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Items: 24


Antibodies to the conserved region of the M protein and a streptococcal superantigen cooperatively resolve toxic shock-like syndrome in HLA-humanized mice.

Pandey M, Calcutt A, Ozberk V, Chen Z, Croxen M, Powell J, Langshaw E, Mills JL, Jen FE, McCluskey J, Robson J, Tyrrell GJ, Good MF.

Sci Adv. 2019 Sep 4;5(9):eaax3013. doi: 10.1126/sciadv.aax3013. eCollection 2019 Sep.


Glycointeractome of Neisseria gonorrhoeae: Identification of Host Glycans Targeted by the Gonococcus To Facilitate Adherence to Cervical and Urethral Epithelial Cells.

Semchenko EA, Everest-Dass AV, Jen FE, Mubaiwa TD, Day CJ, Seib KL.

MBio. 2019 Jul 9;10(4). pii: e01339-19. doi: 10.1128/mBio.01339-19.


Screening DNA Repeat Tracts of Phase Variable Genes by Fragment Analysis.

Jen FE, Seib KL, Tan A.

Methods Mol Biol. 2019;1969:93-104. doi: 10.1007/978-1-4939-9202-7_6.


The Neisseria gonorrhoeae Methionine Sulfoxide Reductase (MsrA/B) Is a Surface Exposed, Immunogenic, Vaccine Candidate.

Jen FE, Semchenko EA, Day CJ, Seib KL, Jennings MP.

Front Immunol. 2019 Feb 6;10:137. doi: 10.3389/fimmu.2019.00137. eCollection 2019.


Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: a new strategy to generate antimicrobial peptides.

Zhan J, Jia H, Semchenko EA, Bian Y, Zhou AM, Li Z, Yang Y, Wang J, Sarkar S, Totsika M, Blanchard H, Jen FE, Ye Q, Haselhorst T, Jennings MP, Seib KL, Zhou Y.

FASEB J. 2019 Feb;33(2):2095-2104. doi: 10.1096/fj.201700613RR. Epub 2018 Sep 27.


Epigenetic Regulation Alters Biofilm Architecture and Composition in Multiple Clinical Isolates of Nontypeable Haemophilus influenzae.

Brockman KL, Azzari PN, Branstool MT, Atack JM, Schulz BL, Jen FE, Jennings MP, Bakaletz LO.

MBio. 2018 Sep 18;9(5). pii: e01682-18. doi: 10.1128/mBio.01682-18.


Nontypeable Haemophilus influenzae Lipooligosaccharide Expresses a Terminal Ketodeoxyoctanoate In Vivo, Which Can Be Used as a Target for Bactericidal Antibody.

Apicella MA, Coffin J, Ketterer M, Post DMB, Day CJ, Jen FE, Jennings MP.

MBio. 2018 Jul 31;9(4). pii: e01401-18. doi: 10.1128/mBio.01401-18.


Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria.

Seib KL, Jen FE, Scott AL, Tan A, Jennings MP.

Pathog Dis. 2017 Aug 31;75(6). doi: 10.1093/femspd/ftx080.


Refinement of immunizing antigens to produce functional blocking antibodies against the AniA nitrite reductase of Neisseria gonorrhoeae.

Shewell LK, Jen FE, Jennings MP.

PLoS One. 2017 Aug 3;12(8):e0182555. doi: 10.1371/journal.pone.0182555. eCollection 2017.


The glycointeractome of serogroup B Neisseria meningitidis strain MC58.

Mubaiwa TD, Hartley-Tassell LE, Semchenko EA, Jen FE, Srikhanta YN, Day CJ, Jennings MP, Seib KL.

Sci Rep. 2017 Jul 18;7(1):5693. doi: 10.1038/s41598-017-05894-w.


Structure aided design of a Neu5Gc specific lectin.

Day CJ, Paton AW, Higgins MA, Shewell LK, Jen FE, Schulz BL, Herdman BP, Paton JC, Jennings MP.

Sci Rep. 2017 May 4;7(1):1495. doi: 10.1038/s41598-017-01522-9.


Neisseria meningitidis Lacking the Major Porins PorA and PorB Is Viable and Modulates Apoptosis and the Oxidative Burst of Neutrophils.

Peak IR, Chen A, Jen FE, Jennings C, Schulz BL, Saunders NJ, Khan A, Seifert HS, Jennings MP.

