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Items: 1 to 50 of 70

1.

Resistance to piperacillin/tazobactam in Escherichia coli resulting from extensive IS26-associated gene amplification of blaTEM-1.

Hansen KH, Andreasen MR, Pedersen MS, Westh H, Jelsbak L, Schønning K.

J Antimicrob Chemother. 2019 Aug 14. pii: dkz349. doi: 10.1093/jac/dkz349. [Epub ahead of print]

PMID:
31411684
2.

Complete Genome Sequence of a Bioactive Pseudomonas sp. Strain, DTU12.3, Isolated from Soil in Denmark.

Sazinas P, Aune MI, Fischer MH, Lauritsen JG, Gram L, Jelsbak L.

Microbiol Resour Announc. 2019 Apr 18;8(16). pii: e00121-19. doi: 10.1128/MRA.00121-19.

3.

Within-Host Adaptation Mediated by Intergenic Evolution in Pseudomonas aeruginosa.

Khademi SMH, Sazinas P, Jelsbak L.

Genome Biol Evol. 2019 May 1;11(5):1385-1397. doi: 10.1093/gbe/evz083.

4.

The SPI-19 encoded type-six secretion-systems (T6SS) of Salmonella enterica serovars Gallinarum and Dublin play different roles during infection.

Schroll C, Huang K, Ahmed S, Kristensen BM, Pors SE, Jelsbak L, Lemire S, Thomsen LE, Christensen JP, Jensen PR, Olsen JE.

Vet Microbiol. 2019 Mar;230:23-31. doi: 10.1016/j.vetmic.2019.01.006. Epub 2019 Jan 7.

PMID:
30827393
5.

Putrescine biosynthesis and export genes are essential for normal growth of avian pathogenic Escherichia coli.

Guerra PR, Herrero-Fresno A, Ladero V, Redruello B, Dos Santos TP, Spiegelhauer MR, Jelsbak L, Olsen JE.

BMC Microbiol. 2018 Dec 27;18(1):226. doi: 10.1186/s12866-018-1355-9.

6.

HldE Is Important for Virulence Phenotypes in Enterotoxigenic Escherichia coli.

Maigaard Hermansen GM, Boysen A, Krogh TJ, Nawrocki A, Jelsbak L, Møller-Jensen J.

Front Cell Infect Microbiol. 2018 Aug 7;8:253. doi: 10.3389/fcimb.2018.00253. eCollection 2018.

7.

A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations.

Folkvardsen DB, Norman A, Andersen ÅB, Rasmussen EM, Lillebaek T, Jelsbak L.

Sci Rep. 2018 Aug 8;8(1):11869. doi: 10.1038/s41598-018-30363-3.

8.

Intergenic evolution during host adaptation increases expression of the metallophore pseudopaline in Pseudomonas aeruginosa.

Hermansen GMM, Hansen ML, Khademi SMH, Jelsbak L.

Microbiology. 2018 Aug;164(8):1038-1047. doi: 10.1099/mic.0.000687. Epub 2018 Jul 3.

PMID:
29969091
9.

Transcriptomic profiling of interacting nasal staphylococci species reveals global changes in gene and non-coding RNA expression.

Hermansen GMM, Sazinas P, Kofod D, Millard A, Andersen PS, Jelsbak L.

FEMS Microbiol Lett. 2018 Mar 1;365(5). doi: 10.1093/femsle/fny004.

PMID:
29325106
10.

Application of RNA-seq and Bioimaging Methods to Study Microbe-Microbe Interactions and Their Effects on Biofilm Formation and Gene Expression.

Amador CI, Sternberg C, Jelsbak L.

Methods Mol Biol. 2018;1734:131-158. doi: 10.1007/978-1-4939-7604-1_12.

PMID:
29288452
11.

Genomic Epidemiology of a Major Mycobacterium tuberculosis Outbreak: Retrospective Cohort Study in a Low-Incidence Setting Using Sparse Time-Series Sampling.

Folkvardsen DB, Norman A, Andersen ÅB, Michael Rasmussen E, Jelsbak L, Lillebaek T.

J Infect Dis. 2017 Aug 1;216(3):366-374. doi: 10.1093/infdis/jix298.

PMID:
28666374
12.

SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients.

Lauridsen RK, Sommer LM, Johansen HK, Rindzevicius T, Molin S, Jelsbak L, Engelsen SB, Boisen A.

