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Effect of salt supplementation on sympathetic activity and endothelial function in salt sensitive type 2 diabetes.

Baqar S, Kong YW, Chen AX, O'callaghan C, Macisaac RJ, Bouterakos M, Lambert GW, Jerums G, Lambert EE, Ekinci EI.

J Clin Endocrinol Metab. 2019 Nov 25. pii: dgz219. doi: 10.1210/clinem/dgz219. [Epub ahead of print]


Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions.

Torkamani N, Churilov L, Robbins R, Jerums G, Beik V, Radcliffe N, Patterson S, Bellomo R, Burns J, Hart GK, Lam Q, Power DA, MacIsaac RJ, Johnson DF, Zajac J, Ekinci EI.

J Diabetes Complications. 2020 Jan;34(1):107465. doi: 10.1016/j.jdiacomp.2019.107465. Epub 2019 Oct 22.


Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.

Chen AX, Moran JL, Libianto R, Baqar S, O'Callaghan C, MacIsaac RJ, Jerums G, Ekinci EI.

J Hum Hypertens. 2019 Sep 9. doi: 10.1038/s41371-019-0238-3. [Epub ahead of print]


Comparison of endothelial function and sympathetic nervous system activity along the glucose continuum in individuals with differing metabolic risk profiles and low dietary sodium intake.

Baqar S, Straznicky NE, Lambert G, Kong YW, Dixon JB, Jerums G, Ekinci EI, Lambert E.

BMJ Open Diabetes Res Care. 2019 Mar 25;7(1):e000606. doi: 10.1136/bmjdrc-2018-000606. eCollection 2019.


Changes in soluble tumor necrosis factor receptor type 1 levels and early renal function decline in patients with diabetes.

MacIsaac RJ, Farag M, Obeyesekere V, Clarke M, Boston R, Ward GM, Jerums G, Ekinci EI.

J Diabetes Investig. 2019 Nov;10(6):1537-1542. doi: 10.1111/jdi.13061. Epub 2019 Jun 3.


Is hyperfiltration associated with higher urine albumin-to-creatinine ratio at follow up among Indigenous Australians? The eGFR follow-up study.

Ekinci EI, Barr ELM, Barzi F, Hughes JT, Lawton PD, Jones GRD, Hoy W, Cass A, Thomas M, Sinha A, Jerums G, O'Dea K, MacIsaac RJ, Maple-Brown LJ.

J Diabetes Complications. 2019 May;33(5):343-349. doi: 10.1016/j.jdiacomp.2019.02.005. Epub 2019 Feb 21.


Three Dimensional Glomerular Reconstruction: A Novel Approach to Evaluate Renal Microanatomy in Diabetic Kidney Disease.

Torkamani N, Jerums G, Crammer P, Skene A, Power DA, Panagiotopoulos S, Clarke M, MacIsaac RJ, Ekinci EI.

Sci Rep. 2019 Feb 12;9(1):1829. doi: 10.1038/s41598-019-38646-z.


The relationship between habitual dietary sodium intake and RAAS blockade on circulating microparticle levels in type two diabetes.

Baqar S, Liu D, Lincz LF, Kong YW, Jerums G, Ekinci EI.

Clin Sci (Lond). 2018 Oct 22;132(20):2207-2220. doi: 10.1042/CS20180472. Print 2018 Oct 31.


Use of Readily Accessible Inflammatory Markers to Predict Diabetic Kidney Disease.

Winter L, Wong LA, Jerums G, Seah JM, Clarke M, Tan SM, Coughlan MT, MacIsaac RJ, Ekinci EI.

Front Endocrinol (Lausanne). 2018 May 22;9:225. doi: 10.3389/fendo.2018.00225. eCollection 2018. Review.


Glycemic Control as Primary Prevention for Diabetic Kidney Disease.

MacIsaac RJ, Jerums G, Ekinci EI.

Adv Chronic Kidney Dis. 2018 Mar;25(2):141-148. doi: 10.1053/j.ackd.2017.11.003. Review.


