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Items: 1 to 50 of 147

1.

Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies.

Mackenzie GA, Hill PC, Sahito SM, Jeffries DJ, Hossain I, Bottomley C, Uchendu U, Ameh D, Ndiaye M, Osuorah CD, Adeyemi O, Pathirana J, Olatunji Y, Abatan B, Ahameefula E, Muhammad BS, Fombah AE, Saha D, Mackenzie R, Plumb I, Akano A, Ebruke B, Ideh RC, Kuti B, Githua P, Olutunde E, Ofordile O, Green E, Usuf E, Badji H, Ikumapayi UNA, Manjang A, Salaudeen R, Nsekpong ED, Jarju S, Antonio M, Sambou S, Ceesay L, Lowe-Jallow Y, Sowe D, Jasseh M, Mulholland K, Knoll M, Levine OS, Howie SR, Adegbola RA, Greenwood BM, Corrah T.

Lancet Infect Dis. 2017 Sep;17(9):965-973. doi: 10.1016/S1473-3099(17)30321-3. Epub 2017 Jun 7. Erratum in: Lancet Infect Dis. 2018 Jul;18(7):715.

2.

Safety and immunogenicity of inactivated poliovirus vaccine when given with measles-rubella combined vaccine and yellow fever vaccine and when given via different administration routes: a phase 4, randomised, non-inferiority trial in The Gambia.

Clarke E, Saidu Y, Adetifa JU, Adigweme I, Hydara MB, Bashorun AO, Moneke-Anyanwoke N, Umesi A, Roberts E, Cham PM, Okoye ME, Brown KE, Niedrig M, Chowdhury PR, Clemens R, Bandyopadhyay AS, Mueller J, Jeffries DJ, Kampmann B.

Lancet Glob Health. 2016 Aug;4(8):e534-47. doi: 10.1016/S2214-109X(16)30075-4. Epub 2016 Jun 27.

3.

Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study.

Mackenzie GA, Hill PC, Jeffries DJ, Hossain I, Uchendu U, Ameh D, Ndiaye M, Adeyemi O, Pathirana J, Olatunji Y, Abatan B, Muhammad BS, Fombah AE, Saha D, Plumb I, Akano A, Ebruke B, Ideh RC, Kuti B, Githua P, Olutunde E, Ofordile O, Green E, Usuf E, Badji H, Ikumapayi UNA, Manjang A, Salaudeen R, Nsekpong ED, Jarju S, Antonio M, Sambou S, Ceesay L, Lowe-Jallow Y, Jasseh M, Mulholland K, Knoll M, Levine OS, Howie SR, Adegbola RA, Greenwood BM, Corrah T.

Lancet Infect Dis. 2016 Jun;16(6):703-711. doi: 10.1016/S1473-3099(16)00054-2. Epub 2016 Feb 18.

4.

Interferon-γ ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial.

Adetifa IM, Ota MO, Jeffries DJ, Lugos MD, Hammond AS, Battersby NJ, Owiafe PK, Donkor SD, Antonio M, Ibanga HB, Brookes RH, Aka P, Walton R, Adegbola RA, Hill PC.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):439-45. doi: 10.1164/rccm.201208-1352OC. Epub 2012 Dec 6.

PMID:
23220919
5.

Decay kinetics of an interferon gamma release assay with anti-tuberculosis therapy in newly diagnosed tuberculosis cases.

Adetifa IM, Ota MO, Walther B, Hammond AS, Lugos MD, Jeffries DJ, Donkor SA, Adegbola RA, Hill PC.

PLoS One. 2010 Sep 1;5(9). pii: e12502. doi: 10.1371/journal.pone.0012502.

6.

Production of TNF-alpha, IL-12(p40) and IL-17 can discriminate between active TB disease and latent infection in a West African cohort.

Sutherland JS, de Jong BC, Jeffries DJ, Adetifa IM, Ota MO.

PLoS One. 2010 Aug 24;5(8):e12365. doi: 10.1371/journal.pone.0012365.

7.

Commercial interferon gamma release assays compared to the tuberculin skin test for diagnosis of latent Mycobacterium tuberculosis infection in childhood contacts in the Gambia.

Adetifa IM, Ota MO, Jeffries DJ, Hammond A, Lugos MD, Donkor S, Patrick O, Adegbola RA, Hill PC.

Pediatr Infect Dis J. 2010 May;29(5):439-43. doi: 10.1097/INF.0b013e3181cb45da.

PMID:
20068506
8.

