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Items: 1 to 50 of 489

1.

Gestational high fat diet protects 3xTg offspring from memory impairments, synaptic dysfunction, and brain pathology.

Di Meco A, Jelinek J, Lauretti E, Curtis ME, Issa JJ, Praticό D.

Mol Psychiatry. 2019 Aug 27. doi: 10.1038/s41380-019-0489-y. [Epub ahead of print]

PMID:
31451749
2.

Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia.

Chung W, Kelly AD, Kropf P, Fung H, Jelinek J, Su XY, Roboz GJ, Kantarjian HM, Azab M, Issa JJ.

Clin Epigenetics. 2019 Jul 22;11(1):106. doi: 10.1186/s13148-019-0704-3.

3.

rPredictorDB: a predictive database of individual secondary structures of RNAs and their formatted plots.

Jelínek J, Hoksza D, Hajič J, Pešek J, Drozen J, Hladík T, Klimpera M, Vohradský J, Pánek J.

Database (Oxford). 2019 Jan 1;2019. pii: baz047. doi: 10.1093/database/baz047.

4.

Thymine DNA glycosylase as a novel target for melanoma.

Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, Testa JR, Davidson G, Davidson I, Larue L, Sobol RW, Yen TJ, Bellacosa A.

Oncogene. 2019 May;38(19):3710-3728. doi: 10.1038/s41388-018-0640-2. Epub 2019 Jan 23.

5.

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.

Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, Bhanu NV, Simithy J, Patel B, Huang J, Raynal NJ, Garcia BA, Jacobson MA, Kadoch C, Merali S, Zhang Y, Childers W, Abou-Gharbia M, Karanicolas J, Baylin SB, Zahnow CA, Jelinek J, Graña X, Issa JJ.

Cell. 2018 Nov 15;175(5):1244-1258.e26. doi: 10.1016/j.cell.2018.09.051. Epub 2018 Oct 25.

PMID:
30454645
6.

cpPredictor: a web server for template-based prediction of RNA secondary structure.

Jelínek J, Pánek J.

Bioinformatics. 2019 Apr 1;35(7):1231-1233. doi: 10.1093/bioinformatics/bty753.

PMID:
30169571
7.

TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer.

Good CR, Panjarian S, Kelly AD, Madzo J, Patel B, Jelinek J, Issa JJ.

Cancer Res. 2018 Aug 1;78(15):4126-4137. doi: 10.1158/0008-5472.CAN-17-2082. Epub 2018 Jun 11.

8.

Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion.

Garriga J, Laumet G, Chen SR, Zhang Y, Madzo J, Issa JJ, Pan HL, Jelinek J.

J Neurosci. 2018 Jul 4;38(27):6090-6101. doi: 10.1523/JNEUROSCI.2616-17.2018. Epub 2018 Jun 6.

9.

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.

Maifrede S, Nieborowska-Skorska M, Sullivan-Reed K, Dasgupta Y, Podszywalow-Bartnicka P, Le BV, Solecka M, Lian Z, Belyaeva EA, Nersesyan A, Machnicki MM, Toma M, Chatain N, Rydzanicz M, Zhao H, Jelinek J, Piwocka K, Sliwinski T, Stoklosa T, Ploski R, Fischer T, Sykes SM, Koschmieder S, Bullinger L, Valent P, Wasik MA, Huang J, Skorski T.

Blood. 2018 Jul 5;132(1):67-77. doi: 10.1182/blood-2018-02-834895. Epub 2018 May 21.

10.

Demethylator phenotypes in acute myeloid leukemia.

Kelly AD, Madzo J, Madireddi P, Kropf P, Good CR, Jelinek J, Issa JJ.

Leukemia. 2018 Oct;32(10):2178-2188. doi: 10.1038/s41375-018-0084-2. Epub 2018 Mar 7.

11.

Dynamic changes in DNA methylation patterns in canine lymphoma cell lines demonstrated by genome-wide quantitative DNA methylation analysis.

Yamazaki J, Jelinek J, Hisamoto S, Tsukamoto A, Inaba M.

Vet J. 2018 Jan;231:48-54. doi: 10.1016/j.tvjl.2017.11.007. Epub 2017 Nov 22.

PMID:
29429487
12.

Gouty involvement of the patella and extensor mechanism of the knee mimicking aggressive neoplasm. A case series.

Kester C, Wallace MT, Jelinek J, Aboulafia A.

Skeletal Radiol. 2018 Jun;47(6):865-869. doi: 10.1007/s00256-017-2871-7. Epub 2018 Jan 14.

PMID:
29332201
13.

Utilizing knowledge base of amino acids structural neighborhoods to predict protein-protein interaction sites.

Jelínek J, Škoda P, Hoksza D.