Sci Rep. 2017 Mar 28;7:45264. doi: 10.1038/srep45264.

13.

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.

Bartell JA, Blazier AS, Yen P, Thøgersen JC, Jelsbak L, Goldberg JB, Papin JA.

Nat Commun. 2017 Mar 7;8:14631. doi: 10.1038/ncomms14631.

14.

Substantial molecular evolution and mutation rates in prolonged latent Mycobacterium tuberculosis infection in humans.

Lillebaek T, Norman A, Rasmussen EM, Marvig RL, Folkvardsen DB, Andersen ÅB, Jelsbak L.

Int J Med Microbiol. 2016 Nov;306(7):580-585. doi: 10.1016/j.ijmm.2016.05.017. Epub 2016 May 28.

PMID:
27296510
15.

Biofilm as a production platform for heterologous production of rhamnolipids by the non-pathogenic strain Pseudomonas putida KT2440.

Wigneswaran V, Nielsen KF, Sternberg C, Jensen PR, Folkesson A, Jelsbak L.

Microb Cell Fact. 2016 Oct 24;15(1):181.

16.

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions.

Jochumsen N, Marvig RL, Damkiær S, Jensen RL, Paulander W, Molin S, Jelsbak L, Folkesson A.

Nat Commun. 2016 Oct 3;7:13002. doi: 10.1038/ncomms13002.

17.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

18.

The In Vitro Redundant Enzymes PurN and PurT Are Both Essential for Systemic Infection of Mice in Salmonella enterica Serovar Typhimurium.

Jelsbak L, Mortensen MIB, Kilstrup M, Olsen JE.

Infect Immun. 2016 Jun 23;84(7):2076-2085. doi: 10.1128/IAI.00182-16. Print 2016 Jul.

19.

Application of Whole-Genome Sequencing Data for O-Specific Antigen Analysis and In Silico Serotyping of Pseudomonas aeruginosa Isolates.

Thrane SW, Taylor VL, Lund O, Lam JS, Jelsbak L.

J Clin Microbiol. 2016 Jul;54(7):1782-1788. doi: 10.1128/JCM.00349-16. Epub 2016 Apr 20.

20.

Utilization and control of ecological interactions in polymicrobial infections and community-based microbial cell factories.

Wigneswaran V, Amador CI, Jelsbak L, Sternberg C, Jelsbak L.

F1000Res. 2016 Mar 31;5. pii: F1000 Faculty Rev-421. doi: 10.12688/f1000research.7876.1. eCollection 2016. Review.

21.

A Bacteriophage-Acquired O-Antigen Polymerase (Wzyβ) from P. aeruginosa Serotype O16 Performs a Varied Mechanism Compared to Its Cognate Wzyα.

Taylor VL, Hoage JF, Thrane SW, Huszczynski SM, Jelsbak L, Lam JS.

Front Microbiol. 2016 Mar 31;7:393. doi: 10.3389/fmicb.2016.00393. eCollection 2016.

22.

Multiple roles of putrescine and spermidine in stress resistance and virulence of Salmonella enterica serovar Typhimurium.

Espinel IC, Guerra PR, Jelsbak L.

Microb Pathog. 2016 Jun;95:117-123. doi: 10.1016/j.micpath.2016.03.008. Epub 2016 Apr 1.

PMID:
27041598
23.

Salmonella Typhimurium undergoes distinct genetic adaption during chronic infections of mice.

Søndberg E, Jelsbak L.

BMC Microbiol. 2016 Mar 8;16:30. doi: 10.1186/s12866-016-0646-2.

24.

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin.

Wassermann T, Meinike Jørgensen K, Ivanyshyn K, Bjarnsholt T, Khademi SM, Jelsbak L, Høiby N, Ciofu O.

Microbiology. 2016 May;162(5):865-75. doi: 10.1099/mic.0.000273. Epub 2016 Mar 7.

PMID:
26953154
25.

Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate.

Norman A, Ciofu O, Amador CI, Høiby N, Jelsbak L.

Genome Announc. 2016 Feb 25;4(1). pii: e00008-16. doi: 10.1128/genomeA.00008-16.

26.

Highly expressed amino acid biosynthesis genes revealed by global gene expression analysis of Salmonella enterica serovar Enteritidis during growth in whole egg are not essential for this growth.

Jakočiūnė D, Herrero-Fresno A, Jelsbak L, Olsen JE.

