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Items: 1 to 50 of 220

1.

HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.

Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG Jr.

Sci Signal. 2019 Oct 1;12(601). pii: eaay0482. doi: 10.1126/scisignal.aay0482.

PMID:
31575731
2.

PD-L1 Expression and Clinical Outcomes to Cabozantinib, Everolimus, and Sunitinib in Patients with Metastatic Renal Cell Carcinoma: Analysis of the Randomized Clinical Trials METEOR and CABOSUN.

Flaifel A, Xie W, Braun DA, Ficial M, Bakouny Z, Nassar AH, Jennings RB, Escudier B, George DJ, Motzer RJ, Morris MJ, Powles T, Wang E, Huang Y, Freeman GJ, Choueiri TK, Signoretti S.

Clin Cancer Res. 2019 Oct 15;25(20):6080-6088. doi: 10.1158/1078-0432.CCR-19-1135. Epub 2019 Aug 1.

PMID:
31371341
3.

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.

Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr.

Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14.

PMID:
30872525
4.

Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival.

Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG Jr.

Cancer Discov. 2019 Feb;9(2):230-247. doi: 10.1158/2159-8290.CD-18-0389. Epub 2018 Oct 29.

5.

Ischemic QRS prolongation as a predictor of ventricular fibrillation in a canine model.

Almer J, Jennings RB, Ringborn M, Engblom H.

Scand Cardiovasc J. 2018 Oct;52(5):262-267. doi: 10.1080/14017431.2018.1494304. Epub 2018 Sep 5.

6.

Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.

McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG Jr.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3741-E3748. doi: 10.1073/pnas.1716029115. Epub 2018 Apr 2.

7.

Enough is not enough: Medical students' knowledge of early warning signs of childhood cancer.

Geel JA, Stevenson BT, Jennings RB, Krook LE, Winnan SJ, Katz BT, Fox TJ, Nyati L.

S Afr Med J. 2017 Jun 30;107(7):585-589. doi: 10.7196/SAMJ.2017.v107i7.12211.

PMID:
29025447
8.

The sensitive period for auditory-vocal learning in the zebra finch: Consequences of limited-model availability and multiple-tutor paradigms on song imitation.

Gobes SMH, Jennings RB, Maeda RK.

Behav Processes. 2019 Jun;163:5-12. doi: 10.1016/j.beproc.2017.07.007. Epub 2017 Jul 23. Review.

PMID:
28743517
9.

Ischemic QRS prolongation as a biomarker of severe myocardial ischemia.

Almer J, Jennings RB, Maan AC, Ringborn M, Maynard C, Pahlm O, Arheden H, Wagner GS, Engblom H.

J Electrocardiol. 2016 Mar-Apr;49(2):139-47. doi: 10.1016/j.jelectrocard.2015.12.010. Epub 2015 Dec 23.

PMID:
26810927
10.

Relationship of T2-Weighted MRI Myocardial Hyperintensity and the Ischemic Area-At-Risk.

Kim HW, Van Assche L, Jennings RB, Wince WB, Jensen CJ, Rehwald WG, Wendell DC, Bhatti L, Spatz DM, Parker MA, Jenista ER, Klem I, Crowley AL, Chen EL, Judd RM, Kim RJ.

Circ Res. 2015 Jul 17;117(3):254-65. doi: 10.1161/CIRCRESAHA.117.305771. Epub 2015 May 13.

11.

Roles of collateral arterial flow and ischemic preconditioning in protection of acutely ischemic myocardium.

Jennings RB, Wagner GS.

J Electrocardiol. 2014 Jul-Aug;47(4):491-9. doi: 10.1016/j.jelectrocard.2014.04.015. Epub 2014 Apr 30. Review.

PMID:
24952922
12.

An electrocardiographic sign of ischemic preconditioning.

Meijs LP, Galeotti L, Pueyo EP, Romero D, Jennings RB, Ringborn M, Warren SG, Wagner GS, Strauss DG.

Am J Physiol Heart Circ Physiol. 2014 Jul 1;307(1):H80-7. doi: 10.1152/ajpheart.00419.2013. Epub 2014 Apr 28.

13.

Historical perspective on the pathology of myocardial ischemia/reperfusion injury.

Jennings RB.

Circ Res. 2013 Aug 2;113(4):428-38. doi: 10.1161/CIRCRESAHA.113.300987. Review.

PMID:
23908330
14.

Immediate pain response to interlaminar lumbar epidural steroid administration: response characteristics and effects of anesthetic concentration.

Bartynski WS, Jennings RB, Rothfus WE, Agarwal V.

AJNR Am J Neuroradiol. 2013 Jan;34(1):239-46. doi: 10.3174/ajnr.A3170. Epub 2012 Jul 5.

