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Optimising the sampling procedure for forensic investigation of bruises on pigs.

Barington K, Skovgaard K, Henriksen NL, Jensen HE.

Vet Rec. 2020 Mar 27. pii: vetrec-2019-105625. doi: 10.1136/vr.105625. [Epub ahead of print]


The host response to bacterial bone infection involves a local upregulation of several acute phase proteins.

Lüthje FL, Blirup-Plum SA, Møller NS, Heegaard PMH, Jensen HE, Kirketerp-Møller K, Gottlieb H, Skovgaard K, Jensen LK.

Immunobiology. 2020 Feb 15:151914. doi: 10.1016/j.imbio.2020.151914. [Epub ahead of print]


TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice.

Tougaard P, Martinsen LO, Lützhøft DO, Jensen HE, Flethøj M, Vandenabeele P, Pedersen AE, Skov S, Hansen AK, Hansen CHF.

Int J Obes (Lond). 2020 Jan 30. doi: 10.1038/s41366-020-0539-1. [Epub ahead of print]


The inflammatory response to bone infection - a review based on animal models and human patients.

Lüthje FL, Jensen LK, Jensen HE, Skovgaard K.

APMIS. 2020 Jan 24. doi: 10.1111/apm.13027. [Epub ahead of print] Review.


Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium.

Donnelly JP, Chen SC, Kauffman CA, Steinbach WJ, Baddley JW, Verweij PE, Clancy CJ, Wingard JR, Lockhart SR, Groll AH, Sorrell TC, Bassetti M, Akan H, Alexander BD, Andes D, Azoulay E, Bialek R, Bradsher RW, Bretagne S, Calandra T, Caliendo AM, Castagnola E, Cruciani M, Cuenca-Estrella M, Decker CF, Desai SR, Fisher B, Harrison T, Heussel CP, Jensen HE, Kibbler CC, Kontoyiannis DP, Kullberg BJ, Lagrou K, Lamoth F, Lehrnbecher T, Loeffler J, Lortholary O, Maertens J, Marchetti O, Marr KA, Masur H, Meis JF, Morrisey CO, Nucci M, Ostrosky-Zeichner L, Pagano L, Patterson TF, Perfect JR, Racil Z, Roilides E, Ruhnke M, Prokop CS, Shoham S, Slavin MA, Stevens DA, Thompson GR, Vazquez JA, Viscoli C, Walsh TJ, Warris A, Wheat LJ, White PL, Zaoutis TE, Pappas PG.

Clin Infect Dis. 2019 Dec 5. pii: ciz1008. doi: 10.1093/cid/ciz1008. [Epub ahead of print]


Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.

Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, Hoenigl M, Jensen HE, Lagrou K, Lewis RE, Mellinghoff SC, Mer M, Pana ZD, Seidel D, Sheppard DC, Wahba R, Akova M, Alanio A, Al-Hatmi AMS, Arikan-Akdagli S, Badali H, Ben-Ami R, Bonifaz A, Bretagne S, Castagnola E, Chayakulkeeree M, Colombo AL, Corzo-León DE, Drgona L, Groll AH, Guinea J, Heussel CP, Ibrahim AS, Kanj SS, Klimko N, Lackner M, Lamoth F, Lanternier F, Lass-Floerl C, Lee DG, Lehrnbecher T, Lmimouni BE, Mares M, Maschmeyer G, Meis JF, Meletiadis J, Morrissey CO, Nucci M, Oladele R, Pagano L, Pasqualotto A, Patel A, Racil Z, Richardson M, Roilides E, Ruhnke M, Seyedmousavi S, Sidharthan N, Singh N, Sinko J, Skiada A, Slavin M, Soman R, Spellberg B, Steinbach W, Tan BH, Ullmann AJ, Vehreschild JJ, Vehreschild MJGT, Walsh TJ, White PL, Wiederhold NP, Zaoutis T, Chakrabarti A; Mucormycosis ECMM MSG Global Guideline Writing Group.

