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Items: 1 to 50 of 99

1.

Effect of a scaled-up neonatal resuscitation quality improvement package on intrapartum-related mortality in Nepal: A stepped-wedge cluster randomized controlled trial.

Kc A, Ewald U, Basnet O, Gurung A, Pyakuryal SN, Jha BK, Bergström A, Eriksson L, Paudel P, Karki S, Gajurel S, Brunell O, Wrammert J, Litorp H, Målqvist M.

PLoS Med. 2019 Sep 9;16(9):e1002900. doi: 10.1371/journal.pmed.1002900. eCollection 2019 Sep.

2.

Genomics of therapy-related myeloid neoplasms.

Kuzmanovic T, Patel BJ, Sanikommu SR, Nagata Y, Awada H, Kerr CM, Przychodzen BP, Jha BK, Hiwase D, Singhal D, Advani AS, Nazha A, Gerds AT, Carraway HE, Sekeres MA, Mukherjee S, Maciejewski JP, Radivoyevitch T.

Haematologica. 2019 Aug 14. pii: haematol.2019.219352. doi: 10.3324/haematol.2019.219352. [Epub ahead of print]

3.

Scaling Up Safer Birth Bundle Through Quality Improvement in Nepal (SUSTAIN)-a stepped wedge cluster randomized controlled trial in public hospitals.

Gurung R, Jha AK, Pyakurel S, Gurung A, Litorp H, Wrammert J, Jha BK, Paudel P, Rahman SM, Malla H, Sharma S, Gautam M, Linde JE, Moinuddin M, Ewald U, Målqvist M, Axelin A, Kc A.

Implement Sci. 2019 Jun 19;14(1):65. doi: 10.1186/s13012-019-0917-z.

4.

Development of a Cx46 Targeting Strategy for Cancer Stem Cells.

Mulkearns-Hubert EE, Torre-Healy LA, Silver DJ, Eurich JT, Bayik D, Serbinowski E, Hitomi M, Zhou J, Przychodzen B, Zhang R, Sprowls SA, Hale JS, Alban TJ, Berezovsky A, Bell BA, Lockman PR, Jha BK, Lathia JD.

Cell Rep. 2019 Apr 23;27(4):1062-1072.e5. doi: 10.1016/j.celrep.2019.03.079.

5.

TET2 mutations and clonal dynamics.

Kishtagari A, Jha BK, Maciejewski JP.

Oncotarget. 2019 Mar 12;10(21):2010-2011. doi: 10.18632/oncotarget.26779. eCollection 2019 Mar 12. No abstract available.

6.

Invariant phenotype and molecular association of biallelic TET2 mutant myeloid neoplasia.

Awada H, Nagata Y, Goyal A, Asad MF, Patel B, Hirsch CM, Kuzmanovic T, Guan Y, Przychodzen BP, Aly M, Adema V, Shen W, Williams L, Nazha A, Abazeed ME, Sekeres MA, Radivoyevitch T, Haferlach T, Jha BK, Visconte V, Maciejewski JP.

Blood Adv. 2019 Feb 12;3(3):339-349. doi: 10.1182/bloodadvances.2018024216.

7.

Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites.

Varikuti S, Jha BK, Volpedo G, Ryan NM, Halsey G, Hamza OM, McGwire BS, Satoskar AR.

Front Microbiol. 2018 Nov 30;9:2655. doi: 10.3389/fmicb.2018.02655. eCollection 2018. Review.

8.

Hepatic artery pseudoaneurysm, bronchobiliary fistula in a patient with liver trauma.

Jha P, Joshi BD, Jha BK.

BMC Surg. 2018 Nov 12;18(1):97. doi: 10.1186/s12893-018-0437-9.

9.

Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes.

Nagata Y, Narumi S, Guan Y, Przychodzen BP, Hirsch CM, Makishima H, Shima H, Aly M, Pastor V, Kuzmanovic T, Radivoyevitch T, Adema V, Awada H, Yoshida K, Li S, Sole F, Hanna R, Jha BK, LaFramboise T, Ogawa S, Sekeres MA, Wlodarski MW, Cammenga J, Maciejewski JP.

Blood. 2018 Nov 22;132(21):2309-2313. doi: 10.1182/blood-2017-05-787390. Epub 2018 Oct 15. No abstract available.

PMID:
30322869
10.

Case study: patient-derived clear cell adenocarcinoma xenograft model longitudinally predicts treatment response.

Vargas R, Gopal P, Kuzmishin GB, DeBernardo R, Koyfman SA, Jha BK, Mian OY, Scott J, Adams DJ, Peacock CD, Abazeed ME.

