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Items: 1 to 50 of 84

1.

INTESTINAL TOXICITY IN RATS FOLLOWING ADMINISTRATION OF CDK4/6 INHIBITORS IS INDEPENDENT OF PRIMARY PHARMACOLOGY.

Thibault S, Hu W, Hirakawa B, Kalabat D, Franks T, Sung T, Khoh-Reiter S, Lu S, Finkelstein M, Jessen B, Sacaan AI.

Mol Cancer Ther. 2018 Nov 6. pii: molcanther.0734.2018. doi: 10.1158/1535-7163.MCT-18-0734. [Epub ahead of print]

PMID:
30401694
2.

Quantitative optical mapping of two-dimensional materials.

Jessen BS, Whelan PR, Mackenzie DMA, Luo B, Thomsen JD, Gammelgaard L, Booth TJ, Bøggild P.

Sci Rep. 2018 Apr 23;8(1):6381. doi: 10.1038/s41598-018-23922-1.

3.

Lysosomal adaptation: How cells respond to lysosomotropic compounds.

Lu S, Sung T, Lin N, Abraham RT, Jessen BA.

PLoS One. 2017 Mar 16;12(3):e0173771. doi: 10.1371/journal.pone.0173771. eCollection 2017.

4.

Catalyst Interface Engineering for Improved 2D Film Lift-Off and Transfer.

Wang R, Whelan PR, Braeuninger-Weimer P, Tappertzhofen S, Alexander-Webber JA, Van Veldhoven ZA, Kidambi PR, Jessen BS, Booth T, Bøggild P, Hofmann S.

ACS Appl Mater Interfaces. 2016 Dec 7;8(48):33072-33082. Epub 2016 Nov 22.

5.

Validation of Cross-Species Reactivity of the VEGF-A/PDGFRβ Bifunctional Antibody PF-06653157.

Ashoor R, Lee D, Cheng A, Jessen B, Huang W.

J Ocul Pharmacol Ther. 2016 Dec;32(10):650-658. Epub 2016 Oct 13.

PMID:
27736501
6.

The hot pick-up technique for batch assembly of van der Waals heterostructures.

Pizzocchero F, Gammelgaard L, Jessen BS, Caridad JM, Wang L, Hone J, Bøggild P, Booth TJ.

Nat Commun. 2016 Jun 16;7:11894. doi: 10.1038/ncomms11894.

7.

Mechanistic Investigation of Bone Marrow Suppression Associated with Palbociclib and its Differentiation from Cytotoxic Chemotherapies.

Hu W, Sung T, Jessen BA, Thibault S, Finkelstein MB, Khan NK, Sacaan AI.

Clin Cancer Res. 2016 Apr 15;22(8):2000-8. doi: 10.1158/1078-0432.CCR-15-1421. Epub 2015 Dec 2.

8.

Graphene mobility mapping.

Buron JD, Pizzocchero F, Jepsen PU, Petersen DH, Caridad JM, Jessen BS, Booth TJ, Bøggild P.

Sci Rep. 2015 Jul 24;5:12305. doi: 10.1038/srep12305.

9.

Multi-terminal transport measurements of MoS2 using a van der Waals heterostructure device platform.

Cui X, Lee GH, Kim YD, Arefe G, Huang PY, Lee CH, Chenet DA, Zhang X, Wang L, Ye F, Pizzocchero F, Jessen BS, Watanabe K, Taniguchi T, Muller DA, Low T, Kim P, Hone J.

Nat Nanotechnol. 2015 Jun;10(6):534-40. doi: 10.1038/nnano.2015.70. Epub 2015 Apr 27.

PMID:
25915194
10.

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.

Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C; Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK.

Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20.

11.

Perioperative myocardial infarction in patients undergoing myocardial revascularization surgery.

Pretto P, Martins GF, Biscaro A, Kruczan DD, Jessen B.

Rev Bras Cir Cardiovasc. 2015 Jan-Mar;30(1):49-54. doi: 10.5935/1678-9741.20140059.

12.

Biotin[6]uril Esters: Chloride-Selective Transmembrane Anion Carriers Employing C-H···Anion Interactions.

Lisbjerg M, Valkenier H, Jessen BM, Al-Kerdi H, Davis AP, Pittelkow M.

J Am Chem Soc. 2015 Apr 22;137(15):4948-51. doi: 10.1021/jacs.5b02306. Epub 2015 Apr 8.

PMID:
25851041
13.

Defect/oxygen assisted direct write technique for nanopatterning graphene.

Cagliani A, Lindvall N, Larsen MB, Mackenzie DM, Jessen BS, Booth TJ, Bøggild P.

