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Items: 1 to 50 of 179

1.

Investigation of nonalcoholic fatty liver disease-induced drug metabolism by comparative global toxicoproteomics.

Na AY, Jo JJ, Kwon OK, Shrestha R, Cho PJ, Kim KM, Ki SH, Lee TH, Jeon TW, Jeong TC, Lee S.

Toxicol Appl Pharmacol. 2018 Aug 1;352:28-37. doi: 10.1016/j.taap.2018.05.021. Epub 2018 May 21.

PMID:
29792946
2.

Ameliorating effect of TI-1-162, a hydroxyindenone derivative, against TNBS-induced rat colitis is mediated through suppression of RIP/ASK-1/MAPK signaling.

Gurung P, Banskota S, Katila N, Gautam J, Kadayat TM, Choi DY, Lee ES, Jeong TC, Kim JA.

Eur J Pharmacol. 2018 May 15;827:94-102. doi: 10.1016/j.ejphar.2018.03.027. Epub 2018 Mar 16.

PMID:
29555502
3.

A simple in chemico method for testing skin sensitizing potential of chemicals using small endogenous molecules.

Nepal MR, Shakya R, Kang MJ, Jeong TC.

Toxicol Lett. 2018 Jun 1;289:75-85. doi: 10.1016/j.toxlet.2018.03.006. Epub 2018 Mar 12.

PMID:
29545173
4.

A β-galactosidase-expressing E. coli culture as an alternative test to identify skin sensitizers and non-sensitizers.

Nepal MR, Kang Y, Kang MJ, Nam DH, Jeong TC.

J Toxicol Environ Health A. 2018;81(9):288-301. doi: 10.1080/15287394.2018.1440187. Epub 2018 Feb 23.

PMID:
29473800
5.

Impact of gut microbiota on drug metabolism: an update for safe and effective use of drugs.

Noh K, Kang YR, Nepal MR, Shakya R, Kang MJ, Kang W, Lee S, Jeong HG, Jeong TC.

Arch Pharm Res. 2017 Dec;40(12):1345-1355. doi: 10.1007/s12272-017-0986-y. Epub 2017 Nov 27. Review.

PMID:
29181640
6.

Intra- and inter-laboratory reproducibility and predictivity of the HaCaSens assay: A skin sensitization test using human keratinocytes, HaCaT.

Chung H, Quan H, Jung D, Ravi G, Cho A, Kang MJ, Kim E, Che JH, Lee ES, Jeong TC, Heo Y, Seok SH.

Toxicol In Vitro. 2018 Feb;46:304-312. doi: 10.1016/j.tiv.2017.10.018. Epub 2017 Oct 18.

PMID:
29054701
7.

Phase I and phase II metabolite identification of rutaecarpine in freshly isolated hepatocytes from male Sprague-Dawley rats.

Lee DW, Kang Y, Kang MJ, Noh K, Kim JH, Nepal MR, Shakya R, Lee YJ, Jahng Y, Lee S, Kim JA, Jeong TC.

Arch Pharm Res. 2017 Aug;40(8):972-979. doi: 10.1007/s12272-017-0937-7. Epub 2017 Aug 10.

PMID:
28799086
8.

Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells.

Kim HG, Jin SW, Kim YA, Khanal T, Lee GH, Kim SJ, Rhee SD, Chung YC, Hwang YJ, Jeong TC, Jeong HG.

Food Chem Toxicol. 2017 Aug;106(Pt A):232-241. doi: 10.1016/j.fct.2017.05.058. Epub 2017 May 29.

PMID:
28571770
9.

Investigation of the Regulatory Effects of Saccharin on Cytochrome P450s in Male ICR Mice.

Jo JH, Kim S, Jeon TW, Jeong TC, Lee S.

Toxicol Res. 2017 Jan;33(1):25-30. doi: 10.5487/TR.2017.33.1.025. Epub 2017 Jan 15.

10.

Protective effect of rutaecarpine against t-BHP-induced hepatotoxicity by upregulating antioxidant enzymes via the CaMKII-Akt and Nrf2/ARE pathways.