Lancet Infect Dis. 2019 Dec;19(12):e405-e421. doi: 10.1016/S1473-3099(19)30312-3. Epub 2019 Nov 5. Review.


Guideline for Preclinical Studies of Bone Infections in Large Animals Based on a Systematic Review of 316 Non-Rodent Models.

Jensen LK, Henriksen NL, Blirup SA, Jensen HE.

J Bone Joint Surg Am. 2019 Nov 6;101(21):1894-1903. doi: 10.2106/JBJS.18.01369.


Comparing the treatment effect of narrow spectrum antimicrobial, probiotic and fluid with amoxicillin in mink kits (Neovison vison) with pre-weaning diarrhea.

Birch JM, Agger JF, Leijon M, Ullman K, Struve T, Jensen HE.

Res Vet Sci. 2019 Aug;125:121-129. doi: 10.1016/j.rvsc.2019.05.021. Epub 2019 Jun 3.


Time-dependent Pathologic and Inflammatory Consequences of Various Blood Sampling Techniques in Mice.

Sørensen DB, Metzdorff SB, Jensen LK, Andersen KH, Teilmann AC, Jensen HE, Frøkiaer H.

J Am Assoc Lab Anim Sci. 2019 May 1;58(3):362-372. doi: 10.30802/AALAS-JAALAS-18-000064. Epub 2019 Apr 4.


Genital Infiltrations of CD4+ and CD8+ T Lymphocytes, IgA+ and IgG+ Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Chlamydia trachomatis Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With CAF01.

Erneholm K, Lorenzen E, Bøje S, Olsen AW, Jungersen G, Jensen HE, Cassidy JP, Andersen P, Agerholm JS, Follmann F.

Front Microbiol. 2019 Feb 8;10:197. doi: 10.3389/fmicb.2019.00197. eCollection 2019.


Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology.

Astrup LB, Skovgaard K, Rasmussen RS, Iburg TM, Agerholm JS, Aalbæk B, Jensen HE, Nielsen OL, Johansen FF, Heegaard PMH, Leifsson PS.

Neurol Res. 2019 May;41(5):399-412. doi: 10.1080/01616412.2019.1573455. Epub 2019 Feb 1.


Transfer of amoxicillin to suckling mink (Neovison vison) kits via the milk from dams treated orally or intra-muscularly.

Birch JM, Frandsen HL, Struve T, Agger JF, Jensen HE.

Res Vet Sci. 2019 Apr;123:47-50. doi: 10.1016/j.rvsc.2018.12.008. Epub 2018 Dec 19.


In Vivo Gentamicin Susceptibility Test for Prevention of Bacterial Biofilms in Bone Tissue and on Implants.

Jensen LK, Bjarnsholt T, Kragh KN, Aalbæk B, Henriksen NL, Blirup SA, Pankoke K, Petersen A, Jensen HE.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01889-18. doi: 10.1128/AAC.01889-18. Print 2019 Feb.


Dam characteristics associated with pre-weaning diarrhea in mink (Neovison vison).

Birch JM, Agger JF, Aalbæk B, Struve T, Hammer AS, Jensen HE.

Acta Vet Scand. 2018 Nov 12;60(1):73. doi: 10.1186/s13028-018-0427-z.


Inhibitors of the renin-angiotensin system ameliorates clinical and pathological aspects of experimentally induced nephrotoxic serum nephritis.

Ougaard ME, Jensen HE, Thuen ID, Petersen EG, Kvist PH.

Ren Fail. 2018 Nov;40(1):640-648. doi: 10.1080/0886022X.2018.1533867.


Investigation of the viral and bacterial microbiota in intestinal samples from mink (Neovison vison) with pre-weaning diarrhea syndrome using next generation sequencing.

Birch JM, Ullman K, Struve T, Agger JF, Hammer AS, Leijon M, Jensen HE.

