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Hyaluronidase-2 Regulates RhoA Signalling, Myofibroblast Contractility and other Key Pro-fibrotic Myofibroblast Functions.

Midgley AC, Woods E, Jenkins R, Brown C, Khalid U, Chavez R, Hascall V, Steadman R, Phillips AO, Meran S.

Am J Pathol. 2020 Mar 19. pii: S0002-9440(20)30133-4. doi: 10.1016/j.ajpath.2020.02.012. [Epub ahead of print]


Concomitant 1p/19q co-deletion and IDH1/2, ATRX, and TP53 mutations within a single clone of "dual-genotype" IDH-mutant infiltrating gliomas.

Zepeda-Mendoza CJ, Vaubel RA, Zarei S, Ida CM, Matthews M, Acree S, Raghunathan A, Giannini C, Jenkins RB.

Acta Neuropathol. 2020 Mar 13. doi: 10.1007/s00401-020-02141-x. [Epub ahead of print] No abstract available.


Notes from the Field: Monkey Bite in a Public Park and Possible Exposure to Herpes B Virus - Thailand, 2018.

Wu AC, Rekant SI, Baca ER, Jenkins RM, Perelygina LM, Hilliard JK, Schmid DS, Leman RF.

MMWR Morb Mortal Wkly Rep. 2020 Mar 6;69(9):247-248. doi: 10.15585/mmwr.mm6909a6. No abstract available.


3 Steps to Cure Pulmonary Fibrosis: Step 1 The Runaway Train or Groundhog Day?

Jenkins RG.

Am J Respir Crit Care Med. 2020 Feb 20. doi: 10.1164/rccm.202002-0260ED. [Epub ahead of print] No abstract available.


Outcome predictors for severely brain-injured patients directly admitted or transferred from emergency departments to a trauma center.

Jenkins R, Morris NA, Haac B, Besien RV, Stein DM, Badjatia N, Medic A, Mester G, Tran QK.

World J Emerg Med. 2020;11(2):120-121. doi: 10.5847/wjem.j.1920-8642.2020.02.010. No abstract available.


Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.

Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C, Barnholtz-Sloan J, Sloan AE, Erickson BJ, Decker PA, Kosel ML, LaChance D, Eckel-Passow J, Jenkins R, Villanueva-Meyer J, Rice T, Wrensch M, Wiencke JK, Oberheim Bush NA, Taylor J, Butowski N, Prados M, Clarke J, Chang S, Chang E, Aghi M, Theodosopoulos P, McDermott M, Berger MS.

JAMA Oncol. 2020 Feb 6. doi: 10.1001/jamaoncol.2019.6143. [Epub ahead of print]


Hyper-realistic Face Masks in a Live Passport-Checking Task.

Robertson DJ, Sanders JG, Towler A, Kramer RSS, Spowage J, Byrne A, Burton AM, Jenkins R.

Perception. 2020 Mar;49(3):298-309. doi: 10.1177/0301006620904614. Epub 2020 Feb 3. No abstract available.


cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas.

Brat DJ, Aldape K, Colman H, Figrarella-Branger D, Fuller GN, Giannini C, Holland EC, Jenkins RB, Kleinschmidt-DeMasters B, Komori T, Kros JM, Louis DN, McLean C, Perry A, Reifenberger G, Sarkar C, Stupp R, van den Bent MJ, von Deimling A, Weller M.

Acta Neuropathol. 2020 Mar;139(3):603-608. doi: 10.1007/s00401-020-02127-9. Epub 2020 Jan 29. No abstract available.


Carbon-Phosphorus Coupling from C^N Cyclometalated AuIII Complexes.

Bonsignore R, Thomas SR, Klooster WT, Coles SJ, Jenkins RL, Bourissou D, Barone G, Casini A.

Chemistry. 2020 Jan 29. doi: 10.1002/chem.201905392. [Epub ahead of print]


A Novel Technique for a Successful Closed Reduction of a Bosworth Fracture-Dislocation of the Ankle.

Fan J, Michelin RM, Jenkins R, Hwang M, French M.

