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FGF21 gene therapy as treatment for obesity and insulin resistance.

Jimenez V, Jambrina C, Casana E, Sacristan V, Muñoz S, Darriba S, Rodó J, Mallol C, Garcia M, León X, Marcó S, Ribera A, Elias I, Casellas A, Grass I, Elias G, Ferré T, Motas S, Franckhauser S, Mulero F, Navarro M, Haurigot V, Ruberte J, Bosch F.

EMBO Mol Med. 2018 Jul 9. pii: e8791. doi: 10.15252/emmm.201708791. [Epub ahead of print]


Erosions and vesicles following the lines of Blaschko in a neonate.

Escudero-Góngora MDM, Jiménez V, Martín-Santiago A.

Pediatr Dermatol. 2018 Jul;35(4):519-520. doi: 10.1111/pde.13472. No abstract available.


Factor Xa inhibition and sPESI failure in intermediate-high-risk pulmonary embolism.

Trevino AR, Perez L, Jerjes-Sanchez C, Rodriguez D, Panneflek J, Ortiz-Ledesma C, Nevarez F, Jimenez V, Valdes F, de Obeso E.

Am J Emerg Med. 2018 Jun 22. pii: S0735-6757(18)30533-3. doi: 10.1016/j.ajem.2018.06.054. [Epub ahead of print]


Specialized proteomic responses and an ancient photoprotection mechanism sustain marine green algal growth during phosphate limitation.

Guo J, Wilken S, Jimenez V, Choi CJ, Ansong C, Dannebaum R, Sudek L, Milner DS, Bachy C, Reistetter EN, Elrod VA, Klimov D, Purvine SO, Wei CL, Kunde-Ramamoorthy G, Richards TA, Goodenough U, Smith RD, Callister SJ, Worden AZ.

Nat Microbiol. 2018 Jul;3(7):781-790. doi: 10.1038/s41564-018-0178-7. Epub 2018 Jun 25.


SNARE Complex-associated Proteins in the Lateral Amygdala of Macaca mullatta Following Long-term Ethanol Drinking.

Alexander NJ, Rau AR, Jimenez VA, Daunais JB, Grant KA, McCool BA.

Alcohol Clin Exp Res. 2018 Jun 26. doi: 10.1111/acer.13821. [Epub ahead of print]


Cumulative plasma HIV burden disparities among adults in HIV care: implications for HIV transmission in the era of treatment as prevention.

Hughes AJ, Rector A, Jimenez V, Brock J, Scheer S.

AIDS. 2018 Jun 11. doi: 10.1097/QAD.0000000000001914. [Epub ahead of print]


The use of cardiac CT as a roadmap for resolving coronary stent dislodgement.

Torre-Amione G, de la Pena-Almaguer E, Quintanilla J, Valdes F, Jimenez V, Rodriguez D, Trevino A, Perez L, Jerjes-Sanchez C.

Arch Cardiol Mex. 2018 May 11. pii: S1405-9940(18)30036-3. doi: 10.1016/j.acmx.2018.03.006. [Epub ahead of print] No abstract available.


Giant coronary ectasia and athlete's heart mimicking an acute coronary syndrome.

Manautou L, Jimenez V, Trevino A, Rodriguez D, Jerjes-Sanchez C.

Arch Cardiol Mex. 2018 Apr 28. pii: S1405-9940(18)30038-7. doi: 10.1016/j.acmx.2018.03.008. [Epub ahead of print] No abstract available.


A QM/MM approach on the structural and stereoelectronic factors governing glycosylation by GTF-SI from Streptococcus mutans.

Jaña GA, Mendoza F, Osorio MI, Alderete JB, Fernandes PA, Ramos MJ, Jiménez VA.

Org Biomol Chem. 2018 Apr 4;16(14):2438-2447. doi: 10.1039/C8OB00284C.


Aggregation-induced emission of [3]cumulenes functionalized with heptagon-containing polyphenylenes.

Jiménez VG, Tapia R, Medel MA, Mariz IFA, Ribeiro T, Blanco V, Cuerva JM, Maçôas E, Campaña AG.

Chem Commun (Camb). 2018 Mar 29;54(27):3359-3362. doi: 10.1039/c8cc00386f.


HPLC-DAD-APCI/ESI-MSn analysis of carotenoids and α-tocopherol in Costa Rican Acrocomia aculeata fruits of varying maturity stages.

Schex R, Lieb VM, Jiménez VM, Esquivel P, Schweiggert RM, Carle R, Steingass CB.

Food Res Int. 2018 Mar;105:645-653. doi: 10.1016/j.foodres.2017.11.041. Epub 2017 Nov 21.


Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] using mixture-based combinatorial libraries.