Nanoscale. 2015 Apr 14;7(14):6271-7. doi: 10.1039/c4nr07585d.

PMID:
25779889
14.

Contribution of membrane trafficking perturbation to retinal toxicity.

Khoh-Reiter S, Sokolowski SA, Jessen B, Evans M, Dalvie D, Lu S.

Toxicol Sci. 2015 Jun;145(2):383-95. doi: 10.1093/toxsci/kfv059. Epub 2015 Mar 13.

PMID:
25771199
15.

Correction to graphene uniformity conductance mapping.

Buron JD, Petersen DH, Bøggild P, Cooke DG, Hilke M, Sun J, Whiteway E, Jessen BS, Nielsen PF, Hansen O, Yurgens A, Jepsen PU.

Nano Lett. 2015 Jan 14;15(1):803. doi: 10.1021/nl504550p. Epub 2014 Dec 3. No abstract available.

PMID:
25470179
16.

Combination of 4-1BB agonist and PD-1 antagonist promotes antitumor effector/memory CD8 T cells in a poorly immunogenic tumor model.

Chen S, Lee LF, Fisher TS, Jessen B, Elliott M, Evering W, Logronio K, Tu GH, Tsaparikos K, Li X, Wang H, Ying C, Xiong M, VanArsdale T, Lin JC.

Cancer Immunol Res. 2015 Feb;3(2):149-60. doi: 10.1158/2326-6066.CIR-14-0118. Epub 2014 Nov 11.

17.

Electrically continuous graphene from single crystal copper verified by terahertz conductance spectroscopy and micro four-point probe.

Buron JD, Pizzocchero F, Jessen BS, Booth TJ, Nielsen PF, Hansen O, Hilke M, Whiteway E, Jepsen PU, Bøggild P, Petersen DH.

Nano Lett. 2014 Nov 12;14(11):6348-55. doi: 10.1021/nl5028167. Epub 2014 Oct 21.

PMID:
25317778
18.

Investigation of ocular events associated with taprenepag isopropyl, a topical EP2 agonist in development for treatment of glaucoma.

Yanochko GM, Affolter T, Eighmy JJ, Evans MG, Khoh-Reiter S, Lee D, Miller PE, Shiue MH, Trajkovic D, Jessen BA.

J Ocul Pharmacol Ther. 2014 Jun;30(5):429-39. doi: 10.1089/jop.2013.0222. Epub 2014 Apr 10.

PMID:
24720348
19.

Graded defects in cytotoxicity determine severity of hemophagocytic lymphohistiocytosis in humans and mice.

Jessen B, Kögl T, Sepulveda FE, de Saint Basile G, Aichele P, Ehl S.

Front Immunol. 2013 Dec 16;4:448. doi: 10.3389/fimmu.2013.00448. eCollection 2013.

20.

The contribution of lysosomotropism to autophagy perturbation.

Ashoor R, Yafawi R, Jessen B, Lu S.

PLoS One. 2013 Nov 22;8(11):e82481. doi: 10.1371/journal.pone.0082481. eCollection 2013.

21.

Cardiovascular differentiation of imatinib and bosutinib in the rat.

Heyen JR, Hu W, Jamieson J, Thibault S, Batugo M, Loi CM, Burns-Naas LA, McHarg AD, Jessen B.

Int J Hematol. 2013 Nov;98(5):597-607. doi: 10.1007/s12185-013-1453-2. Epub 2013 Oct 19.

PMID:
24142766
22.

Safety assessment of subconjunctivally implanted devices containing latanoprost in Dutch-belted rabbits.

Jessen BA, Shiue MH, Kaur H, Miller P, Leedle R, Guo H, Evans M.

J Ocul Pharmacol Ther. 2013 Jul-Aug;29(6):574-85. doi: 10.1089/jop.2012.0190. Epub 2013 Mar 14.

PMID:
23489175
23.

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2.

Jessen B, Bode SF, Ammann S, Chakravorty S, Davies G, Diestelhorst J, Frei-Jones M, Gahl WA, Gochuico BR, Griese M, Griffiths G, Janka G, Klein C, Kögl T, Kurnik K, Lehmberg K, Maul-Pavicic A, Mumford AD, Pace D, Parvaneh N, Rezaei N, de Saint Basile G, Schmitt-Graeff A, Schwarz K, Karasu GT, Zieger B, Zur Stadt U, Aichele P, Ehl S.

Blood. 2013 Apr 11;121(15):2943-51. doi: 10.1182/blood-2012-10-463166. Epub 2013 Feb 12.

24.

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease.

Kögl T, Müller J, Jessen B, Schmitt-Graeff A, Janka G, Ehl S, zur Stadt U, Aichele P.

