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Items: 1 to 50 of 242

1.

Reconfigurable system for automated optimization of diverse chemical reactions.

Bédard AC, Adamo A, Aroh KC, Russell MG, Bedermann AA, Torosian J, Yue B, Jensen KF, Jamison TF.

Science. 2018 Sep 21;361(6408):1220-1225. doi: 10.1126/science.aat0650.

PMID:
30237351
2.

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts.

Stewart MP, Langer R, Jensen KF.

Chem Rev. 2018 Aug 22;118(16):7409-7531. doi: 10.1021/acs.chemrev.7b00678. Epub 2018 Jul 27.

PMID:
30052023
3.

Multistage Microfluidic Platform for the Continuous Synthesis of III-V Core/Shell Quantum Dots.

Baek J, Shen Y, Lignos I, Bawendi MG, Jensen KF.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):10915-10918. doi: 10.1002/anie.201805264. Epub 2018 Jul 18.

PMID:
29944772
4.

Continuous N-Hydroxyphthalimide (NHPI)-Mediated Electrochemical Aerobic Oxidation of Benzylic C-H Bonds.

Mo Y, Jensen KF.

Chemistry. 2018 May 24. doi: 10.1002/chem.201802588. [Epub ahead of print]

PMID:
29797694
5.

Machine Learning in Computer-Aided Synthesis Planning.

Coley CW, Green WH, Jensen KF.

Acc Chem Res. 2018 May 15;51(5):1281-1289. doi: 10.1021/acs.accounts.8b00087. Epub 2018 May 1.

PMID:
29715002
6.

Ligand-Mediated Nanocrystal Growth.

Lazzari S, Theiler PM, Shen Y, Coley CW, Stemmer A, Jensen KF.

Langmuir. 2018 Mar 13;34(10):3307-3315. doi: 10.1021/acs.langmuir.8b00076. Epub 2018 Feb 28.

PMID:
29429346
7.

Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing.

Zhang P, Weeranoppanant N, Thomas DA, Tahara K, Stelzer T, Russell MG, O'Mahony M, Myerson AS, Lin H, Kelly LP, Jensen KF, Jamison TF, Dai C, Cui Y, Briggs N, Beingessner RL, Adamo A.

Chemistry. 2018 Feb 21;24(11):2776-2784. doi: 10.1002/chem.201706004. Epub 2018 Jan 31.

PMID:
29385292
8.

SCScore: Synthetic Complexity Learned from a Reaction Corpus.

Coley CW, Rogers L, Green WH, Jensen KF.

J Chem Inf Model. 2018 Feb 26;58(2):252-261. doi: 10.1021/acs.jcim.7b00622. Epub 2018 Jan 26.

PMID:
29309147
9.

Computer-Assisted Retrosynthesis Based on Molecular Similarity.

Coley CW, Rogers L, Green WH, Jensen KF.

ACS Cent Sci. 2017 Dec 27;3(12):1237-1245. doi: 10.1021/acscentsci.7b00355. Epub 2017 Nov 16.

10.

Continuous purification of active pharmaceutical ingredients utilizing polymer membrane surface wettability.

Imbrogno J, Rogers L, Thomas DA, Jensen KF.

Chem Commun (Camb). 2017 Dec 19;54(1):70-73. doi: 10.1039/c7cc08218e.

PMID:
29210378
11.

Costs of subcutaneous and intravenous administration of trastuzumab for patients with HER2-positive breast cancer.

Olsen J, Jensen KF, Olesen DS, Knoop A.

J Comp Eff Res. 2018 May;7(5):411-419. doi: 10.2217/cer-2017-0048. Epub 2017 Dec 4.

PMID:
29199854
12.

Next-generation in vivo optical imaging with short-wave infrared quantum dots.

Bruns OT, Bischof TS, Harris DK, Franke D, Shi Y, Riedemann L, Bartelt A, Jaworski FB, Carr JA, Rowlands CJ, Wilson MWB, Chen O, Wei H, Hwang GW, Montana DM, Coropceanu I, Achorn OB, Kloepper J, Heeren J, So PTC, Fukumura D, Jensen KF, Jain RK, Bawendi MG.

Nat Biomed Eng. 2017;1. pii: 0056. doi: 10.1038/s41551-017-0056. Epub 2017 Apr 10.