PLoS One. 2018 Oct 18;13(10):e0205890. doi: 10.1371/journal.pone.0205890. eCollection 2018.


Histological evaluation of experimental porcine bruises.

Barington K, Skovgaard K, Henriksen NL, Johansen ASB, Jensen HE.

Data Brief. 2018 Sep 1;20:1166-1176. doi: 10.1016/j.dib.2018.08.134. eCollection 2018 Oct.


Forensic age determination of human inflicted porcine bruises inflicted within 10 h prior to slaughter by application of gene expression signatures.

Barington K, Jensen HE, Skovgaard K.

Res Vet Sci. 2018 Oct;120:47-53. doi: 10.1016/j.rvsc.2018.08.007. Epub 2018 Sep 3.


Temporal Regulation of Glomerular and Cortical Tubulointerstitial Genes Involved in the Development of Nephrotoxic Serum Nephritis.

Ougaard ME, Sembach FE, Kvist PH, Tonnesen M, Frederiksen KS, Egfjord M, Jensen HE, Galsgaard ED.

Nephron. 2018;140(3):218-230. doi: 10.1159/000492294. Epub 2018 Sep 11.


Mink (Neovison vison) kits with pre-weaning diarrhea have elevated serum amyloid A levels and intestinal pathomorphological similarities with New Neonatal Porcine Diarrhea Syndrome.

Mathiesen R, Birch JM, Chriél M, Jensen HE, Agger JF, Heegaard PMH, Struve T.

Acta Vet Scand. 2018 Aug 15;60(1):48. doi: 10.1186/s13028-018-0403-7.


Guidelines for porcine models of human bacterial infections.

Jensen LK, Henriksen NL, Jensen HE.

Lab Anim. 2019 Apr;53(2):125-136. doi: 10.1177/0023677218789444. Epub 2018 Aug 8. Review.


Isavuconazole in a Successful Combination Treatment of Disseminated Mucormycosis in a Child with Acute Lymphoblastic Leukaemia and Generalized Haemochromatosis: A Case Report and Review of the Literature.

Pomorska A, Malecka A, Jaworski R, Radon-Proskura J, Hare RK, Nielsen HV, Andersen LO, Jensen HE, Arendrup MC, Irga-Jaworska N.

Mycopathologia. 2019 Feb;184(1):81-88. doi: 10.1007/s11046-018-0287-0. Epub 2018 Jul 23. Review.


The intensity of the inflammatory response in experimental porcine bruises depends on time, anatomical location and sampling site.

Barington K, Skovgaard K, Henriksen NL, Johansen ASB, Jensen HE.

J Forensic Leg Med. 2018 Aug;58:130-139. doi: 10.1016/j.jflm.2018.06.005. Epub 2018 Jun 23.


A porcine model for pathomorphological age assessment of surgically excised skin wounds.

Barington K, Dich-Jørgensen K, Jensen HE.

Acta Vet Scand. 2018 May 30;60(1):33. doi: 10.1186/s13028-018-0387-3.


Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease.

Ougaard MKE, Kvist PH, Jensen HE, Hess C, Rune I, Søndergaard H.

Int J Nephrol. 2018 Mar 5;2018:8424502. doi: 10.1155/2018/8424502. eCollection 2018.


Corrigendum: Fungal infections in animals: a patchwork of different situations.

Seyedmousavi S, Bosco SMG, de Hoog S, Ebel F, Elad D, Gomes RR, Jacobsen ID, Jensen HE, Martel A, Mignon B, Pasmans F, Piecková E, Rodrigues AM, Singh K, Vicente VA, Wibbelt G, Wiederhold NP, Guillot J.

Med Mycol. 2018 Nov 1;56(8):e4. doi: 10.1093/mmy/myy028. No abstract available.


Pigs are useful for the molecular study of bone inflammation and regeneration in humans.

Lüthje FL, Skovgaard K, Jensen HE, Kruse Jensen L.

