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Items: 1 to 50 of 213

1.

Mapping Hidden Residual Structure within the Myc bHLH-LZ Domain Using Chemical Denaturant Titration.

Panova S, Cliff MJ, Macek P, Blackledge M, Jensen MR, Nissink JWM, Embrey KJ, Davies R, Waltho JP.

Structure. 2019 Aug 6. pii: S0969-2126(19)30238-2. doi: 10.1016/j.str.2019.07.006. [Epub ahead of print]

PMID:
31402220
2.

Associations of mammographic breast density with breast stem cell marker-defined breast cancer subtypes.

Yaghjyan L, Esnakula AK, Scott CG, Wijayabahu AT, Jensen MR, Vachon CM.

Cancer Causes Control. 2019 Jul 27. doi: 10.1007/s10552-019-01207-w. [Epub ahead of print]

PMID:
31352658
3.

Longitudinal Changes in Volumetric Breast Density in Healthy Women across the Menopausal Transition.

Engmann NJ, Scott C, Jensen MR, Winham SJ, Ma L, Brandt KR, Mahmoudzadeh A, Whaley DH, Hruska CB, Wu FF, Norman AD, Hiatt RA, Heine J, Shepherd J, Pankratz VS, Miglioretti DL, Kerlikowske K, Vachon CM.

Cancer Epidemiol Biomarkers Prev. 2019 Aug;28(8):1324-1330. doi: 10.1158/1055-9965.EPI-18-1375. Epub 2019 Jun 11.

PMID:
31186265
4.

Combined effect of volumetric breast density and body mass index on breast cancer risk.

Engmann NJ, Scott CG, Jensen MR, Winham S, Miglioretti DL, Ma L, Brandt K, Mahmoudzadeh A, Whaley DH, Hruska C, Wu F, Norman AD, Hiatt RA, Heine J, Shepherd J, Pankratz VS, Vachon CM, Kerlikowske K.

Breast Cancer Res Treat. 2019 Aug;177(1):165-173. doi: 10.1007/s10549-019-05283-z. Epub 2019 May 25.

PMID:
31129803
5.

Deciphering mechanisms of response and resistance in large-scale mouse cancer screens.

Prahallad A, Jensen MR, Chapeau EA.

Curr Opin Genet Dev. 2019 Apr 3;54:48-54. doi: 10.1016/j.gde.2019.02.006. [Epub ahead of print] Review.

PMID:
30954760
6.

Body mass index, mammographic density, and breast cancer risk by estrogen receptor subtype.

Shieh Y, Scott CG, Jensen MR, Norman AD, Bertrand KA, Pankratz VS, Brandt KR, Visscher DW, Shepherd JA, Tamimi RM, Vachon CM, Kerlikowske K.

Breast Cancer Res. 2019 Apr 3;21(1):48. doi: 10.1186/s13058-019-1129-9.

7.

EQ-5D Quality-of-Life Analysis and Cost-Effectiveness After Skull Base Meningioma Resection.

Karsy M, Jensen MR, Guan J, Ravindra VM, Bisson EF, Couldwell WT.

Neurosurgery. 2019 Sep 1;85(3):E543-E552. doi: 10.1093/neuros/nyz040.

PMID:
30869135
8.

Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.

Desfosses A, Milles S, Jensen MR, Guseva S, Colletier JP, Maurin D, Schoehn G, Gutsche I, Ruigrok RWH, Blackledge M.

Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201816417. doi: 10.1073/pnas.1816417116. [Epub ahead of print]

PMID:
30787192
9.

Characterization of intrinsically disordered proteins and their dynamic complexes: From in vitro to cell-like environments.

Milles S, Salvi N, Blackledge M, Jensen MR.

Prog Nucl Magn Reson Spectrosc. 2018 Dec;109:79-100. doi: 10.1016/j.pnmrs.2018.07.001. Epub 2018 Jul 31. Review.

PMID:
30527137
10.

