Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 82

1.

Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships.

Park H, Jin UH, Orr AA, Echegaray SP, Davidson LA, Allred CD, Chapkin R, Jayaraman A, Lee K, Tamamis P, Safe SH.

Chem Res Toxicol. 2019 Oct 17. doi: 10.1021/acs.chemrestox.9b00352. [Epub ahead of print]

PMID:
31621310
2.

The aryl hydrocarbon receptor is a tumor suppressor-like gene in glioblastoma.

Jin UH, Karki K, Cheng Y, Michelhaugh SK, Mittal S, Safe S.

J Biol Chem. 2019 Jul 19;294(29):11342-11353. doi: 10.1074/jbc.RA119.008882. Epub 2019 Jun 6.

PMID:
31171720
3.

Inhibition of pancreatic cancer Panc1 cell migration by omeprazole is dependent on aryl hydrocarbon receptor activation of JNK.

Jin UH, Karki K, Kim SB, Safe S.

Biochem Biophys Res Commun. 2018 Jun 27;501(3):751-757. doi: 10.1016/j.bbrc.2018.05.061.

4.

Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids.

Jin UH, Park H, Li X, Davidson LA, Allred C, Patil B, Jayaprakasha G, Orr AA, Mao L, Chapkin RS, Jayaraman A, Tamamis P, Safe S.

Toxicol Sci. 2018 Jul 1;164(1):205-217. doi: 10.1093/toxsci/kfy075.

5.

Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer.

Cheng Y, Imanirad P, Jutooru I, Hedrick E, Jin UH, Rodrigues Hoffman A, Leal de Araujo J, Morpurgo B, Golovko A, Safe S.

PLoS One. 2018 Feb 1;13(2):e0192264. doi: 10.1371/journal.pone.0192264. eCollection 2018.

6.

Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells.

Jin UH, Cheng Y, Park H, Davidson LA, Callaway ES, Chapkin RS, Jayaraman A, Asante A, Allred C, Weaver EA, Safe S.

Sci Rep. 2017 Aug 31;7(1):10163. doi: 10.1038/s41598-017-10824-x.

7.

Erratum to: Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.

Kolluri SK, Jin UH, Safe S.

Arch Toxicol. 2017 Sep;91(9):3209. doi: 10.1007/s00204-017-2026-6. No abstract available.

PMID:
28695231
8.

Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors.

Karki K, Hedrick E, Kasiappan R, Jin UH, Safe S.

Cancer Prev Res (Phila). 2017 Aug;10(8):467-477. doi: 10.1158/1940-6207.CAPR-17-0053. Epub 2017 Jul 3.

9.

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.

Kolluri SK, Jin UH, Safe S.

Arch Toxicol. 2017 Jul;91(7):2497-2513. doi: 10.1007/s00204-017-1981-2. Epub 2017 May 15. Review. Erratum in: Arch Toxicol. 2017 Sep;91(9):3209.

10.

The Aryl Hydrocarbon Receptor (AhR) as a Drug Target for Cancer Chemotherapy.

Safe S, Cheng Y, Jin UH.

Curr Opin Toxicol. 2017 Feb;2:24-29. doi: 10.1016/j.cotox.2017.01.012. Epub 2017 Feb 1.

11.

Bardoxolone Methyl and a Related Triterpenoid Downregulate cMyc Expression in Leukemia Cells.

Jin UH, Cheng Y, Zhou B, Safe S.

Mol Pharmacol. 2017 May;91(5):438-450. doi: 10.1124/mol.116.106245. Epub 2017 Mar 8.

12.

Monosialyl Ganglioside GM3 Decreases Apolipoprotein B-100 Secretion in Liver Cells.

Choi H, Jin UH, Kang SK, Abekura F, Park JY, Kwon KM, Suh SJ, Cho SH, Ha KT, Lee YC, Chung TW, Kim CH.

J Cell Biochem. 2017 Aug;118(8):2168-2181. doi: 10.1002/jcb.25860. Epub 2017 Apr 25.

PMID:
28019668
13.

Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling.

Cheng Y, Jin UH, Davidson LA, Chapkin RS, Jayaraman A, Tamamis P, Orr A, Allred C, Denison MS, Soshilov A, Weaver E, Safe S.