NPJ Precis Oncol. 2018 Jul 11;2:14. doi: 10.1038/s41698-018-0060-3. eCollection 2018.

11.

Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates.

Gu X, Ebrahem Q, Mahfouz RZ, Hasipek M, Enane F, Radivoyevitch T, Rapin N, Przychodzen B, Hu Z, Balusu R, Cotta CV, Wald D, Argueta C, Landesman Y, Martelli MP, Falini B, Carraway H, Porse BT, Maciejewski J, Jha BK, Saunthararajah Y.

J Clin Invest. 2018 Oct 1;128(10):4260-4279. doi: 10.1172/JCI97117. Epub 2018 Jul 17.

12.

Consequences of mutant TET2 on clonality and subclonal hierarchy.

Hirsch CM, Nazha A, Kneen K, Abazeed ME, Meggendorfer M, Przychodzen BP, Nadarajah N, Adema V, Nagata Y, Goyal A, Awada H, Asad MF, Visconte V, Guan Y, Sekeres MA, Olinski R, Jha BK, LaFramboise T, Radivoyevitch T, Haferlach T, Maciejewski JP.

Leukemia. 2018 Aug;32(8):1751-1761. doi: 10.1038/s41375-018-0150-9. Epub 2018 May 24.

PMID:
29795413
13.

A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.

Drappier M, Jha BK, Stone S, Elliott R, Zhang R, Vertommen D, Weiss SR, Silverman RH, Michiels T.

PLoS Pathog. 2018 Apr 13;14(4):e1006989. doi: 10.1371/journal.ppat.1006989. eCollection 2018 Apr.

14.

Genetic polymorphisms of N-acetyltransferase 2 & susceptibility to antituberculosis drug-induced hepatotoxicity.

Sharma SK, Jha BK, Sharma A, Sreenivas V, Upadhyay V, Jaisinghani C, Singla R, Mishra HK, Soneja M.

Indian J Med Res. 2016 Dec;144(6):924-928. doi: 10.4103/ijmr.IJMR_684_14.

15.

Visual outcome and early complications of sutureless and glueless scleral fixated intraocular lens.

Agarwal L, Agarwal N, Gurung RL, Chaubey R, Jha BK, Chaudhary BP.

Nepal J Ophthalmol. 2016 Jan;8(15):41-46. doi: 10.3126/nepjoph.v8i1.16155.

PMID:
28242884
16.

Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L.

Goldstein SA, Thornbrough JM, Zhang R, Jha BK, Li Y, Elliott R, Quiroz-Figueroa K, Chen AI, Silverman RH, Weiss SR.

J Virol. 2017 Feb 14;91(5). pii: e02201-16. doi: 10.1128/JVI.02201-16. Print 2017 Mar 1.

17.

Portraying the Effect of Calcium-Binding Proteins on Cytosolic Calcium Concentration Distribution Fractionally in Nerve Cells.

Jha BK, Joshi H, Dave DD.

Interdiscip Sci. 2018 Dec;10(4):674-685. doi: 10.1007/s12539-016-0202-7. Epub 2016 Nov 23.

PMID:
27882454
18.

Oral hygiene practices and their socio-demographic correlates among Nepalese adult: evidence from non communicable diseases risk factors STEPS survey Nepal 2013.

Thapa P, Aryal KK, Mehata S, Vaidya A, Jha BK, Dhimal M, Pradhan S, Dhakal P, Pandit A, Pandey AR, Bista B, Pokhrel AU, Karki KB.

BMC Oral Health. 2016 Sep 29;16(1):105.

19.

Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma.

Vatolin S, Phillips JG, Jha BK, Govindgari S, Hu J, Grabowski D, Parker Y, Lindner DJ, Zhong F, Distelhorst CW, Smith MR, Cotta C, Xu Y, Chilakala S, Kuang RR, Tall S, Reu FJ.

Cancer Res. 2016 Jun 1;76(11):3340-50. doi: 10.1158/0008-5472.CAN-15-3099. Epub 2016 Apr 6.

20.

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.

Thornbrough JM, Jha BK, Yount B, Goldstein SA, Li Y, Elliott R, Sims AC, Baric RS, Silverman RH, Weiss SR.

MBio. 2016 Mar 29;7(2):e00258. doi: 10.1128/mBio.00258-16.

21.

Menopausal Health Status of Women of Kapilvastu District of Nepal.

Ghimire N, Dhakal P, Norrish D, Dangal G, Sharma D, Dhimal M, Aryal KK, Jha BK, Karki KB.

J Nepal Health Res Counc. 2015 Sep-Dec;13(31):182-7.