Jin SW, Hwang YP, Choi CY, Kim HG, Kim SJ, Kim Y, Chung YC, Lee KJ, Jeong TC, Jeong HG.

Food Chem Toxicol. 2017 Feb;100:138-148. doi: 10.1016/j.fct.2016.12.031. Epub 2016 Dec 23.

PMID:
28025122
11.

Identification and quantification of myosin heavy chain isoforms in bovine and porcine longissimus muscles by LC-MS/MS analysis.

Kim GD, Jeong TC, Cho KM, Jeong JY.

Meat Sci. 2017 Mar;125:143-151. doi: 10.1016/j.meatsci.2016.12.002. Epub 2016 Dec 7.

PMID:
27960114
12.

Prevalidation trial for a novel in vitro eye irritation test using the reconstructed human cornea-like epithelial model, MCTT HCE™.

Yang H, Kim DE, Jang WH, An S, Cho SA, Jung MS, Lee JE, Yeo KW, Koh SB, Jeong TC, Kang MJ, Chun YJ, Lee SH, Lim KM, Bae S.

Toxicol In Vitro. 2017 Mar;39:58-67. doi: 10.1016/j.tiv.2016.11.010. Epub 2016 Nov 19.

PMID:
27876558
13.

Performance standard-based validation study for local lymph node assay: 5-bromo-2-deoxyuridine-flow cytometry method.

Ahn I, Kim TS, Jung ES, Yi JS, Jang WH, Jung KM, Park M, Jung MS, Jeon EY, Yeo KU, Jo JH, Park JE, Kim CY, Park YC, Seong WK, Lee AY, Chun YJ, Jeong TC, Jeung EB, Lim KM, Bae S, Sohn S, Heo Y.

Regul Toxicol Pharmacol. 2016 Oct;80:183-94. doi: 10.1016/j.yrtph.2016.06.009. Epub 2016 Jun 16.

PMID:
27318101
14.

Analysis of Methionine Oxidation in Myosin Isoforms in Porcine Skeletal Muscle by LC-MS/MS Analysis.

Jeong JY, Jung EY, Jeong TC, Yang HS, Kim GD.

Korean J Food Sci Anim Resour. 2016;36(2):254-61. doi: 10.5851/kosfa.2016.36.2.254. Epub 2016 Apr 30.

15.

Pharmacokinetic Interaction of Chrysin with Caffeine in Rats.

Noh K, Oh do G, Nepal MR, Jeong KS, Choi Y, Kang MJ, Kang W, Jeong HG, Jeong TC.

Biomol Ther (Seoul). 2016 Jul 1;24(4):446-52. doi: 10.4062/biomolther.2015.197. Epub 2016 Apr 25.

16.

Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics.

Noh K, Kang Y, Nepal MR, Jeong KS, Oh DG, Kang MJ, Lee S, Kang W, Jeong HG, Jeong TC.

Molecules. 2016 Mar 10;21(3):337. doi: 10.3390/molecules21030337. Review.

17.

Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.

Yang Y, Nguyen TT, Jeong MH, Crişan F, Yu YH, Ha HH, Choi KH, Jeong HG, Jeong TC, Lee KY, Kim KK, Hur JS, Kim H.

PLoS One. 2016 Jan 11;11(1):e0146575. doi: 10.1371/journal.pone.0146575. eCollection 2016.

18.

Betulinic Acid Increases eNOS Phosphorylation and NO Synthesis via the Calcium-Signaling Pathway.

Jin SW, Choi CY, Hwang YP, Kim HG, Kim SJ, Chung YC, Lee KJ, Jeong TC, Jeong HG.

J Agric Food Chem. 2016 Feb 3;64(4):785-91. doi: 10.1021/acs.jafc.5b05416. Epub 2016 Jan 25.

PMID:
26750873
19.

Predictive capacity of a non-radioisotopic local lymph node assay using flow cytometry, LLNA:BrdU-FCM: Comparison of a cutoff approach and inferential statistics.