15.

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop.

Schwartz Longacre L, Kloner RA, Arai AE, Baines CP, Bolli R, Braunwald E, Downey J, Gibbons RJ, Gottlieb RA, Heusch G, Jennings RB, Lefer DJ, Mentzer RM, Murphy E, Ovize M, Ping P, Przyklenk K, Sack MN, Vander Heide RS, Vinten-Johansen J, Yellon DM; National Heart, Lung, and Blood Institute, National Institutes of Health.

Circulation. 2011 Sep 6;124(10):1172-9. doi: 10.1161/CIRCULATIONAHA.111.032698. No abstract available.

16.

Commentary on selected aspects of cardioprotection.

Jennings RB.

J Cardiovasc Pharmacol Ther. 2011 Sep-Dec;16(3-4):340-8. doi: 10.1177/1074248411408314. Review.

PMID:
21821537
17.

Effects of ischemic preconditioning and arterial collateral flow on ST-segment elevation and QRS complex prolongation in a canine model of acute coronary occlusion.

Floyd JS, Maynard C, Weston P, Johanson P, Jennings RB, Wagner GS.

J Electrocardiol. 2009 Jan-Feb;42(1):19-26. doi: 10.1016/j.jelectrocard.2008.09.006.

PMID:
19070706
18.

Pharmacological preconditioning with diazoxide slows energy metabolism during sustained ischemia.

Schwartz LM, Reimer KA, Crago MS, Jennings RB.

Exp Clin Cardiol. 2007 Fall;12(3):139-47.

19.

Lower cervical nerve root block using CT fluoroscopy in patients with large body habitus: another benefit of the swimmer's position.

Bartynski WS, Whitt DS, Sheetz MA, Jennings RB, Rothfus WE.

AJNR Am J Neuroradiol. 2007 Apr;28(4):706-8.

20.

The value of both ST-segment and QRS complex changes during acute coronary occlusion for prediction of reperfusion-induced myocardial salvage in a canine model.

Weston P, Johanson P, Schwartz LM, Maynard C, Jennings RB, Wagner GS.

J Electrocardiol. 2007 Jan;40(1):18-25. Epub 2006 Oct 25.

PMID:
17069840
21.

The impact of a journal and its editor on a career in experimental cardiology.

Jennings RB.

Circ Res. 2003 May 30;92(10):1057-8. No abstract available.

PMID:
12775652
22.

Protection of ischemic myocardium in dogs using intracoronary 2,3-butanedione monoxime (BDM).

Sebbag L, Verbinski SG, Reimer KA, Jennings RB.

J Mol Cell Cardiol. 2003 Feb;35(2):165-76.

PMID:
12606257
23.

PCr overshoot': a study of the duration in canine myocardium.

Straeter-Knowlen IM, Butterworth EJ, Buchthal SD, Hollander JA, Caulfield JB, Jennings RB, Evanochko WT.

NMR Biomed. 2002 Feb;15(1):52-9.

PMID:
11840553
24.

Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 2.

Kloner RA, Jennings RB.

Circulation. 2001 Dec 18;104(25):3158-67. Review.

PMID:
11748117
25.

Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 1.

Kloner RA, Jennings RB.

Circulation. 2001 Dec 11;104(24):2981-9. Review.

PMID:
11739316
26.

Metabolism of preconditioned myocardium: effect of loss and reinstatement of cardioprotection.

Jennings RB, Sebbag L, Schwartz LM, Crago MS, Reimer KA.

J Mol Cell Cardiol. 2001 Sep;33(9):1571-88.

PMID:
11549338
27.

Duration and reinstatement of myocardial protection against infarction by ischemic preconditioning in open chest dogs.

Schwartz LM, Sebbag L, Jennings RB, Reimer KA.

J Mol Cell Cardiol. 2001 Sep;33(9):1561-70.

PMID:
11549337
28.

Premedication with the opioid analgesic butorphanol raises the threshold for ischemic preconditioning in dogs.

Schwartz LM, Jennings RB, Reimer KA.

Basic Res Cardiol. 1997 Apr;92(2):106-14.

PMID:
9166990
29.
30.
31.

Reducing lactate accumulation does not attenuate lethal ischemic injury in isolated perfused rat hearts.

Vander Heide RS, Delyani JA, Jennings RB, Reimer KA, Steenbergen C.

Am J Physiol. 1996 Jan;270(1 Pt 2):H38-44.

PMID:
8769732
32.

Effect of reversible ischemia on the activity of the mitochondrial ATPase: relationship to ischemic preconditioning.

Vander Heide RS, Hill ML, Reimer KA, Jennings RB.

J Mol Cell Cardiol. 1996 Jan;28(1):103-12.