Tran T, Chiem K, Jani S, Arivett BA, Lin DL, Lad R, Jimenez V, Farone MB, Debevec G, Santos R, Giulianotti M, Pinilla C, Tolmasky ME.

Int J Antimicrob Agents. 2018 May;51(5):752-761. doi: 10.1016/j.ijantimicag.2018.01.019. Epub 2018 Feb 2.


Modulation of lateral and longitudinal interdimeric interactions in microtubule models by Laulimalide and Peloruside A association: A molecular modeling approach on the mechanism of microtubule stabilizing agents.

Zúñiga MA, Alderete JB, Jaña GA, Fernandez PA, Ramos MJ, Jiménez VA.

Chem Biol Drug Des. 2018 May;91(5):1042-1055. doi: 10.1111/cbdd.13168. Epub 2018 Jan 23.


Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol.

Finn DA, Jimenez VA.

Handb Exp Pharmacol. 2017 Dec 15. doi: 10.1007/164_2017_82. [Epub ahead of print]


Effects of binge alcohol exposure on Burkholderia thailandensis-alveolar macrophage interaction.

Jimenez V Jr, Moreno R, Kaufman E, Hornstra H, Settles E, Currie BJ, Keim P, Monroy FP.

Alcohol. 2017 Nov;64:55-63. doi: 10.1016/j.alcohol.2017.04.004. Epub 2017 Aug 19.


Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span.

Derevyanko A, Whittemore K, Schneider RP, Jiménez V, Bosch F, Blasco MA.

Aging Cell. 2017 Dec;16(6):1353-1368. doi: 10.1111/acel.12677. Epub 2017 Sep 24.


C. elegans avoids toxin-producing Streptomyces using a seven transmembrane domain chemosensory receptor.

Tran A, Tang A, O'Loughlin CT, Balistreri A, Chang E, Coto Villa D, Li J, Varshney A, Jimenez V, Pyle J, Tsujimoto B, Wellbrook C, Vargas C, Duong A, Ali N, Matthews SY, Levinson S, Woldemariam S, Khuri S, Bremer M, Eggers DK, L'Etoile N, Miller Conrad LC, VanHoven MK.

Elife. 2017 Sep 5;6. pii: e23770. doi: 10.7554/eLife.23770.


AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

Mallol C, Casana E, Jimenez V, Casellas A, Haurigot V, Jambrina C, Sacristan V, Morró M, Agudo J, Vilà L, Bosch F.

Mol Metab. 2017 May 17;6(7):664-680. doi: 10.1016/j.molmet.2017.05.007. eCollection 2017 Jul.


Understanding factors affecting collaboration between midwives and other health care professionals in a birth center and its affiliated Quebec hospital: a case study.

Behruzi R, Klam S, Dehertog M, Jimenez V, Hatem M.

BMC Pregnancy Childbirth. 2017 Jun 26;17(1):200. doi: 10.1186/s12884-017-1381-x.


Effects of high-intensity interval versus continuous exercise training on post-exercise heart rate recovery in coronary heart-disease patients.

Villelabeitia-Jaureguizar K, Vicente-Campos D, Senen AB, Jiménez VH, Garrido-Lestache MEB, Chicharro JL.

Int J Cardiol. 2017 Oct 1;244:17-23. doi: 10.1016/j.ijcard.2017.06.067. Epub 2017 Jun 17.


Molecular modeling study on the tubulin-binding modes of epothilone derivatives: Insight into the structural basis for epothilones activity.

Jiménez VA, Alderete JB, Navarrete KR.

Chem Biol Drug Des. 2017 Dec;90(6):1247-1259. doi: 10.1111/cbdd.13046. Epub 2017 Jul 18.


Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs.

Jaén ML, Vilà L, Elias I, Jimenez V, Rodó J, Maggioni L, Ruiz-de Gopegui R, Garcia M, Muñoz S, Callejas D, Ayuso E, Ferré T, Grifoll I, Andaluz A, Ruberte J, Haurigot V, Bosch F.

Mol Ther Methods Clin Dev. 2017 Apr 5;6:1-7. doi: 10.1016/j.omtm.2017.03.008. eCollection 2017 Sep 15.


Structural insight into the role of Gln293Met mutation on the Peloruside A/Laulimalide association with αβ-tubulin from molecular dynamics simulations, binding free energy calculations and weak interactions analysis.

Zúñiga MA, Alderete JB, Jaña GA, Jiménez VA.

J Comput Aided Mol Des. 2017 Jul;31(7):643-652. doi: 10.1007/s10822-017-0029-2. Epub 2017 Jun 9.


Acoustic Analysis of Voice and Electroglottography in Patients With Laryngopharyngeal Reflux.

Ramírez DAM, Jiménez VMV, López XH, Ysunza PA.

