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High-Quality Draft Genome Sequence of the Causal Agent of the Current Panama Disease Epidemic.

Warmington RJ, Kay W, Jeffries A, O'Neill P, Farbos A, Moore K, Bebber DP, Studholme DJ.

Microbiol Resour Announc. 2019 Sep 5;8(36). pii: e00904-19. doi: 10.1128/MRA.00904-19.


Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging.

Jeffries AR, Maroofian R, Salter CG, Chioza BA, Cross HE, Patton MA, Dempster E, Temple IK, Mackay DJG, Rezwan FI, Aksglaede L, Baralle D, Dabir T, Hunter MF, Kamath A, Kumar A, Newbury-Ecob R, Selicorni A, Springer A, Van Maldergem L, Varghese V, Yachelevich N, Tatton-Brown K, Mill J, Crosby AH, Baple EL.

Genome Res. 2019 Jul;29(7):1057-1066. doi: 10.1101/gr.243584.118. Epub 2019 Jun 3.


Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.

Jones SE, Lane JM, Wood AR, van Hees VT, Tyrrell J, Beaumont RN, Jeffries AR, Dashti HS, Hillsdon M, Ruth KS, Tuke MA, Yaghootkar H, Sharp SA, Jie Y, Thompson WD, Harrison JW, Dawes A, Byrne EM, Tiemeier H, Allebrandt KV, Bowden J, Ray DW, Freathy RM, Murray A, Mazzotti DR, Gehrman PR, Lawlor DA, Frayling TM, Rutter MK, Hinds DA, Saxena R, Weedon MN.

Nat Commun. 2019 Jan 29;10(1):343. doi: 10.1038/s41467-018-08259-7.


Biallelic SQSTM1 mutations in early-onset, variably progressive neurodegeneration.

Muto V, Flex E, Kupchinsky Z, Primiano G, Galehdari H, Dehghani M, Cecchetti S, Carpentieri G, Rizza T, Mazaheri N, Sedaghat A, Vahidi Mehrjardi MY, Traversa A, Di Nottia M, Kousi MM, Jamshidi Y, Ciolfi A, Caputo V, Malamiri RA, Pantaleoni F, Martinelli S, Jeffries AR, Zeighami J, Sherafat A, Di Giuda D, Shariati GR, Carrozzo R, Katsanis N, Maroofian R, Servidei S, Tartaglia M.

Neurology. 2018 Jul 24;91(4):e319-e330. doi: 10.1212/WNL.0000000000005869. Epub 2018 Jun 29.


Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons.

Mis MA, Rogers MF, Jeffries AR, Wilbrey AL, Chen L, Yang Y, Dib-Hajj S, Waxman SG, Stevens EB, Randall AD.

Aging Cell. 2018 Aug;17(4):e12795. doi: 10.1111/acel.12795. Epub 2018 Jun 25.


BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs.

Ledingham J, Gullick N, Irving K, Gorodkin R, Aris M, Burke J, Gordon P, Christidis D, Galloway S, Hayes E, Jeffries A, Mercer S, Mooney J, van Leuven S, Galloway J.

Rheumatology (Oxford). 2017 Dec 1;56(12):2257. doi: 10.1093/rheumatology/kex389. No abstract available.


Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.

Imm J, Kerrigan TL, Jeffries A, Lunnon K.

Epigenomics. 2017 Nov;9(11):1455-1468. doi: 10.2217/epi-2017-0076. Epub 2017 Oct 3. Review.


Human microglia and astrocytes express cGAS-STING viral sensing components.

Jeffries AM, Marriott I.

Neurosci Lett. 2017 Sep 29;658:53-56. doi: 10.1016/j.neulet.2017.08.039. Epub 2017 Aug 19.


Interplay Of Stereochemistry, Conformational Rigidity, And Ease Of Synthesis For 13-Membered Cyclic Peptidomimetics Containing APC Residues.

Xin D, Jeffries A, Burgess K.

ACS Comb Sci. 2017 Jun 12;19(6):414-421. doi: 10.1021/acscombsci.7b00041. Epub 2017 May 31.


Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue.