High Baseline Levels of Tumor Necrosis Factor Receptor 1 Are Associated With Progression of Kidney Disease in Indigenous Australians With Diabetes: The eGFR Follow-up Study.

Barr ELM, Barzi F, Hughes JT, Jerums G, Hoy WE, O'Dea K, Jones GRD, Lawton PD, Brown ADH, Thomas M, Ekinci EI, Sinha A, Cass A, MacIsaac RJ, Maple-Brown LJ.

Diabetes Care. 2018 Apr;41(4):739-747. doi: 10.2337/dc17-1919. Epub 2018 Jan 24.


Trajectories of eGFR decline over a four year period in an Indigenous Australian population at high risk of CKD-the eGFR follow up study.

Barzi F, Jones GRD, Hughes JT, Lawton PD, Hoy W, O'Dea K, Jerums G, MacIsaac RJ, Cass A, Maple-Brown LJ.

Clin Biochem. 2018 Mar;53:58-64. doi: 10.1016/j.clinbiochem.2018.01.011.


Cross-sectional associations of albuminuria among Aboriginal and Torres Strait Islander adults: the eGFR Study.

Hughes JT, Maple-Brown LJ, Thomas M, Lawton PD, Sinha A, Cass A, Barzi F, Jones G, Jerums G, MacIsaac RJ, O'Dea K, Hoy WE.

Nephrology (Carlton). 2018 Jan;23(1):37-45. doi: 10.1111/nep.12956.


Long-term intra-individual variability of albuminuria in type 2 diabetes mellitus: implications for categorization of albumin excretion rate.

Leong A, Ekinci EI, Nguyen C, Milne M, Hachem M, Dobson M, MacIsaac RJ, Jerums G.

BMC Nephrol. 2017 Dec 6;18(1):355. doi: 10.1186/s12882-017-0767-3.


Relationship between urinary sodium-to-potassium ratio and ambulatory blood pressure in patients with diabetes mellitus.

Libianto R, Moran J, O'Callaghan C, Baqar S, Chen AX, Baker ST, Clarke M, MacIsaac RJ, Jerums G, Ekinci EI.

Clin Exp Pharmacol Physiol. 2018 Jan;45(1):94-97. doi: 10.1111/1440-1681.12852. Epub 2017 Oct 25.


Effects of glycaemic management on diabetic kidney disease.

MacIsaac RJ, Jerums G, Ekinci EI.

World J Diabetes. 2017 May 15;8(5):172-186. doi: 10.4239/wjd.v8.i5.172. Review.


Contribution of cardiometabolic risk factors to estimated glomerular filtration rate decline in Indigenous Australians with and without albuminuria - the eGFR Follow-up Study.

Barr EL, Barzi F, Hughes JT, Jerums G, O'Dea K, Brown AD, Ekinci EI, Jones GR, Lawton PD, Sinha A, MacIsaac RJ, Cass A, Maple-Brown LJ.

Nephrology (Carlton). 2018 Jul;23(7):682-689. doi: 10.1111/nep.13073.


Sodium and Its Role in Cardiovascular Disease - The Debate Continues.

Kong YW, Baqar S, Jerums G, Ekinci EI.

Front Endocrinol (Lausanne). 2016 Dec 23;7:164. doi: 10.3389/fendo.2016.00164. eCollection 2016. Review.


Comparison of creatinine and cystatin C based eGFR in the estimation of glomerular filtration rate in Indigenous Australians: The eGFR Study.

Barr EL, Maple-Brown LJ, Barzi F, Hughes JT, Jerums G, Ekinci EI, Ellis AG, Jones GR, Lawton PD, Sajiv C, Majoni SW, Brown AD, Hoy WE, O'Dea K, Cass A, MacIsaac RJ.

Clin Biochem. 2017 Apr;50(6):301-308. doi: 10.1016/j.clinbiochem.2016.11.024. Epub 2016 Nov 25.


