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Items: 1 to 50 of 261


Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity.

Baek M, Menon V, Jessell TM, Hantman AW, Dasen JS.

Cell Rep. 2019 May 28;27(9):2620-2635.e4. doi: 10.1016/j.celrep.2019.04.113.


Positional Strategies for Connection Specificity and Synaptic Organization in Spinal Sensory-Motor Circuits.

Balaskas N, Abbott LF, Jessell TM, Ng D.

Neuron. 2019 Jun 19;102(6):1143-1156.e4. doi: 10.1016/j.neuron.2019.04.008. Epub 2019 May 7.


A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.

Wu D, Schieren I, Qian Y, Zhang C, Jessell TM, de Nooij JC.

J Neurosci. 2019 May 29;39(22):4252-4267. doi: 10.1523/JNEUROSCI.2671-18.2019. Epub 2019 Mar 29.


Subtype Diversification and Synaptic Specificity of Stem Cell-Derived Spinal Interneurons.

Hoang PT, Chalif JI, Bikoff JB, Jessell TM, Mentis GZ, Wichterle H.

Neuron. 2018 Oct 10;100(1):135-149.e7. doi: 10.1016/j.neuron.2018.09.016.


Sox14 Is Required for a Specific Subset of Cerebello-Olivary Projections.

Prekop HT, Kroiss A, Rook V, Zagoraiou L, Jessell TM, Fernandes C, Delogu A, Wingate RJT.

J Neurosci. 2018 Oct 31;38(44):9539-9550. doi: 10.1523/JNEUROSCI.1456-18.2018. Epub 2018 Sep 21.


Role of muscle spindle feedback in regulating muscle activity strength during walking at different speed in mice.

Mayer WP, Murray AJ, Brenner-Morton S, Jessell TM, Tourtellotte WG, Akay T.

J Neurophysiol. 2018 Nov 1;120(5):2484-2497. doi: 10.1152/jn.00250.2018. Epub 2018 Aug 22.


Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function.

Dewitz C, Pimpinella S, Hackel P, Akalin A, Jessell TM, Zampieri N.

Cell Rep. 2018 Feb 13;22(7):1681-1694. doi: 10.1016/j.celrep.2018.01.059.


Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response.

Russo AA, Bittner SR, Perkins SM, Seely JS, London BM, Lara AH, Miri A, Marshall NJ, Kohn A, Jessell TM, Abbott LF, Cunningham JP, Churchland MM.

Neuron. 2018 Feb 21;97(4):953-966.e8. doi: 10.1016/j.neuron.2018.01.004. Epub 2018 Feb 1.


Balance Control Mediated by Vestibular Circuits Directing Limb Extension or Antagonist Muscle Co-activation.

Murray AJ, Croce K, Belton T, Akay T, Jessell TM.

Cell Rep. 2018 Jan 30;22(5):1325-1338. doi: 10.1016/j.celrep.2018.01.009.


Origin and Segmental Diversity of Spinal Inhibitory Interneurons.

Sweeney LB, Bikoff JB, Gabitto MI, Brenner-Morton S, Baek M, Yang JH, Tabak EG, Dasen JS, Kintner CR, Jessell TM.

Neuron. 2018 Jan 17;97(2):341-355.e3. doi: 10.1016/j.neuron.2017.12.029. Epub 2018 Jan 4.


Behaviorally Selective Engagement of Short-Latency Effector Pathways by Motor Cortex.

Miri A, Warriner CL, Seely JS, Elsayed GF, Cunningham JP, Churchland MM, Jessell TM.

Neuron. 2017 Aug 2;95(3):683-696.e11. doi: 10.1016/j.neuron.2017.06.042. Epub 2017 Jul 20.


Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles.

Mendelsohn AI, Dasen JS, Jessell TM.

Neuron. 2017 Feb 22;93(4):792-805.e4. doi: 10.1016/j.neuron.2017.01.017. Epub 2017 Feb 9.


Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus.

Jager P, Ye Z, Yu X, Zagoraiou L, Prekop HT, Partanen J, Jessell TM, Wisden W, Brickley SG, Delogu A.

Nat Commun. 2016 Dec 8;7:13579. doi: 10.1038/ncomms13579.


Bayesian Sparse Regression Analysis Documents the Diversity of Spinal Inhibitory Interneurons.

Gabitto MI, Pakman A, Bikoff JB, Abbott LF, Jessell TM, Paninski L.

Cell. 2016 Mar 24;165(1):220-233. doi: 10.1016/j.cell.2016.01.026. Epub 2016 Mar 3.


Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits.

Bikoff JB, Gabitto MI, Rivard AF, Drobac E, Machado TA, Miri A, Brenner-Morton S, Famojure E, Diaz C, Alvarez FJ, Mentis GZ, Jessell TM.