Trends and Cost Analysis of Upper Extremity Nerve Injury Using the National (Nationwide) Inpatient Sample.

Karsy M, Watkins R, Jensen MR, Guan J, Brock AA, Mahan MA.

World Neurosurg. 2019 Mar;123:e488-e500. doi: 10.1016/j.wneu.2018.11.192. Epub 2018 Nov 28.

PMID:
30502477
11.

[Chronic rhinosinusitis].

Jensen MR, Arndal E, Buchwald CV.

Ugeskr Laeger. 2018 Nov 19;180(47). pii: V05180344. Danish.

PMID:
30509346
12.

Subtypes in BRCA-mutated breast cancer.

Sønderstrup IMH, Jensen MR, Ejlertsen B, Eriksen JO, Gerdes AM, Kruse TA, Larsen MJ, Thomassen M, Lænkholm AV.

Hum Pathol. 2019 Feb;84:192-201. doi: 10.1016/j.humpath.2018.10.005. Epub 2018 Oct 17. No abstract available.

PMID:
30342055
13.

Elucidating binding mechanisms and dynamics of intrinsically disordered protein complexes using NMR spectroscopy.

Schneider R, Blackledge M, Jensen MR.

Curr Opin Struct Biol. 2019 Feb;54:10-18. doi: 10.1016/j.sbi.2018.09.007. Epub 2018 Oct 11. Review.

PMID:
30316104
14.

An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function.

Milles S, Jensen MR, Lazert C, Guseva S, Ivashchenko S, Communie G, Maurin D, Gerlier D, Ruigrok RWH, Blackledge M.

Sci Adv. 2018 Aug 22;4(8):eaat7778. doi: 10.1126/sciadv.aat7778. eCollection 2018 Aug.

15.

Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.

Jeay S, Ferretti S, Holzer P, Fuchs J, Chapeau EA, Wartmann M, Sterker D, Romanet V, Murakami M, Kerr G, Durand EY, Gaulis S, Cortes-Cros M, Ruetz S, Stachyra TM, Kallen J, Furet P, Würthner J, Guerreiro N, Halilovic E, Jullion A, Kauffmann A, Kuriakose E, Wiesmann M, Jensen MR, Hofmann F, Sellers WR.

Cancer Res. 2018 Nov 1;78(21):6257-6267. doi: 10.1158/0008-5472.CAN-18-0338. Epub 2018 Aug 22.

PMID:
30135191
16.

Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis.

DeMeester KE, Liang H, Jensen MR, Jones ZS, D'Ambrosio EA, Scinto SL, Zhou J, Grimes CL.

J Am Chem Soc. 2018 Aug 1;140(30):9458-9465. doi: 10.1021/jacs.8b03304. Epub 2018 Jul 23.

17.

Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics.

Melková K, Zapletal V, Jansen S, Nomilner E, Zachrdla M, Hritz J, Nováček J, Zweckstetter M, Jensen MR, Blackledge M, Žídek L.

J Biol Chem. 2018 Aug 24;293(34):13297-13309. doi: 10.1074/jbc.RA118.001769. Epub 2018 Jun 20.

PMID:
29925592
18.

Trends and Cost-Analysis of Lower Extremity Nerve Injury Using the National Inpatient Sample.

Foster CH, Karsy M, Jensen MR, Guan J, Eli I, Mahan MA.

Neurosurgery. 2019 Aug 1;85(2):250-256. doi: 10.1093/neuros/nyy265.

PMID:
29889258
19.

Automated and Clinical Breast Imaging Reporting and Data System Density Measures Predict Risk for Screen-Detected and Interval Cancers: A Case-Control Study.

Kerlikowske K, Scott CG, Mahmoudzadeh AP, Ma L, Winham S, Jensen MR, Wu FF, Malkov S, Pankratz VS, Cummings SR, Shepherd JA, Brandt KR, Miglioretti DL, Vachon CM.

Ann Intern Med. 2018 Jun 5;168(11):757-765. doi: 10.7326/M17-3008. Epub 2018 May 1.