13.

In-Situ Microfluidic Study of Biphasic Nanocrystal Ligand-Exchange Reactions Using an Oscillatory Flow Reactor.

Shen Y, Abolhasani M, Chen Y, Xie L, Yang L, Coley CW, Bawendi MG, Jensen KF.

Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16333-16337. doi: 10.1002/anie.201710899. Epub 2017 Nov 21.

PMID:
29073335
14.

High-throughput Nuclear Delivery and Rapid Expression of DNA via Mechanical and Electrical Cell-Membrane Disruption.

Ding X, Stewart M, Sharei A, Weaver JC, Langer RS, Jensen KF.

Nat Biomed Eng. 2017;1. pii: 0039. doi: 10.1038/s41551-017-0039. Epub 2017 Mar 9.

15.

Automated in Situ Measurement of Gas Solubility in Liquids with a Simple Tube-in-Tube Reactor.

Zhang J, Teixeira AR, Zhang H, Jensen KF.

Anal Chem. 2017 Aug 15;89(16):8524-8530. doi: 10.1021/acs.analchem.7b02264. Epub 2017 Aug 3.

PMID:
28737892
16.

Convolutional Embedding of Attributed Molecular Graphs for Physical Property Prediction.

Coley CW, Barzilay R, Green WH, Jaakkola TS, Jensen KF.

J Chem Inf Model. 2017 Aug 28;57(8):1757-1772. doi: 10.1021/acs.jcim.6b00601. Epub 2017 Jul 25.

PMID:
28696688
17.

Material-Efficient Microfluidic Platform for Exploratory Studies of Visible-Light Photoredox Catalysis.

Coley CW, Abolhasani M, Lin H, Jensen KF.

Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9847-9850. doi: 10.1002/anie.201705148. Epub 2017 Jul 17.

PMID:
28651035
18.

A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets.

Hwang YJ, Coley CW, Abolhasani M, Marzinzik AL, Koch G, Spanka C, Lehmann H, Jensen KF.

Chem Commun (Camb). 2017 Jun 16;53(49):6649-6652. doi: 10.1039/c7cc03584e.

PMID:
28585652
19.

Prediction of Organic Reaction Outcomes Using Machine Learning.

Coley CW, Barzilay R, Jaakkola TS, Green WH, Jensen KF.

ACS Cent Sci. 2017 May 24;3(5):434-443. doi: 10.1021/acscentsci.7b00064. Epub 2017 Apr 18.

20.

A Rapid Total Synthesis of Ciprofloxacin Hydrochloride in Continuous Flow.

Lin H, Dai C, Jamison TF, Jensen KF.

Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8870-8873. doi: 10.1002/anie.201703812. Epub 2017 Jun 20.

PMID:
28561939
21.

Multistage extraction platform for highly efficient and fully continuous purification of nanoparticles.

Shen Y, Weeranoppanant N, Xie L, Chen Y, Lusardi MR, Imbrogno J, Bawendi MG, Jensen KF.

Nanoscale. 2017 Jun 14;9(23):7703-7707. doi: 10.1039/c7nr01826f.

PMID:
28561116
22.

Design and Scaling Up of Microchemical Systems: A Review.

Zhang J, Wang K, Teixeira AR, Jensen KF, Luo G.

Annu Rev Chem Biomol Eng. 2017 Jun 7;8:285-305. doi: 10.1146/annurev-chembioeng-060816-101443. Epub 2017 Apr 3. Review.

PMID:
28375772
23.

A fully automated flow-based approach for accelerated peptide synthesis.

Mijalis AJ, Thomas DA 3rd, Simon MD, Adamo A, Beaumont R, Jensen KF, Pentelute BL.

Nat Chem Biol. 2017 May;13(5):464-466. doi: 10.1038/nchembio.2318. Epub 2017 Feb 28.

PMID:
28244989
24.

Suzuki-Miyaura cross-coupling optimization enabled by automated feedback.

Reizman BJ, Wang YM, Buchwald SL, Jensen KF.

React Chem Eng. 2016 Dec 1;1(6):658-666. Epub 2016 Oct 18.

25.

In vitro and ex vivo strategies for intracellular delivery.

Stewart MP, Sharei A, Ding X, Sahay G, Langer R, Jensen KF.

