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Items: 1 to 50 of 122

1.

Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia.

Gong S, Sovio U, Aye IL, Gaccioli F, Dopierala J, Johnson MD, Wood AM, Cook E, Jenkins BJ, Koulman A, Casero RA Jr, Constância M, Charnock-Jones DS, Smith GC.

JCI Insight. 2018 Jul 12;3(13). pii: 120723. doi: 10.1172/jci.insight.120723. [Epub ahead of print]

2.

PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress.

Haider A, Wei YC, Lim K, Barbosa AD, Liu CH, Weber U, Mlodzik M, Oras K, Collier S, Hussain MM, Dong L, Patel S, Alvarez-Guaita A, Saudek V, Jenkins BJ, Koulman A, Dymond MK, Hardie RC, Siniossoglou S, Savage DB.

Dev Cell. 2018 May 21;45(4):481-495.e8. doi: 10.1016/j.devcel.2018.04.012. Epub 2018 May 10.

3.

Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells.

Tafreshi M, Guan J, Gorrell RJ, Chew N, Xin Y, Deswaerte V, Rohde M, Daly RJ, Peek RM Jr, Jenkins BJ, Davies EM, Kwok T.

Front Cell Infect Microbiol. 2018 Feb 6;8:22. doi: 10.3389/fcimb.2018.00022. eCollection 2018.

4.

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development.

Hill DG, Yu L, Gao H, Balic JJ, West A, Oshima H, McLeod L, Oshima M, Gallimore A, D'Costa K, Bhathal PS, Sievert W, Ferrero RL, Jenkins BJ, Jones GW.

Int J Cancer. 2018 Jul 1;143(1):167-178. doi: 10.1002/ijc.31298. Epub 2018 Feb 19.

5.

Reviewing the Utility of EUS FNA to Advance Precision Medicine in Pancreatic Cancer.

Berry W, Lundy J, Croagh D, Jenkins BJ.

Cancers (Basel). 2018 Jan 27;10(2). pii: E35. doi: 10.3390/cancers10020035. Review.

6.

Clinical Utility of a STAT3-Regulated miRNA-200 Family Signature with Prognostic Potential in Early Gastric Cancer.

Yu L, Wu D, Gao H, Balic JJ, Tsykin A, Han TS, Liu YD, Kennedy CL, Li JK, Mao JQ, Tan P, Oshima M, Goodall GJ, Jenkins BJ.

Clin Cancer Res. 2018 Mar 15;24(6):1459-1472. doi: 10.1158/1078-0432.CCR-17-2485. Epub 2018 Jan 12.

PMID:
29330205
7.

Immuno-detection of Immature and Bioactive Forms of the Inflammatory Cytokine IL-18.

Jenkins BJ, Deswaerte V.

Methods Mol Biol. 2018;1725:229-235. doi: 10.1007/978-1-4939-7568-6_18.

PMID:
29322421
8.

Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.

Deswaerte V, Nguyen P, West A, Browning AF, Yu L, Ruwanpura SM, Balic J, Livis T, Girard C, Preaudet A, Oshima H, Fung KY, Tye H, Najdovska M, Ernst M, Oshima M, Gabay C, Putoczki T, Jenkins BJ.

Cancer Res. 2018 Mar 1;78(5):1293-1307. doi: 10.1158/0008-5472.CAN-17-1887. Epub 2017 Dec 27.

PMID:
29282220
9.

In vivo evidence that RBM5 is a tumour suppressor in the lung.

Jamsai D, Watkins DN, O'Connor AE, Merriner DJ, Gursoy S, Bird AD, Kumar B, Miller A, Cole TJ, Jenkins BJ, O'Bryan MK.

Sci Rep. 2017 Nov 24;7(1):16323. doi: 10.1038/s41598-017-15874-9.

10.

Time spent in the clinical environment is the most important aspect of medical education - we need to protect it.

England AJ, Jenkins BJ.

Anaesthesia. 2017 Nov;72(11):1306-1311. doi: 10.1111/anae.14049. Epub 2017 Sep 18. No abstract available.

PMID:
28921503
11.

Potential efficacy of interleukin-1β inhibition in lung cancer.

Jenkins BJ.

Lancet. 2017 Oct 21;390(10105):1813-1814. doi: 10.1016/S0140-6736(17)32289-4. Epub 2017 Aug 27. No abstract available.

PMID:
28855076
12.

The view from the top. Is it worth recording for posterity?

Jenkins BJ.

Anaesthesia. 2018 Feb;73(2):151-154. doi: 10.1111/anae.14028. Epub 2017 Aug 22. No abstract available.