High granulocyte/lymphocyte ratio and paucity of NKT cells defines TB disease in a TB-endemic setting.

Sutherland JS, Jeffries DJ, Donkor S, Walther B, Hill PC, Adetifa IM, Adegbola RA, Ota MO.

Tuberculosis (Edinb). 2009 Nov;89(6):398-404. doi: 10.1016/j.tube.2009.07.004. Epub 2009 Aug 14.

PMID:
19683473
9.

Supervised learning for the automated transcription of spacer classification from spoligotype films.

Jeffries DJ, Abernethy N, de Jong BC.

BMC Bioinformatics. 2009 Aug 12;10:248. doi: 10.1186/1471-2105-10-248.

10.

Access to health care and mortality of children under 5 years of age in the Gambia: a case-control study.

Rutherford ME, Dockerty JD, Jasseh M, Howie SR, Herbison P, Jeffries DJ, Leach M, Stevens W, Mulholland K, Adegbola RA, Hill PC.

Bull World Health Organ. 2009 Mar;87(3):216-24.

11.

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

Rutherford ME, Dockerty JD, Jasseh M, Howie SR, Herbison P, Jeffries DJ, Mulholland K, Adegbola RA, Hill PC.

Trop Med Int Health. 2009 Feb;14(2):149-55. doi: 10.1111/j.1365-3156.2008.02204.x. Epub 2009 Jan 20.

12.

Quality and outcomes framework. QOF as Trojan horse.

Jeffries DJ.

BMJ. 2009 Jan 21;338:b191. doi: 10.1136/bmj.b191. No abstract available.

PMID:
19158169
13.

Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa.

Brookes RH, Hill PC, Owiafe PK, Ibanga HB, Jeffries DJ, Donkor SA, Fletcher HA, Hammond AS, Lienhardt C, Adegbola RA, McShane H, Hill AV.

PLoS One. 2008 Aug 13;3(8):e2921. doi: 10.1371/journal.pone.0002921. Erratum in: PLoS One. 2011;6(2). doi:10.1371/annotation/5284a0b6-62a9-484e-80a4-a08c59b3b17c.

14.

Haematological values from a Gambian cohort--possible reference range for a West African population.

Adetifa IM, Hill PC, Jeffries DJ, Jackson-Sillah D, Ibanga HB, Bah G, Donkor S, Corrah T, Adegbola RA.

Int J Lab Hematol. 2009 Dec;31(6):615-22. doi: 10.1111/j.1751-553X.2008.01087.x. Epub 2008 Jul 10.

PMID:
18631172
15.

Longitudinal assessment of an ELISPOT test for Mycobacterium tuberculosis infection.

Hill PC, Brookes RH, Fox A, Jackson-Sillah D, Jeffries DJ, Lugos MD, Donkor SA, Adetifa IM, de Jong BC, Aiken AM, Adegbola RA, McAdam KP.

PLoS Med. 2007 Jun;4(6):e192.

16.

Risk factors for and clinical outcome of congenital cytomegalovirus infection in a peri-urban West-African birth cohort.

van der Sande MA, Kaye S, Miles DJ, Waight P, Jeffries DJ, Ojuola OO, Palmero M, Pinder M, Ismaili J, Flanagan KL, Aveika AA, Zaman A, Rowland-Jones S, McConkey SJ, Whittle HC, Marchant A.

PLoS One. 2007 Jun 6;2(6):e492.

17.

FOXP3 gene expression in a tuberculosis case contact study.

Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH.

Clin Exp Immunol. 2007 Jul;149(1):117-22. Epub 2007 Apr 26.

18.

ESAT-6 and CFP-10 can be combined to reduce the cost of testing for Mycobacterium tuberculosis infection, but CFP-10 responses associate with active disease.

Fox A, Jeffries DJ, Hill PC, Hammond AS, Lugos MD, Jackson-Sillah D, Donkor SA, Owiafe PK, McAdam KP, Brookes RH.

Trans R Soc Trop Med Hyg. 2007 Jul;101(7):691-8. Epub 2007 Apr 16.

PMID:
17434194
19.

Clinical presentation and outcome of tuberculosis patients infected by M. africanum versus M. tuberculosis.

de Jong BC, Hill PC, Aiken A, Jeffries DJ, Onipede A, Small PM, Adegbola RA, Corrah TP.

Int J Tuberc Lung Dis. 2007 Apr;11(4):450-6.

PMID:
17394693
20.

Using ELISPOT to expose false positive skin test conversion in tuberculosis contacts.