Int J Food Microbiol. 2016 May 2;224:40-6. doi: 10.1016/j.ijfoodmicro.2016.02.015. Epub 2016 Feb 24.

PMID:
26945769
27.

Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction.

Frydenlund Michelsen C, Hossein Khademi SM, Krogh Johansen H, Ingmer H, Dorrestein PC, Jelsbak L.

ISME J. 2016 Jun;10(6):1323-36. doi: 10.1038/ismej.2015.220. Epub 2015 Dec 18.

28.

Antibiotic combination therapy can select for broad-spectrum multidrug resistance in Pseudomonas aeruginosa.

Vestergaard M, Paulander W, Marvig RL, Clasen J, Jochumsen N, Molin S, Jelsbak L, Ingmer H, Folkesson A.

Int J Antimicrob Agents. 2016 Jan;47(1):48-55. doi: 10.1016/j.ijantimicag.2015.09.014. Epub 2015 Oct 25.

PMID:
26597931
29.

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium.

Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel É, Grimwood K, Hancock RE, Harrison JJ, Heeb S, Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S, Loman N, Malouin F, Manos J, McArthur AG, McKeown J, Milot J, Naghra H, Nguyen D, Pereira SK, Perron GG, Pirnay JP, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC.

Front Microbiol. 2015 Sep 29;6:1036. doi: 10.3389/fmicb.2015.01036. eCollection 2015.

30.

The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters.

Thrane SW, Taylor VL, Freschi L, Kukavica-Ibrulj I, Boyle B, Laroche J, Pirnay JP, Lévesque RC, Lam JS, Jelsbak L.

MBio. 2015 Sep 22;6(5):e01396-15. doi: 10.1128/mBio.01396-15.

31.

Bacteriocin-mediated competition in cystic fibrosis lung infections.

Ghoul M, West SA, Johansen HK, Molin S, Harrison OB, Maiden MC, Jelsbak L, Bruce JB, Griffin AS.

Proc Biol Sci. 2015 Sep 7;282(1814). doi: 10.1098/rspb.2015.0972.

32.

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients.

Marvig RL, Sommer LM, Jelsbak L, Molin S, Johansen HK.

Future Microbiol. 2015;10(4):599-611. doi: 10.2217/fmb.15.3. Review.

PMID:
25865196
33.

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa.

Markussen T, Marvig RL, Gómez-Lozano M, Aanæs K, Burleigh AE, Høiby N, Johansen HK, Molin S, Jelsbak L.

MBio. 2014 Sep 16;5(5):e01592-14. doi: 10.1128/mBio.01592-14.

34.

Staphylococcus aureus alters growth activity, autolysis, and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage.

Michelsen CF, Christensen AM, Bojer MS, Høiby N, Ingmer H, Jelsbak L.

J Bacteriol. 2014 Nov;196(22):3903-11. doi: 10.1128/JB.02006-14. Epub 2014 Sep 2.

35.

CTX-M-1 β-lactamase expression in Escherichia coli is dependent on cefotaxime concentration, growth phase and gene location.

Kjeldsen TS, Overgaard M, Nielsen SS, Bortolaia V, Jelsbak L, Sommer M, Guardabassi L, Olsen JE.

J Antimicrob Chemother. 2015 Jan;70(1):62-70. doi: 10.1093/jac/dku332. Epub 2014 Sep 1.

PMID:
25182062
36.

Identification of metabolic pathways essential for fitness of Salmonella Typhimurium in vivo.

Jelsbak L, Hartman H, Schroll C, Rosenkrantz JT, Lemire S, Wallrodt I, Thomsen LE, Poolman M, Kilstrup M, Jensen PR, Olsen JE.

PLoS One. 2014 Jul 3;9(7):e101869. doi: 10.1371/journal.pone.0101869. eCollection 2014.

37.

Within-host evolution of Pseudomonas aeruginosa reveals adaptation toward iron acquisition from hemoglobin.

Marvig RL, Damkiær S, Khademi SM, Markussen TM, Molin S, Jelsbak L.

MBio. 2014 May 6;5(3):e00966-14. doi: 10.1128/mBio.00966-14.

38.

Identification of potential drug targets in Salmonella enterica sv. Typhimurium using metabolic modelling and experimental validation.

