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Items: 25


RIP2 promotes FcγR-mediated reactive oxygen species production.

Shehat MG, Cardona OA, Aranjuez GF, Jewett MW, Tigno-Aranjuez JT.

J Biol Chem. 2019 Jun 28;294(26):10365-10378. doi: 10.1074/jbc.RA118.007218. Epub 2019 May 21.


Borrelia burgdorferi bbk13 Is Critical for Spirochete Population Expansion in the Skin during Early Infection.

Aranjuez GF, Kuhn HW, Adams PP, Jewett MW.

Infect Immun. 2019 Apr 23;87(5). pii: e00887-18. doi: 10.1128/IAI.00887-18. Print 2019 Mar.


Selection of Borrelia burgdorferi Promoter Sequences Active During Mammalian Infection Using In Vivo Expression Technology.

Adams PP, Jewett MW.

Methods Mol Biol. 2018;1690:137-154. doi: 10.1007/978-1-4939-7383-5_12.


Metabolic differentiation of early Lyme disease from southern tick-associated rash illness (STARI).

Molins CR, Ashton LV, Wormser GP, Andre BG, Hess AM, Delorey MJ, Pilgard MA, Johnson BJ, Webb K, Islam MN, Pegalajar-Jurado A, Molla I, Jewett MW, Belisle JT.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaal2717. doi: 10.1126/scitranslmed.aal2717.


A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions.

Adams PP, Flores Avile C, Jewett MW.

Front Cell Infect Microbiol. 2017 May 31;7:225. doi: 10.3389/fcimb.2017.00225. eCollection 2017.


In vivo expression technology and 5' end mapping of the Borrelia burgdorferi transcriptome identify novel RNAs expressed during mammalian infection.

Adams PP, Flores Avile C, Popitsch N, Bilusic I, Schroeder R, Lybecker M, Jewett MW.

Nucleic Acids Res. 2017 Jan 25;45(2):775-792. doi: 10.1093/nar/gkw1180. Epub 2016 Dec 1.


Gene bb0318 Is Critical for the Oxidative Stress Response and Infectivity of Borrelia burgdorferi.

Showman AC, Aranjuez G, Adams PP, Jewett MW.

Infect Immun. 2016 Oct 17;84(11):3141-3151. doi: 10.1128/IAI.00430-16. Print 2016 Nov.


Molecular dissection of a Borrelia burgdorferi in vivo essential purine transport system.

Jain S, Showman AC, Jewett MW.

Infect Immun. 2015 Jun;83(6):2224-33. doi: 10.1128/IAI.02859-14. Epub 2015 Mar 16.


Correction: In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in Mice.

Ellis TC, Jain S, Linowski AK, Rike K, Bestor A, Rosa PA, Halpern M, Kurhanewicz S, Jewett MW.

PLoS Pathog. 2014 Jun 20;10(6):e1004260. doi: 10.1371/journal.ppat.1004260. eCollection 2014 Jun.


Simple objective detection of human lyme disease infection using immuno-PCR and a single recombinant hybrid antigen.

Halpern MD, Molins CR, Schriefer M, Jewett MW.

Clin Vaccine Immunol. 2014 Aug;21(8):1094-105. doi: 10.1128/CVI.00245-14. Epub 2014 Jun 4.


In vivo expression technology identifies a novel virulence factor critical for Borrelia burgdorferi persistence in mice.

Ellis TC, Jain S, Linowski AK, Rike K, Bestor A, Rosa PA, Halpern M, Kurhanewicz S, Jewett MW.

PLoS Pathog. 2013;9(8):e1003567. doi: 10.1371/journal.ppat.1003567. Epub 2013 Aug 29. Erratum in: PLoS Pathog. 2014 Jun;10(6). doi:10.1371/journal.ppat.1004260. Corrected and republished in: PLoS Pathog. 2014 Jun;10(6):e1004260.


Enhanced detection of host response antibodies to Borrelia burgdorferi using immuno-PCR.

Halpern MD, Jain S, Jewett MW.

Clin Vaccine Immunol. 2013 Mar;20(3):350-7. doi: 10.1128/CVI.00630-12. Epub 2013 Jan 9.


An allele of an ancestral transcription factor dependent on a horizontally acquired gene product.

Chen HD, Jewett MW, Groisman EA.

PLoS Genet. 2012;8(12):e1003060. doi: 10.1371/journal.pgen.1003060. Epub 2012 Dec 27.


Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection.

Jain S, Sutchu S, Rosa PA, Byram R, Jewett MW.

Infect Immun. 2012 Sep;80(9):3086-93. doi: 10.1128/IAI.00514-12. Epub 2012 Jun 18.


Ancestral genes can control the ability of horizontally acquired loci to confer new traits.

Chen HD, Jewett MW, Groisman EA.

PLoS Genet. 2011 Jul;7(7):e1002184. doi: 10.1371/journal.pgen.1002184. Epub 2011 Jul 21.


Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA.

Jewett MW, Jain S, Linowski AK, Sarkar A, Rosa PA.

Microbiology. 2011 Oct;157(Pt 10):2831-2840. doi: 10.1099/mic.0.051706-0. Epub 2011 Jul 21.


lacZ reporter system for use in Borrelia burgdorferi.

Hayes BM, Jewett MW, Rosa PA.

Appl Environ Microbiol. 2010 Nov;76(22):7407-12. doi: 10.1128/AEM.01389-10. Epub 2010 Sep 17.


Use of the Cre-lox recombination system to investigate the lp54 gene requirement in the infectious cycle of Borrelia burgdorferi.

Bestor A, Stewart PE, Jewett MW, Sarkar A, Tilly K, Rosa PA.

Infect Immun. 2010 Jun;78(6):2397-407. doi: 10.1128/IAI.01059-09. Epub 2010 Mar 15.


GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle.

Jewett MW, Lawrence KA, Bestor A, Byram R, Gherardini F, Rosa PA.

J Bacteriol. 2009 Oct;191(20):6231-41. doi: 10.1128/JB.00450-09. Epub 2009 Aug 7.


Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage.

Lawrence KA, Jewett MW, Rosa PA, Gherardini FC.

Mol Microbiol. 2009 Jun;72(6):1517-29. doi: 10.1111/j.1365-2958.2009.06740.x. Epub 2009 May 15.


Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria.

Mitrophanov AY, Jewett MW, Hadley TJ, Groisman EA.

PLoS Genet. 2008 Oct;4(10):e1000233. doi: 10.1371/journal.pgen.1000233. Epub 2008 Oct 24.


Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi.

Jewett MW, Byram R, Bestor A, Tilly K, Lawrence K, Burtnick MN, Gherardini F, Rosa PA.

Mol Microbiol. 2007 Nov;66(4):975-90. Epub 2007 Oct 4.


The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi.

Jewett MW, Lawrence K, Bestor AC, Tilly K, Grimm D, Shaw P, VanRaden M, Gherardini F, Rosa PA.

Mol Microbiol. 2007 Jun;64(5):1358-74.


Rapid clearance of Lyme disease spirochetes lacking OspC from skin.

Tilly K, Bestor A, Jewett MW, Rosa P.

Infect Immun. 2007 Mar;75(3):1517-9. Epub 2006 Dec 11.


Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection.

Tilly K, Krum JG, Bestor A, Jewett MW, Grimm D, Bueschel D, Byram R, Dorward D, Vanraden MJ, Stewart P, Rosa P.

Infect Immun. 2006 Jun;74(6):3554-64.

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