Toxicol Sci. 2017 Feb;155(2):458-473. doi: 10.1093/toxsci/kfw230. Epub 2016 Nov 11.

14.

Housekeeping promoter 5'pcmah-2 of pig CMP-N-acetylneuraminic acid hydroxylase gene for NeuGc expression.

Song KH, Kwak CH, Jin UH, Ha SH, Park JY, Abekura F, Chang YC, Cho SH, Lee K, Chung TW, Ha KT, Lee YC, Kim CH.

Glycoconj J. 2016 Oct;33(5):779-88. doi: 10.1007/s10719-016-9671-5. Epub 2016 May 17.

PMID:
27188588
15.

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.

Hedrick E, Cheng Y, Jin UH, Kim K, Safe S.

Oncotarget. 2016 Apr 19;7(16):22245-56. doi: 10.18632/oncotarget.7925.

16.

Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC.

Gandhy SU, Imanirad P, Jin UH, Nair V, Hedrick E, Cheng Y, Corton JC, Kim K, Safe S.

Oncotarget. 2015 Sep 22;6(28):26359-72. doi: 10.18632/oncotarget.4560.

17.

Characterization and Biological Potency of Mono- to Tetra-Halogenated Carbazoles.

Riddell N, Jin UH, Safe S, Cheng Y, Chittim B, Konstantinov A, Parette R, Pena-Abaurrea M, Reiner EJ, Poirier D, Stefanac T, McAlees AJ, McCrindle R.

Environ Sci Technol. 2015 Sep 1;49(17):10658-66. doi: 10.1021/acs.est.5b02751. Epub 2015 Aug 13.

PMID:
26226543
18.

Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma.

Hedrick E, Lee SO, Kim G, Abdelrahim M, Jin UH, Safe S, Abudayyeh A.

PLoS One. 2015 Jun 2;10(6):e0128308. doi: 10.1371/journal.pone.0128308. eCollection 2015.

19.

Nuclear receptor 4A (NR4A) family - orphans no more.

Safe S, Jin UH, Morpurgo B, Abudayyeh A, Singh M, Tjalkens RB.

J Steroid Biochem Mol Biol. 2016 Mar;157:48-60. doi: 10.1016/j.jsbmb.2015.04.016. Epub 2015 Apr 23.

20.

Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes.

Cheng Y, Jin UH, Allred CD, Jayaraman A, Chapkin RS, Safe S.

Drug Metab Dispos. 2015 Oct;43(10):1536-43. doi: 10.1124/dmd.115.063677. Epub 2015 Apr 14.

21.

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway.

Jin UH, Kim SB, Safe S.

Chem Res Toxicol. 2015 May 18;28(5):907-18. doi: 10.1021/tx5005198. Epub 2015 Apr 9.

22.

The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis.

Yang WS, Chadalapaka G, Cho SG, Lee SO, Jin UH, Jutooru I, Choi K, Leung YK, Ho SM, Safe S, Kim K.

Neoplasia. 2014 Dec;16(12):1059-69. doi: 10.1016/j.neo.2014.09.011.

23.

Hepatitis B virus X protein specially regulates the sialyl lewis a synthesis among glycosylation events for metastasis.

Chung TW, Kim SJ, Choi HJ, Song KH, Jin UH, Yu DY, Seong JK, Kim JG, Kim KJ, Ko JH, Ha KT, Lee YC, Kim CH.

Mol Cancer. 2014 Sep 25;13:222. doi: 10.1186/1476-4598-13-222.

24.

Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.

Lee SO, Li X, Hedrick E, Jin UH, Tjalkens RB, Backos DS, Li L, Zhang Y, Wu Q, Safe S.

Mol Endocrinol. 2014 Oct;28(10):1729-39. doi: 10.1210/me.2014-1102. Epub 2014 Aug 6.

25.

The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis.

Jin UH, Lee SO, Pfent C, Safe S.

BMC Cancer. 2014 Jul 9;14:498. doi: 10.1186/1471-2407-14-498.

26.

Ganglioside GM3 is required for caffeic acid phenethyl ester-induced megakaryocytic differentiation of human chronic myelogenous leukemia K562 cells.