Nature. 2016 Oct 13;538(7624):183-192. doi: 10.1038/nature19764. Review.

PMID:
27734871
26.

Characterization of Indium Phosphide Quantum Dot Growth Intermediates Using MALDI-TOF Mass Spectrometry.

Xie L, Shen Y, Franke D, Sebastian V, Bawendi MG, Jensen KF.

J Am Chem Soc. 2016 Oct 3. [Epub ahead of print]

PMID:
27690411
27.

A Size-Selective Intracellular Delivery Platform.

Saung MT, Sharei A, Adalsteinsson VA, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Patel N, Mino-Kenudson M, Thayer SP, Langer R, Jensen KF, Liss AS, Love JC.

Small. 2016 Nov;12(42):5873-5881. doi: 10.1002/smll.201601155. Epub 2016 Sep 4.

28.

Feedback in Flow for Accelerated Reaction Development.

Reizman BJ, Jensen KF.

Acc Chem Res. 2016 Sep 20;49(9):1786-96. doi: 10.1021/acs.accounts.6b00261. Epub 2016 Aug 15.

PMID:
27525813
29.

Nanoengineering a library of metallic nanostructures using a single microfluidic reactor.

Sebastián V, Jensen KF.

Nanoscale. 2016 Aug 18;8(33):15288-95. doi: 10.1039/c6nr04104c.

PMID:
27500728
30.

Molecular Engineering of Trifunctional Supported Catalysts for the Aerobic Oxidation of Alcohols.

Fernandes AE, Riant O, Jensen KF, Jonas AM.

Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11044-8. doi: 10.1002/anie.201603673. Epub 2016 Jul 19.

PMID:
27430481
31.

Oscillatory multiphase flow strategy for chemistry and biology.

Abolhasani M, Jensen KF.

Lab Chip. 2016 Jul 19;16(15):2775-84. doi: 10.1039/c6lc00728g. Review.

PMID:
27397146
32.

Portable, Constriction-Expansion Blood Plasma Separation and Polymerization-Based Malaria Detection.

Shatova TA, Lathwal S, Engle MR, Sikes HD, Jensen KF.

Anal Chem. 2016 Aug 2;88(15):7627-32. doi: 10.1021/acs.analchem.6b01355. Epub 2016 Jul 13.

PMID:
27366819
33.

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system.

Adamo A, Beingessner RL, Behnam M, Chen J, Jamison TF, Jensen KF, Monbaliu JC, Myerson AS, Revalor EM, Snead DR, Stelzer T, Weeranoppanant N, Wong SY, Zhang P.

Science. 2016 Apr 1;352(6281):61-7. doi: 10.1126/science.aaf1337.

34.

Shape-controlled continuous synthesis of metal nanostructures.

Sebastian V, Smith CD, Jensen KF.

Nanoscale. 2016 Apr 14;8(14):7534-43. doi: 10.1039/c5nr08531d.

PMID:
26927867
35.

Live-cell protein labelling with nanometre precision by cell squeezing.

Kollmannsperger A, Sharei A, Raulf A, Heilemann M, Langer R, Jensen KF, Wieneke R, Tampé R.

Nat Commun. 2016 Jan 29;7:10372. doi: 10.1038/ncomms10372.

36.

Expanding the test set: Chemicals with potential to disrupt mammalian brain development.

Mundy WR, Padilla S, Breier JM, Crofton KM, Gilbert ME, Herr DW, Jensen KF, Radio NM, Raffaele KC, Schumacher K, Shafer TJ, Cowden J.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt A):25-35. doi: 10.1016/j.ntt.2015.10.001. Epub 2015 Oct 22. Review.

PMID:
26476195
37.

The Unexpected Influence of Precursor Conversion Rate in the Synthesis of III-V Quantum Dots.

Franke D, Harris DK, Xie L, Jensen KF, Bawendi MG.

Angew Chem Int Ed Engl. 2015 Nov 23;54(48):14299-303. doi: 10.1002/anie.201505972. Epub 2015 Oct 6.

PMID:
26437711
38.

Multiphase Oscillatory Flow Strategy for in Situ Measurement and Screening of Partition Coefficients.

Abolhasani M, Coley CW, Jensen KF.

Anal Chem. 2015 Nov 3;87(21):11130-6. doi: 10.1021/acs.analchem.5b03311. Epub 2015 Oct 13.