Kim DE, Yang H, Jang WH, Jung KM, Park M, Choi JK, Jung MS, Jeon EY, Heo Y, Yeo KW, Jo JH, Park JE, Sohn SJ, Kim TS, Ahn IY, Jeong TC, Lim KM, Bae S.

J Pharmacol Toxicol Methods. 2016 Mar-Apr;78:76-84. doi: 10.1016/j.vascn.2015.12.001. Epub 2015 Dec 4.

PMID:
26654807
20.

Comprehensive Analysis of in Vivo Phosphoproteome of Mouse Liver Microsomes.

Kwon OK, Sim J, Kim SJ, Sung E, Kim JY, Jeong TC, Lee S.

J Proteome Res. 2015 Dec 4;14(12):5215-24. doi: 10.1021/acs.jproteome.5b00812. Epub 2015 Oct 30.

PMID:
26487105
21.

Characterization of novel mechanisms for steatosis from global protein hyperacetylation in ethanol-induced mouse hepatocytes.

Kim SJ, Kwon OK, Ki SH, Jeong TC, Lee S.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):832-8. doi: 10.1016/j.bbrc.2015.04.154. Epub 2015 Jun 6.

PMID:
26056001
22.

Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation.

Han JY, Lee S, Yang JH, Kim S, Sim J, Kim MG, Jeong TC, Ku SK, Cho IJ, Ki SH.

J Ginseng Res. 2015 Apr;39(2):105-15. doi: 10.1016/j.jgr.2014.09.001. Epub 2014 Sep 6.

23.

Effects of baicalin on oral pharmacokinetics of caffeine in rats.

Noh K, Nepal MR, Jeong KS, Kim SA, Um YJ, Seo CS, Kang MJ, Park PH, Kang W, Jeong HG, Jeong TC.

Biomol Ther (Seoul). 2015 Mar;23(2):201-6. doi: 10.4062/biomolther.2014.134. Epub 2015 Mar 1.

24.

Inhibitory Effect of 3-(4-Hydroxyphenyl)-1-(thiophen-2-yl) prop-2-en-1-one, a Chalcone Derivative on MCP-1 Expression in Macrophages via Inhibition of ROS and Akt Signaling.

Kim MJ, Kadayat T, Um YJ, Jeong TC, Lee ES, Park PH.

Biomol Ther (Seoul). 2015 Mar;23(2):119-27. doi: 10.4062/biomolther.2014.127. Epub 2015 Mar 1.

25.

Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.

Bae ON, Ahn S, Jin SH, Hong SH, Lee J, Kim ES, Jeong TC, Chun YJ, Lee AY, Noh M.

Toxicol Appl Pharmacol. 2015 Mar 1;283(2):147-55. doi: 10.1016/j.taap.2015.01.008. Epub 2015 Jan 21.

PMID:
25617811
26.

Keratinocytic vascular endothelial growth factor as a novel biomarker for pathological skin condition.

Bae ON, Noh M, Chun YJ, Jeong TC.

Biomol Ther (Seoul). 2015 Jan;23(1):12-8. doi: 10.4062/biomolther.2014.102. Epub 2015 Jan 1. Review.

27.

Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells.

Choi JH, Jin SW, Kim HG, Choi CY, Lee HS, Ryu SY, Chung YC, Hwang YJ, Um YJ, Jeong TC, Jeong HG.

J Agric Food Chem. 2015 Feb 11;63(5):1468-76. doi: 10.1021/jf5043954. Epub 2015 Jan 29.

PMID:
25590691
28.

Evaluation of cadmium-induced nephrotoxicity using urinary metabolomic profiles in sprague-dawley male rats.

Lee YK, Park EY, Kim S, Son JY, Kim TH, Kang WG, Jeong TC, Kim KB, Kwack SJ, Lee J, Kim S, Lee BM, Kim HS.

J Toxicol Environ Health A. 2014;77(22-24):1384-98. doi: 10.1080/15287394.2014.951755.

PMID:
25343288
29.

Nephrotoxic potential and toxicokinetics of melamine combined with cyanuric acid in rats.

