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Items: 1 to 50 of 155

1.

SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells.

Xu XL, Li Z, Liu A, Fan X, Hu DN, Qi DL, Chitty DW, Jia R, Qui J, Wang JQ, Sharaf J, Zou J, Weiss R, Huang H, Joseph WJ, Ng L, Rosen R, Shen B, Reid MW, Forrest D, Abramson DH, Singer S, Cobrinik D, Jhanwar SC.

Cancer Res. 2017 Dec 15;77(24):6838-6850. doi: 10.1158/0008-5472.CAN-16-3299. Epub 2017 Sep 28.

2.

Genomic instability and proliferation/survival pathways in RB1-deficient malignancies.

Pappas L, Xu XL, Abramson DH, Jhanwar SC.

Adv Biol Regul. 2017 May;64:20-32. doi: 10.1016/j.jbior.2017.01.002. Epub 2017 Feb 8.

PMID:
28242412
3.

Gain of chromosome 1q portends worse prognosis in multiple myeloma despite novel agent-based induction regimens and autologous transplantation.

Shah GL, Landau H, Londono D, Devlin SM, Kosuri S, Lesokhin AM, Lendvai N, Hassoun H, Chung DJ, Koehne G, Jhanwar SC, Landgren O, Levine R, Giralt SA.

Leuk Lymphoma. 2017 Aug;58(8):1823-1831. doi: 10.1080/10428194.2016.1260126. Epub 2017 Jan 12.

4.

NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.

Garcia-Rendueles ME, Ricarte-Filho JC, Untch BR, Landa I, Knauf JA, Voza F, Smith VE, Ganly I, Taylor BS, Persaud Y, Oler G, Fang Y, Jhanwar SC, Viale A, Heguy A, Huberman KH, Giancotti F, Ghossein R, Fagin JA.

Cancer Discov. 2015 Nov;5(11):1178-93. doi: 10.1158/2159-8290.CD-15-0330. Epub 2015 Sep 10. Erratum in: Cancer Discov. 2019 Nov;9(11):1628.

5.

Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview.

Jhanwar SC.

Adv Biol Regul. 2015 May;58:28-37. doi: 10.1016/j.jbior.2014.11.002. Epub 2014 Nov 20. Review.

PMID:
25499150
6.

Rb suppresses human cone-precursor-derived retinoblastoma tumours.

Xu XL, Singh HP, Wang L, Qi DL, Poulos BK, Abramson DH, Jhanwar SC, Cobrinik D.

Nature. 2014 Oct 16;514(7522):385-8. doi: 10.1038/nature13813. Epub 2014 Sep 24.

7.

Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors.

Panageas KS, Reiner AS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Urgoiti GB, Wen PY, Ligon KL, Schiff D, Robins HI, Rocque BG, Chamberlain MC, Mason WP, Weaver SA, Green RM, Kamar FG, Abrey LE, DeAngelis LM, Jhanwar SC, Rosenblum MK, Lassman AB.

Neuro Oncol. 2014 Nov;16(11):1541-6. doi: 10.1093/neuonc/nou083. Epub 2014 Jul 4.

8.

Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.

Dickson MA, Papadopoulos EB, Hedvat CV, Jhanwar SC, Brentjens RJ.

Leuk Res Rep. 2014 May 20;3(2):38-41. doi: 10.1016/j.lrr.2014.04.001. eCollection 2014.

9.

A genome-wide high-resolution array-CGH analysis of cutaneous melanoma and comparison of array-CGH to FISH in diagnostic evaluation.

Wang L, Rao M, Fang Y, Hameed M, Viale A, Busam K, Jhanwar SC.

J Mol Diagn. 2013 Sep;15(5):581-91. doi: 10.1016/j.jmoldx.2013.04.001. Epub 2013 Jun 22.

PMID:
23800576
10.

Initial treatment patterns over time for anaplastic oligodendroglial tumors.

Panageas KS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Roldán Urgoiti GB, Wen PY, Ligon KL, Schiff D, Robins HI, Rocque BG, Chamberlain MC, Mason WP, Weaver SA, Green RM, Kamar FG, Abrey LE, Deangelis LM, Jhanwar SC, Rosenblum MK, Lassman AB.

Neuro Oncol. 2012 Jun;14(6):761-7. doi: 10.1093/neuonc/nos065. Epub 2012 May 31.

11.

The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.

Landau HJ, McNeely SC, Nair JS, Comenzo RL, Asai T, Friedman H, Jhanwar SC, Nimer SD, Schwartz GK.