PMID:
8745218
33.

Ischemic preconditioning: a brief review.

Reimer KA, Jennings RB.

Basic Res Cardiol. 1996 Jan-Feb;91(1):1-4. Review. No abstract available.

PMID:
8660246
34.

Effect of catecholamine depletion on myocardial infarct size in dogs: role of catecholamines in ischemic preconditioning.

Vander Heide RS, Schwartz LM, Jennings RB, Reimer KA.

Cardiovasc Res. 1995 Nov;30(5):656-62.

PMID:
8595609
35.

Myocardial beta-adrenergic receptor function and high-energy phosphates in brain death--related cardiac dysfunction.

Bittner HB, Chen EP, Milano CA, Kendall SW, Jennings RB, Sabiston DC Jr, Van Trigt P.

Circulation. 1995 Nov 1;92(9 Suppl):II472-8.

PMID:
7586457
36.

Myocardial ischemia and reperfusion.

Jennings RB, Steenbergen C Jr, Reimer KA.

Monogr Pathol. 1995;37:47-80. Review.

PMID:
7603485
37.

Ischemic preconditioning slows ischemic metabolism and limits myocardial infarct size.

Reimer KA, Vander Heide RS, Jennings RB.

Ann N Y Acad Sci. 1994 Jun 17;723:99-115. Review. No abstract available.

PMID:
8030928
38.

Acute myocardial ischemia: effects of reperfusion with arterial blood.

Jennings RB, Reimer KA.

Artif Cells Blood Substit Immobil Biotechnol. 1994;22(2):253-78.

PMID:
8087247
39.

Superoxide dismutase plus catalase therapy delays neither cell death nor the loss of the TTC reaction in experimental myocardial infarction in dogs.

Tanaka M, Richard VJ, Murry CE, Jennings RB, Reimer KA.

J Mol Cell Cardiol. 1993 Apr;25(4):367-78.

PMID:
8340930
40.

Adenosine slows ischaemic metabolism in canine myocardium in vitro: relationship to ischaemic preconditioning.

Vander Heide RS, Reimer KA, Jennings RB.

Cardiovasc Res. 1993 Apr;27(4):669-73.

PMID:
8324803
41.

Cardiac protection by ischaemic preconditioning is not mediated by myocardial stunning.

Matsuda M, Catena TG, Vander Heide RS, Jennings RB, Reimer KA.

Cardiovasc Res. 1993 Apr;27(4):585-92.

PMID:
8324790
42.

Effect of anti-CD18 antibody on myocardial neutrophil accumulation and infarct size after ischemia and reperfusion in dogs.

Tanaka M, Brooks SE, Richard VJ, FitzHarris GP, Stoler RC, Jennings RB, Arfors KE, Reimer KA.

Circulation. 1993 Feb;87(2):526-35.

PMID:
8093866
43.

Pediatric preventive cardiology: experience in the Tidewater, Virginia area.

Jennings RB, Leon SP.

Clin Pediatr (Phila). 1992 Feb;31(2):89-93.

PMID:
1544281
44.

Effect of inhibition of the mitochondrial ATPase on net myocardial ATP in total ischemia.

Jennings RB, Reimer KA, Steenbergen C.

J Mol Cell Cardiol. 1991 Dec;23(12):1383-95.

PMID:
1839801
45.

Energy metabolism in preconditioned and control myocardium: effect of total ischemia.

Jennings RB, Murry CE, Reimer KA.

J Mol Cell Cardiol. 1991 Dec;23(12):1449-58.

PMID:
1811060
46.

Preconditioning myocardium with ischemia.

Jennings RB, Murry CE, Reimer KA.

Cardiovasc Drugs Ther. 1991 Oct;5(5):933-8. Review.

PMID:
1756140
47.

New insights into potential mechanisms of ischemic preconditioning.

Murry CE, Jennings RB, Reimer KA.

Circulation. 1991 Jul;84(1):442-5. No abstract available.

PMID:
2060119
48.

Myocardial protection is lost before contractile function recovers from ischemic preconditioning.

Murry CE, Richard VJ, Jennings RB, Reimer KA.

Am J Physiol. 1991 Mar;260(3 Pt 2):H796-804.

PMID:
2000974
49.

Hypoxic reperfusion to remove ischaemic catabolites prior to arterial reperfusion does not limit the size of myocardial infarcts in dogs.

Tanaka M, Earnhardt RC, Murry CE, Richard VJ, Jennings RB, Reimer KA.

Cardiovasc Res. 1991 Jan;25(1):7-16.

PMID:
2054833
50.

The cell biology of acute myocardial ischemia.

Jennings RB, Reimer KA.

Annu Rev Med. 1991;42:225-46. Review.

PMID:
2035969

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