Blood. 2013 Jan 24;121(4):604-13. doi: 10.1182/blood-2012-07-441139. Epub 2012 Nov 27.

25.

A tyrosine kinase inhibitor-induced myocardial degeneration in rats through off-target phosphodiesterase inhibition.

Hu W, Hirakawa B, Jessen B, Lee M, Aguirre S.

J Appl Toxicol. 2012 Dec;32(12):1008-20. doi: 10.1002/jat.2801. Epub 2012 Aug 31.

PMID:
22936366
26.

Trimetazidine and inflammatory response in coronary artery bypass grafting.

Martins GF, Siqueira Filho AG, Santos JB, Assunção CR, Vieira FB, Valência A, Carvalho KG, Jessen B.

Arq Bras Cardiol. 2012 Aug;99(2):688-96. Epub 2012 Jul 13. English, Portuguese.

27.

Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.

Hu W, Lu S, McAlpine I, Jamieson JD, Lee DU, Marroquin LD, Heyen JR, Jessen BA.

Toxicol Sci. 2012 Sep;129(1):188-99. doi: 10.1093/toxsci/kfs192. Epub 2012 May 28.

PMID:
22641616
28.

The contribution of physicochemical properties to multiple in vitro cytotoxicity endpoints.

Lu S, Jessen B, Strock C, Will Y.

Toxicol In Vitro. 2012 Jun;26(4):613-20. doi: 10.1016/j.tiv.2012.01.025. Epub 2012 Feb 8.

PMID:
22342439
29.

Retina expression and cross-species validation of gene silencing by PF-655, a small interfering RNA against RTP801 for the treatment of ocular disease.

Lee DU, Huang W, Rittenhouse KD, Jessen B.

J Ocul Pharmacol Ther. 2012 Jun;28(3):222-30. doi: 10.1089/jop.2011.0116. Epub 2012 Feb 3.

PMID:
22304497
30.

Off-target immune cell toxicity caused by AG-012986, a pan-CDK inhibitor, is associated with inhibition of p38 MAPK phosphorylation.

Lee DU, Jessen B.

J Biochem Mol Toxicol. 2012 Mar;26(3):101-8. doi: 10.1002/jbt.20415. Epub 2011 Nov 16.

PMID:
22095879
31.

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.

Jessen B, Maul-Pavicic A, Ufheil H, Vraetz T, Enders A, Lehmberg K, Längler A, Gross-Wieltsch U, Bay A, Kaya Z, Bryceson YT, Koscielniak E, Badawy S, Davies G, Hufnagel M, Schmitt-Graeff A, Aichele P, Zur Stadt U, Schwarz K, Ehl S.

Blood. 2011 Oct 27;118(17):4620-9. doi: 10.1182/blood-2011-05-356113. Epub 2011 Aug 30.

32.

Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine aminotransferase gene expression and enzymatic activity in the rat liver.

Fuentealba C, Bera M, Jessen B, Sace F, Stevens GJ, Trajkovic D, Yang AH, Evering W.

Comp Hepatol. 2011 Aug 17;10:8. doi: 10.1186/1476-5926-10-8.

34.

Case reports: hyperbaric oxygen therapy for the treatment of cerebral air embolism.

Brito T, Pithan N, Martins G, Jessen B, Assumpção C, Porto T, Filho O, Siqueira-Filho A.

Undersea Hyperb Med. 2011 May-Jun;38(3):207-12.

PMID:
21721354
35.

Transient knock down of checkpoint kinase 1 in hematopoietic progenitors is linked to bone marrow toxicity.

Hu W, Zong Q, John-Baptiste A, Jessen B.

Toxicol Lett. 2011 Jul 28;204(2-3):141-7. doi: 10.1016/j.toxlet.2011.04.025. Epub 2011 Apr 30.

PMID:
21557990
36.

Lack of evidence for a link between latanoprost use and malignant melanoma: an analysis of safety databases and a review of the literature.

Tressler CS, Wiseman RL, Dombi TM, Jessen B, Huang K, Kwok KK, Wirostko BM.

Br J Ophthalmol. 2011 Nov;95(11):1490-5. doi: 10.1136/bjo.2010.193987. Epub 2011 Apr 21. Review.

PMID:
21515566
37.

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis.

Maul-Pavicic A, Chiang SC, Rensing-Ehl A, Jessen B, Fauriat C, Wood SM, Sjöqvist S, Hufnagel M, Schulze I, Bass T, Schamel WW, Fuchs S, Pircher H, McCarl CA, Mikoshiba K, Schwarz K, Feske S, Bryceson YT, Ehl S.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3324-9. doi: 10.1073/pnas.1013285108. Epub 2011 Feb 7.

