY FEATURES OF ACUTE VIRAL GASTROENTERITIS IN ADULTS, RESIDENTS OF NOVOSIBIRSK.

Krasnova EI, Khokhlova NI, Jirkovsky EV, Kapustin DV, Sokolov SN, Tikunova NV, Pozdnvakova LL, Kuznetsova IY.

Eksp Klin Gastroenterol. 2016;(9):14-18. English, Russian.

PMID:
29889389
7.

Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value.

Adamcova M, Lencova-Popelova O, Jirkovsky E, Mazurova Y, Palicka V, Simko F, Gersl V, Sterba M.

Int J Cardiol. 2015 Dec 15;201:358-67. doi: 10.1016/j.ijcard.2015.07.103. Epub 2015 Aug 4.

PMID:
26310978
8.

Molecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up.

Lenčová-Popelová O, Jirkovský E, Mazurová Y, Lenčo J, Adamcová M, Šimůnek T, Geršl V, Štěrba M.

PLoS One. 2014 May 7;9(5):e96055. doi: 10.1371/journal.pone.0096055. eCollection 2014.

9.

Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits.

Jirkovský E, Lenčová-Popelová O, Hroch M, Adamcová M, Mazurová Y, Vávrová J, Mičuda S, Šimůnek T, Geršl V, Štěrba M.

Toxicology. 2013 Sep 15;311(3):191-204. doi: 10.1016/j.tox.2013.06.012. Epub 2013 Jul 4.

PMID:
23831762
10.

Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways.

Jirkovsky E, Popelová O, Kriváková-Stanková P, Vávrová A, Hroch M, Hasková P, Brcáková-Dolezelová E, Micuda S, Adamcová M, Simůnek T, Cervinková Z, Gersl V, Sterba M.

J Pharmacol Exp Ther. 2012 Nov;343(2):468-78. doi: 10.1124/jpet.112.198358. Epub 2012 Aug 22.

PMID:
22915767
11.

Oxidative stress, redox signaling, and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection.

Stěrba M, Popelová O, Vávrová A, Jirkovský E, Kovaříková P, Geršl V, Simůnek T.

Antioxid Redox Signal. 2013 Mar 10;18(8):899-929. doi: 10.1089/ars.2012.4795. Epub 2012 Oct 12. Review.

12.

Daunorubicin does not induce immunohistochemically detectable endothelial dysfunction in rabbit aorta and femoral artery.

Nachtigal P, Sterba M, Popelová O, Večeřová L, Kudláčková Z, Jirkovský E, Geršl V.

Histol Histopathol. 2011 May;26(5):551-62. doi: 10.14670/HH-26.551.

PMID:
21432770
13.

Proteomic insights into chronic anthracycline cardiotoxicity.

Stěrba M, Popelová O, Lenčo J, Fučíková A, Brčáková E, Mazurová Y, Jirkovský E, Simůnek T, Adamcová M, Mičuda S, Stulík J, Geršl V.

J Mol Cell Cardiol. 2011 May;50(5):849-62. doi: 10.1016/j.yjmcc.2011.01.018. Epub 2011 Jan 31.

PMID:
21284945
14.

In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity.

Vávrová A, Popelová O, Stěrba M, Jirkovský E, Hašková P, Mertlíková-Kaiserová H, Geršl V, Simůnek T.

Arch Toxicol. 2011 May;85(5):525-35. doi: 10.1007/s00204-010-0615-8. Epub 2010 Nov 3.

PMID:
21046361
15.

Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury.

Bendova P, Mackova E, Haskova P, Vavrova A, Jirkovsky E, Sterba M, Popelova O, Kalinowski DS, Kovarikova P, Vavrova K, Richardson DR, Simunek T.

Chem Res Toxicol. 2010 Jun 21;23(6):1105-14. doi: 10.1021/tx100125t.

PMID:
20521781

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