Mol Cancer Ther. 2012 Aug;11(8):1781-8. doi: 10.1158/1535-7163.MCT-11-0949. Epub 2012 May 31.

12.

Will a peripheral blood (PB) sample yield the same diagnostic and prognostic cytogenetic data as the concomitant bone marrow (BM) in myelodysplasia?

Cherry AM, Slovak ML, Campbell LJ, Chun K, Eclache V, Haase D, Haferlach C, Hildebrandt B, Iqbal AM, Jhanwar SC, Ohyashiki K, Sole F, Vandenberghe P, VanDyke DL, Zhang Y, Dewald GW.

Leuk Res. 2012 Jul;36(7):832-40. doi: 10.1016/j.leukres.2012.03.013. Epub 2012 Apr 25.

PMID:
22537394
13.

IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma.

Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT.

Clin Cancer Res. 2012 May 1;18(9):2490-501. doi: 10.1158/1078-0432.CCR-11-2977. Epub 2012 Mar 13.

14.

Chromothripsis in a Case of TP53-Deficient Chronic Lymphocytic Leukemia.

Pei J, Jhanwar SC, Testa JR.

Leuk Res Rep. 2012 Jan 1;1(1):4-6.

15.

International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.

Lassman AB, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Roldán GB, Wen PY, Ligon KL, Schiff D, Robins HI, Rocque BG, Chamberlain MC, Mason WP, Weaver SA, Green RM, Kamar FG, Abrey LE, DeAngelis LM, Jhanwar SC, Rosenblum MK, Panageas KS.

Neuro Oncol. 2011 Jun;13(6):649-59. doi: 10.1093/neuonc/nor040.

16.

Genetic abnormalities in non-Hodgkin's lymphoma as revealed by conventional and molecular cytogenetics methods of analyses.

Jhanwar SC, Denley RC.

Methods Mol Biol. 2011;730:131-48. doi: 10.1007/978-1-61779-074-4_10.

PMID:
21431639
17.

MET expression and amplification in patients with localized gastric cancer.

Janjigian YY, Tang LH, Coit DG, Kelsen DP, Francone TD, Weiser MR, Jhanwar SC, Shah MA.

Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):1021-7. doi: 10.1158/1055-9965.EPI-10-1080. Epub 2011 Mar 10.

18.

ETV6-ABL1-positive "chronic myeloid leukemia": clinical and molecular response to tyrosine kinase inhibition.

Perna F, Abdel-Wahab O, Levine RL, Jhanwar SC, Imada K, Nimer SD.

Haematologica. 2011 Feb;96(2):342-3. doi: 10.3324/haematol.2010.036673. Epub 2010 Dec 29. No abstract available.

19.

Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.

Butrynski JE, D'Adamo DR, Hornick JL, Dal Cin P, Antonescu CR, Jhanwar SC, Ladanyi M, Capelletti M, Rodig SJ, Ramaiya N, Kwak EL, Clark JW, Wilner KD, Christensen JG, Jänne PA, Maki RG, Demetri GD, Shapiro GI.

N Engl J Med. 2010 Oct 28;363(18):1727-33. doi: 10.1056/NEJMoa1007056.

20.

Genomic and biological characterization of exon 4 KRAS mutations in human cancer.

Janakiraman M, Vakiani E, Zeng Z, Pratilas CA, Taylor BS, Chitale D, Halilovic E, Wilson M, Huberman K, Ricarte Filho JC, Persaud Y, Levine DA, Fagin JA, Jhanwar SC, Mariadason JM, Lash A, Ladanyi M, Saltz LB, Heguy A, Paty PB, Solit DB.

Cancer Res. 2010 Jul 15;70(14):5901-11. doi: 10.1158/0008-5472.CAN-10-0192. Epub 2010 Jun 22.

21.

Tumor-associated retinal astrocytes promote retinoblastoma cell proliferation through production of IGFBP-5.

Xu XL, Lee TC, Offor N, Cheng C, Liu A, Fang Y, Jhanwar SC, Abramson DH, Cobrinik D.

Am J Pathol. 2010 Jul;177(1):424-35. doi: 10.2353/ajpath.2010.090512. Epub 2010 May 27.

22.

Distinction of conjunctival melanocytic nevi from melanomas by fluorescence in situ hybridization.

Busam KJ, Fang Y, Jhanwar SC, Pulitzer MP, Marr B, Abramson DH.

J Cutan Pathol. 2010 Feb;37(2):196-203. doi: 10.1111/j.1600-0560.2009.01488.x.