J Voice. 2018 May;32(3):281-284. doi: 10.1016/j.jvoice.2017.05.009. Epub 2017 Jun 5.


A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.

Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L.

Mol Psychiatry. 2018 Jun;23(6):1466-1473. doi: 10.1038/mp.2017.97. Epub 2017 May 2.


Spillover effects on health outcomes in low- and middle-income countries: a systematic review.

Benjamin-Chung J, Abedin J, Berger D, Clark A, Jimenez V, Konagaya E, Tran D, Arnold BF, Hubbard AE, Luby SP, Miguel E, Colford JM Jr.

Int J Epidemiol. 2017 Aug 1;46(4):1251-1276. doi: 10.1093/ije/dyx039. Review.


Characterization of Mesocarp and Kernel Lipids from Elaeis guineensis Jacq., Elaeis oleifera [Kunth] Cortés, and Their Interspecific Hybrids.

Lieb VM, Kerfers MR, Kronmüller A, Esquivel P, Alvarado A, Jiménez VM, Schmarr HG, Carle R, Schweiggert RM, Steingass CB.

J Agric Food Chem. 2017 May 10;65(18):3617-3626. doi: 10.1021/acs.jafc.7b00604. Epub 2017 May 1.


Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin.

Diaz C, Guzmán J, Jiménez VA, Alderete JB.

Pharm Dev Technol. 2017 Apr 19:1-8. doi: 10.1080/10837450.2017.1315134. [Epub ahead of print]


Studies using macaque monkeys to address excessive alcohol drinking and stress interactions.

Jimenez VA, Grant KA.

Neuropharmacology. 2017 Aug 1;122:127-135. doi: 10.1016/j.neuropharm.2017.03.027. Epub 2017 Mar 24. Review.


Social setting, social rank and HPA axis response in cynomolgus monkeys.

Jimenez VA, Allen DC, McClintick MN, Grant KA.

Psychopharmacology (Berl). 2017 Jun;234(12):1881-1889. doi: 10.1007/s00213-017-4596-7. Epub 2017 Mar 22.


Adaptations in Basal and Hypothalamic-Pituitary-Adrenal-Activated Deoxycorticosterone Responses Following Ethanol Self-administration in Cynomolgus Monkeys.

Jimenez VA, Porcu P, Morrow AL, Grant KA.

Front Endocrinol (Lausanne). 2017 Feb 6;8:19. doi: 10.3389/fendo.2017.00019. eCollection 2017.


Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease.

Stein S, Lemos V, Xu P, Demagny H, Wang X, Ryu D, Jimenez V, Bosch F, Lüscher TF, Oosterveer MH, Schoonjans K.

J Clin Invest. 2017 Feb 1;127(2):583-592. doi: 10.1172/JCI85499. Epub 2017 Jan 17.


Association of Methotrexate with Native and PEGylated PAMAM-G4 Dendrimers: Effect of the PEGylation Degree on the Drug-Loading Capacity and Preferential Binding Sites.

Barraza LF, Jiménez VA, Alderete JB.

J Phys Chem B. 2017 Jan 12;121(1):4-12. doi: 10.1021/acs.jpcb.6b08882. Epub 2016 Dec 27.


Carotenoids and carotenoid esters of orange- and yellow-fleshed mamey sapote (Pouteria sapota (Jacq.) H.E. Moore & Stearn) fruit and their post-prandial absorption in humans.

Chacón-Ordóñez T, Schweiggert RM, Bosy-Westphal A, Jiménez VM, Carle R, Esquivel P.

Food Chem. 2017 Apr 15;221:673-682. doi: 10.1016/j.foodchem.2016.11.120. Epub 2016 Nov 29.


Study on the relationship of genotoxic and oxidative potential of a new mixed chelate copper antitumoral drug, Casiopeina II-gly (Cas II-gly) in Drosophila melanogaster.

Jiménez VE, Pimentel E, Cruces MP, Amaya-Chávez A, Ruiz-Azuara L.

Environ Toxicol Pharmacol. 2016 Dec;48:286-293. doi: 10.1016/j.etap.2016.11.008. Epub 2016 Nov 13.


Binding free energy calculations on E-selectin complexes with sLex oligosaccharide analogs.

Barra PA, Ribeiro AJ, Ramos MJ, Jiménez VA, Alderete JB, Fernandes PA.

Chem Biol Drug Des. 2017 Jan;89(1):114-123. doi: 10.1111/cbdd.12837. Epub 2016 Sep 21.


Reversal of Ethanol-induced Intoxication by a Novel Modulator of Gβγ Protein Potentiation of the Glycine Receptor.