Cardio-renal protection with empagliflozin.

MacIsaac RJ, Jerums G, Ekinci EI.

Ann Transl Med. 2016 Oct;4(20):409.


A Single Dose of Prednisolone as a Modulator of Undercarboxylated Osteocalcin and Insulin Sensitivity Post-Exercise in Healthy Young Men: A Study Protocol.

Levinger I, Brennan-Speranza TC, Stepto NK, Jerums G, Parker L, McConell GK, Anderson M, Garnham A, Hare DL, Ebeling PR, Seeman E.

JMIR Res Protoc. 2016 Jun 3;5(2):e78. doi: 10.2196/resprot.5119.


Assessing the Value of BMI and Aerobic Capacity as Surrogate Markers for the Severity of Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes Who Are Obese.

Smith C, Asrar Ul Haq M, Jerums G, Hanson E, Hayes A, Allen JD, Sbaraglia M, Selig S, Wong C, Hare DL, Levinger I.

Clin Med Insights Cardiol. 2016 May 12;10:61-5. doi: 10.4137/CMC.S38116. eCollection 2016.


Clinical predictive factors in diabetic kidney disease progression.

Radcliffe NJ, Seah JM, Clarke M, MacIsaac RJ, Jerums G, Ekinci EI.

J Diabetes Investig. 2017 Jan;8(1):6-18. doi: 10.1111/jdi.12533. Epub 2016 Jun 8. Review.


Progression of Kidney Disease in Indigenous Australians: The eGFR Follow-up Study.

Maple-Brown LJ, Hughes JT, Ritte R, Barzi F, Hoy WE, Lawton PD, Jones GR, Death E, Simmonds A, Sinha AK, Cherian S, Thomas MA, McDermott R, Brown AD, O'Dea K, Jerums G, Cass A, MacIsaac RJ.

Clin J Am Soc Nephrol. 2016 Jun 6;11(6):993-1004. doi: 10.2215/CJN.09770915. Epub 2016 Apr 13.


Muscle atrophy in patients with Type 2 Diabetes Mellitus: roles of inflammatory pathways, physical activity and exercise.

Perry BD, Caldow MK, Brennan-Speranza TC, Sbaraglia M, Jerums G, Garnham A, Wong C, Levinger P, Asrar Ul Haq M, Hare DL, Price SR, Levinger I.

Exerc Immunol Rev. 2016;22:94-109. Review.


Glucose-loading reduces bone remodeling in women and osteoblast function in vitro.

Levinger I, Seeman E, Jerums G, McConell GK, Rybchyn MS, Cassar S, Byrnes E, Selig S, Mason RS, Ebeling PR, Brennan-Speranza TC.

Physiol Rep. 2016 Feb;4(3). pii: e12700. doi: 10.14814/phy2.12700. Epub 2016 Feb 4.


Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.

Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM.

Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28.


Elevated baseline glomerular filtration rate (GFR) is independently associated with a more rapid decline in renal function of patients with type 1 diabetes.

Thomson HJ, Ekinci EI, Radcliffe NJ, Seah JM, MacIsaac RJ, Jerums G, Premaratne E.

J Diabetes Complications. 2016 Mar;30(2):256-61. doi: 10.1016/j.jdiacomp.2015.11.003. Epub 2015 Nov 11.


The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation does not improve the underestimation of Glomerular Filtration Rate (GFR) in people with diabetes and preserved renal function.

MacIsaac RJ, Ekinci EI, Premaratne E, Lu ZX, Seah JM, Li Y, Boston R, Ward GM, Jerums G.

BMC Nephrol. 2015 Dec 3;16:198. doi: 10.1186/s12882-015-0196-0.


Estimating glomerular filtration rate: Performance of the CKD-EPI equation over time in patients with type 2 diabetes.

Wood AJ, Churilov L, Perera N, Thomas D, Poon A, MacIsaac RJ, Jerums G, Ekinci EI.