Hill PC, Jeffries DJ, Brookes RH, Fox A, Jackson-Sillah D, Lugos MD, Donkor SA, de Jong BC, Corrah T, Adegbola RA, McAdam KP.

PLoS One. 2007 Jan 31;2(1):e183.

21.

Surprisingly high specificity of the PPD skin test for M. tuberculosis infection from recent exposure in The Gambia.

Hill PC, Brookes RH, Fox A, Jackson-Sillah D, Lugos MD, Jeffries DJ, Donkor SA, Adegbola RA, McAdam KP.

PLoS One. 2006 Dec 20;1:e68.

22.

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.

Duvall MG, Jaye A, Dong T, Brenchley JM, Alabi AS, Jeffries DJ, van der Sande M, Togun TO, McConkey SJ, Douek DC, McMichael AJ, Whittle HC, Koup RA, Rowland-Jones SL.

J Immunol. 2006 Jun 1;176(11):6973-81.

23.

Comparison of enzyme-linked immunospot assay and tuberculin skin test in healthy children exposed to Mycobacterium tuberculosis.

Hill PC, Brookes RH, Adetifa IM, Fox A, Jackson-Sillah D, Lugos MD, Donkor SA, Marshall RJ, Howie SR, Corrah T, Jeffries DJ, Adegbola RA, McAdam KP.

Pediatrics. 2006 May;117(5):1542-8.

PMID:
16651307
24.

Mycobacterium africanum elicits an attenuated T cell response to early secreted antigenic target, 6 kDa, in patients with tuberculosis and their household contacts.

de Jong BC, Hill PC, Brookes RH, Gagneux S, Jeffries DJ, Otu JK, Donkor SA, Fox A, McAdam KP, Small PM, Adegbola RA.

J Infect Dis. 2006 May 1;193(9):1279-86. Epub 2006 Mar 31.

PMID:
16586366
25.

Identifying ELISPOT and skin test cut-offs for diagnosis of Mycobacterium tuberculosis infection in The Gambia.

Jeffries DJ, Hill PC, Fox A, Lugos M, Jackson-Sillah DJ, Adegbola RA, Brookes RH.

Int J Tuberc Lung Dis. 2006 Feb;10(2):192-8.

PMID:
16499260
26.

ESAT-6/CFP-10 fusion protein and peptides for optimal diagnosis of mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia.

Hill PC, Jackson-Sillah D, Fox A, Franken KL, Lugos MD, Jeffries DJ, Donkor SA, Hammond AS, Adegbola RA, Ottenhoff TH, Klein MR, Brookes RH.

J Clin Microbiol. 2005 May;43(5):2070-4.

27.

Quantitative T cell assay reflects infectious load of Mycobacterium tuberculosis in an endemic case contact model.

Hill PC, Fox A, Jeffries DJ, Jackson-Sillah D, Lugos MD, Owiafe PK, Donkor SA, Hammond AS, Corrah T, Adegbola RA, McAdam KP, Brookes RH.

Clin Infect Dis. 2005 Jan 15;40(2):273-8. Epub 2004 Dec 20.

PMID:
15655747
28.

Design and implementation of relational databases relevant to the diverse needs of a tuberculosis case contact study in the Gambia.

Jeffries DJ, Donkor S, Brookes RH, Fox A, Hill PC.

Int J Tuberc Lung Dis. 2004 Sep;8(9):1095-9.

PMID:
15455594
29.
30.

Large-scale evaluation of enzyme-linked immunospot assay and skin test for diagnosis of Mycobacterium tuberculosis infection against a gradient of exposure in The Gambia.

Hill PC, Brookes RH, Fox A, Fielding K, Jeffries DJ, Jackson-Sillah D, Lugos MD, Owiafe PK, Donkor SA, Hammond AS, Otu JK, Corrah T, Adegbola RA, McAdam KP.

Clin Infect Dis. 2004 Apr 1;38(7):966-73. Epub 2004 Mar 16.

PMID:
15034828
31.

Herpes simplex virus type 1 infection associated with atrial myxoma.

Li Y, Pan Z, Ji Y, Sheppard M, Jeffries DJ, Archard LC, Zhang H.

Am J Pathol. 2003 Dec;163(6):2407-12.

32.

Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease.

Seemungal T, Harper-Owen R, Bhowmik A, Moric I, Sanderson G, Message S, Maccallum P, Meade TW, Jeffries DJ, Johnston SL, Wedzicha JA.

Am J Respir Crit Care Med. 2001 Nov 1;164(9):1618-23.