20.

Structural basis of the bacteriophage TP901-1 CI repressor dimerization and interaction with DNA.

Rasmussen KK, Varming AK, Schmidt SN, Frandsen KEH, Thulstrup PW, Jensen MR, Lo Leggio L.

FEBS Lett. 2018 May;592(10):1738-1750. doi: 10.1002/1873-3468.13060. Epub 2018 May 13.

21.

Innovative technologies and social inequalities in health: A scoping review of the literature.

Weiss D, Rydland HT, Øversveen E, Jensen MR, Solhaug S, Krokstad S.

PLoS One. 2018 Apr 3;13(4):e0195447. doi: 10.1371/journal.pone.0195447. eCollection 2018. Review.

22.

Characterizing Protein-Protein Interactions Using Solution NMR Spectroscopy.

Ortega-Roldan JL, Blackledge M, Jensen MR.

Methods Mol Biol. 2018;1764:73-85. doi: 10.1007/978-1-4939-7759-8_5.

PMID:
29605909
23.

Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.

Kirkin AF, Dzhandzhugazyan KN, Guldberg P, Fang JJ, Andersen RS, Dahl C, Mortensen J, Lundby T, Wagner A, Law I, Broholm H, Madsen L, Lundell-Ek C, Gjerstorff MF, Ditzel HJ, Jensen MR, Fischer W.

Nat Commun. 2018 Mar 6;9(1):785. doi: 10.1038/s41467-018-03217-9.

24.

Does mammographic density mediate risk factor associations with breast cancer? An analysis by tumor characteristics.

Rice MS, Tamimi RM, Bertrand KA, Scott CG, Jensen MR, Norman AD, Visscher DW, Chen YY, Brandt KR, Couch FJ, Shepherd JA, Fan B, Wu FF, Ma L, Collins LC, Cummings SR, Kerlikowske K, Vachon CM.

Breast Cancer Res Treat. 2018 Jul;170(1):129-141. doi: 10.1007/s10549-018-4735-9. Epub 2018 Mar 3.

25.

The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates.

Jensen MR, Goblirsch BR, Esler MA, Christenson JK, Mohamed FA, Wackett LP, Wilmot CM.

FEBS Lett. 2018 Mar;592(6):987-998. doi: 10.1002/1873-3468.13004. Epub 2018 Feb 19.

26.

Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy.

Delaforge E, Kragelj J, Tengo L, Palencia A, Milles S, Bouvignies G, Salvi N, Blackledge M, Jensen MR.

J Am Chem Soc. 2018 Jan 24;140(3):1148-1158. doi: 10.1021/jacs.7b12407. Epub 2018 Jan 11.

PMID:
29276882
27.

Structural analysis of the complex between influenza B nucleoprotein and human importin-α.

Labaronne A, Milles S, Donchet A, Jensen MR, Blackledge M, Bourhis JM, Ruigrok RWH, Crépin T.

Sci Rep. 2017 Dec 7;7(1):17164. doi: 10.1038/s41598-017-17458-z.

28.

Self-association of a highly charged arginine-rich cell-penetrating peptide.

Tesei G, Vazdar M, Jensen MR, Cragnell C, Mason PE, Heyda J, Skepö M, Jungwirth P, Lund M.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11428-11433. doi: 10.1073/pnas.1712078114. Epub 2017 Oct 11.

29.

OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis.

Jensen MR, Goblirsch BR, Christenson JK, Esler MA, Mohamed FA, Wackett LP, Wilmot CM.

Biochem J. 2017 Nov 10;474(23):3871-3886. doi: 10.1042/BCJ20170642.

30.

Structural and Kinetic Characterization of the Intrinsically Disordered Protein SeV NTAIL through Enhanced Sampling Simulations.

Bernetti M, Masetti M, Pietrucci F, Blackledge M, Jensen MR, Recanatini M, Mollica L, Cavalli A.