Jin UH, Chung TW, Song KH, Kwak CH, Choi HJ, Ha KT, Chang YC, Lee YC, Kim CH.

Biochem Cell Biol. 2014 Aug;92(4):243-9. doi: 10.1139/bcb-2014-0015. Epub 2014 May 13.

PMID:
24934090
27.

The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells.

Chung TW, Choi HJ, Kim SJ, Kwak CH, Song KH, Jin UH, Chang YC, Chang HW, Lee YC, Ha KT, Kim CH.

PLoS One. 2014 May 14;9(5):e92786. doi: 10.1371/journal.pone.0092786. eCollection 2014.

28.

Mechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agents.

Jutooru I, Guthrie AS, Chadalapaka G, Pathi S, Kim K, Burghardt R, Jin UH, Safe S.

Mol Cell Biol. 2014 Jul;34(13):2382-95. doi: 10.1128/MCB.01602-13. Epub 2014 Apr 14.

29.

Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities.

Jin UH, Lee SO, Sridharan G, Lee K, Davidson LA, Jayaraman A, Chapkin RS, Alaniz R, Safe S.

Mol Pharmacol. 2014 May;85(5):777-88. doi: 10.1124/mol.113.091165. Epub 2014 Feb 21.

30.

The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.

Lee SO, Jin UH, Kang JH, Kim SB, Guthrie AS, Sreevalsan S, Lee JS, Safe S.

Mol Cancer Res. 2014 Apr;12(4):527-538. doi: 10.1158/1541-7786.MCR-13-0567. Epub 2014 Feb 10.

31.

Minireview: role of orphan nuclear receptors in cancer and potential as drug targets.

Safe S, Jin UH, Hedrick E, Reeder A, Lee SO.

Mol Endocrinol. 2014 Feb;28(2):157-72. doi: 10.1210/me.2013-1291. Epub 2013 Dec 2. Review.

32.

Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation.

Kim SJ, Chung TW, Choi HJ, Jin UH, Ha KT, Lee YC, Kim CH.

Int J Biochem Cell Biol. 2014 Jan;46:32-8. doi: 10.1016/j.biocel.2013.09.015. Epub 2013 Oct 9.

PMID:
24120649
33.

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target.

Safe S, Lee SO, Jin UH.

Toxicol Sci. 2013 Sep;135(1):1-16. doi: 10.1093/toxsci/kft128. Epub 2013 Jun 14. Review.

34.

Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells.

Jin UH, Lee SO, Safe S.

J Pharmacol Exp Ther. 2012 Nov;343(2):333-41. doi: 10.1124/jpet.112.195339. Epub 2012 Aug 9.

35.

Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters.

Kim K, Chadalapaka G, Pathi SS, Jin UH, Lee JS, Park YY, Cho SG, Chintharlapalli S, Safe S.

Mol Cancer Ther. 2012 Sep;11(9):1852-62. doi: 10.1158/1535-7163.MCT-12-0181. Epub 2012 Jun 29.

36.

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.

Lee SO, Andey T, Jin UH, Kim K, Singh M, Safe S.

Oncogene. 2012 Jul 5;31(27):3265-76. doi: 10.1038/onc.2011.504. Epub 2011 Nov 14. Erratum in: Oncogene. 2012 Jul 5;31(27):3310. Sachdeva, M [corrected to Singh, M].

37.

Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells.

Zhang S, Kim K, Jin UH, Pfent C, Cao H, Amendt B, Liu X, Wilson-Robles H, Safe S.

Mol Cancer Ther. 2012 Jan;11(1):108-18. doi: 10.1158/1535-7163.MCT-11-0548. Epub 2011 Oct 27.

38.

Inhibition of pituitary tumor-transforming gene-1 in thyroid cancer cells by drugs that decrease specificity proteins.

Chintharlapalli S, Papineni S, Lee SO, Lei P, Jin UH, Sherman SI, Santarpia L, Safe S.

Mol Carcinog. 2011 Sep;50(9):655-67. doi: 10.1002/mc.20738. Epub 2011 Jan 25.

39.

Molecular characterization of pig alpha2,3-Gal-beta1,3-GalNAc-alpha2,6-sialyltransferase (pST6GalNAc IV) gene specific for Neu5Acalpha2-3Galbeta1-3GalNAc trisaccharide structure.