Cureus. 2020 Jan 12;12(1):e6632. doi: 10.7759/cureus.6632.


Socioeconomic risk factors for fatal opioid overdoses in the United States: Findings from the Mortality Disparities in American Communities Study (MDAC).

Altekruse SF, Cosgrove CM, Altekruse WC, Jenkins RA, Blanco C.

PLoS One. 2020 Jan 17;15(1):e0227966. doi: 10.1371/journal.pone.0227966. eCollection 2020.


"There's Just No Way to Help, and They Did." Parents Name Compassionate Care as a New Domain of Quality in Pediatric Home-Based Hospice and Palliative Care.

Thienprayoon R, Grossoehme D, Humphrey L, Pestian T, Frimpong-Manso M, Malcolm H, Kitamura E, Jenkins R, Friebert S.

J Palliat Med. 2019 Dec 27. doi: 10.1089/jpm.2019.0418. [Epub ahead of print]


Facial identity across the lifespan.

Mileva M, Young AW, Jenkins R, Burton AM.

Cogn Psychol. 2020 Feb;116:101260. doi: 10.1016/j.cogpsych.2019.101260. Epub 2019 Dec 20.


Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.

Vaubel RA, Tian S, Remonde D, Schroeder MA, Mladek AC, Kitange GJ, Caron A, Kollmeyer TM, Grove R, Peng S, Carlson BL, Ma DJ, Sarkar G, Evers L, Decker PA, Yan H, Dhruv HD, Berens ME, Wang Q, Marin BM, Klee EW, Califano A, LaChance DH, Eckel-Passow JE, Verhaak RG, Sulman EP, Burns TC, Meyer FB, O'Neill BP, Tran NL, Giannini C, Jenkins RB, Parney IF, Sarkaria JN.

Clin Cancer Res. 2020 Mar 1;26(5):1094-1104. doi: 10.1158/1078-0432.CCR-19-0909. Epub 2019 Dec 18.


Click-Engineered, Bioresponsive, and Versatile Particle-Protein-Dye System.

Burdette MK, Jenkins R, Bandera YP, Jones H, Foulger IK, Dickey A, Nieminen AL, Foulger SH.

ACS Appl Bio Mater. 2019 Aug 19;2(8):3183-3193. doi: 10.1021/acsabm.9b00025. Epub 2019 Jul 1.


Translating CKD Research into Primary Care Practice: a Group-Randomized Study.

Litvin CB, Nietert PJ, Jenkins RG, Wessell AM, Nemeth LS, Ornstein SM.

J Gen Intern Med. 2019 Dec 10. doi: 10.1007/s11606-019-05353-4. [Epub ahead of print]


Welcome to the 16th volume of Future Oncology.

Jenkins R, Gautier L.

Future Oncol. 2020 Jan;16(1):4247-4250. doi: 10.2217/fon-2019-0741. Epub 2019 Dec 4. No abstract available.


What is a rural opioid risk and policy environment?

Jenkins RA, Hagan H.

Int J Drug Policy. 2019 Nov 29:102606. doi: 10.1016/j.drugpo.2019.11.014. [Epub ahead of print] No abstract available.


Sowing Across a State: Development and Delivery of a Grassroots Pediatric Palliative Care Nursing Curriculum.

Weaver MS, Jenkins R, Wichman C, Robinson JE, Potthoff MR, Menicucci T, Vail CA.

J Palliat Care. 2019 Nov 26:825859719889700. doi: 10.1177/0825859719889700. [Epub ahead of print]


Working Up Group 4 Equivocal HER2 Samples Tested by Fluorescence in Situ Hybridization in a Reference Laboratory Setting: Past, Present, and Future.

Geiersbach KB, Meyer RG, Sill DR, Mounajjed T, Chen B, Sukov WR, Jenkins RB.

J Clin Oncol. 2020 Jan 10;38(2):175-176. doi: 10.1200/JCO.19.02482. Epub 2019 Nov 26. No abstract available.


More human than human: a Turing test for photographed faces.

Sanders JG, Ueda Y, Yoshikawa S, Jenkins R.