PMID:
28832935
13.

Lipidomics Profiling of Human Adipose Tissue Identifies a Pattern of Lipids Associated with Fish Oil Supplementation.

Stanley EG, Jenkins BJ, Walker CG, Koulman A, Browning L, West AL, Calder PC, Jebb SA, Griffin JL.

J Proteome Res. 2017 Sep 1;16(9):3168-3179. doi: 10.1021/acs.jproteome.7b00161. Epub 2017 Aug 16.

PMID:
28587463
14.

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer.

West AC, Tang K, Tye H, Yu L, Deng N, Najdovska M, Lin SJ, Balic JJ, Okochi-Takada E, McGuirk P, Keogh B, McCormack W, Bhathal PS, Reilly M, Oshima M, Ushijima T, Tan P, Jenkins BJ.

Oncogene. 2017 Sep 7;36(36):5134-5144. doi: 10.1038/onc.2017.121. Epub 2017 May 8.

PMID:
28481875
15.

Odd Chain Fatty Acids; New Insights of the Relationship Between the Gut Microbiota, Dietary Intake, Biosynthesis and Glucose Intolerance.

Jenkins BJ, Seyssel K, Chiu S, Pan PH, Lin SY, Stanley E, Ament Z, West JA, Summerhill K, Griffin JL, Vetter W, Autio KJ, Hiltunen K, Hazebrouck S, Stepankova R, Chen CJ, Alligier M, Laville M, Moore M, Kraft G, Cherrington A, King S, Krauss RM, de Schryver E, Van Veldhoven PP, Ronis M, Koulman A.

Sci Rep. 2017 Mar 23;7:44845. doi: 10.1038/srep44845.

16.

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors.

Berry W, Algar E, Kumar B, Desmond C, Swan M, Jenkins BJ, Croagh D.

Int J Cancer. 2017 May 15;140(10):2331-2343. doi: 10.1002/ijc.30648. Epub 2017 Feb 28.

17.

Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling.

Balic JJ, Garbers C, Rose-John S, Yu L, Jenkins BJ.

Cytokine. 2017 Apr;92:118-123. doi: 10.1016/j.cyto.2017.01.015. Epub 2017 Feb 1.

PMID:
28160627
18.

Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.

Miller A, McLeod L, Alhayyani S, Szczepny A, Watkins DN, Chen W, Enriori P, Ferlin W, Ruwanpura S, Jenkins BJ.

Oncogene. 2017 May 25;36(21):3059-3066. doi: 10.1038/onc.2016.437. Epub 2016 Nov 28.

PMID:
27893707
19.

Laboratory evaluation of a novel anaesthesia delivery device.

Paul A, Clark JN, Salama IE, Jenkins BJ, Goodwin N, Wilkes AR, Mahoney PF, Hall JE.

Anaesthesia. 2017 Jan;72(1):63-72. doi: 10.1111/anae.13625. Epub 2016 Oct 26.

20.

Transcriptional regulation of inflammasome-associated pattern recognition receptors, and the relevance to disease pathogenesis.

Deswaerte V, Ruwanpura SM, Jenkins BJ.

Mol Immunol. 2017 Jun;86:3-9. doi: 10.1016/j.molimm.2016.09.023. Epub 2016 Sep 30. Review.

PMID:
27697299
21.

Murine Oncostatin M Acts via Leukemia Inhibitory Factor Receptor to Phosphorylate Signal Transducer and Activator of Transcription 3 (STAT3) but Not STAT1, an Effect That Protects Bone Mass.

Walker EC, Johnson RW, Hu Y, Brennan HJ, Poulton IJ, Zhang JG, Jenkins BJ, Smyth GK, Nicola NA, Sims NA.

J Biol Chem. 2016 Oct 7;291(41):21703-21716. Epub 2016 Aug 18.

22.

Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.

Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, Alhayyani S, Tate MD, Deswaerte V, Brooks GD, Bozinovski S, MacDonald M, Garbers C, King PT, Bardin PG, Vlahos R, Rose-John S, Anderson GP, Jenkins BJ.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1494-1505.

PMID:
27373892
23.
24.

Characterization of a Plasmodium falciparum Orthologue of the Yeast Ubiquinone-Binding Protein, Coq10p.

Jenkins BJ, Daly TM, Morrisey JM, Mather MW, Vaidya AB, Bergman LW.

PLoS One. 2016 Mar 25;11(3):e0152197. doi: 10.1371/journal.pone.0152197. eCollection 2016.