PMID:
27005709
22.

Dengue virus infection in a French traveller to the hilly region of Nepal in 2015: a case report.

Gupta BP, Adhikari A, Rauniyar R, Kurmi R, Upadhya BP, Jha BK, Pandey B, Das Manandhar K.

J Med Case Rep. 2016 Mar 21;10:65. doi: 10.1186/s13256-016-0847-1.

23.

Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation.

Sui B, Huang J, Jha BK, Yin P, Zhou M, Fu ZF, Silverman RH, Weiss SR, Peng G, Zhao L.

J Gen Virol. 2016 Apr;97(4):880-6. doi: 10.1099/jgv.0.000395. Epub 2016 Jan 11.

24.
25.

Study of conformational properties of solid phase synthesized ovine kisspeptin-14 using Circular Dichroism spectroscopy.

Saxena VK, Kumar S, Jha BK, Kumar A, Kumar D, Naqvi SM.

Indian J Exp Biol. 2015 Oct;53(10):676-80.

PMID:
26665299
26.

Juglone induces cell death of Acanthamoeba through increased production of reactive oxygen species.

Jha BK, Jung HJ, Seo I, Suh SI, Suh MH, Baek WK.

Exp Parasitol. 2015 Dec;159:100-6. doi: 10.1016/j.exppara.2015.09.005. Epub 2015 Sep 7.

PMID:
26358271
27.

Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.

Ogden KM, Hu L, Jha BK, Sankaran B, Weiss SR, Silverman RH, Patton JT, Prasad BV.

J Virol. 2015 Jul;89(13):6633-45.

28.

Assessment of Genetic Variability in the Coding Sequence of Melatonin Receptor Gene (MTNR1A) in Tropical Arid Sheep Breeds of India.

Saxena VK, Jha BK, Meena AS, Narula HK, Kumar D, Naqvi SM.

Reprod Domest Anim. 2015 Jun;50(3):517-21. doi: 10.1111/rda.12503. Epub 2015 Feb 23.

PMID:
25708518
29.

Sequence analysis and identification of new variations in the coding sequence of melatonin receptor gene (MTNR1A) of Indian Chokla sheep breed.

Saxena VK, Jha BK, Meena AS, Naqvi SM.

Meta Gene. 2014 Jun 28;2:450-8. doi: 10.1016/j.mgene.2014.05.005. eCollection 2014 Dec.

30.

Tigecycline inhibits proliferation of Acanthamoeba castellanii.

Jha BK, Seo I, Kong HH, Suh SI, Suh MH, Baek WK.

Parasitol Res. 2015 Mar;114(3):1189-95. doi: 10.1007/s00436-014-4302-1. Epub 2015 Jan 7.

PMID:
25563616
31.

Pancytopenia in a surgical patient, a rare presentation of hyperthyroidism.

Jha P, Singh YP, Ghimire B, Jha BK.

BMC Surg. 2014 Dec 15;14:108. doi: 10.1186/1471-2482-14-108.

32.

Incidence of metallo-beta-lactamase producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in central Nepal.

Bora A, Sanjana R, Jha BK, Mahaseth SN, Pokharel K.

BMC Res Notes. 2014 Aug 21;7:557. doi: 10.1186/1756-0500-7-557.

33.

Chloroquine has a cytotoxic effect on Acanthamoeba encystation through modulation of autophagy.

Jha BK, Jung HJ, Seo I, Kim HA, Suh SI, Suh MH, Baek WK.

Antimicrob Agents Chemother. 2014 Oct;58(10):6235-41. doi: 10.1128/AAC.03164-14. Epub 2014 Aug 11.

34.

Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway.

Park JY, Jung HJ, Seo I, Jha BK, Suh SI, Suh MH, Baek WK.

Cell Oncol (Dordr). 2014 Aug;37(4):269-79. doi: 10.1007/s13402-014-0182-8. Epub 2014 Jul 29.

PMID:
25070654
35.

Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene.

Gusho E, Zhang R, Jha BK, Thornbrough JM, Dong B, Gaughan C, Elliott R, Weiss SR, Silverman RH.

MBio. 2014 Jul 1;5(4):e01312-14. doi: 10.1128/mBio.01312-14.

36.

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.

Agyeman A, Jha BK, Mazumdar T, Houghton JA.

Oncotarget. 2014 Jun 30;5(12):4492-503.

37.

Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity.

Sharma SK, Jha BK, Sharma A, Sreenivas V, Upadhyay V, Jaisinghani C, Singla R, Mishra HK, Soneja M.