Lab Anim. 2018 Dec;52(6):630-640. doi: 10.1177/0023677218766391. Epub 2018 Apr 13.


Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology.

Jensen LK, Henriksen NL, Bjarnsholt T, Kragh KN, Jensen HE.

J Bone Jt Infect. 2018 Feb 20;3(1):27-36. doi: 10.7150/jbji.22799. eCollection 2018.


Fungal infections in animals: a patchwork of different situations.

Seyedmousavi S, Bosco SMG, de Hoog S, Ebel F, Elad D, Gomes RR, Jacobsen ID, Jensen HE, Martel A, Mignon B, Pasmans F, Piecková E, Rodrigues AM, Singh K, Vicente VA, Wibbelt G, Wiederhold NP, Guillot J.

Med Mycol. 2018 Apr 1;56(suppl_1):165-187. doi: 10.1093/mmy/myx104. Review. Erratum in: Med Mycol. 2018 Nov 1;56(8):e4.


Suppurative Inflammation and Local Tissue Destruction Reduce the Penetration of Cefuroxime to Infected Bone Implant Cavities.

Jensen LK, Koch J, Henriksen NL, Bue M, Tøttrup M, Hanberg P, Søballe K, Jensen HE.

J Comp Pathol. 2017 Nov;157(4):308-316. doi: 10.1016/j.jcpa.2017.10.001. Epub 2017 Nov 8.


Porcine Models of Biofilm Infections with Focus on Pathomorphology.

Jensen LK, Johansen ASB, Jensen HE.

Front Microbiol. 2017 Oct 10;8:1961. doi: 10.3389/fmicb.2017.01961. eCollection 2017. Review.


Single-dose bone pharmacokinetics of vancomycin in a porcine implant-associated osteomyelitis model.

Bue M, Hanberg P, Koch J, Jensen LK, Lundorff M, Aalbaek B, Jensen HE, Søballe K, Tøttrup M.

J Orthop Res. 2018 Apr;36(4):1093-1098. doi: 10.1002/jor.23776. Epub 2017 Nov 22.


Risk factors associated with diarrhea in Danish commercial mink (Neovison vison) during the pre-weaning period.

Birch JM, Agger JF, Dahlin C, Jensen VF, Hammer AS, Struve T, Jensen HE.

Acta Vet Scand. 2017 Jun 29;59(1):43. doi: 10.1186/s13028-017-0312-1.


The effect of color type on early wound healing in farmed mink (Neovison vison).

Jespersen A, Jensen HE, Agger JF, Heegaard PMH, Damborg P, Aalbæk B, Hammer AS.

BMC Vet Res. 2017 May 22;13(1):135. doi: 10.1186/s12917-017-1052-1.


Forensic aspects of gene expression signatures for age determination in bruises as evaluated in an experimental porcine model.

Barington K, Jensen HE, Skovgaard K.

Forensic Sci Med Pathol. 2017 Jun;13(2):151-160. doi: 10.1007/s12024-017-9869-2. Epub 2017 May 2.


Scrotal granulomatous aspergillosis in a dromedary camel (Camelus dromedarius).

Scaglione FE, Peano A, Piga S, Meda S, Bollo E, Cannizzo FT, Pasquetti M, Jensen HE.

BMC Vet Res. 2017 Mar 29;13(1):79. doi: 10.1186/s12917-017-1001-z.


Forensic aspects of incised wounds and bruises in pigs established post-mortem.

Barington K, Jensen HE.

Res Vet Sci. 2017 Jun;112:42-45. doi: 10.1016/j.rvsc.2017.01.013. Epub 2017 Jan 15.


Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response.

Jensen LK, Koch J, Dich-Jorgensen K, Aalbaek B, Petersen A, Fuursted K, Bjarnsholt T, Kragh KN, Tøtterup M, Bue M, Hanberg P, Søballe K, Heegaard PMH, Jensen HE.

