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Items: 25


TBCRC023: A Randomized Phase II Neoadjuvant Trial of Lapatinib Plus Trastuzumab Without Chemotherapy for 12 vs. 24 Weeks in Patients with HER2-positive Breast Cancer.

Rimawi MF, Niravath P, Wang T, Rexer BN, Forero A, Wolff AC, Nanda R, Storniolo AM, Krop I, Goetz MP, Nangia JR, Jiralerspong S, Pavlick A, Veeraraghavan J, De Angelis C, Gutierrez C, Schiff R, Hilsenbeck SG, Osborne CK.

Clin Cancer Res. 2019 Oct 29. pii: clincanres.0851.2019. doi: 10.1158/1078-0432.CCR-19-0851. [Epub ahead of print]


Randomized controlled trial of high-dose versus standard-dose vitamin D3 for prevention of aromatase inhibitor-induced arthralgia.

Niravath P, Hilsenbeck SG, Wang T, Jiralerspong S, Nangia J, Pavlick A, Ademuyiwa F, Frith A, Ma C, Park H, Rigden C, Suresh R, Ellis M, Kent Osborne C, Rimawi MF.

Breast Cancer Res Treat. 2019 Sep;177(2):427-435. doi: 10.1007/s10549-019-05319-4. Epub 2019 Jun 19.


Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival.

Purwaha P, Gu F, Piyarathna DWB, Rajendiran T, Ravindran A, Omilian AR, Jiralerspong S, Das G, Morrison C, Ambrosone C, Coarfa C, Putluri N, Sreekumar A.

Metabolites. 2018 Jul 13;8(3). pii: E41. doi: 10.3390/metabo8030041.


Obesity and Breast Cancer Prognosis: Evidence, Challenges, and Opportunities.

Jiralerspong S, Goodwin PJ.

J Clin Oncol. 2016 Dec 10;34(35):4203-4216. Epub 2016 Nov 7. Review.


Metformin in breast cancer - an evolving mystery.

Camacho L, Dasgupta A, Jiralerspong S.

Breast Cancer Res. 2015 Jun 26;17:88. doi: 10.1186/s13058-015-0598-8.


Obesity, diabetes, and survival outcomes in a large cohort of early-stage breast cancer patients.

Jiralerspong S, Kim ES, Dong W, Feng L, Hortobagyi GN, Giordano SH.

Ann Oncol. 2013 Oct;24(10):2506-14. doi: 10.1093/annonc/mdt224. Epub 2013 Jun 21.


Using whole-exome sequencing to identify inherited causes of autism.

Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, LeClair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA.

Neuron. 2013 Jan 23;77(2):259-73. doi: 10.1016/j.neuron.2012.11.002.


A founder mutation in the PEX6 gene is responsible for increased incidence of Zellweger syndrome in a French Canadian population.

Levesque S, Morin C, Guay SP, Villeneuve J, Marquis P, Yik WY, Jiralerspong S, Bouchard L, Steinberg S, Hacia JG, Dewar K, Braverman NE.

BMC Med Genet. 2012 Aug 15;13:72. doi: 10.1186/1471-2350-13-72.


Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.

Itzkovitz B, Jiralerspong S, Nimmo G, Loscalzo M, Horovitz DD, Snowden A, Moser A, Steinberg S, Braverman N.

Hum Mutat. 2012 Jan;33(1):189-97. doi: 10.1002/humu.21623. Epub 2011 Oct 31.


Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds.

Zhang R, Chen L, Jiralerspong S, Snowden A, Steinberg S, Braverman N.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5569-74. doi: 10.1073/pnas.0914960107. Epub 2010 Mar 8.


Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme.

Qi Y, Spong MC, Nam K, Banerjee A, Jiralerspong S, Karplus M, Verdine GL.

Nature. 2009 Dec 10;462(7274):762-6. doi: 10.1038/nature08561.


Expanding the arsenal: metformin for the treatment of triple-negative breast cancer?

Jiralerspong S, Gonzalez-Angulo AM, Hung MC.

Cell Cycle. 2009 Sep 1;8(17):2681. Epub 2009 Sep 1. No abstract available.


Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer.

Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung MC, Hortobagyi GN, Gonzalez-Angulo AM.

J Clin Oncol. 2009 Jul 10;27(20):3297-302. doi: 10.1200/JCO.2009.19.6410. Epub 2009 Jun 1.


The crystal structure and dimerization interface of GADD45gamma.

Schrag JD, Jiralerspong S, Banville M, Jaramillo ML, O'Connor-McCourt MD.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6566-71. doi: 10.1073/pnas.0800086105. Epub 2008 Apr 29.


Manganese superoxide dismutase induction by iron is impaired in Friedreich ataxia cells.

Jiralerspong S, Ge B, Hudson TJ, Pandolfo M.

FEBS Lett. 2001 Nov 30;509(1):101-5.


Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase.

Jiralerspong S, Rangaswamy V, Bender CL, Parry RJ.

Gene. 2001 May 30;270(1-2):191-200.


Knock-out of the cyaY gene in Escherichia coli does not affect cellular iron content and sensitivity to oxidants.

Li DS, Ohshima K, Jiralerspong S, Bojanowski MW, Pandolfo M.

FEBS Lett. 1999 Jul 30;456(1):13-6.


Biosynthesis of the Pseudomonas polyketide coronafacic acid requires monofunctional and multifunctional polyketide synthase proteins.

Rangaswamy V, Jiralerspong S, Parry R, Bender CL.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15469-74.


Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes.

Campuzano V, Montermini L, Lutz Y, Cova L, Hindelang C, Jiralerspong S, Trottier Y, Kish SJ, Faucheux B, Trouillas P, Authier FJ, Dürr A, Mandel JL, Vescovi A, Pandolfo M, Koenig M.

Hum Mol Genet. 1997 Oct;6(11):1771-80.


Somatic mosaicism for Friedreich's ataxia GAA triplet repeat expansions in the central nervous system.

Montermini L, Kish SJ, Jiralerspong S, Lamarche JB, Pandolfo M.

Neurology. 1997 Aug;49(2):606-10.


Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin.

Babcock M, de Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Montermini L, Pandolfo M, Kaplan J.

Science. 1997 Jun 13;276(5319):1709-12.


Frataxin shows developmentally regulated tissue-specific expression in the mouse embryo.

Jiralerspong S, Liu Y, Montermini L, Stifani S, Pandolfo M.

Neurobiol Dis. 1997;4(2):103-13.


Regulation of the hypoxanthine phosphoribosyltransferase gene: in vitro and in vivo approaches.

Jiralerspong S, Patel PI.

Proc Soc Exp Biol Med. 1996 Jun;212(2):116-27. Review.


Haploinsufficiency of cytosolic serine hydroxymethyltransferase in the Smith-Magenis syndrome.

Elsea SH, Juyal RC, Jiralerspong S, Finucane BM, Pandolfo M, Greenberg F, Baldini A, Stover P, Patel PI.

Am J Hum Genet. 1995 Dec;57(6):1342-50.


The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients.

Zhao Z, Lee CC, Jiralerspong S, Juyal RC, Lu F, Baldini A, Greenberg F, Caskey CT, Patel PI.

Hum Mol Genet. 1995 Apr;4(4):589-97.


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