PMID:
20100177
23.

The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival.

Cheung M, Pei J, Pei Y, Jhanwar SC, Pass HI, Testa JR.

Oncogene. 2010 Mar 18;29(11):1633-40. doi: 10.1038/onc.2009.455. Epub 2009 Dec 14.

24.

Feasibility of ex vivo FDG PET of the colon.

Gollub MJ, Akhurst TJ, Williamson MJ, Shia J, Humm JL, Wong WD, Paty PB, Guillem JG, Weiser MR, Temple LK, Dauer LT, Jhanwar SC, Kronman RE, Montalvo CV, Miller AR, Larson SM, Margulis AR.

Radiology. 2009 Jul;252(1):232-9. doi: 10.1148/radiol.2522081864.

PMID:
19561258
25.

Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling.

Xu XL, Fang Y, Lee TC, Forrest D, Gregory-Evans C, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D.

Cell. 2009 Jun 12;137(6):1018-31. doi: 10.1016/j.cell.2009.03.051.

26.

Persistence of expression of the TMPRSS2:ERG fusion gene after pre-surgery androgen ablation may be associated with early prostate specific antigen relapse of prostate cancer: preliminary results.

Bonaccorsi L, Nesi G, Nuti F, Paglierani M, Krausz C, Masieri L, Serni S, Proietti-Pannunzi L, Fang Y, Jhanwar SC, Orlando C, Carini M, Forti G, Baldi E, Luzzatto L.

J Endocrinol Invest. 2009 Jul;32(7):590-6. doi: 10.1007/BF03346514. Epub 2009 May 5.

PMID:
19494719
27.
28.

Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma.

Kushner BH, Kramer K, Modak S, Qin LX, Yataghena K, Jhanwar SC, Cheung NK.

Pediatr Blood Cancer. 2009 Jul;53(1):17-22. doi: 10.1002/pbc.21931.

29.

Transplantation in remission improves the disease-free survival of patients with advanced myelodysplastic syndromes treated with myeloablative T cell-depleted stem cell transplants from HLA-identical siblings.

Castro-Malaspina H, Jabubowski AA, Papadopoulos EB, Boulad F, Young JW, Kernan NA, Perales MA, Small TN, Hsu K, Chiu M, Heller G, Collins NH, Jhanwar SC, van den Brink M, Nimer SD, O'Reilly RJ.

Biol Blood Marrow Transplant. 2008 Apr;14(4):458-68. doi: 10.1016/j.bbmt.2008.02.006.

30.

A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.

Tan Y, Timakhov RA, Rao M, Altomare DA, Xu J, Liu Z, Gao Q, Jhanwar SC, Di Cristofano A, Wiest DL, Knepper JE, Testa JR.

Cancer Res. 2008 Mar 1;68(5):1296-302. doi: 10.1158/0008-5472.CAN-07-3218.

31.

Teratocarcinosarcoma of the nasal cavity and paranasal sinuses: report of 3 cases with assessment for chromosome 12p status.

Salem F, Rosenblum MK, Jhanwar SC, Kancherla P, Ghossein RA, Carlson DL.

Hum Pathol. 2008 Apr;39(4):605-9. doi: 10.1016/j.humpath.2007.09.002. Epub 2008 Mar 4.

PMID:
18284932
32.

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.

Robinson BW, Cheung NK, Kolaris CP, Jhanwar SC, Choi JK, Osheroff N, Felix CA.

Blood. 2008 Apr 1;111(7):3802-12. doi: 10.1182/blood-2007-07-096065. Epub 2008 Jan 14.

33.

Molecular cytogenetic analysis of follicular lymphoma (FL) provides detailed characterization of chromosomal instability associated with the t(14;18)(q32;q21) positive and negative subsets and histologic progression.

Nanjangud G, Rao PH, Teruya-Feldstein J, Donnelly G, Qin J, Mehra S, Jhanwar SC, Zelenetz AD, Chaganti RS.

Cytogenet Genome Res. 2007;118(2-4):337-44.

PMID:
18000388
34.

Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.

Poulikakos PI, Xiao GH, Gallagher R, Jablonski S, Jhanwar SC, Testa JR.

Oncogene. 2006 Sep 28;25(44):5960-8. Epub 2006 May 1.

PMID:
16652148
35.

A mouse model recapitulating molecular features of human mesothelioma.

Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR.

Cancer Res. 2005 Sep 15;65(18):8090-5.

36.