Devall M, Smith RG, Jeffries A, Hannon E, Davies MN, Schalkwyk L, Mill J, Weedon M, Lunnon K.

Clin Epigenetics. 2017 May 3;9:47. doi: 10.1186/s13148-017-0337-3. eCollection 2017.


BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs.

Ledingham J, Gullick N, Irving K, Gorodkin R, Aris M, Burke J, Gordon P, Christidis D, Galloway S, Hayes E, Jeffries A, Mercer S, Mooney J, van Leuven S, Galloway J; BSR and BHPR Standards, Guidelines and Audit Working Group.

Rheumatology (Oxford). 2017 Jun 1;56(6):865-868. doi: 10.1093/rheumatology/kew479. No abstract available. Erratum in: Rheumatology (Oxford). 2017 Dec 1;56(12 ):2257.


X-ray fluorescence at nanoscale resolution for multicomponent layered structures: a solar cell case study.

West BM, Stuckelberger M, Jeffries A, Gangam S, Lai B, Stripe B, Maser J, Rose V, Vogt S, Bertoni MI.

J Synchrotron Radiat. 2017 Jan 1;24(Pt 1):288-295. doi: 10.1107/S1600577516015721. Epub 2017 Jan 1.


Profiling Regulatory Variation in the Brain: Methods for Exploring the Neuronal Epigenome.

Jeffries AR, Mill J.

Biol Psychiatry. 2017 Jan 15;81(2):90-91. doi: 10.1016/j.biopsych.2016.10.019. No abstract available.


Quantifying Training Loads in Contemporary Dance.

Jeffries AC, Wallace L, Coutts AJ.

Int J Sports Physiol Perform. 2017 Jul;12(6):796-802. doi: 10.1123/ijspp.2016-0159. Epub 2016 Nov 11.


Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogramming.

Jeffries AR, Uwanogho DA, Cocks G, Perfect LW, Dempster E, Mill J, Price J.

RNA. 2016 Oct;22(10):1620-30. doi: 10.1261/rna.058347.116. Epub 2016 Aug 18.


A comparison of mitochondrial DNA isolation methods in frozen post-mortem human brain tissue--applications for studies of mitochondrial genetics in brain disorders.

Devall M, Burrage J, Caswell R, Johnson M, Troakes C, Al-Sarraj S, Jeffries AR, Mill J, Lunnon K.

Biotechniques. 2015 Oct 1;59(4):241-2, 244-6. doi: 10.2144/000114343. eCollection 2015 Oct.


Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner.

van der Linde S, Romano T, Wadley G, Jeffries AJ, Wlodek ME, Hryciw DH.

J Dev Orig Health Dis. 2014 Aug;5(4):314-21. doi: 10.1017/S2040174414000245.


Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.

Jeffries AR, Collier DA, Vassos E, Curran S, Ogilvie CM, Price J.

PLoS One. 2013 Dec 27;8(12):e85093. doi: 10.1371/journal.pone.0085093. eCollection 2013.


Mapping the primate lateral geniculate nucleus: a review of experiments and methods.

Jeffries AM, Killian NJ, Pezaris JS.

J Physiol Paris. 2014 Feb;108(1):3-10. doi: 10.1016/j.jphysparis.2013.10.001. Epub 2013 Nov 21. Review.


Visual acuity of simulated thalamic visual prostheses in normally sighted humans.

Bourkiza B, Vurro M, Jeffries A, Pezaris JS.

PLoS One. 2013 Sep 27;8(9):e73592. doi: 10.1371/journal.pone.0073592. eCollection 2013.


The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders.

Cocks G, Curran S, Gami P, Uwanogho D, Jeffries AR, Kathuria A, Lucchesi W, Wood V, Dixon R, Ogilvie C, Steckler T, Price J.

Psychopharmacology (Berl). 2014 Mar;231(6):1079-88. doi: 10.1007/s00213-013-3196-4. Epub 2013 Jul 10. Review.


Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons.

Cocks G, Romanyuk N, Amemori T, Jendelova P, Forostyak O, Jeffries AR, Perfect L, Thuret S, Dayanithi G, Sykova E, Price J.