25.

Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.

Maeda Y, Echizen K, Oshima H, Yu L, Sakulsak N, Hirose O, Yamada Y, Taniguchi T, Jenkins BJ, Saya H, Oshima M.

Cancer Prev Res (Phila). 2016 Mar;9(3):253-63. doi: 10.1158/1940-6207.CAPR-15-0315. Epub 2016 Feb 17.

26.

Investigating the Role of Toll-Like Receptors in Mouse Models of Gastric Cancer.

West AC, Jenkins BJ.

Methods Mol Biol. 2016;1390:427-49. doi: 10.1007/978-1-4939-3335-8_25.

PMID:
26803643
27.

IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.

Brooks GD, McLeod L, Alhayyani S, Miller A, Russell PA, Ferlin W, Rose-John S, Ruwanpura S, Jenkins BJ.

Cancer Res. 2016 Feb 15;76(4):866-76. doi: 10.1158/0008-5472.CAN-15-2388. Epub 2016 Jan 7.

28.

Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.

Jones GW, Bombardieri M, Greenhill CJ, McLeod L, Nerviani A, Rocher-Ros V, Cardus A, Williams AS, Pitzalis C, Jenkins BJ, Jones SA.

J Exp Med. 2015 Oct 19;212(11):1793-802. doi: 10.1084/jem.20132307. Epub 2015 Sep 28.

29.

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

Bozinovski S, Seow HJ, Chan SP, Anthony D, McQualter J, Hansen M, Jenkins BJ, Anderson GP, Vlahos R.

Clin Sci (Lond). 2015 Nov;129(9):785-96. doi: 10.1042/CS20140703. Epub 2015 Jul 1.

30.

Inflammatory and non-inflammatory roles for Toll-like receptors in gastrointestinal cancer.

West AC, Jenkins BJ.

Curr Pharm Des. 2015;21(21):2968-77. Review.

PMID:
26004414
31.

Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis.

Jones GW, McLeod L, Kennedy CL, Bozinovski S, Najdovska M, Jenkins BJ.

Atherosclerosis. 2015 Feb;238(2):321-8. doi: 10.1016/j.atherosclerosis.2014.12.037. Epub 2014 Dec 23.

PMID:
25545330
32.

Transcriptional regulation of pattern recognition receptors by Jak/STAT signaling, and the implications for disease pathogenesis.

Jenkins BJ.

J Interferon Cytokine Res. 2014 Oct;34(10):750-8. doi: 10.1089/jir.2014.0081. Epub 2014 Jul 22. Review.

PMID:
25051239
33.

STAT1 plays a role in TLR signal transduction and inflammatory responses.

Luu K, Greenhill CJ, Majoros A, Decker T, Jenkins BJ, Mansell A.

Immunol Cell Biol. 2014 Oct;92(9):761-9. doi: 10.1038/icb.2014.51. Epub 2014 Jul 15.

PMID:
25027037
34.

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling.

Luo L, Wall AA, Yeo JC, Condon ND, Norwood SJ, Schoenwaelder S, Chen KW, Jackson S, Jenkins BJ, Hartland EL, Schroder K, Collins BM, Sweet MJ, Stow JL.

Nat Commun. 2014 Jul 15;5:4407. doi: 10.1038/ncomms5407.

PMID:
25022365
35.

Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.

Miller A, Brooks GD, McLeod L, Ruwanpura S, Jenkins BJ.

Oncogene. 2015 Mar 19;34(12):1510-9. doi: 10.1038/onc.2014.99. Epub 2014 Apr 14.

PMID:
24727895
36.

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.

Ruwanpura SM, McLeod L, Brooks GD, Bozinovski S, Vlahos R, Longano A, Bardin PG, Anderson GP, Jenkins BJ.

Respirology. 2014 Apr;19(3):419-27. doi: 10.1111/resp.12243. Epub 2014 Feb 10.

37.

Interleukin-6 signaling drives fibrosis in unresolved inflammation.

Fielding CA, Jones GW, McLoughlin RM, McLeod L, Hammond VJ, Uceda J, Williams AS, Lambie M, Foster TL, Liao CT, Rice CM, Greenhill CJ, Colmont CS, Hams E, Coles B, Kift-Morgan A, Newton Z, Craig KJ, Williams JD, Williams GT, Davies SJ, Humphreys IR, O'Donnell VB, Taylor PR, Jenkins BJ, Topley N, Jones SA.

Immunity. 2014 Jan 16;40(1):40-50. doi: 10.1016/j.immuni.2013.10.022. Epub 2014 Jan 9.