J Proteome Res. 2016 Aug 5;15(8):2356-65. doi: 10.1021/acs.jproteome.5b00938. Epub 2016 Jul 21.


A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae.

Atack JM, Srikhanta YN, Fox KL, Jurcisek JA, Brockman KL, Clark TA, Boitano M, Power PM, Jen FE, McEwan AG, Grimmond SM, Smith AL, Barenkamp SJ, Korlach J, Bakaletz LO, Jennings MP.

Nat Commun. 2015 Jul 28;6:7828. doi: 10.1038/ncomms8828.


A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria.

Jen FE, Djoko KY, Bent SJ, Day CJ, McEwan AG, Jennings MP.

FASEB J. 2015 Sep;29(9):3828-38. doi: 10.1096/fj.15-270751. Epub 2015 Jun 1.


Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N(6)-adenine DNA methyltransferases of Neisseria meningitidis.

Seib KL, Jen FE, Tan A, Scott AL, Kumar R, Power PM, Chen LT, Wu HJ, Wang AH, Hill DM, Luyten YA, Morgan RD, Roberts RJ, Maiden MC, Boitano M, Clark TA, Korlach J, Rao DN, Jennings MP.

Nucleic Acids Res. 2015 Apr 30;43(8):4150-62. doi: 10.1093/nar/gkv219. Epub 2015 Apr 6.


ModM DNA methyltransferase methylome analysis reveals a potential role for Moraxella catarrhalis phasevarions in otitis media.

Blakeway LV, Power PM, Jen FE, Worboys SR, Boitano M, Clark TA, Korlach J, Bakaletz LO, Jennings MP, Peak IR, Seib KL.

FASEB J. 2014 Dec;28(12):5197-207. doi: 10.1096/fj.14-256578. Epub 2014 Sep 2.


Phasevarions mediate epigenetic regulation of antimicrobial susceptibility in Neisseria meningitidis.

Jen FE, Seib KL, Jennings MP.

Antimicrob Agents Chemother. 2014 Jul;58(7):4219-21. doi: 10.1128/AAC.00004-14. Epub 2014 Apr 28.


A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation.

Christie MP, Simersk√° P, Jen FE, Hussein WM, Rawi MF, Hartley-Tassell LE, Day CJ, Jennings MP, Toth I.

PLoS One. 2014 Apr 15;9(4):e95024. doi: 10.1371/journal.pone.0095024. eCollection 2014.


Role of Neisseria meningitidis PorA and PorB expression in antimicrobial susceptibility.

Peak IR, Jennings CD, Jen FE, Jennings MP.

Antimicrob Agents Chemother. 2014;58(1):614-6. doi: 10.1128/AAC.02506-12. Epub 2013 Oct 21. No abstract available.


Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells.

Jen FE, Warren MJ, Schulz BL, Power PM, Swords WE, Weiser JN, Apicella MA, Edwards JL, Jennings MP.

PLoS Pathog. 2013;9(5):e1003377. doi: 10.1371/journal.ppat.1003377. Epub 2013 May 16.


Identification of bacterial protein O-oligosaccharyltransferases and their glycoprotein substrates.

Schulz BL, Jen FE, Power PM, Jones CE, Fox KL, Ku SC, Blanchfield JT, Jennings MP.

PLoS One. 2013 May 3;8(5):e62768. doi: 10.1371/journal.pone.0062768. Print 2013.


Recombinant truncated AniA of pathogenic Neisseria elicits a non-native immune response and functional blocking antibodies.

Shewell LK, Ku SC, Schulz BL, Jen FE, Mubaiwa TD, Ketterer MR, Apicella MA, Jennings MP.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):215-20. doi: 10.1016/j.bbrc.2012.12.132. Epub 2013 Jan 9.


Substrate recognition of a structure motif for phosphorylcholine post-translational modification in Neisseria meningitidis.

Jen FE, Jones CE, Wilson JC, Schulz BL, Jennings MP.

Biochem Biophys Res Commun. 2013 Feb 22;431(4):808-14. doi: 10.1016/j.bbrc.2012.12.088. Epub 2012 Dec 27.


Neisseria gonorrhoeae pilin glycan contributes to CR3 activation during challenge of primary cervical epithelial cells.

Jennings MP, Jen FE, Roddam LF, Apicella MA, Edwards JL.

Cell Microbiol. 2011 Jun;13(6):885-96. doi: 10.1111/j.1462-5822.2011.01586.x. Epub 2011 Mar 4.

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