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Items: 1 to 50 of 110

1.

Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA.

Lao Z, Kelly CJ, Yang XY, Jenkins WT, Toorens E, Ganguly T, Evans SM, Koch CJ.

PLoS One. 2015 Jul 24;10(7):e0133895. doi: 10.1371/journal.pone.0133895. eCollection 2015.

2.

Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients.

Koch CJ, Lustig RA, Yang XY, Jenkins WT, Wolf RL, Martinez-Lage M, Desai A, Williams D, Evans SM.

Transl Oncol. 2014 Dec;7(6):752-8. doi: 10.1016/j.tranon.2014.10.004.

3.

Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells.

Sood N, Jenkins WT, Yang XY, Shah NN, Katz JS, Koch CJ, Frail PR, Therien MJ, Hammer DA, Evans SM.

J Pharm (Cairo). 2013;2013. pii: 932797.

4.

Mechanisms of blood flow and hypoxia production in rat 9L-epigastric tumors.

Koch CJ, Jenkins WT, Jenkins KW, Yang XY, Shuman AL, Pickup S, Riehl CR, Paudyal R, Poptani H, Evans SM.

Tumor Microenviron Ther. 2013 Jan;1:1-13.

5.

In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.

Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C.

Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25.

6.

Early detection of radiation therapy response in non-Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging.

Lee SC, Poptani H, Pickup S, Jenkins WT, Kim S, Koch CJ, Delikatny EJ, Glickson JD.

NMR Biomed. 2010 Jul;23(6):624-32. doi: 10.1002/nbm.1505.

PMID:
20661875
7.

The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study.

Evans SM, Jenkins KW, Chen HI, Jenkins WT, Judy KD, Hwang WT, Lustig RA, Judkins AR, Grady MS, Hahn SM, Koch CJ.

Transl Oncol. 2010 Jun 1;3(3):160-9.

8.

The radiation response of cells from 9L gliosarcoma tumours is correlated with [F18]-EF5 uptake.

Koch CJ, Shuman AL, Jenkins WT, Kachur AV, Karp JS, Freifelder R, Dolbier WR Jr, Evans SM.

Int J Radiat Biol. 2009 Dec;85(12):1137-47. doi: 10.3109/09553000903242172.

9.

Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors.

Evans SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ.

Radiat Res. 2008 Dec;170(6):677-90. doi: 10.1667/RR1207.1.

10.

EF5 binding and clinical outcome in human soft tissue sarcomas.

Evans SM, Fraker D, Hahn SM, Gleason K, Jenkins WT, Jenkins K, Hwang WT, Zhang P, Mick R, Koch CJ.

Int J Radiat Oncol Biol Phys. 2006 Mar 1;64(3):922-7.

PMID:
16458778
11.

Hypoxia is important in the biology and aggression of human glial brain tumors.

Evans SM, Judy KD, Dunphy I, Jenkins WT, Hwang WT, Nelson PT, Lustig RA, Jenkins K, Magarelli DP, Hahn SM, Collins RA, Grady MS, Koch CJ.

Clin Cancer Res. 2004 Dec 15;10(24):8177-84.

12.

Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding.

Evans SM, Judy KD, Dunphy I, Jenkins WT, Nelson PT, Collins R, Wileyto EP, Jenkins K, Hahn SM, Stevens CW, Judkins AR, Phillips P, Geoerger B, Koch CJ.

Cancer Res. 2004 Mar 1;64(5):1886-92.

13.

Cyclophosphamide treatment modifies tumor oxygenation and glycolytic rates of RIF-1 tumors: 13C magnetic resonance spectroscopy, Eppendorf electrode, and redox scanning.

Poptani H, Bansal N, Jenkins WT, Blessington D, Mancuso A, Nelson DS, Feldman M, Delikatny EJ, Chance B, Glickson JD.

Cancer Res. 2003 Dec 15;63(24):8813-20.

14.

Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5.