Cell. 2016 Mar 24;165(1):207-219. doi: 10.1016/j.cell.2016.01.027. Epub 2016 Mar 3.


Muscle-type Identity of Proprioceptors Specified by Spatially Restricted Signals from Limb Mesenchyme.

Poliak S, Norovich AL, Yamagata M, Sanes JR, Jessell TM.

Cell. 2016 Jan 28;164(3):512-25. doi: 10.1016/j.cell.2015.12.049.


Rabies Virus CVS-N2c(ΔG) Strain Enhances Retrograde Synaptic Transfer and Neuronal Viability.

Reardon TR, Murray AJ, Turi GF, Wirblich C, Croce KR, Schnell MJ, Jessell TM, Losonczy A.

Neuron. 2016 Feb 17;89(4):711-24. doi: 10.1016/j.neuron.2016.01.004. Epub 2016 Jan 21.


Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data.

Pnevmatikakis EA, Soudry D, Gao Y, Machado TA, Merel J, Pfau D, Reardon T, Mu Y, Lacefield C, Yang W, Ahrens M, Bruno R, Jessell TM, Peterka DS, Yuste R, Paninski L.

Neuron. 2016 Jan 20;89(2):285-99. doi: 10.1016/j.neuron.2015.11.037. Epub 2016 Jan 7.


Piezo2 is the principal mechanotransduction channel for proprioception.

Woo SH, Lukacs V, de Nooij JC, Zaytseva D, Criddle CR, Francisco A, Jessell TM, Wilkinson KA, Patapoutian A.

Nat Neurosci. 2015 Dec;18(12):1756-62. doi: 10.1038/nn.4162. Epub 2015 Nov 9.


Primacy of Flexor Locomotor Pattern Revealed by Ancestral Reversion of Motor Neuron Identity.

Machado TA, Pnevmatikakis E, Paninski L, Jessell TM, Miri A.

Cell. 2015 Jul 16;162(2):338-350. doi: 10.1016/j.cell.2015.06.036.


Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections.

Mendelsohn AI, Simon CM, Abbott LF, Mentis GZ, Jessell TM.

Neuron. 2015 Jul 1;87(1):111-23. doi: 10.1016/j.neuron.2015.05.045. Epub 2015 Jun 18.


Internal and External Feedback Circuits for Skilled Forelimb Movement.

Azim E, Fink AJ, Jessell TM.

Cold Spring Harb Symp Quant Biol. 2014;79:81-92. doi: 10.1101/sqb.2014.79.024786. Epub 2015 Feb 19. Review.


The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors.

de Nooij JC, Simon CM, Simon A, Doobar S, Steel KP, Banks RW, Mentis GZ, Bewick GS, Jessell TM.

J Neurosci. 2015 Feb 18;35(7):3073-84. doi: 10.1523/JNEUROSCI.3699-14.2015.


Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback.

Akay T, Tourtellotte WG, Arber S, Jessell TM.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16877-82. doi: 10.1073/pnas.1419045111. Epub 2014 Nov 11.


QnAs with Thomas Jessell.

Jessell T, Nair P.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10394-5. doi: 10.1073/pnas.1409335111. Epub 2014 Jun 9. No abstract available.


Presynaptic inhibition of spinal sensory feedback ensures smooth movement.

Fink AJ, Croce KR, Huang ZJ, Abbott LF, Jessell TM, Azim E.

Nature. 2014 May 1;509(7498):43-8. doi: 10.1038/nature13276.


Skilled reaching relies on a V2a propriospinal internal copy circuit.

Azim E, Jiang J, Alstermark B, Jessell TM.

Nature. 2014 Apr 17;508(7496):357-63. doi: 10.1038/nature13021. Epub 2014 Feb 2.


Mapping sensory circuits by anterograde transsynaptic transfer of recombinant rabies virus.

Zampieri N, Jessell TM, Murray AJ.

Neuron. 2014 Feb 19;81(4):766-78. doi: 10.1016/j.neuron.2013.12.033. Epub 2014 Jan 30.


Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

Ashrafi S, Betley JN, Comer JD, Brenner-Morton S, Bar V, Shimoda Y, Watanabe K, Peles E, Jessell TM, Kaltschmidt JA.

Neuron. 2014 Jan 8;81(1):120-9. doi: 10.1016/j.neuron.2013.10.060.


Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons.

Dougherty KJ, Zagoraiou L, Satoh D, Rozani I, Doobar S, Arber S, Jessell TM, Kiehn O.

Neuron. 2013 Nov 20;80(4):920-33. doi: 10.1016/j.neuron.2013.08.015.


Specificity of monosynaptic sensory-motor connections imposed by repellent Sema3E-PlexinD1 signaling.