38.

Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice.

Ruwanpura SM, McLeod L, Lilja AR, Brooks G, Dousha LF, Seow HJ, Bozinovski S, Vlahos R, Hertzog PJ, Anderson GP, Jenkins BJ.

PLoS One. 2013 Oct 29;8(10):e78095. doi: 10.1371/journal.pone.0078095. eCollection 2013.

39.

Inflammation and gastrointestinal cancer: an overview.

Marusawa H, Jenkins BJ.

Cancer Lett. 2014 Apr 10;345(2):153-6. doi: 10.1016/j.canlet.2013.08.025. Epub 2013 Aug 24. Review.

PMID:
23981579
40.

Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A.

Jones GW, Greenhill CJ, Williams JO, Nowell MA, Williams AS, Jenkins BJ, Jones SA.

Ann Rheum Dis. 2013 Oct;72(10):1738-42. doi: 10.1136/annrheumdis-2013-203771. Epub 2013 Jul 26.

41.

Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.

Carow B, Reuschl AK, Gavier-Widén D, Jenkins BJ, Ernst M, Yoshimura A, Chambers BJ, Rottenberg ME.

PLoS Pathog. 2013;9(7):e1003442. doi: 10.1371/journal.ppat.1003442. Epub 2013 Jul 4.

42.

Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis.

Kennedy CL, Najdovska M, Tye H, McLeod L, Yu L, Jarnicki A, Bhathal PS, Putoczki T, Ernst M, Jenkins BJ.

Oncogene. 2014 May 8;33(19):2540-6. doi: 10.1038/onc.2013.205. Epub 2013 Jun 3.

PMID:
23728346
43.

Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers.

Tye H, Jenkins BJ.

Cancer Sci. 2013 Sep;104(9):1139-45. doi: 10.1111/cas.12205. Epub 2013 Jun 24. Review.

44.

Dangerous liaisons between interleukin-6 cytokine and toll-like receptor families: a potent combination in inflammation and cancer.

Mansell A, Jenkins BJ.

Cytokine Growth Factor Rev. 2013 Jun;24(3):249-56. doi: 10.1016/j.cytogfr.2013.03.007. Epub 2013 May 3. Review.

PMID:
23643515
45.

Nucleotide oligomerization domain 1 enhances IFN-γ signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity.

Allison CC, Ferrand J, McLeod L, Hassan M, Kaparakis-Liaskos M, Grubman A, Bhathal PS, Dev A, Sievert W, Jenkins BJ, Ferrero RL.

J Immunol. 2013 Apr 1;190(7):3706-15. doi: 10.4049/jimmunol.1200591. Epub 2013 Mar 4.

46.

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

Tye H, Kennedy CL, Najdovska M, McLeod L, McCormack W, Hughes N, Dev A, Sievert W, Ooi CH, Ishikawa TO, Oshima H, Bhathal PS, Parker AE, Oshima M, Tan P, Jenkins BJ.

Cancer Cell. 2012 Oct 16;22(4):466-78. doi: 10.1016/j.ccr.2012.08.010.

47.

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.

Ruwanpura SM, McLeod L, Miller A, Jones J, Vlahos R, Ramm G, Longano A, Bardin PG, Bozinovski S, Anderson GP, Jenkins BJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L627-39. doi: 10.1152/ajplung.00285.2011. Epub 2012 Jan 20.

48.

The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.

Kennedy CL, Najdovska M, Jones GW, McLeod L, Hughes NR, Allison C, Ooi CH, Tan P, Ferrero RL, Jones SA, Dev A, Sievert W, Bhathal PS, Jenkins BJ.

J Pathol. 2011 Oct;225(2):255-64. doi: 10.1002/path.2933. Epub 2011 Jun 27.

PMID:
21710691
49.

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

Greenhill CJ, Gould J, Ernst M, Jarnicki A, Hertzog PJ, Mansell A, Jenkins BJ.

Immunol Cell Biol. 2012 May;90(5):559-63. doi: 10.1038/icb.2011.56. Epub 2011 Jun 14. Erratum in: Immunol Cell Biol. 2012 May;90(5):564. Jarnicki, Andrew [added].

PMID:
21670738
50.

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

Ruwanpura SM, McLeod L, Miller A, Jones J, Bozinovski S, Vlahos R, Ernst M, Armes J, Bardin PG, Anderson GP, Jenkins BJ.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):720-30. doi: 10.1165/rcmb.2010-0462OC. Epub 2011 Feb 4.

PMID:
21297079

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