Ko HK, Song KH, Jin UH, Seong HH, Chang YC, Kim NH, Kim DS, Lee YC, Kim CH.

Glycoconj J. 2010 Apr;27(3):367-74. doi: 10.1007/s10719-010-9284-3. Epub 2010 Mar 22.

PMID:
20306343
40.

Cloning and functional characterization of pig CMP-N-acetylneuraminic acid hydroxylase for the synthesis of N-glycolylneuraminic acid as the xenoantigenic determinant in pig-human xenotransplantation.

Song KH, Kang YJ, Jin UH, Park YI, Kim SM, Seong HH, Hwang S, Yang BS, Im GS, Min KS, Kim JH, Chang YC, Kim NH, Lee YC, Kim CH.

Biochem J. 2010 Mar 15;427(1):179-88. doi: 10.1042/BJ20090835.

PMID:
20047559
41.

Deoxypodophyllotoxin, flavolignan, from Anthriscus sylvestris Hoffm. inhibits migration and MMP-9 via MAPK pathways in TNF-alpha-induced HASMC.

Suh SJ, Kim JR, Jin UH, Choi HS, Chang YC, Lee YC, Kim SH, Lee IS, Moon TC, Chang HW, Kim CH.

Vascul Pharmacol. 2009 Jul;51(1):13-20. doi: 10.1016/j.vph.2008.10.004. Epub 2008 Oct 31.

PMID:
19013539
42.

Inhibition of microsomal triglyceride transfer protein expression and atherogenic risk factor apolipoprotein B100 secretion by tanshinone IIA in HepG2 cells.

Kang YJ, Jin UH, Chang HW, Son JK, Lee SH, Son KH, Chang YC, Lee YC, Kim CH.

Phytother Res. 2008 Dec;22(12):1640-5. doi: 10.1002/ptr.2542.

PMID:
18830968
43.

Antiproliferative effect of Scutellaria barbata D. Don. on cultured human uterine leiomyoma cells by down-regulation of the expression of Bcl-2 protein.

Kim KW, Jin UH, Kim DI, Lee TK, Kim MS, Oh MJ, Kim MS, Kwon DY, Lee YC, Kim CH.

Phytother Res. 2008 May;22(5):583-90. doi: 10.1002/ptr.1996.

PMID:
18444248
44.

Inhibition of mouse osteoblast proliferation and prostaglandin E2 synthesis by Ulmus davidiana Planch (Ulmaceae).

Jin UH, Suh SJ, Park SD, Kim KS, Kwon DY, Kim CH.

Food Chem Toxicol. 2008 Jun;46(6):2135-42. doi: 10.1016/j.fct.2008.02.011. Epub 2008 Feb 15.

PMID:
18378057
45.

Membrane type sialidase inhibits the megakaryocytic differentiation of human leukemia K562 cells.

Jin UH, Ha KT, Kim KW, Chang YC, Lee YC, Ko JH, Kim CH.

Biochim Biophys Acta. 2008 May;1780(5):757-63. doi: 10.1016/j.bbagen.2008.01.019. Epub 2008 Feb 20.

PMID:
18339327
46.

Inhibition of Ulmus davidiana Planch (Ulmaceae) on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.

Kim KW, Park JS, Kim KS, Jin UH, Kim JK, Suh SJ, Kim CH.

Phytother Res. 2008 Apr;22(4):511-7. doi: 10.1002/ptr.2366.

PMID:
18338784
47.

Caffeic acid phenethyl ester induces mitochondria-mediated apoptosis in human myeloid leukemia U937 cells.

Jin UH, Song KH, Motomura M, Suzuki I, Gu YH, Kang YJ, Moon TC, Kim CH.

Mol Cell Biochem. 2008 Mar;310(1-2):43-8. Epub 2007 Nov 30.

PMID:
18060475
48.

Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle cell migration and MMP-9 activity through AKT signaling pathway.

Jin UH, Suh SJ, Chang HW, Son JK, Lee SH, Son KH, Chang YC, Kim CH.

J Cell Biochem. 2008 May 1;104(1):15-26.

PMID:
17979138
49.
50.

Supplemental Content

Support Center