Hartman HB, Fell DA, Rossell S, Jensen PR, Woodward MJ, Thorndahl L, Jelsbak L, Olsen JE, Raghunathan A, Daefler S, Poolman MG.

Microbiology. 2014 Jun;160(Pt 6):1252-1266. doi: 10.1099/mic.0.076091-0. Epub 2014 Apr 28.

PMID:
24777662
39.

Removal of the phage-shock protein PspB causes reduction of virulence in Salmonella enterica serovar Typhimurium independently of NRAMP1.

Wallrodt I, Jelsbak L, Thomsen LE, Brix L, Lemire S, Gautier L, Nielsen DS, Jovanovic G, Buck M, Olsen JE.

J Med Microbiol. 2014 Jun;63(Pt 6):788-95. doi: 10.1099/jmm.0.072223-0. Epub 2014 Apr 8.

PMID:
24713356
40.

Polyamines are essential for virulence in Salmonella enterica serovar Gallinarum despite evolutionary decay of polyamine biosynthesis genes.

Schroll C, Christensen JP, Christensen H, Pors SE, Thorndahl L, Jensen PR, Olsen JE, Jelsbak L.

Vet Microbiol. 2014 May 14;170(1-2):144-50. doi: 10.1016/j.vetmic.2014.01.034. Epub 2014 Feb 8.

PMID:
24602405
41.

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy.

Marvig RL, Jochumsen N, Johansen HK, Høiby N, Molin S, Sommer MO, Jelsbak L, Folkesson A.

Genome Announc. 2013 Oct 17;1(5). pii: e00804-13. doi: 10.1128/genomeA.00804-13.

42.

Archetypal analysis of diverse Pseudomonas aeruginosa transcriptomes reveals adaptation in cystic fibrosis airways.

Thøgersen JC, Mørup M, Damkiær S, Molin S, Jelsbak L.

BMC Bioinformatics. 2013 Sep 23;14:279. doi: 10.1186/1471-2105-14-279.

43.

Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators.

Marvig RL, Johansen HK, Molin S, Jelsbak L.

PLoS Genet. 2013;9(9):e1003741. doi: 10.1371/journal.pgen.1003741. Epub 2013 Sep 5.

44.

The putative thiosulfate sulfurtransferases PspE and GlpE contribute to virulence of Salmonella Typhimurium in the mouse model of systemic disease.

Wallrodt I, Jelsbak L, Thorndahl L, Thomsen LE, Lemire S, Olsen JE.

PLoS One. 2013 Aug 5;8(8):e70829. doi: 10.1371/journal.pone.0070829. Print 2013.

45.

Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts.

Damkiær S, Yang L, Molin S, Jelsbak L.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7766-71. doi: 10.1073/pnas.1221466110. Epub 2013 Apr 22.

46.

Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison).

Salomonsen CM, Themudo GE, Jelsbak L, Molin S, Høiby N, Hammer AS.

Vet Microbiol. 2013 Apr 12;163(1-2):103-9. doi: 10.1016/j.vetmic.2012.12.003. Epub 2012 Dec 11.

PMID:
23273415
47.

Trapping and proteomic identification of cellular substrates of the ClpP protease in Staphylococcus aureus.

Feng J, Michalik S, Varming AN, Andersen JH, Albrecht D, Jelsbak L, Krieger S, Ohlsen K, Hecker M, Gerth U, Ingmer H, Frees D.

J Proteome Res. 2013 Feb 1;12(2):547-58. doi: 10.1021/pr300394r. Epub 2013 Jan 8.

PMID:
23253041
48.

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.

Folkesson A, Jelsbak L, Yang L, Johansen HK, Ciofu O, Høiby N, Molin S.

Nat Rev Microbiol. 2012 Dec;10(12):841-51. doi: 10.1038/nrmicro2907. Epub 2012 Nov 13. Review.

PMID:
23147702
49.

Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment.

Rau MH, Marvig RL, Ehrlich GD, Molin S, Jelsbak L.

Environ Microbiol. 2012 Aug;14(8):2200-11. doi: 10.1111/j.1462-2920.2012.02795.x. Epub 2012 Jun 5.

PMID:
22672046
50.

Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa.

Marvig RL, Søndergaard MS, Damkiær S, Høiby N, Johansen HK, Molin S, Jelsbak L.

Antimicrob Agents Chemother. 2012 Aug;56(8):4519-21. doi: 10.1128/AAC.00630-12. Epub 2012 May 29.

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