Int J Tuberc Lung Dis. 2014 May;18(5):588-93. doi: 10.5588/ijtld.13.0344.

PMID:
24903797
38.

Identification of lysosomotropic compounds based on the distribution and size of lysosomes.

Seo I, Jha BK, Lim JG, Suh SI, Suh MH, Baek WK.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):189-94. doi: 10.1016/j.bbrc.2014.05.091. Epub 2014 May 27.

PMID:
24878535
39.

Cell-type-specific effects of RNase L on viral induction of beta interferon.

Banerjee S, Chakrabarti A, Jha BK, Weiss SR, Silverman RH.

MBio. 2014 Feb 25;5(2):e00856-14. doi: 10.1128/mBio.00856-14.

40.

Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs.

Cooper DA, Jha BK, Silverman RH, Hesselberth JR, Barton DJ.

Nucleic Acids Res. 2014 Apr;42(8):5202-16. doi: 10.1093/nar/gku118. Epub 2014 Feb 5.

41.

Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.

Huang H, Zeqiraj E, Dong B, Jha BK, Duffy NM, Orlicky S, Thevakumaran N, Talukdar M, Pillon MC, Ceccarelli DF, Wan LC, Juang YC, Mao DY, Gaughan C, Brinton MA, Perelygin AA, Kourinov I, Guarné A, Silverman RH, Sicheri F.

Mol Cell. 2014 Jan 23;53(2):221-34. doi: 10.1016/j.molcel.2013.12.025.

42.

Minocycline inhibits angiogenesis in vitro through the translational suppression of HIF-1α.

Jung HJ, Seo I, Jha BK, Suh SI, Suh MH, Baek WK.

Arch Biochem Biophys. 2014 Mar 1;545:74-82. doi: 10.1016/j.abb.2013.12.023. Epub 2014 Jan 8.

PMID:
24412777
43.

Assessment of district health system within inter-sectoral context in Nepal.

Bhusal CL, Singh SP, Aryal KK, Jha BK, Ghimire N, Shah N, Khatiwada D, Magar A.

J Nepal Health Res Counc. 2013 May;11(24):163-76.

PMID:
24362606
44.

Role of ribonuclease L in viral pathogen-associated molecular pattern/influenza virus and cigarette smoke-induced inflammation and remodeling.

Zhou Y, Kang MJ, Jha BK, Silverman RH, Lee CG, Elias JA.

J Immunol. 2013 Sep 1;191(5):2637-46. doi: 10.4049/jimmunol.1300082. Epub 2013 Aug 2.

45.

Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.

Zhang R, Jha BK, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH, Weiss SR.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13114-9. doi: 10.1073/pnas.1306917110. Epub 2013 Jul 22.

46.

Loop-mediated isothermal amplification targeting 18S ribosomal DNA for rapid detection of Acanthamoeba.

Yang HW, Lee YR, Inoue N, Jha BK, Danne DB, Kim HK, Lee J, Goo YK, Kong HH, Chung DI, Hong Y.

Korean J Parasitol. 2013 Jun;51(3):269-77. doi: 10.3347/kjp.2013.51.3.269. Epub 2013 Jun 30.

47.

Evaluation of the efficacy of chloroquine chemoprophylaxis for vivax malaria among Republic of Korea military personnel.

Jeong S, Yang HW, Yoon YR, Lee WK, Lee YR, Jha BK, Sylvatrie-Danne DB, Kim S, Jeong C, Kong HH, Goo YK, Hong Y, Chung DI.

Parasitol Int. 2013 Dec;62(6):494-6. doi: 10.1016/j.parint.2013.07.002. Epub 2013 Jul 12.

PMID:
23850837
48.

Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L.

Sorgeloos F, Jha BK, Silverman RH, Michiels T.

PLoS Pathog. 2013;9(6):e1003474. doi: 10.1371/journal.ppat.1003474. Epub 2013 Jun 27.

49.

Suppression of antiviral innate immunity by sunitinib enhances oncolytic virotherapy.

Jha BK, Dong B, Nguyen CT, Polyakova I, Silverman RH.

Mol Ther. 2013 Sep;21(9):1749-57. doi: 10.1038/mt.2013.112. Epub 2013 Jun 4.

50.

Cysteine protease inhibitor (AcStefin) is required for complete cyst formation of Acanthamoeba.

Lee JY, Song SM, Moon EK, Lee YR, Jha BK, Danne DB, Cha HJ, Yu HS, Kong HH, Chung DI, Hong Y.

Eukaryot Cell. 2013 Apr;12(4):567-74. doi: 10.1128/EC.00308-12. Epub 2013 Feb 8.

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