Identification of MYCN gene amplification in neuroblastoma using chromogenic in situ hybridization (CISH): an alternative and practical method.

Bhargava R, Oppenheimer O, Gerald W, Jhanwar SC, Chen B.

Diagn Mol Pathol. 2005 Jun;14(2):72-6.

PMID:
15905689
37.

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.

Altomare DA, You H, Xiao GH, Ramos-Nino ME, Skele KL, De Rienzo A, Jhanwar SC, Mossman BT, Kane AB, Testa JR.

Oncogene. 2005 Sep 8;24(40):6080-9.

PMID:
15897870
38.

Will the new cytogenetics replace the old cytogenetics?

Salman M, Jhanwar SC, Ostrer H.

Clin Genet. 2004 Oct;66(4):265-75. Review.

PMID:
15355426
39.

Growth inhibition and induction of apoptosis in mesothelioma cells by selenium and dependence on selenoprotein SEP15 genotype.

Apostolou S, Klein JO, Mitsuuchi Y, Shetler JN, Poulikakos PI, Jhanwar SC, Kruger WD, Testa JR.

Oncogene. 2004 Jun 24;23(29):5032-40.

PMID:
15107826
40.

Genomic Alterations in Gastrointestinal Stromal Tumors as Revealed by Conventional and Array-based Comparative Genomic Hybridization.

Granitto SR, Kolachana P, Antonescu CR, Johnson RC, Dematteo RP, Jhanwar SC.

Cancer Genomics Proteomics. 2004 Mar-Apr;1(2):105-116. Epub 2004 Mar 1.

41.

Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification.

Iwamoto M, Banerjee D, Menon LG, Jurkiewicz A, Rao PH, Kemeny NE, Fong Y, Jhanwar SC, Gorlick R, Bertino JR.

Cancer Biol Ther. 2004 Apr;3(4):395-9. Epub 2004 Apr 29.

PMID:
14726656
42.

Molecular cytogenetic analysis of genomic instability at the 1q12-22 chromosomal site in B-cell non-Hodgkin lymphoma.

Itoyama T, Nanjungud G, Chen W, Dyomin VG, Teruya-Feldstein J, Jhanwar SC, Zelenetz AD, Chaganti RS.

Genes Chromosomes Cancer. 2002 Dec;35(4):318-28.

PMID:
12378526
43.

Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop.

Andersen MK, Larson RA, Mauritzson N, Schnittger S, Jhanwar SC, Pedersen-Bjergaard J.

Genes Chromosomes Cancer. 2002 Apr;33(4):395-400.

PMID:
11921273
44.

Spectral karyotyping identifies new rearrangements, translocations, and clinical associations in diffuse large B-cell lymphoma.

Nanjangud G, Rao PH, Hegde A, Teruya-Feldstein J, Donnelly G, Qin J, Jhanwar SC, Zelenetz AD, Chaganti RS.

Blood. 2002 Apr 1;99(7):2554-61.

PMID:
11895793
45.

SV40 infection induces telomerase activity in human mesothelial cells.

Foddis R, De Rienzo A, Broccoli D, Bocchetta M, Stekala E, Rizzo P, Tosolini A, Grobelny JV, Jhanwar SC, Pass HI, Testa JR, Carbone M.

Oncogene. 2002 Feb 21;21(9):1434-42.

46.

Deregulation of FCGR2B expression by 1q21 rearrangements in follicular lymphomas.

Chen W, Palanisamy N, Schmidt H, Teruya-Feldstein J, Jhanwar SC, Zelenetz AD, Houldsworth J, Chaganti RS.

Oncogene. 2001 Nov 15;20(52):7686-93.

47.

Loss of heterozygosity analysis defines a 3-cM region of 15q commonly deleted in human malignant mesothelioma.

De Rienzo A, Balsara BR, Apostolou S, Jhanwar SC, Testa JR.

Oncogene. 2001 Sep 27;20(43):6245-9.

48.

Characterization and drug sensitivity of four newly established colon adenocarcinoma cell lines to antifolate inhibitors of thymidylate synthase.

Longo GS, Izzo J, Gorlick R, Banerjee D, Jhanwar SC, Bertino JR.

Oncol Res. 2001;12(8):309-14.

PMID:
11589301
49.

Frequent gain of chromosome 19 in megakaryoblastic leukemias detected by comparative genomic hybridization.

Alvarez S, MacGrogan D, Calasanz MJ, Nimer SD, Jhanwar SC.

Genes Chromosomes Cancer. 2001 Nov;32(3):285-93.

PMID:
11579469
50.

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