Kim GH, Kang MJ, Noh K, Oh DG, Kang W, Jeong HG, Lee KY, Kim H, Kim HS, Jeong TC.

J Toxicol Environ Health A. 2014;77(22-24):1346-58. doi: 10.1080/15287394.2014.951592.

PMID:
25343285
30.

Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression.

Do MT, Kim HG, Tran TT, Khanal T, Choi JH, Chung YC, Jeong TC, Jeong HG.

Toxicol Appl Pharmacol. 2014 Oct 1;280(1):138-48. doi: 10.1016/j.taap.2014.07.021. Epub 2014 Aug 7.

PMID:
25110054
31.

Evaluation of renal toxicity by combination exposure to melamine and cyanuric Acid in male sprague-dawley rats.

Son JY, Kang YJ, Kim KS, Kim TH, Lim SK, Lim HJ, Jeong TC, Choi DW, Chung KH, Lee BM, Kim HS.

Toxicol Res. 2014 Jun;30(2):99-107.

32.

Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer.

Sim J, Nam W, Lee D, Lee S, O H, Joo J, Liu KH, Han JY, Ki SH, Jeong TC, Lee T, Lee S.

Arch Pharm Res. 2015;38(5):725-33. doi: 10.1007/s12272-014-0443-0. Epub 2014 Jul 23.

PMID:
25052955
33.

Comparison of live performance and meat quality parameter of cross bred (korean native black pig and landrace) pigs with different coat colors.

Hur SJ, Jeong TC, Kim GD, Jeong JY, Cho IC, Lim HT, Kim BW, Joo ST.

Asian-Australas J Anim Sci. 2013 Jul;26(7):1047-53. doi: 10.5713/ajas.2013.13005.

34.

Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.

Do MT, Na M, Kim HG, Khanal T, Choi JH, Jin SW, Oh SH, Hwang IH, Chung YC, Kim HS, Jeong TC, Jeong HG.

Food Chem Toxicol. 2014 Sep;71:51-9. doi: 10.1016/j.fct.2014.06.001. Epub 2014 Jun 12.

PMID:
24930757
35.

Protein kinase a phosphorylates Dlx3 and regulates the function of Dlx3 during osteoblast differentiation.

Li H, Jeong HM, Choi YH, Kim JH, Choi JK, Yeo CY, Jeong HG, Jeong TC, Chun C, Lee KY.

J Cell Biochem. 2014 Nov;115(11):2004-11. doi: 10.1002/jcb.24872.

PMID:
24924519
36.

Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.

Choi JH, Jin SW, Han EH, Park BH, Kim HG, Khanal T, Hwang YP, Do MT, Lee HS, Chung YC, Kim HS, Jeong TC, Jeong HG.

Phytomedicine. 2014 Jul-Aug;21(8-9):1053-61. doi: 10.1016/j.phymed.2014.04.011. Epub 2014 May 20.

PMID:
24854572
37.

A Comparison of the In Vitro Inhibitory Effects of Thelephoric Acid and SKF-525A on Human Cytochrome P450 Activity.

Song M, Do H, Kwon OK, Yang EJ, Bae JS, Jeong TC, Song KS, Lee S.

Biomol Ther (Seoul). 2014 Feb;22(2):155-60. doi: 10.4062/biomolther.2013.107.

38.

Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1.

Kim NH, Lee S, Kang MJ, Jeong HG, Kang W, Jeong TC.

Biomol Ther (Seoul). 2014 Feb;22(2):149-54. doi: 10.4062/biomolther.2014.016.

39.

Absolute bioavailability and metabolism of aceclofenac in rats.

Noh K, Shin BS, Kwon KI, Yun HY, Kim E, Jeong TC, Kang W.

Arch Pharm Res. 2015 Jan;38(1):68-72. doi: 10.1007/s12272-014-0350-4. Epub 2014 Mar 18.

PMID:
24633464
40.

Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway.

Khanal T, Kim HG, Do MT, Choi JH, Won SS, Kang W, Chung YC, Jeong TC, Jeong HG.