BMC Bioinformatics. 2017 Dec 6;18(Suppl 15):492. doi: 10.1186/s12859-017-1921-4.

14.

Digital Restriction Enzyme Analysis of Methylation (DREAM).

Jelinek J, Lee JT, Cesaroni M, Madzo J, Liang S, Lu Y, Issa JJ.

Methods Mol Biol. 2018;1708:247-265. doi: 10.1007/978-1-4939-7481-8_13.

PMID:
29224148
15.

Caloric restriction delays age-related methylation drift.

Maegawa S, Lu Y, Tahara T, Lee JT, Madzo J, Liang S, Jelinek J, Colman RJ, Issa JJ.

Nat Commun. 2017 Sep 14;8(1):539. doi: 10.1038/s41467-017-00607-3.

16.

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells.

Werner RJ, Schultz BM, Huhn JM, Jelinek J, Madzo J, Engel N.

Biol Sex Differ. 2017 Aug 17;8(1):28. doi: 10.1186/s13293-017-0150-x.

17.

Concerning CT features used to select patients for treatment of peritoneal metastases, a pictoral essay.

Sugarbaker PH, Sardi A, Brown G, Dromain C, Rousset P, Jelinek JS.

Int J Hyperthermia. 2017 Aug;33(5):497-504. doi: 10.1080/02656736.2017.1317368.

PMID:
28540832
18.

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer.

Good CR, Madzo J, Patel B, Maegawa S, Engel N, Jelinek J, Issa JJ.

Nucleic Acids Res. 2017 Aug 21;45(14):8269-8281. doi: 10.1093/nar/gkx435.

19.

New species and records of pollen and sap beetles for Iran (Coleoptera: Kateretidae, Nitidulidae).

Audisio P, Cline AR, Lasoń A, Jelínek J, Sabatelli S, Serri S.

Zootaxa. 2017 Jan 9;4216(4):zootaxa.4216.4.5. doi: 10.11646/zootaxa.4216.4.5.

PMID:
28183115
20.

A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.

Kelly AD, Kroeger H, Yamazaki J, Taby R, Neumann F, Yu S, Lee JT, Patel B, Li Y, He R, Liang S, Lu Y, Cesaroni M, Pierce SA, Kornblau SM, Bueso-Ramos CE, Ravandi F, Kantarjian HM, Jelinek J, Issa JP.

Leukemia. 2017 Oct;31(10):2011-2019. doi: 10.1038/leu.2017.12. Epub 2017 Jan 11.

21.

Transcriptional Selectivity of Epigenetic Therapy in Cancer.

Sato T, Cesaroni M, Chung W, Panjarian S, Tran A, Madzo J, Okamoto Y, Zhang H, Chen X, Jelinek J, Issa JJ.

Cancer Res. 2017 Jan 15;77(2):470-481. doi: 10.1158/0008-5472.CAN-16-0834. Epub 2016 Nov 22.

22.

Quadriparesis Caused by Lead Poisoning Nine Years After a Gunshot Wound With Retained Bullet Fragments: A Case Report.

Nally E, Jelinek J, Bunning RD.

PM R. 2017 Apr;9(4):411-414. doi: 10.1016/j.pmrj.2016.09.012. Epub 2016 Oct 6.

PMID:
27721003
23.

DREAM: A Simple Method for DNA Methylation Profiling by High-throughput Sequencing.

Jelinek J, Madzo J.

Methods Mol Biol. 2016;1465:111-27. doi: 10.1007/978-1-4939-4011-0_10.

PMID:
27581143
24.

Four new species of Meligethes Stephens from China and additional data on other species of the genus (Coleoptera: Nitidulidae: Meligethinae).

Liu M, Yang X, Huang M, Jelínek J, Audisio P.

Zootaxa. 2016 Jun 8;4121(2):101-16. doi: 10.11646/zootaxa.4121.2.1.

PMID:
27395211
25.

DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas.

Malouf GG, Su X, Zhang J, Creighton CJ, Ho TH, Lu Y, Raynal NJ, Karam JA, Tamboli P, Allanick F, Mouawad R, Spano JP, Khayat D, Wood CG, Jelinek J, Tannir NM.

Clin Cancer Res. 2016 Dec 15;22(24):6236-6246. Epub 2016 Jun 2.

26.

Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas.

Kleb B, Estécio MR, Zhang J, Tzelepi V, Chung W, Jelinek J, Navone NM, Tahir S, Marquez VE, Issa JP, Maity S, Aparicio A.

Epigenetics. 2016 Mar 3;11(3):184-93. doi: 10.1080/15592294.2016.1146851. Epub 2016 Feb 18.

27.

Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.

Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP.

Cancer Res. 2016 Mar 15;76(6):1494-505. doi: 10.1158/0008-5472.CAN-14-2391. Epub 2015 Dec 30.