San Martin L, Cerda F, Jin C, Jimenez V, Yevenes GE, Hernandez T, Nova D, Fuentealba J, Aguayo LG, Guzman L.

J Biol Chem. 2016 Sep 2;291(36):18791-8. doi: 10.1074/jbc.M116.740555. Epub 2016 Jul 11.


Intermediate- to high-risk pulmonary embolism with normal B-type natriuretic peptide.

Quintanilla J, Jerjes-Sanchez C, Perez L, Valdes F, Jimenez V, Trevino AR, Rodriguez D.

Am J Emerg Med. 2016 Dec;34(12):2463.e1-2463.e3. doi: 10.1016/j.ajem.2016.05.070. Epub 2016 May 31. No abstract available.


PAMAM-grafted TiO2 nanotubes as novel versatile materials for drug delivery applications.

Torres CC, Campos CH, Diáz C, Jiménez VA, Vidal F, Guzmán L, Alderete JB.

Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:164-71. doi: 10.1016/j.msec.2016.03.104. Epub 2016 Apr 7.


A randomized comparison of novel bioresorbable polymer sirolimus-eluting stent and durable polymer everolimus-eluting stent in patients with acute coronary syndromes: The CENTURY II high risk ACS substudy.

Jiménez VA, Iñiguez A, Baz JA, Valdés M, Ortiz A, Vuilliomenet A, Mainar V, Dudek D, Banai S, Tüller D, Bonnet JL, De Miguel A, Bastos G, Wijns W, Saito S.

Cardiovasc Revasc Med. 2016 Sep;17(6):355-61. doi: 10.1016/j.carrev.2016.04.001. Epub 2016 Apr 19.


Significance of prior percutaneous revascularisation in patients with acute coronary syndromes: insights from the prospective PROSPECT registry.

Iñiguez A, Brener SJ, Jiménez VA, Maehara A, Mintz GS, Xu K, Weisz G, Lansky AJ, De Bruyne B, Serruys PW, Stone GW.

EuroIntervention. 2016 Apr 20;11(13):1468-74. doi: 10.4244/EIJV11I13A285.


Discovery of New E-Selectin Inhibitors by Virtual Screening, Fluorescence Binding Assays, and STD NMR Experiments.

Barra PA, Jiménez VA, Gavin JA, Daranas AH, Alderete JB.

ChemMedChem. 2016 May 6;11(9):1008-14. doi: 10.1002/cmdc.201600058. Epub 2016 Mar 21.


Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques.

Siciliano CA, Calipari ES, Yorgason JT, Lovinger DM, Mateo Y, Jimenez VA, Helms CM, Grant KA, Jones SR.

Psychopharmacology (Berl). 2016 Apr;233(8):1435-43. doi: 10.1007/s00213-016-4239-4. Epub 2016 Feb 19.


Deposition Form and Bioaccessibility of Keto-carotenoids from Mamey Sapote (Pouteria sapota), Red Bell Pepper (Capsicum annuum), and Sockeye Salmon (Oncorhynchus nerka) Filet.

Chacón-Ordóñez T, Esquivel P, Jiménez VM, Carle R, Schweiggert RM.

J Agric Food Chem. 2016 Mar 9;64(9):1989-98. doi: 10.1021/acs.jafc.5b06039. Epub 2016 Mar 1.


Carotenoids, carotenoid esters, and anthocyanins of yellow-, orange-, and red-peeled cashew apples (Anacardium occidentale L.).

Schweiggert RM, Vargas E, Conrad J, Hempel J, Gras CC, Ziegler JU, Mayer A, Jiménez V, Esquivel P, Carle R.

Food Chem. 2016 Jun 1;200:274-82. doi: 10.1016/j.foodchem.2016.01.038. Epub 2016 Jan 11.


mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue.

Albert V, Svensson K, Shimobayashi M, Colombi M, Muñoz S, Jimenez V, Handschin C, Bosch F, Hall MN.

EMBO Mol Med. 2016 Mar 1;8(3):232-46. doi: 10.15252/emmm.201505610.


Abundance and Biogeography of Picoprasinophyte Ecotypes and Other Phytoplankton in the Eastern North Pacific Ocean.

Simmons MP, Sudek S, Monier A, Limardo AJ, Jimenez V, Perle CR, Elrod VA, Pennington JT, Worden AZ.

Appl Environ Microbiol. 2016 Jan 4;82(6):1693-1705. doi: 10.1128/AEM.02730-15.


Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.

Teichenne J, Morró M, Casellas A, Jimenez V, Tellez N, Leger A, Bosch F, Ayuso E.

PLoS One. 2015 Dec 21;10(12):e0145116. doi: 10.1371/journal.pone.0145116. eCollection 2015.


CDK4 is an essential insulin effector in adipocytes.

Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L.

J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14.

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