Fukuhara K, Imai F, Ladle DR, Katayama K, Leslie JR, Arber S, Jessell TM, Yoshida Y.

Cell Rep. 2013 Nov 14;5(3):748-58. doi: 10.1016/j.celrep.2013.10.005. Epub 2013 Nov 7.


Edging toward entelechy in motor control.

Miri A, Azim E, Jessell TM.

Neuron. 2013 Oct 30;80(3):827-34. doi: 10.1016/j.neuron.2013.10.049. Review.


Circuits for grasping: spinal dI3 interneurons mediate cutaneous control of motor behavior.

Bui TV, Akay T, Loubani O, Hnasko TS, Jessell TM, Brownstone RM.

Neuron. 2013 Apr 10;78(1):191-204. doi: 10.1016/j.neuron.2013.02.007.


Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets.

de Nooij JC, Doobar S, Jessell TM.

Neuron. 2013 Mar 20;77(6):1055-68. doi: 10.1016/j.neuron.2013.01.015.


Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms.

Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A.

Neuron. 2012 Aug 23;75(4):648-62. doi: 10.1016/j.neuron.2012.06.013.


Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai T, Mason C.

Neuron. 2012 May 24;74(4):676-90. doi: 10.1016/j.neuron.2012.03.025.


Motor neurons and the sense of place.

Jessell TM, Sürmeli G, Kelly JS.

Neuron. 2011 Nov 3;72(3):419-24. doi: 10.1016/j.neuron.2011.10.021. Review.


Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template.

Sürmeli G, Akay T, Ippolito GC, Tucker PW, Jessell TM.

Cell. 2011 Oct 28;147(3):653-65. doi: 10.1016/j.cell.2011.10.012.


Motor neuron position and topographic order imposed by β- and γ-catenin activities.

Demireva EY, Shapiro LS, Jessell TM, Zampieri N.

Cell. 2011 Oct 28;147(3):641-52. doi: 10.1016/j.cell.2011.09.037.


SnapShot: spinal cord development.

Alaynick WA, Jessell TM, Pfaff SL.

Cell. 2011 Jul 8;146(1):178-178.e1. doi: 10.1016/j.cell.2011.06.038. No abstract available.


A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning.

Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J.

Development. 2010 Dec;137(23):4051-60. doi: 10.1242/dev.054288.


Clarke's column neurons as the focus of a corticospinal corollary circuit.

Hantman AW, Jessell TM.

Nat Neurosci. 2010 Oct;13(10):1233-9. doi: 10.1038/nn.2637. Epub 2010 Sep 12.


Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation.

Peljto M, Dasen JS, Mazzoni EO, Jessell TM, Wichterle H.

Cell Stem Cell. 2010 Sep 3;7(3):355-66. doi: 10.1016/j.stem.2010.07.013.


T-cadherin structures reveal a novel adhesive binding mechanism.

Ciatto C, Bahna F, Zampieri N, VanSteenhouse HC, Katsamba PS, Ahlsen G, Harrison OJ, Brasch J, Jin X, Posy S, Vendome J, Ranscht B, Jessell TM, Honig B, Shapiro L.

Nat Struct Mol Biol. 2010 Mar;17(3):339-47. doi: 10.1038/nsmb.1781. Epub 2010 Feb 28.


A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.

Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB.

Neuron. 2009 Dec 10;64(5):645-62. doi: 10.1016/j.neuron.2009.10.017.


Measured motion: searching for simplicity in spinal locomotor networks.

Grillner S, Jessell TM.

Curr Opin Neurobiol. 2009 Dec;19(6):572-86. doi: 10.1016/j.conb.2009.10.011. Epub 2009 Nov 10. Review.


Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit.

Betley JN, Wright CV, Kawaguchi Y, Erdélyi F, Szabó G, Jessell TM, Kaltschmidt JA.

Cell. 2009 Oct 2;139(1):161-74. doi: 10.1016/j.cell.2009.08.027.


Gamma and alpha motor neurons distinguished by expression of transcription factor Err3.

Friese A, Kaltschmidt JA, Ladle DR, Sigrist M, Jessell TM, Arber S.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13588-93. doi: 10.1073/pnas.0906809106. Epub 2009 Jul 27.


Hox networks and the origins of motor neuron diversity.

Dasen JS, Jessell TM.

Curr Top Dev Biol. 2009;88:169-200. doi: 10.1016/S0070-2153(09)88006-X. Review.


Linking molecular affinity and cellular specificity in cadherin-mediated adhesion.

Katsamba P, Carroll K, Ahlsen G, Bahna F, Vendome J, Posy S, Rajebhosale M, Price S, Jessell TM, Ben-Shaul A, Shapiro L, Honig BH.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11594-9. doi: 10.1073/pnas.0905349106. Epub 2009 Jun 24.

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