J Phys Chem B. 2017 Oct 19;121(41):9572-9582. doi: 10.1021/acs.jpcb.7b08925. Epub 2017 Oct 4.

PMID:
28926706
31.

Thoracolumbar Cortical Screw Placement with Interbody Fusion: Technique and Considerations.

Karsy M, Jensen MR, Cole K, Guan J, Brock A, Cole C.

Cureus. 2017 Jul 2;9(7):e1419. doi: 10.7759/cureus.1419.

32.

Tissue-based associations of mammographic breast density with breast stem cell markers.

Yaghjyan L, Stoll E, Ghosh K, Scott CG, Jensen MR, Brandt KR, Visscher D, Vachon CM.

Breast Cancer Res. 2017 Aug 29;19(1):100. doi: 10.1186/s13058-017-0889-3.

33.

Combining quantitative and qualitative breast density measures to assess breast cancer risk.

Kerlikowske K, Ma L, Scott CG, Mahmoudzadeh AP, Jensen MR, Sprague BL, Henderson LM, Pankratz VS, Cummings SR, Miglioretti DL, Vachon CM, Shepherd JA.

Breast Cancer Res. 2017 Aug 22;19(1):97. doi: 10.1186/s13058-017-0887-5.

34.

The LC8 Recognition Motif Preferentially Samples Polyproline II Structure in Its Free State.

Morgan JL, Jensen MR, Ozenne V, Blackledge M, Barbar E.

Biochemistry. 2017 Sep 5;56(35):4656-4666. doi: 10.1021/acs.biochem.7b00552. Epub 2017 Aug 23.

PMID:
28792212
35.

A vicious circle in chronic lymphoedema pathophysiology? An adipocentric view.

Cucchi F, Rossmeislova L, Simonsen L, Jensen MR, Bülow J.

Obes Rev. 2017 Oct;18(10):1159-1169. doi: 10.1111/obr.12565. Epub 2017 Jun 29. Review.

PMID:
28660651
36.

Interaction of mammographic breast density with menopausal status and postmenopausal hormone use in relation to the risk of aggressive breast cancer subtypes.

Yaghjyan L, Tamimi RM, Bertrand KA, Scott CG, Jensen MR, Pankratz VS, Brandt K, Visscher D, Norman A, Couch F, Shepherd J, Fan B, Chen YY, Ma L, Beck AH, Cummings SR, Kerlikowske K, Vachon CM.

Breast Cancer Res Treat. 2017 Sep;165(2):421-431. doi: 10.1007/s10549-017-4341-2. Epub 2017 Jun 17.

37.

Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.

Desravines DC, Serna Martin I, Schneider R, Mas PJ, Aleksandrova N, Jensen MR, Blackledge M, Hart DJ.

Sci Rep. 2017 Jun 16;7(1):3678. doi: 10.1038/s41598-017-03718-5.

38.

Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).

Sukackaite R, Cornacchia D, Jensen MR, Mas PJ, Blackledge M, Enervald E, Duan G, Auchynnikava T, Köhn M, Hart DJ, Buonomo SBC.

Sci Rep. 2017 May 18;7(1):2119. doi: 10.1038/s41598-017-01910-1.

39.

A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.

Whitley MJ, Xi Z, Bartko JC, Jensen MR, Blackledge M, Gronenborn AM.

Biophys J. 2017 Mar 28;112(6):1135-1146. doi: 10.1016/j.bpj.2017.02.010.

40.

Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.

Chapeau EA, Gembarska A, Durand EY, Mandon E, Estadieu C, Romanet V, Wiesmann M, Tiedt R, Lehar J, de Weck A, Rad R, Barys L, Jeay S, Ferretti S, Kauffmann A, Sutter E, Grevot A, Moulin P, Murakami M, Sellers WR, Hofmann F, Jensen MR.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3151-3156. doi: 10.1073/pnas.1620262114. Epub 2017 Mar 6.

41.

Active Multienzyme Assemblies for Long-Chain Olefinic Hydrocarbon Biosynthesis.