J Orthop Res. 2017 Oct;35(10):2211-2221. doi: 10.1002/jor.23505. Epub 2017 Jan 15.


Gross and histopathological evaluation of human inflicted bruises in Danish slaughter pigs.

Barington K, Agger JF, Nielsen SS, Dich-Jørgensen K, Jensen HE.

BMC Vet Res. 2016 Nov 8;12(1):247.


Characterization of hemorrhages in the ham topsides and tenderloins of slaughter pigs.

Dich-Jørgensen K, Larsen HD, Leifsson PS, Jensen HE.

Meat Sci. 2017 Feb;124:34-38. doi: 10.1016/j.meatsci.2016.10.016. Epub 2016 Oct 29.


Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir.

Jensen LK, Koch J, Aalbaek B, Moodley A, Bjarnsholt T, Kragh KN, Petersen A, Jensen HE.

APMIS. 2017 Jan;125(1):38-45. doi: 10.1111/apm.12597. Epub 2016 Oct 5.


Genital tract lesions in sexually mature Göttingen minipigs during the initial stages of experimental vaginal infection with Chlamydia trachomatis serovar D.

Erneholm K, Lorenzen E, Bøje S, Olsen AW, Andersen P, Cassidy JP, Follmann F, Jensen HE, Agerholm JS.

BMC Vet Res. 2016 Sep 10;12(1):200. doi: 10.1186/s12917-016-0793-6.


A retrospective study of forensic cases of skin ulcerations in Danish pigs from 2000 to 2014.

Barington K, Dich-Jørgensen K, Jensen HE.

Acta Vet Scand. 2016 Jul 15;58(1):48. doi: 10.1186/s13028-016-0229-0.


Characterization of hemorrhages in the tenderloins of slaughter pigs.

Dich-Jørgensen K, McEvoy FJ, Larsen HD, Leifsson PS, Jensen HE.

Meat Sci. 2016 Nov;121:250-252. doi: 10.1016/j.meatsci.2016.06.026. Epub 2016 Jun 24.


Distinct galactofuranose antigens in the cell wall and culture supernatants as a means to differentiate Fusarium from Aspergillus species.

Wiedemann A, Kakoschke TK, Speth C, Rambach G, Ensinger C, Jensen HE, Ebel F.

Int J Med Microbiol. 2016 Sep;306(6):381-90. doi: 10.1016/j.ijmm.2016.05.002. Epub 2016 May 10.


The impact of force on the timing of bruises evaluated in a porcine model.

Barington K, Jensen HE.

J Forensic Leg Med. 2016 May;40:61-6. doi: 10.1016/j.jflm.2016.03.005. Epub 2016 Apr 2.



Andersen KG, Duriaud HM, Jensen HE, Kroman N, Kehlet H.

Pain. 2016 May;157(5):1174. doi: 10.1097/j.pain.0000000000000500. No abstract available.


The origin of Pasteurella multocida impacts pathology and inflammation when assessed in a mouse model.

Pors SE, Chadfield MS, Sørensen DB, Offenberg H, Bisgaard M, Jensen HE.

Res Vet Sci. 2016 Apr;105:139-42. doi: 10.1016/j.rvsc.2016.02.007. Epub 2016 Feb 6.


Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model.

Tøttrup M, Bue M, Koch J, Jensen LK, Hanberg P, Aalbæk B, Fuursted K, Jensen HE, Søballe K.

J Bone Joint Surg Am. 2016 Mar 2;98(5):363-9. doi: 10.2106/JBJS.O.00550.


Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

Olsen HG, Kjelgaard-Hansen M, Tveden-Nyborg P, Birck MM, Hammelev KP, Vegge A, Aalbæk B, Leifsson PS, Jensen HE, Iburg T, Heegaard PM, Nielsen OL.

BMC Res Notes. 2016 Feb 16;9:99. doi: 10.1186/s13104-016-1888-7.

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