J Diabetes Complications. 2016 Jan-Feb;30(1):49-54. doi: 10.1016/j.jdiacomp.2015.08.025. Epub 2015 Sep 8.


Association of sex hormone-binding globulin and free testosterone with mortality in men with type 2 diabetes mellitus.

Tint AN, Hoermann R, Wong H, Ekinci EI, MacIsaac RJ, Jerums G, Zajac JD, Grossmann M.

Eur J Endocrinol. 2016 Jan;174(1):59-68. doi: 10.1530/EJE-15-0672. Epub 2015 Oct 19.


The effect of hyperinsulinaemic-euglycaemic clamp and exercise on bone remodeling markers in obese men.

Levinger I, Brennan-Speranza TC, Jerums G, Stepto NK, Serpiello FR, McConell GK, Anderson M, Hare DL, Byrnes E, Ebeling PR, Seeman E.

Bonekey Rep. 2015 Aug 26;4:731. doi: 10.1038/bonekey.2015.100. eCollection 2015.


The effects of muscle contraction and recombinant osteocalcin on insulin sensitivity ex vivo.

Levinger I, Lin X, Zhang X, Brennan-Speranza TC, Volpato B, Hayes A, Jerums G, Seeman E, McConell G.

Osteoporos Int. 2016 Feb;27(2):653-63. doi: 10.1007/s00198-015-3273-0. Epub 2015 Aug 11.


Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events in Diabetic Nephropathy?

Sourris KC, Yao H, Jerums G, Cooper ME, Ekinci EI, Coughlan MT.

Curr Drug Targets. 2016;17(11):1252-64. Review.


Hyperfiltration in Indigenous Australians with and without diabetes.

Ekinci EI, Hughes JT, Chatfield MD, Lawton PD, Jones GR, Ellis AG, Cass A, Thomas M, MacIsaac RJ, O'Dea K, Jerums G, Maple-Brown LJ.

Nephrol Dial Transplant. 2015 Nov;30(11):1877-84. doi: 10.1093/ndt/gfv230. Epub 2015 Jul 3.


Short-term dietary salt supplementation blunts telmisartan induced increases in plasma renin activity in hypertensive patients with type 2 diabetes mellitus.

Chen AX, Jerums G, Baqar S, Lambert E, Somarajah G, Thomas G, O'Callaghan C, MacIsaac RJ, Ekinci EI.

Clin Sci (Lond). 2015 Sep;129(5):415-22. doi: 10.1042/CS20140536. Epub 2015 Apr 7.


Diabetic nephropathy: How does exercise affect kidney disease in T1DM?

Jerums G, MacIsaac RJ.

Nat Rev Endocrinol. 2015 Jun;11(6):324-5. doi: 10.1038/nrendo.2015.46. Epub 2015 Mar 17. No abstract available.


Adding measures of body composition to the CKD-EPI GFR estimating equation in Indigenous Australians: the eGFR study.

Maple-Brown LJ, Hughes JT, Chatfield MD, Ward LC, Piers LS, Jones GR, Lawton PD, Ellis AG, Cass A, Hoy WE, O'Dea K, MacIsaac RJ, Jerums G.

Am J Kidney Dis. 2015 Apr;65(4):632-4. doi: 10.1053/j.ajkd.2014.11.015. Epub 2015 Jan 22. No abstract available.


Cardiovascular outcomes with antihypertensive therapy in type 2 diabetes: an analysis of intervention trials.

Jerums G, Panagiotopoulos S, Ekinci E, MacIsaac RJ.

J Hum Hypertens. 2015 Aug;29(8):473-7. doi: 10.1038/jhh.2014.117. Epub 2015 Jan 22.


Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides.