Cogn Res Princ Implic. 2019 Nov 21;4(1):43. doi: 10.1186/s41235-019-0197-9.


Data resource profile: Adult Psychiatric Morbidity Survey (APMS).

McManus S, Bebbington PE, Jenkins R, Morgan Z, Brown L, Collinson D, Brugha T.

Int J Epidemiol. 2019 Nov 14. pii: dyz224. doi: 10.1093/ije/dyz224. [Epub ahead of print] No abstract available.


Effective In Vivo Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors.

Ipseiz N, Czubala MA, Bart VMT, Davies LC, Jenkins RH, Brennan P, Taylor PR.

Mol Ther Methods Clin Dev. 2019 Oct 18;16:21-31. doi: 10.1016/j.omtm.2019.10.004. eCollection 2020 Mar 13.


Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

Allen RJ, Guillen-Guio B, Oldham JM, Ma SF, Dressen A, Paynton ML, Kraven LM, Obeidat M, Li X, Ng M, Braybrooke R, Molina-Molina M, Hobbs BD, Putman RK, Sakornsakolpat P, Booth HL, Fahy WA, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Whyte MKB, Zhang Y, Kaminski N, Adegunsoye A, Strek ME, Neighbors M, Sheng XR, Gudmundsson G, Gudnason V, Hatabu H, Lederer DJ, Manichaikul A, Newell JD Jr, O'Connor GT, Ortega VE, Xu H, Fingerlin TE, Bossé Y, Hao K, Joubert P, Nickle DC, Sin DD, Timens W, Furniss D, Morris AP, Zondervan KT, Hall IP, Sayers I, Tobin MD, Maher TM, Cho MH, Hunninghake GM, Schwartz DA, Yaspan BL, Molyneaux PL, Flores C, Noth I, Jenkins RG, Wain LV.

Am J Respir Crit Care Med. 2020 Mar 1;201(5):564-574. doi: 10.1164/rccm.201905-1017OC.


Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis.

Saunders CN, Cornish AJ, Kinnersley B, Law PJ, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS.

Neuro Oncol. 2020 Feb 20;22(2):207-215. doi: 10.1093/neuonc/noz209.


Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions.

Park D, Wershof E, Boeing S, Labernadie A, Jenkins RP, George S, Trepat X, Bates PA, Sahai E.

Nat Mater. 2020 Feb;19(2):227-238. doi: 10.1038/s41563-019-0504-3. Epub 2019 Oct 28.


Matrix feedback enables diverse higher-order patterning of the extracellular matrix.

Wershof E, Park D, Jenkins RP, Barry DJ, Sahai E, Bates PA.

PLoS Comput Biol. 2019 Oct 28;15(10):e1007251. doi: 10.1371/journal.pcbi.1007251. eCollection 2019 Oct.


A Photoactivatable Small-Molecule Probe for the In Vivo Capture of Polyketide Intermediates.

Kilgour SL, Jenkins R, Tosin M.

Chemistry. 2019 Oct 16. doi: 10.1002/chem.201903661. [Epub ahead of print]


Desmoplastic Infantile Ganglioglioma: A MAPK Pathway-Driven and Microglia/Macrophage-Rich Neuroepithelial Tumor.

Blessing MM, Blackburn PR, Krishnan C, Harrod VL, Barr Fritcher EG, Zysk CD, Jackson RA, Milosevic D, Nair AA, Davila JI, Balcom JR, Jenkins RB, Halling KC, Kipp BR, Nageswara Rao AA, Laack NN, Daniels DJ, Macon WR, Ida CM.

J Neuropathol Exp Neurol. 2019 Nov 1;78(11):1011-1021. doi: 10.1093/jnen/nlz086.


The Role of Two-Pore Channels in Norepinephrine-Induced [Ca2+]i Rise in Rat Aortic Smooth Muscle Cells and Aorta Contraction.

Trufanov SK, Rybakova EY, Avdonin PP, Tsitrina AA, Zharkikh IL, Goncharov NV, Jenkins RO, Avdonin PV.