Ziemer LS, Evans SM, Kachur AV, Shuman AL, Cardi CA, Jenkins WT, Karp JS, Alavi A, Dolbier WR Jr, Koch CJ.

Eur J Nucl Med Mol Imaging. 2003 Feb;30(2):259-66. Epub 2002 Nov 23.

PMID:
12552344
15.

Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion.

Koch CJ, Oprysko PR, Shuman AL, Jenkins WT, Brandt G, Evans SM.

Cancer Res. 2002 Jul 1;62(13):3626-9.

16.

Effects of hyperglycemia on oxygenation, radiosensitivity and bioenergetic status of subcutaneous RIF-1 tumors.

Nadal-Desbarats L, Poptani H, Oprysko P, Jenkins WT, Busch TM, Nelson DS, Glickson JD, Koch CJ, Evans SM.

Int J Oncol. 2002 Jul;21(1):103-10.

PMID:
12063556
17.

Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations.

Gee MS, Saunders HM, Lee JC, Sanzo JF, Jenkins WT, Evans SM, Trinchieri G, Sehgal CM, Feldman MD, Lee WM.

Cancer Res. 2001 Apr 1;61(7):2974-82.

18.

Hypoxia in human intraperitoneal and extremity sarcomas.

Evans SM, Hahn SM, Magarelli DP, Zhang PJ, Jenkins WT, Fraker DL, Hsi RA, McKenna WG, Koch CJ.

Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):587-96.

PMID:
11173159
19.

Detection of hypoxia in human squamous cell carcinoma by EF5 binding.

Evans SM, Hahn S, Pook DR, Jenkins WT, Chalian AA, Zhang P, Stevens C, Weber R, Weinstein G, Benjamin I, Mirza N, Morgan M, Rubin S, McKenna WG, Lord EM, Koch CJ.

Cancer Res. 2000 Apr 1;60(7):2018-24.

20.
21.

Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1.

Evans SM, Kachur AV, Shiue CY, Hustinx R, Jenkins WT, Shive GG, Karp JS, Alavi A, Lord EM, Dolbier WR Jr, Koch CJ.

J Nucl Med. 2000 Feb;41(2):327-36.

22.

Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12.

Gee MS, Koch CJ, Evans SM, Jenkins WT, Pletcher CH Jr, Moore JS, Koblish HK, Lee J, Lord EM, Trinchieri G, Lee WM.

Cancer Res. 1999 Oct 1;59(19):4882-9.

23.

Determining subunit dissociation constants in natural and recombinant proteins.

Manning LR, Dumoulin A, Jenkins WT, Winslow RM, Manning JM.

Methods Enzymol. 1999;306:113-29. No abstract available.

PMID:
10432450
24.

Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts.

Koch CJ, Chasan JE, Jenkins WT, Chan CY, Laughlin KM, Evans SM.

Adv Exp Med Biol. 1998;454:611-8.

PMID:
9889941
25.

Oxygen distributions within R3230Ac tumors growing in dorsal flap window chambers in rats.

Wilson DF, Evans SM, Jenkins WT, Vinogradov SA, Ong E, Dewhirst MW.

Adv Exp Med Biol. 1998;454:603-9.

PMID:
9889940
26.

MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.

Biaglow JE, Manevich Y, Leeper D, Chance B, Dewhirst MW, Jenkins WT, Tuttle SW, Wroblewski K, Glickson JD, Stevens C, Evans SM.

Int J Radiat Oncol Biol Phys. 1998 Nov 1;42(4):871-6.

PMID:
9845113
27.

Three solutions of the protein solubility problem.

Jenkins WT.

Protein Sci. 1998 Feb;7(2):376-82.

28.
29.

Tamoxifen induces hypoxia in MCF-7 xenografts.

Evans SM, Koch CJ, Laughlin KM, Jenkins WT, Van Winkle T, Wilson DF.

Cancer Res. 1997 Nov 15;57(22):5155-61.

30.