Schanstra JP, Zürbig P, Alkhalaf A, Argiles A, Bakker SJ, Beige J, Bilo HJ, Chatzikyrkou C, Dakna M, Dawson J, Delles C, Haller H, Haubitz M, Husi H, Jankowski J, Jerums G, Kleefstra N, Kuznetsova T, Maahs DM, Menne J, Mullen W, Ortiz A, Persson F, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Siwy J, Snell-Bergeon J, Spasovski G, Staessen JA, Vlahou A, Mischak H, Vanholder R.

J Am Soc Nephrol. 2015 Aug;26(8):1999-2010. doi: 10.1681/ASN.2014050423. Epub 2015 Jan 14.


The impact of hyperfiltration on the diabetic kidney.

Premaratne E, Verma S, Ekinci EI, Theverkalam G, Jerums G, MacIsaac RJ.

Diabetes Metab. 2015 Feb;41(1):5-17. doi: 10.1016/j.diabet.2014.10.003. Epub 2014 Nov 18. Review.


Serum vitamin D levels, diabetes and cardio-metabolic risk factors in Aboriginal and Torres Strait Islander Australians.

Maple-Brown LJ, Hughes JT, Lu ZX, Jeyaraman K, Lawton P, Jones GR, Ellis A, Sinha A, Cass A, MacIsaac RJ, Jerums G, O'Dea K.

Diabetol Metab Syndr. 2014 Jul 16;6:78. doi: 10.1186/1758-5996-6-78. eCollection 2014.


Spectrum of renal disease in diabetes.

Teng J, Dwyer KM, Hill P, See E, Ekinci EI, Jerums G, MacIsaac RJ.

Nephrology (Carlton). 2014 Sep;19(9):528-36. doi: 10.1111/nep.12288. Review.


Diabetes: Predicting renal function decline in patients with T2DM.

Jerums G, MacIsaac RJ.

Nat Rev Endocrinol. 2014 Jul;10(7):381-2. doi: 10.1038/nrendo.2014.75. Epub 2014 May 27. No abstract available.


The effect of acute exercise on undercarboxylated osteocalcin and insulin sensitivity in obese men.

Levinger I, Jerums G, Stepto NK, Parker L, Serpiello FR, McConell GK, Anderson M, Hare DL, Byrnes E, Ebeling PR, Seeman E.

J Bone Miner Res. 2014 Dec;29(12):2571-6. doi: 10.1002/jbmr.2285.


'Progressive diabetic nephropathy. How useful is microalbuminuria?: contra'.

MacIsaac RJ, Ekinci EI, Jerums G.

Kidney Int. 2014 Jul;86(1):50-7. doi: 10.1038/ki.2014.98. Epub 2014 Apr 9. Review.


Effect of exercise training on left ventricular remodeling in diabetic patients with diastolic dysfunction: rationale and design.

Asrar Ul Haq M, Wong C, Levinger I, Srivastava PM, Sbaraglia M, Toia D, Jerums G, Selig S, Hare DL.

Clin Med Insights Cardiol. 2014 Mar 10;8:23-8. doi: 10.4137/CMC.S14089. eCollection 2014.


Relationship between urinary sodium excretion over time and mortality in type 2 diabetes.

Ekinci EI, Moran JL, Thomas MC, Cheong K, Clarke S, Chen A, Dobson M, Leong A, Macisaac RJ, Jerums G.

Diabetes Care. 2014 Apr;37(4):e62-3. doi: 10.2337/dc13-1947. No abstract available.


Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study.

Maple-Brown LJ, Ekinci EI, Hughes JT, Chatfield M, Lawton PD, Jones GR, Ellis AG, Sinha A, Cass A, Hoy WE, O'Dea K, Jerums G, MacIsaac RJ; investigators of the eGFR Study.

Diabet Med. 2014 Jul;31(7):829-38. doi: 10.1111/dme.12426. Epub 2014 Apr 4.


Markers of and risk factors for the development and progression of diabetic kidney disease.

Macisaac RJ, Ekinci EI, Jerums G.

Am J Kidney Dis. 2014 Feb;63(2 Suppl 2):S39-62. doi: 10.1053/j.ajkd.2013.10.048. Review.


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