Cells. 2019 Sep 25;8(10). pii: E1144. doi: 10.3390/cells8101144.


Improved Drug Delivery to Brain Metastases by Peptide-Mediated Permeabilization of the Blood-Brain Barrier.

Aasen SN, Espedal H, Holte CF, Keunen O, Karlsen TV, Tenstad O, Maherally Z, Miletic H, Hoang T, Eikeland AV, Baghirov H, Olberg DE, Pilkington GJ, Sarkar G, Jenkins RB, Sundstrøm T, Bjerkvig R, Thorsen F.

Mol Cancer Ther. 2019 Nov;18(11):2171-2181. doi: 10.1158/1535-7163.MCT-19-0160. Epub 2019 Aug 29.


Metabolic Profile of Supragingival Plaque Exposed to Arginine and Fluoride.

Nascimento MM, Alvarez AJ, Huang X, Browngardt C, Jenkins R, Sinhoreti MC, Ribeiro APD, Dilbone DA, Richards VP, Garrett TJ, Burne RA.

J Dent Res. 2019 Oct;98(11):1245-1252. doi: 10.1177/0022034519869906. Epub 2019 Aug 27.


What could the future hold for treatment sequencing in cancer medicine? An interview with Angela Märten.

Märten A, Jenkins R.

Future Oncol. 2019 Sep;15(25):2891-2893. doi: 10.2217/fon-2019-0176. Epub 2019 Aug 19.


Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young.

Johnson DR, Giannini C, Jenkins RB, Kim DK, Kaufmann TJ.

Neuroradiology. 2019 Nov;61(11):1327-1332. doi: 10.1007/s00234-019-02269-y. Epub 2019 Aug 9.


The changing spectrum of hypertension in premature infants.

Farnbach K, Iragorri S, Al-Uzri A, Rozansky D, Forbush R, Jenkins R.

J Perinatol. 2019 Nov;39(11):1528-1534. doi: 10.1038/s41372-019-0457-z. Epub 2019 Aug 6.


A four-gene transcript score to predict metastatic-lethal progression in men treated for localized prostate cancer: Development and validation studies.

Cheng A, Zhao S, FitzGerald LM, Wright JL, Kolb S, Karnes RJ, Jenkins RB, Davicioni E, Ostrander EA, Feng Z, Fan JB, Dai JY, Stanford JL.

Prostate. 2019 Oct;79(14):1589-1596. doi: 10.1002/pros.23882. Epub 2019 Aug 2.


Spinal Cord Ependymomas With MYCN Amplification Show Aggressive Clinical Behavior.

Swanson AA, Raghunathan A, Jenkins RB, Messing-Jünger M, Pietsch T, Clarke MJ, Kaufmann TJ, Giannini C.

J Neuropathol Exp Neurol. 2019 Sep 1;78(9):791-797. doi: 10.1093/jnen/nlz064.


Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5' AMP-activated protein kinase signalling in malignant cells.

Austin JA, Jenkins RE, Austin GM, Glenn MA, Dunn K, Scott L, Lucas CM, Clark RE.

Biochem J. 2019 Aug 15;476(15):2255-2269. doi: 10.1042/BCJ20190121.


Molecular profiling of long-term IDH-wildtype glioblastoma survivors.

Burgenske DM, Yang J, Decker PA, Kollmeyer TM, Kosel ML, Mladek AC, Caron AA, Vaubel RA, Gupta SK, Kitange GJ, Sicotte H, Youland RS, Remonde D, Voss JS, Fritcher EGB, Kolsky KL, Ida CM, Meyer FB, Lachance DH, Parney IJ, Kipp BR, Giannini C, Sulman EP, Jenkins RB, Eckel-Passow JE, Sarkaria JN.

Neuro Oncol. 2019 Nov 4;21(11):1458-1469. doi: 10.1093/neuonc/noz129.


Notes from the Field: Targeted Biomonitoring for GenX and Other Per- and Polyfluoroalkyl Substances Following Detection of Drinking Water Contamination - North Carolina, 2018.