Toxicol Appl Pharmacol. 2014 May 15;277(1):39-48. doi: 10.1016/j.taap.2014.03.003. Epub 2014 Mar 12.

PMID:
24631339
41.

Quantitative determination of amisulpride in rat plasma by HPLC-MS/MS.

Noh K, Jang YJ, Kwon KI, Kim E, Jeong TC, Yun HY, Kang W.

Arch Pharm Res. 2015 Jan;38(1):63-7. doi: 10.1007/s12272-014-0361-1. Epub 2014 Mar 12.

PMID:
24619919
42.

Modulation of Atg5 expression by globular adiponectin contributes to autophagy flux and suppression of ethanol-induced cell death in liver cells.

Nepal S, Kim MJ, Lee ES, Kim JA, Choi DY, Sohn DH, Lee SH, Song K, Kim SH, Jeong GS, Jeong TC, Park PH.

Food Chem Toxicol. 2014 Jun;68:11-22. doi: 10.1016/j.fct.2014.02.027. Epub 2014 Feb 27.

PMID:
24582693
43.

Prandial effect on the systemic exposure of amisulpride.

Jang YJ, Jeong TC, Noh K, Baek IW, Kwon KI, Kim E, Yoon YR, Kang W.

Arch Pharm Res. 2014 Oct;37(10):1325-8. doi: 10.1007/s12272-014-0331-7. Epub 2014 Jan 29.

PMID:
24469600
44.

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.

Choi JH, Hwang YP, Kim HG, Khanal T, Do MT, Jin SW, Han HJ, Lee HS, Lee YC, Chung YC, Jeong TC, Jeong HG.

Nutr Cancer. 2014;66(1):140-51. doi: 10.1080/01635581.2014.853087. Epub 2013 Dec 16.

PMID:
24341702
45.

HS-1793, a resveratrol analogue, induces cell cycle arrest and apoptotic cell death in human breast cancer cells.

Kim JA, Kim DH, Hossain MA, Kim MY, Sung B, Yoon JH, Suh H, Jeong TC, Chung HY, Kim ND.

Int J Oncol. 2014 Feb;44(2):473-80. doi: 10.3892/ijo.2013.2207. Epub 2013 Dec 5.

PMID:
24316714
46.

Genipin induces cyclooxygenase-2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in RAW 264.7 cells.

Khanal T, Kim HG, Do MT, Choi JH, Chung YC, Kim HS, Park YJ, Jeong TC, Jeong HG.

Food Chem Toxicol. 2014 Feb;64:126-34. doi: 10.1016/j.fct.2013.11.035. Epub 2013 Dec 1.

PMID:
24296130
47.

The effect of gut microbiota on drug metabolism.

Kang MJ, Kim HG, Kim JS, Oh DG, Um YJ, Seo CS, Han JW, Cho HJ, Kim GH, Jeong TC, Jeong HG.

Expert Opin Drug Metab Toxicol. 2013 Oct;9(10):1295-308. doi: 10.1517/17425255.2013.807798. Epub 2013 Jun 12. Review.

PMID:
24033282
48.

Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages.

Kim MJ, Nepal S, Lee ES, Jeong TC, Kim SH, Park PH.

Toxicol Appl Pharmacol. 2013 Nov 15;273(1):77-89. doi: 10.1016/j.taap.2013.08.005. Epub 2013 Aug 24.

PMID:
23978445
49.

Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells.

Do MT, Kim HG, Choi JH, Khanal T, Park BH, Tran TP, Jeong TC, Jeong HG.

Food Chem. 2013 Dec 1;141(3):2591-9. doi: 10.1016/j.foodchem.2013.04.125. Epub 2013 May 24.

PMID:
23870999
50.

Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.

Song M, Hong M, Lee MY, Jee JG, Lee YM, Bae JS, Jeong TC, Lee S.

Food Chem Toxicol. 2013 Sep;59:549-53. doi: 10.1016/j.fct.2013.06.055. Epub 2013 Jul 5.

PMID:
23835282

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