Jerome Eeckhoute[author] - PubMed

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Select item 302170951.

Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response.

Bobowski-Gerard M, Zummo FP, Staels B, Lefebvre P, Eeckhoute J.

Cells. 2018 Sep 13;7(9). pii: E137. doi: 10.3390/cells7090137.

PMID:: 30217095

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Select item 299814272.

The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis.

Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P.

J Hepatol. 2018 Jul 5. pii: S0168-8278(18)32175-5. doi: 10.1016/j.jhep.2018.06.022. [Epub ahead of print]

PMID:: 29981427

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Select item 292958603.

Reduced PPARγ2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modifications.

Lecoutre S, Pourpe C, Butruille L, Marousez L, Laborie C, Guinez C, Lesage J, Vieau D, Eeckhoute J, Gabory A, Oger F, Eberlé D, Breton C.

FASEB J. 2018 May;32(5):2768-2778. doi: 10.1096/fj.201700997R. Epub 2018 Jan 8.

PMID:: 29295860

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Select item 292775614.

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.

Pourcet B, Zecchin M, Ferri L, Beauchamp J, Sitaula S, Billon C, Delhaye S, Vanhoutte J, Mayeuf-Louchart A, Thorel Q, Haas JT, Eeckhoute J, Dombrowicz D, Duhem C, Boulinguiez A, Lancel S, Sebti Y, Burris TP, Staels B, Duez HM.

Gastroenterology. 2018 Apr;154(5):1449-1464.e20. doi: 10.1053/j.gastro.2017.12.019. Epub 2017 Dec 24.

PMID:: 29277561

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Select item 291073245.

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.

Montaigne D, Marechal X, Modine T, Coisne A, Mouton S, Fayad G, Ninni S, Klein C, Ortmans S, Seunes C, Potelle C, Berthier A, Gheeraert C, Piveteau C, Deprez R, Eeckhoute J, Duez H, Lacroix D, Deprez B, Jegou B, Koussa M, Edme JL, Lefebvre P, Staels B.

Lancet. 2018 Jan 6;391(10115):59-69. doi: 10.1016/S0140-6736(17)32132-3. Epub 2017 Oct 26.

PMID:: 29107324

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Select item 291055386.

Organizing combinatorial transcription factor recruitment at cis-regulatory modules.

Dubois-Chevalier J, Mazrooei P, Lupien M, Staels B, Lefebvre P, Eeckhoute J.

Transcription. 2018;9(4):233-239. doi: 10.1080/21541264.2017.1394424. Epub 2017 Nov 28.

PMID:: 29105538

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Select item 290750207.

The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.

Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, Venteclef N, Pattou F, Staels B, Eeckhoute J, Lefebvre P.

Sci Rep. 2017 Oct 26;7(1):14087. doi: 10.1038/s41598-017-14570-y.

PMID:: 29075020

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Select item 287520558.

Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner.

Lecoutre S, Oger F, Pourpe C, Butruille L, Marousez L, Dickes-Coopman A, Laborie C, Guinez C, Lesage J, Vieau D, Junien C, Eberlé D, Gabory A, Eeckhoute J, Breton C.

Mol Metab. 2017 May 31;6(8):922-930. doi: 10.1016/j.molmet.2017.05.010. eCollection 2017 Aug.

PMID:: 28752055

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Select item 286799479.

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.

Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, Vonghia L, Kwanten WJ, Michielsen P, Vanwolleghem T, Eeckhoute J, Verrijken A, Van Gaal L, Francque S, Staels B.

JCI Insight. 2017 Jul 6;2(13). pii: 92264. doi: 10.1172/jci.insight.92264. [Epub ahead of print]

PMID:: 28679947

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Select item 2843877910.

Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity.

Chinetti-Gbaguidi G, Daoudi M, Rosa M, Vinod M, Louvet L, Copin C, Fanchon M, Vanhoutte J, Derudas B, Belloy L, Haulon S, Zawadzki C, Susen S, Massy ZA, Eeckhoute J, Staels B.

Circ Res. 2017 Jun 23;121(1):19-30. doi: 10.1161/CIRCRESAHA.116.310262. Epub 2017 Apr 24.

PMID:: 28438779

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Select item 2840042511.

The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.

Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Guillaume P, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, Staels B, Lefebvre P, Eeckhoute J.

Genome Res. 2017 Jun;27(6):985-996. doi: 10.1101/gr.217075.116. Epub 2017 Apr 11.

PMID:: 28400425

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Select item 2836828612.

Distinct but complementary contributions of PPAR isotypes to energy homeostasis.

Dubois V, Eeckhoute J, Lefebvre P, Staels B.

J Clin Invest. 2017 Apr 3;127(4):1202-1214. doi: 10.1172/JCI88894. Epub 2017 Apr 3. Review.

PMID:: 28368286

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Select item 2805949913.

Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.

Le Guével R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G.

ACS Chem Biol. 2017 Mar 17;12(3):654-663. doi: 10.1021/acschembio.6b00593. Epub 2017 Jan 13.

PMID:: 28059499

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Select item 2676312714.

Transducin-like enhancer of split-1 is expressed and functional in human macrophages.

De Paoli F, Copin C, Vanhoutte J, Derudas B, Vinod M, Zawadzki C, Susen S, Pattou F, Haulon S, Staels B, Eeckhoute J, Chinetti-Gbaguidi G.

FEBS Lett. 2016 Jan;590(1):43-52. doi: 10.1002/1873-3468.12029. Epub 2015 Dec 30.

PMID:: 26763127

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Select item 2556541315.

The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation.

Dubois-Chevalier J, Staels B, Lefebvre P, Eeckhoute J.

Nucleus. 2015;6(1):15-8. doi: 10.1080/19491034.2015.1004258. Review.

PMID:: 25565413

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Select item 2518352516.

A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation.

Dubois-Chevalier J, Oger F, Dehondt H, Firmin FF, Gheeraert C, Staels B, Lefebvre P, Eeckhoute J.

Nucleic Acids Res. 2014;42(17):10943-59. doi: 10.1093/nar/gku780. Epub 2014 Sep 2.

PMID:: 25183525

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Select item 2475818417.

Cell-specific dysregulation of microRNA expression in obese white adipose tissue.

Oger F, Gheeraert C, Mogilenko D, Benomar Y, Molendi-Coste O, Bouchaert E, Caron S, Dombrowicz D, Pattou F, Duez H, Eeckhoute J, Staels B, Lefebvre P.

J Clin Endocrinol Metab. 2014 Aug;99(8):2821-33. doi: 10.1210/jc.2013-4259. Epub 2014 Apr 23.

PMID:: 24758184

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Select item 2475289518.

Dynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities.

Quintin J, Le Péron C, Palierne G, Bizot M, Cunha S, Sérandour AA, Avner S, Henry C, Percevault F, Belaud-Rotureau MA, Huet S, Watrin E, Eeckhoute J, Legagneux V, Salbert G, Métivier R.

Mol Cell Biol. 2014 Jul;34(13):2418-36. doi: 10.1128/MCB.00918-13. Epub 2014 Apr 21.