Pritchett JR, Rinsky JL, Dittman B, Christensen A, Langley R, Moore Z, Fleischauer AT, Koehler K, Calafat AM, Rogers R, Esters L, Jenkins R, Collins F, Conner D, Breysse P.

MMWR Morb Mortal Wkly Rep. 2019 Jul 26;68(29):647-648. doi: 10.15585/mmwr.mm6829a4. No abstract available.


Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.

Hobbs BD, Putman RK, Araki T, Nishino M, Gudmundsson G, Gudnason V, Eiriksdottir G, Zilhao Nogueira NR, Dupuis J, Xu H, O'Connor GT, Manichaikul A, Nguyen J, Podolanczuk AJ, Madahar P, Rotter JI, Lederer DJ, Barr RG, Rich SS, Ampleford EJ, Ortega VE, Peters SP, O'Neal WK, Newell JD Jr, Bleecker ER, Meyers DA, Allen RJ, Oldham JM, Ma SF, Noth I, Jenkins RG, Maher TM, Hubbard RB, Wain LV, Fingerlin TE, Schwartz DA, Washko GR, Rosas IO, Silverman EK, Hatabu H, Cho MH, Hunninghake GM.

Am J Respir Crit Care Med. 2019 Dec 1;200(11):1402-1413. doi: 10.1164/rccm.201903-0511OC.


Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study.

Maher TM, Stowasser S, Nishioka Y, White ES, Cottin V, Noth I, Selman M, Rohr KB, Michael A, Ittrich C, Diefenbach C, Jenkins RG; INMARK trial investigators.

Lancet Respir Med. 2019 Sep;7(9):771-779. doi: 10.1016/S2213-2600(19)30255-3. Epub 2019 Jul 17.


Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis.

Brook AC, Jenkins RH, Clayton A, Kift-Morgan A, Raby AC, Shephard AP, Mariotti B, Cuff SM, Bazzoni F, Bowen T, Fraser DJ, Eberl M.

Sci Rep. 2019 Jul 12;9(1):10136. doi: 10.1038/s41598-019-46585-y.


Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort.

Organ LA, Duggan AR, Oballa E, Taggart SC, Simpson JK, Kang'ombe AR, Braybrooke R, Molyneaux PL, North B, Karkera Y, Leeming DJ, Karsdal MA, Nanthakumar CB, Fahy WA, Marshall RP, Jenkins RG, Maher TM.

Respir Res. 2019 Jul 12;20(1):148. doi: 10.1186/s12931-019-1118-7.


The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients.

Horbinski C, Ligon KL, Brastianos P, Huse JT, Venere M, Chang S, Buckner J, Cloughesy T, Jenkins RB, Giannini C, Stupp R, Nabors LB, Wen PY, Aldape KJ, Lukas RV, Galanis E, Eberhart CG, Brat DJ, Sarkaria JN.

Neuro Oncol. 2019 Dec 17;21(12):1498-1508. doi: 10.1093/neuonc/noz119.


Characterizing Comorbid Cerebrovascular Insults Among Patients With TBI at a TBI Model Systems Rehabilitation Center.

Jenkins RM, Manche NL, Sima AP, Marwitz JH, Walker WC.

J Head Trauma Rehabil. 2020 Jan/Feb;35(1):E51-E59. doi: 10.1097/HTR.0000000000000505.


Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing.

Lorenzo-Salazar JM, Ma SF, Jou J, Hou PC, Guillen-Guio B, Allen RJ, Jenkins RG, Wain LV, Oldham JM, Noth I, Flores C.

ERJ Open Res. 2019 Jun 10;5(2). pii: 00071-2019. doi: 10.1183/23120541.00071-2019. eCollection 2019 Apr.


Prevalence of non-suicidal self-harm and service contact in England, 2000-14: repeated cross-sectional surveys of the general population.

McManus S, Gunnell D, Cooper C, Bebbington PE, Howard LM, Brugha T, Jenkins R, Hassiotis A, Weich S, Appleby L.

Lancet Psychiatry. 2019 Jul;6(7):573-581. doi: 10.1016/S2215-0366(19)30188-9. Epub 2019 Jun 4.

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