Christenson JK, Jensen MR, Goblirsch BR, Mohamed F, Zhang W, Wilmot CM, Wackett LP.

J Bacteriol. 2017 Apr 11;199(9). pii: e00890-16. doi: 10.1128/JB.00890-16. Print 2017 May 1.

42.

Longitudinal Changes in Volumetric Breast Density with Tamoxifen and Aromatase Inhibitors.

Engmann NJ, Scott CG, Jensen MR, Ma L, Brandt KR, Mahmoudzadeh AP, Malkov S, Whaley DH, Hruska CB, Wu FF, Winham SJ, Miglioretti DL, Norman AD, Heine JJ, Shepherd J, Pankratz VS, Vachon CM, Kerlikowske K.

Cancer Epidemiol Biomarkers Prev. 2017 Jun;26(6):930-937. doi: 10.1158/1055-9965.EPI-16-0882. Epub 2017 Feb 1.

43.

Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort.

Vierkant RA, Degnim AC, Radisky DC, Visscher DW, Heinzen EP, Frank RD, Winham SJ, Frost MH, Scott CG, Jensen MR, Ghosh K, Manduca A, Brandt KR, Whaley DH, Hartmann LC, Vachon CM.

BMC Cancer. 2017 Jan 31;17(1):84. doi: 10.1186/s12885-017-3082-2.

44.

Erratum to: Mammographic texture and risk of breast cancer by tumor type and estrogen receptor status.

Malkov S, Shepherd JA, Scott CG, Tamimi RM, Ma L, Bertrand KA, Couch F, Jensen MR, Mahmoudzadeh AP, Fan B, Norman A, Brandt KR, Pankratz VS, Vachon CM, Kerlikowske K.

Breast Cancer Res. 2017 Jan 4;19(1):1. doi: 10.1186/s13058-016-0797-y. No abstract available.

45.

β-Lactone Synthetase Found in the Olefin Biosynthesis Pathway.

Christenson JK, Richman JE, Jensen MR, Neufeld JY, Wilmot CM, Wackett LP.

Biochemistry. 2017 Jan 17;56(2):348-351. doi: 10.1021/acs.biochem.6b01199. Epub 2017 Jan 3.

46.

Mammographic texture and risk of breast cancer by tumor type and estrogen receptor status.

Malkov S, Shepherd JA, Scott CG, Tamimi RM, Ma L, Bertrand KA, Couch F, Jensen MR, Mahmoudzadeh AP, Fan B, Norman A, Brandt KR, Pankratz VS, Vachon CM, Kerlikowske K.

Breast Cancer Res. 2016 Dec 6;18(1):122. Erratum in: Breast Cancer Res. 2017 Jan 4;19(1):1.

47.

Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097.

Jeay S, Gaulis S, Ferretti S, Bitter H, Ito M, Valat T, Murakami M, Ruetz S, Guthy DA, Rynn C, Jensen MR, Wiesmann M, Kallen J, Furet P, Gessier F, Holzer P, Masuya K, Würthner J, Halilovic E, Hofmann F, Sellers WR, Graus Porta D.

Elife. 2016 Nov 17;5. pii: e19317. doi: 10.7554/eLife.19317. No abstract available.

48.

Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis.

Goblirsch BR, Jensen MR, Mohamed FA, Wackett LP, Wilmot CM.

J Biol Chem. 2016 Dec 23;291(52):26698-26706. doi: 10.1074/jbc.M116.760892. Epub 2016 Nov 4.

49.

Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.

Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M.

Front Mol Biosci. 2016 Sep 13;3:54. doi: 10.3389/fmolb.2016.00054. eCollection 2016. Review.

50.

Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and Experiment.

Mollica L, Bessa LM, Hanoulle X, Jensen MR, Blackledge M, Schneider R.

Front Mol Biosci. 2016 Sep 9;3:52. doi: 10.3389/fmolb.2016.00052. eCollection 2016. Review.

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