Oxygen distribution in the vasculature of mouse tissue in vivo measured using a near infra red phosphor.

Lo LW, Jenkins WT, Vinogradov SA, Evans SM, Wilson DF.

Adv Exp Med Biol. 1997;411:577-83.

PMID:
9269475
31.

Evaluation of the concept of "hypoxic fraction" as a descriptor of tumor oxygenation status.

Evans SM, Jenkins WT, Shapiro M, Koch CJ.

Adv Exp Med Biol. 1997;411:215-25.

PMID:
9269430
32.

Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors.

Laughlin KM, Evans SM, Jenkins WT, Tracy M, Chan CY, Lord EM, Koch CJ.

J Pharmacol Exp Ther. 1996 May;277(2):1049-57.

PMID:
8627516
33.

Subunit dissociations in natural and recombinant hemoglobins.

Manning LR, Jenkins WT, Hess JR, Vandegriff K, Winslow RM, Manning JM.

Protein Sci. 1996 Apr;5(4):775-81.

34.

Noninvasive imaging of the distribution in oxygen in tissue in vivo using near-infrared phosphors.

Vinogradov SA, Lo LW, Jenkins WT, Evans SM, Koch C, Wilson DF.

Biophys J. 1996 Apr;70(4):1609-17.

35.

2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors.

Evans SM, Jenkins WT, Joiner B, Lord EM, Koch CJ.

Cancer Res. 1996 Jan 15;56(2):405-11.

36.
37.
38.

Yeast mitochondrial F1-ATPase--effects of metal ions.

Jenkins WT.

Arch Biochem Biophys. 1994 Aug 15;313(1):89-95.

PMID:
8053693
39.

The pyruvate kinase-coupled assay for ATPases: a critical analysis.

Jenkins WT.

Anal Biochem. 1991 Apr;194(1):136-9.

PMID:
1831011
41.

Two kinetic methods to study the regulation of mammalian hexokinases.

Jenkins WT, Thompson CC.

Anal Biochem. 1989 Mar;177(2):396-401.

PMID:
2729560
42.

Guanine nucleotide regulation of the interconversion of the two-state hepatic glucagon receptor system of rat.

Wyborski RJ, Horwitz EM, Jenkins WT, Mormol JS, Gurd RS.

Arch Biochem Biophys. 1988 May 1;262(2):532-42.

PMID:
2835009
43.

Reactions of dysprosium with adenine nucleotides.

Jenkins WT.

J Inorg Biochem. 1988 Apr;32(4):269-75.

PMID:
3379394
44.

Thermodynamic bookkeeping when nucleotides bind. Applications of the theory of linked functions.

Jenkins WT, Bowman WS.

Biochim Biophys Acta. 1988 Feb 11;932(2):268-76.

PMID:
3342227
45.

Factors affecting the rates at which nucleotides bind to Dowex 1 resin.

Jenkins WT, Schweers LA.

Anal Biochem. 1988 Jan;168(1):202-5.

PMID:
3364713
46.

Reactions of 3'-O-methylpyridoxal 5'-phosphate in aspartate aminotransferase.

Chen VJ, Metzler DE, Jenkins WT.

J Biol Chem. 1987 Oct 25;262(30):14422-7.

47.

The induction of DNA-protein crosslinks in hypoxic cells and their possible contribution to cell lethality.

Meyn RE, vanAnkeren SC, Jenkins WT.

Radiat Res. 1987 Mar;109(3):419-29.

PMID:
3550869
48.

Catalysis of the dephosphorylation of an ATP-molybdate complex by calcium and magnesium ions.

Jenkins WT, Patrick JS.

J Inorg Biochem. 1986 Jul;27(3):163-72.

PMID:
3760857
49.

Radiation damage to DNA in various animal tissues: a comparison of yields and repair in vivo and in vitro.

Meyn RE, Jenkins WT, Murray D.

Basic Life Sci. 1986;38:151-8. No abstract available.

PMID:
2943261

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