PMID:
11719299
33.

Nosocomial spread of viral disease.

Aitken C, Jeffries DJ.

Clin Microbiol Rev. 2001 Jul;14(3):528-46. Review.

34.

Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease.

Roland M, Bhowmik A, Sapsford RJ, Seemungal TA, Jeffries DJ, Warner TD, Wedzicha JA.

Thorax. 2001 Jan;56(1):30-5.

35.

Detection of rhinovirus in induced sputum at exacerbation of chronic obstructive pulmonary disease.

Seemungal TA, Harper-Owen R, Bhowmik A, Jeffries DJ, Wedzicha JA.

Eur Respir J. 2000 Oct;16(4):677-83.

36.

Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels.

Wedzicha JA, Seemungal TA, MacCallum PK, Paul EA, Donaldson GC, Bhowmik A, Jeffries DJ, Meade TW.

Thromb Haemost. 2000 Aug;84(2):210-5.

PMID:
10959691
37.

Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease.

Seemungal TA, Donaldson GC, Bhowmik A, Jeffries DJ, Wedzicha JA.

Am J Respir Crit Care Med. 2000 May;161(5):1608-13.

PMID:
10806163
38.

Needlestick injury in clothing industry workers and the risks of blood-borne infection.

Ind JE, Jeffries DJ.

Occup Med (Lond). 1999 Jan;49(1):47-9.

PMID:
10451587
39.
40.

Effect of temperature on lung function and symptoms in chronic obstructive pulmonary disease.

Donaldson GC, Seemungal T, Jeffries DJ, Wedzicha JA.

Eur Respir J. 1999 Apr;13(4):844-9.

41.

Molecular biology of varicella-zoster virus. A review prepared for the UK Advisory Group on Chickenpox.

Harper DR, Gilbert RL, Jeffries DJ.

J Infect. 1998 Jan;36 Suppl 1:1-10. Review.

PMID:
9514102
42.

Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease.

Seemungal TA, Donaldson GC, Paul EA, Bestall JC, Jeffries DJ, Wedzicha JA.

Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1418-22.

PMID:
9603117
43.

Cloning, expression, and immunogenicity of the assembly protein of varicella-zoster virus and detection of the products of open reading frame 33.

Garcia-Valcarcel M, Fowler WJ, Harper DR, Jeffries DJ, Layton GT.

J Med Virol. 1997 Dec;53(4):332-9.

PMID:
9407380
44.

DNA viruses in the pathogenesis of sporadic chronic idiopathic intestinal pseudo-obstruction.

Debinski HS, Kamm MA, Talbot IC, Khan G, Kangro HO, Jeffries DJ.

Gut. 1997 Jul;41(1):100-6.

45.
46.

HIV antibody testing: Genito-Urinary Clinic or additional site same-day testing service.

Hudson MM, Nelson WL, Ronalds CJ, Anderson J, Jeffries DJ.

AIDS Care. 1997 Apr;9(2):209-15.

PMID:
9135634
47.

Ethnic differences in women with HIV infection in Britain and Ireland. The study group for the mrc collaborative study of HIV infection in women.

Anderson J, Melville R, Jeffries DJ, Norman J, Welch J, Graham D, Fadojutimi M, Forster G, Phillips M, Sampson K, Kitchen V, Wells C, Byrne G, Mercey DE, Allason-Jones E, Campbell L, French R, Woronowski H, Griffioen A, Stephenson JM, Phillips AN, Keenlyside R, Johnson AM, Barton S, Chard S Harindra V, et al.

AIDS. 1996 Jan;10(1):89-93.

PMID:
8924257
48.

Identification of immunodominant regions and linear B cell epitopes of the gE envelope protein of varicella-zoster virus.

Fowler WJ, Garcia-Valcarcel M, Hill-Perkins MS, Murphy G, Harper DR, Jeffries DJ, Burns NR, Adams SE, Kingsman AJ, Layton GT.

Virology. 1995 Dec 20;214(2):531-40.

49.

Risk factors for HIV infection overlooked in routine antenatal care.

Hawken J, Chard T, Costeloe K, Jeffries DJ, Hudson CN.

J R Soc Med. 1995 Nov;88(11):634-6.

50.

The activity of candidate virucidal agents, low pH and genital secretions against HIV-1 in vitro.

O'Connor TJ, Kinchington D, Kangro HO, Jeffries DJ.

Int J STD AIDS. 1995 Jul-Aug;6(4):267-72.

PMID:
7548290

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