28.

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

Bouwmeester MC, Ruiter S, Lommelaars T, Sippel J, Hodemaekers HM, van den Brandhof EJ, Pennings JL, Kamstra JH, Jelinek J, Issa JP, Legler J, van der Ven LT.

Toxicol Appl Pharmacol. 2016 Jan 15;291:84-96. doi: 10.1016/j.taap.2015.12.012. Epub 2015 Dec 19.

PMID:
26712470
29.

Phase 2 clinical trial of sunitinib as adjunctive treatment in patients with advanced differentiated thyroid cancer.

Bikas A, Kundra P, Desale S, Mete M, O'Keefe K, Clark BG, Wray L, Gandhi R, Barett C, Jelinek JS, Wexler JA, Wartofsky L, Burman KD.

Eur J Endocrinol. 2016 Mar;174(3):373-80. doi: 10.1530/EJE-15-0930. Epub 2015 Dec 15.

PMID:
26671977
30.

Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia.

Yamazaki J, Taby R, Jelinek J, Raynal NJ, Cesaroni M, Pierce SA, Kornblau SM, Bueso-Ramos CE, Ravandi F, Kantarjian HM, Issa JP.

J Natl Cancer Inst. 2015 Nov 13;108(2). pii: djv323. doi: 10.1093/jnci/djv323.

31.

G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.

Laumet G, Garriga J, Chen SR, Zhang Y, Li DP, Smith TM, Dong Y, Jelinek J, Cesaroni M, Issa JP, Pan HL.

Nat Neurosci. 2015 Dec;18(12):1746-55. doi: 10.1038/nn.4165. Epub 2015 Nov 9.

32.

Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells.

Jin C, Qin T, Barton MC, Jelinek J, Issa JP.

Epigenetics. 2015;10(11):1006-13. doi: 10.1080/15592294.2015.1091145.

33.

Decreased efficacy of drugs targeting the vascular endothelial growth factor pathway by the epigenetic silencing of FLT1 in renal cancer cells.

Kim JY, Hwang J, Lee SH, Lee HJ, Jelinek J, Jeong H, Lim JS, Kim JM, Song KS, Kim BH, Lee S, Kim J.

Clin Epigenetics. 2015 Sep 16;7:99. doi: 10.1186/s13148-015-0134-9. eCollection 2015.

34.

Epigenetic synergy between decitabine and platinum derivatives.

Qin T, Si J, Raynal NJ, Wang X, Gharibyan V, Ahmed S, Hu X, Jin C, Lu Y, Shu J, Estecio MR, Jelinek J, Issa JJ.

Clin Epigenetics. 2015 Sep 11;7:97. doi: 10.1186/s13148-015-0131-z. eCollection 2015.

35.

New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development.

Foy JP, Pickering CR, Papadimitrakopoulou VA, Jelinek J, Lin SH, William WN Jr, Frederick MJ, Wang J, Lang W, Feng L, Zhang L, Kim ES, Fan YH, Hong WK, El-Naggar AK, Lee JJ, Myers JN, Issa JP, Lippman SM, Mao L, Saintigny P.

Cancer Prev Res (Phila). 2015 Nov;8(11):1027-35. doi: 10.1158/1940-6207.CAPR-14-0179. Epub 2015 Sep 4.

36.

Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features.

Malouf GG, Tahara T, Paradis V, Fabre M, Guettier C, Yamazaki J, Long H, Lu Y, Raynal NJ, Jelinek J, Mouawad R, Khayat D, Brugières L, Raymond E, Issa JP.

Epigenetics. 2015;10(9):872-81. doi: 10.1080/15592294.2015.1076955.

37.

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

Yamazaki J, Jelinek J, Lu Y, Cesaroni M, Madzo J, Neumann F, He R, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Kantarjian HM, Liang S, Estecio MR, Godley LA, Issa JP.

Cancer Res. 2015 Jul 15;75(14):2833-43. doi: 10.1158/0008-5472.CAN-14-0739. Epub 2015 May 13.

38.

Fauna Europaea: Coleoptera 2 (excl. series Elateriformia, Scarabaeiformia, Staphyliniformia and superfamily Curculionoidea).

Audisio P, Alonso Zarazaga MA, Slipinski A, Nilsson A, Jelínek J, Taglianti AV, Turco F, Otero C, Canepari C, Kral D, Liberti G, Sama G, Nardi G, Löbl I, Horak J, Kolibac J, Háva J, Sapiejewski M, Jäch M, Bologna MA, Biondi M, Nikitsky NB, Mazzoldi P, Zahradnik P, Wegrzynowicz P, Constantin R, Gerstmeier R, Zhantiev R, Fattorini S, Tomaszewska W, Rücker WH, Vazquez-Albalate X, Cassola F, Angelini F, Johnson C, Schawaller W, Regalin R, Baviera C, Rocchi S, Cianferoni F, Beenen R, Schmitt M, Sassi D, Kippenberg H, Zampetti MF, Trizzino M, Chiari S, Carpaneto GM, Sabatelli S, de Jong Y.