38.

A high content screening assay for identifying lysosomotropic compounds.

Nadanaciva S, Lu S, Gebhard DF, Jessen BA, Pennie WD, Will Y.

Toxicol In Vitro. 2011 Apr;25(3):715-23. doi: 10.1016/j.tiv.2010.12.010. Epub 2010 Dec 22.

PMID:
21184822
39.

Light, genotype, and abscisic acid affect chloroplast positioning in guard cells of Arabidopsis thaliana leaves in distinct ways.

Königer M, Jessen B, Yang R, Sittler D, Harris GC.

Photosynth Res. 2010 Sep;105(3):213-27. doi: 10.1007/s11120-010-9580-6. Epub 2010 Jul 8.

PMID:
20614182
40.

Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections.

Mordstein M, Neugebauer E, Ditt V, Jessen B, Rieger T, Falcone V, Sorgeloos F, Ehl S, Mayer D, Kochs G, Schwemmle M, Günther S, Drosten C, Michiels T, Staeheli P.

J Virol. 2010 Jun;84(11):5670-7. doi: 10.1128/JVI.00272-10. Epub 2010 Mar 24.

41.

Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer.

Minner S, Jessen B, Stiedenroth L, Burandt E, Köllermann J, Mirlacher M, Erbersdobler A, Eichelberg C, Fisch M, Brümmendorf TH, Bokemeyer C, Simon R, Steuber T, Graefen M, Huland H, Sauter G, Schlomm T.

Clin Cancer Res. 2010 Mar 1;16(5):1553-60. doi: 10.1158/1078-0432.CCR-09-2546. Epub 2010 Feb 23.

42.

Comparison of preservative-induced toxicity on monolayer and stratified Chang conjunctival cells.

Yanochko GM, Khoh-Reiter S, Evans MG, Jessen BA.

Toxicol In Vitro. 2010 Jun;24(4):1324-31. doi: 10.1016/j.tiv.2010.02.001. Epub 2010 Feb 7.

PMID:
20144907
43.

Corneal neovascularization and ocular irritancy responses in dogs following topical ocular administration of an EP4-prostaglandin E2 agonist.

Aguirre SA, Huang W, Prasanna G, Jessen B.

Toxicol Pathol. 2009 Dec;37(7):911-20. doi: 10.1177/0192623309351724.

PMID:
20008547
44.
45.

Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells.

Will Y, Dykens JA, Nadanaciva S, Hirakawa B, Jamieson J, Marroquin LD, Hynes J, Patyna S, Jessen BA.

Toxicol Sci. 2008 Nov;106(1):153-61. doi: 10.1093/toxsci/kfn157. Epub 2008 Jul 29.

PMID:
18664550
46.

Clinical significance of p53 alterations in surgically treated prostate cancers.

Schlomm T, Iwers L, Kirstein P, Jessen B, Köllermann J, Minner S, Passow-Drolet A, Mirlacher M, Milde-Langosch K, Graefen M, Haese A, Steuber T, Simon R, Huland H, Sauter G, Erbersdobler A.

Mod Pathol. 2008 Nov;21(11):1371-8. doi: 10.1038/modpathol.2008.104. Epub 2008 Jun 13.

47.

Toxicity and toxicokinetics of the cyclin-dependent kinase inhibitor AG-024322 in cynomolgus monkeys following intravenous infusion.

Brown AP, Courtney CL, Criswell KA, Holliman CL, Evering W, Jessen BA.

Cancer Chemother Pharmacol. 2008 Nov;62(6):1091-101. doi: 10.1007/s00280-008-0771-1. Epub 2008 May 29.

PMID:
18509643
48.

Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.

Zhang C, Lundgren K, Yan Z, Arango ME, Price S, Huber A, Higgins J, Troche G, Skaptason J, Koudriakova T, Nonomiya J, Yang M, O'Connor P, Bender S, Los G, Lewis C, Jessen B.

Mol Cancer Ther. 2008 Apr;7(4):818-28. doi: 10.1158/1535-7163.MCT-07-0440.

49.

Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus.

Vallbracht S, Jessen B, Mrusek S, Enders A, Collins PL, Ehl S, Krempl CD.

J Immunol. 2007 Dec 15;179(12):8264-73.

50.

Antisense inhibition of 11betahydroxysteroid dehydrogenase type 1 improves diabetes in a novel cortisone-induced diabetic KK mouse model.

Bhat BG, Younis H, Herrera J, Palacio K, Pascual B, Hur G, Jessen B, Ogilvie KM, Rejto PA.

Biochem Biophys Res Commun. 2008 Jan 25;365(4):740-5. Epub 2007 Nov 20.

PMID:
18029262

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