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Items: 17

1.

Brain derived neutrophic factor (BDNF) coordinates lympho-vascular metastasis through a fibroblast-governed paracrine axis in the tumor microenvironment.

Jiffar T, Yilmaz T, Lee J, Miller Y, Feng L, El-Naggar A, Kupferman ME.

Cancer Cell Microenviron. 2017;4(2). pii: e1566. doi: 10.14800/ccm.1566. Epub 2017 Jul 10.

2.

Human epidermal growth factor receptor 2/neu as a novel therapeutic target in sinonasal undifferentiated carcinoma.

Takahashi Y, Lee J, Pickering C, Bell D, Jiffar TW, Myers JN, Hanna EY, Kupferman ME.

Head Neck. 2016 Apr;38 Suppl 1:E1926-34. doi: 10.1002/hed.24350. Epub 2016 Jan 11.

3.

Coordinated targeting of the EGFR signaling axis by microRNA-27a*.

Wu X, Bhayani MK, Dodge CT, Nicoloso MS, Chen Y, Yan X, Adachi M, Thomas L, Galer CE, Jiffar T, Pickering CR, Kupferman ME, Myers JN, Calin GA, Lai SY.

Oncotarget. 2013 Sep;4(9):1388-98.

4.

Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity.

Chintalgattu V, Rees ML, Culver JC, Goel A, Jiffar T, Zhang J, Dunner K Jr, Pati S, Bankson JA, Pasqualini R, Arap W, Bryan NS, Taegtmeyer H, Langley RR, Yao H, Kupferman ME, Entman ML, Dickinson ME, Khakoo AY.

Sci Transl Med. 2013 May 29;5(187):187ra69. doi: 10.1126/scitranslmed.3005066.

5.

Establishment and characterization of novel cell lines from sinonasal undifferentiated carcinoma.

Takahashi Y, Kupferman ME, Bell D, Jiffar T, Lee JG, Xie TX, Li NW, Zhao M, Frederick MJ, Gelbard A, Myers JN, Hanna EY.

Clin Cancer Res. 2012 Nov 15;18(22):6178-87. doi: 10.1158/1078-0432.CCR-12-1876. Epub 2012 Oct 2.

6.

A novel role for BDNF-TrkB in the regulation of chemotherapy resistance in head and neck squamous cell carcinoma.

Lee J, Jiffar T, Kupferman ME.

PLoS One. 2012;7(1):e30246. doi: 10.1371/journal.pone.0030246. Epub 2012 Jan 20.

7.

KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma.

Jiffar T, Yilmaz T, Lee J, Hanna E, El-Naggar A, Yu D, Myers JN, Kupferman ME.

Oncogene. 2011 Jul 14;30(28):3163-73. doi: 10.1038/onc.2011.39. Epub 2011 Mar 7.

8.

Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells.

Ruvolo PP, Zhou L, Watt JC, Ruvolo VR, Burks JK, Jiffar T, Kornblau S, Konopleva M, Andreeff M.

J Cell Biochem. 2011 Jun;112(6):1696-707. doi: 10.1002/jcb.23090.

9.

Theraputic targeting of Trk supresses tumor proliferation and enhances cisplatin activity in HNSCC.

Yilmaz T, Jiffar T, de la Garza G, Lin H, Milas Z, Takahashi Y, Hanna E, MacIntyre T, Brown JL, Myers JN, Kupferman ME.

Cancer Biol Ther. 2010 Sep 15;10(6):644-53. doi: 10.4161/cbt.10.6.12782. Epub 2010 Sep 23.

10.

TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma.

Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN.

Oncogene. 2010 Apr 8;29(14):2047-59. doi: 10.1038/onc.2009.486. Epub 2010 Jan 18.

11.

Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK.

Nica AF, Tsao CC, Watt JC, Jiffar T, Kurinna S, Jurasz P, Konopleva M, Andreeff M, Radomski MW, Ruvolo PP.

Cell Cycle. 2008 Nov 1;7(21):3362-70. Epub 2008 Nov 2.

12.

Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells.

Tsao CC, Nica AF, Kurinna SM, Jiffar T, Mumby M, Ruvolo PP.

Cell Cycle. 2007 Oct 1;6(19):2377-85. Epub 2007 Jul 12.

PMID:
17700073
13.

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M.

Cancer Cell. 2006 Nov;10(5):375-88.

14.

Protein kinase C delta mediates platelet-induced breast cancer cell invasion.

Alonso-Escolano D, Medina C, Cieslik K, Radomski A, Jurasz P, Santos-Martínez MJ, Jiffar T, Ruvolo P, Radomski MW.

J Pharmacol Exp Ther. 2006 Jul;318(1):373-80. Epub 2006 Apr 14.

PMID:
16617167
15.

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase.

Kurinna SM, Tsao CC, Nica AF, Jiffar T, Ruvolo PP.

Cancer Res. 2004 Nov 1;64(21):7852-6.

16.

PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation.

Jiffar T, Kurinna S, Suck G, Carlson-Bremer D, Ricciardi MR, Konopleva M, Andreeff M, Ruvolo PP.

Leukemia. 2004 Mar;18(3):505-12.

PMID:
14737078
17.

Requirement for SAPK-JNK signaling in the induction of apoptosis by ribosomal stress in REH lymphoid leukemia cells.

Johnson CR, Jiffar T, Fischer UM, Ruvolo PP, Jarvis WD.

Leukemia. 2003 Nov;17(11):2140-8.

PMID:
12970763

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