Biodivers Data J. 2015 Apr 9;(3):e4750. doi: 10.3897/BDJ.3.e4750. eCollection 2015.

39.

Three-dimensional analysis versus goniometric measurement of total active elevation in normal subjects.

Finley M, Jelinek JA, Misamore G.

J Shoulder Elbow Surg. 2015 Sep;24(9):1391-6. doi: 10.1016/j.jse.2015.02.005. Epub 2015 Mar 29.

PMID:
25825139
40.

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy.

Tsimberidou AM, Said R, Culotta K, Wistuba I, Jelinek J, Fu S, Falchook G, Naing A, Piha-Paul S, Zinner R, Siddik ZH, He G, Hess K, Stewart DJ, Kurzrock R, Issa JP.

Clin Epigenetics. 2015 Mar 17;7:29. doi: 10.1186/s13148-015-0065-5. eCollection 2015.

41.

Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A.

van Esterik JC, Vitins AP, Hodemaekers HM, Kamstra JH, Legler J, Pennings JL, Steegenga WT, Lute C, Jelinek J, Issa JP, Dollé ME, van der Ven LT.

Toxicol Lett. 2015 Jan 5;232(1):293-300. doi: 10.1016/j.toxlet.2014.10.021. Epub 2014 Oct 17.

PMID:
25455458
42.

Targeting pleiotropic signaling pathways to control adult cardiac stem cell fate and function.

Pagliari S, Jelinek J, Grassi G, Forte G.

Front Physiol. 2014 Jul 1;5:219. doi: 10.3389/fphys.2014.00219. eCollection 2014. Review.

43.

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples.

Stewart DJ, Nunez MI, Jelinek J, Hong D, Gupta S, Aldaz M, Issa JP, Kurzrock R, Wistuba II.

Clin Epigenetics. 2014 Jul 3;6(1):13. doi: 10.1186/1868-7083-6-13. eCollection 2014.

44.

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.

Jin C, Lu Y, Jelinek J, Liang S, Estecio MR, Barton MC, Issa JP.

Nucleic Acids Res. 2014 Jun;42(11):6956-71. doi: 10.1093/nar/gku372. Epub 2014 May 29.

45.

A phase I study of decitabine with pegylated interferon α-2b in advanced melanoma: impact on DNA methylation and lymphocyte populations.

Plimack ER, Desai JR, Issa JP, Jelinek J, Sharma P, Vence LM, Bassett RL, Ilagan JL, Papadopoulos NE, Hwu WJ.

Invest New Drugs. 2014 Oct;32(5):969-75. doi: 10.1007/s10637-014-0115-4. Epub 2014 May 31.

46.

Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer.

Pathiraja TN, Nayak SR, Xi Y, Jiang S, Garee JP, Edwards DP, Lee AV, Chen J, Shea MJ, Santen RJ, Gannon F, Kangaspeska S, Jelinek J, Issa JP, Richer JK, Elias A, McIlroy M, Young LS, Davidson NE, Schiff R, Li W, Oesterreich S.

Sci Transl Med. 2014 Mar 26;6(229):229ra41. doi: 10.1126/scitranslmed.3008326.

47.

Hospital-admitting privileges in IR.

Jelinek J, Khan A.

J Vasc Interv Radiol. 2014 Mar;25(3):493. doi: 10.1016/j.jvir.2013.11.041. No abstract available.

PMID:
24581477
48.

Age-related epigenetic drift in the pathogenesis of MDS and AML.

Maegawa S, Gough SM, Watanabe-Okochi N, Lu Y, Zhang N, Castoro RJ, Estecio MR, Jelinek J, Liang S, Kitamura T, Aplan PD, Issa JP.

Genome Res. 2014 Apr;24(4):580-91. doi: 10.1101/gr.157529.113. Epub 2014 Jan 10.

49.

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors.

Stewart DJ, Nunez MI, Jelinek J, Hong D, Gupta S, Issa JP, Wistuba II, Kurzrock R.

Clin Epigenetics. 2014 Jan 9;6(1):2. doi: 10.1186/1868-7083-6-2.

50.

Fusobacterium in colonic flora and molecular features of colorectal carcinoma.

Tahara T, Yamamoto E, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T, An B, Shureiqi I, Toyota M, Kondo Y, Estécio MR, Issa JP.

Cancer Res. 2014 Mar 1;74(5):1311-8. doi: 10.1158/0008-5472.CAN-13-1865. Epub 2014 Jan 2.

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