PMID:
26436292
39.

Simultaneous solvent screening and reaction optimization in microliter slugs.

Reizman BJ, Jensen KF.

Chem Commun (Camb). 2015 Sep 4;51(68):13290-3. doi: 10.1039/c5cc03651h.

PMID:
26201048
40.

Characterization and modeling of multiphase flow in structured microreactors: a post microreactor case study.

Yang L, Shi Y, Abolhasani M, Jensen KF.

Lab Chip. 2015 Aug 7;15(15):3232-41. doi: 10.1039/c5lc00431d.

PMID:
26126496
41.

Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions.

Abolhasani M, Bruno NC, Jensen KF.

Chem Commun (Camb). 2015 May 28;51(43):8916-9. doi: 10.1039/c5cc02051d.

PMID:
25876959
42.

Ex vivo cytosolic delivery of functional macromolecules to immune cells.

Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, von Andrian UH, Anderson DG, Langer R, Lieberman J, Jensen KF.

PLoS One. 2015 Apr 13;10(4):e0118803. doi: 10.1371/journal.pone.0118803. eCollection 2015.

43.

Adenine phosphoribosyltransferase from Sulfolobus solfataricus is an enzyme with unusual kinetic properties and a crystal structure that suggests it evolved from a 6-oxopurine phosphoribosyltransferase.

Jensen KF, Hansen MR, Jensen KS, Christoffersen S, Poulsen JC, Mølgaard A, Kadziola A.

Biochemistry. 2015 Apr 14;54(14):2323-34. doi: 10.1021/bi501334m. Epub 2015 Mar 30.

PMID:
25790177
44.

Achieving Continuous Manufacturing: Technologies and Approaches for Synthesis, Workup, and Isolation of Drug Substance May 20-21, 2014 Continuous Manufacturing Symposium.

Baxendale IR, Braatz RD, Hodnett BK, Jensen KF, Johnson MD, Sharratt P, Sherlock JP, Florence AJ.

J Pharm Sci. 2015 Mar;104(3):781-791. doi: 10.1002/jps.24252. Epub 2016 Jan 8.

PMID:
28756840
45.

Achieving continuous manufacturing: technologies and approaches for synthesis, workup, and isolation of drug substance. May 20-21, 2014 Continuous Manufacturing Symposium.

Baxendale IR, Braatz RD, Hodnett BK, Jensen KF, Johnson MD, Sharratt P, Sherlock JP, Florence AJ.

J Pharm Sci. 2015 Mar;104(3):781-91. doi: 10.1002/jps.24252. Epub 2014 Dec 2. Review.

PMID:
25470351
46.

Microfluidic production of perfluorocarbon-alginate core-shell microparticles for ultrasound therapeutic applications.

Duarte AR, Ünal B, Mano JF, Reis RL, Jensen KF.

Langmuir. 2014 Oct 21;30(41):12391-9. doi: 10.1021/la502822v. Epub 2014 Oct 9.

PMID:
25263163
47.

Engineering the synthesis of silica-gold nano-urchin particles using continuous synthesis.

Sebastian V, Lee SK, Jensen KF.

Nanoscale. 2014 Nov 7;6(21):13228-35. doi: 10.1039/c4nr04021j.

PMID:
25259506
48.

Tools for chemical synthesis in microsystems.

Jensen KF, Reizman BJ, Newman SG.

Lab Chip. 2014 Sep 7;14(17):3206-12. doi: 10.1039/c4lc00330f.

PMID:
24865228
49.

Rapid flow-based peptide synthesis.

Simon MD, Heider PL, Adamo A, Vinogradov AA, Mong SK, Li X, Berger T, Policarpo RL, Zhang C, Zou Y, Liao X, Spokoyny AM, Jensen KF, Pentelute BL.

Chembiochem. 2014 Mar 21;15(5):713-20. doi: 10.1002/cbic.201300796. Epub 2014 Mar 11.

50.

Status of dye solar cell technology as a guideline for further research.

Hinsch A, Veurman W, Brandt H, Jensen KF, Mastroianni S.

Chemphyschem. 2014 Apr 14;15(6):1076-87. doi: 10.1002/cphc.201301083. Epub 2014 Mar 5.

PMID:
24599537

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