Stem Cell Res Ther. 2013 Jun 7;4(3):69. doi: 10.1186/scrt220.


Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits.

Wong CC, Meaburn EL, Ronald A, Price TS, Jeffries AR, Schalkwyk LC, Plomin R, Mill J.

Mol Psychiatry. 2014 Apr;19(4):495-503. doi: 10.1038/mp.2013.41. Epub 2013 Apr 23.


Stochastic choice of allelic expression in human neural stem cells.

Jeffries AR, Perfect LW, Ledderose J, Schalkwyk LC, Bray NJ, Mill J, Price J.

Stem Cells. 2012 Sep;30(9):1938-47. doi: 10.1002/stem.1155.


Knockdown of the psychosis susceptibility gene ZNF804A alters expression of genes involved in cell adhesion.

Hill MJ, Jeffries AR, Dobson RJ, Price J, Bray NJ.

Hum Mol Genet. 2012 Mar 1;21(5):1018-24. doi: 10.1093/hmg/ddr532. Epub 2011 Nov 11.


Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway.

El-Akabawy G, Medina LM, Jeffries A, Price J, Modo M.

Stem Cells Dev. 2011 Nov;20(11):1873-87. doi: 10.1089/scd.2010.0282. Epub 2011 Apr 5.


Effects of cis-regulatory variation differ across regions of the adult human brain.

Buonocore F, Hill MJ, Campbell CD, Oladimeji PB, Jeffries AR, Troakes C, Hortobagyi T, Williams BP, Cooper JD, Bray NJ.

Hum Mol Genet. 2010 Nov 15;19(22):4490-6. doi: 10.1093/hmg/ddq380. Epub 2010 Sep 9.


Allelic skewing of DNA methylation is widespread across the genome.

Schalkwyk LC, Meaburn EL, Smith R, Dempster EL, Jeffries AR, Davies MN, Plomin R, Mill J.

Am J Hum Genet. 2010 Feb 12;86(2):196-212. doi: 10.1016/j.ajhg.2010.01.014.


The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation.

Sherwood V, Recino A, Jeffries A, Ward A, Chalmers AD.

Biochem J. 2009 Dec 23;425(2):303-11. doi: 10.1042/BJ20091318. Review.


Positional specification in a neural stem cell line involves modulation of Musashi1 expression.

Morgan SC, Yasin S, Uwanogho D, Jeffries A, Price J.

Stem Cells Dev. 2010 Apr;19(4):579-92. doi: 10.1089/scd.2009.0108.


Management. New policies stomp out freebies, industry gifts.

Jeffries A.

Hosp Health Netw. 2008 Jun;82(6):20-1. No abstract available.


Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival.

Lou Y, Basha G, Seipp RP, Cai B, Chen SS, Moise AR, Jeffries AP, Gopaul RS, Vitalis TZ, Jefferies WA.

Clin Cancer Res. 2008 Mar 1;14(5):1494-501. doi: 10.1158/1078-0432.CCR-07-1066.


TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma.

Zhang QJ, Seipp RP, Chen SS, Vitalis TZ, Li XL, Choi KB, Jeffries A, Jefferies WA.

Int J Cancer. 2007 May 1;120(9):1935-41.


Tumour immunity and T cell memory are induced by low dose inoculation with a non-replicating adenovirus encoding TAP1.

Lou Y, Seipp RP, Cai B, Chen SS, Vitalis TZ, Choi KB, Jeffries AP, Gopaul RS, Li XL, Seliger B, Pearson TW, Jefferies WA.

Vaccine. 2007 Mar 8;25(12):2331-9. Epub 2006 Dec 12.


RE1 Silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells.

Greenway DJ, Street M, Jeffries A, Buckley NJ.

Stem Cells. 2007 Feb;25(2):354-63. Epub 2006 Nov 2.


Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease.

Dickstein DL, Biron KE, Ujiie M, Pfeifer CG, Jeffries AR, Jefferies WA.

FASEB J. 2006 Mar;20(3):426-33. Erratum in: FASEB J. 2006 Jul;20(9):1573.


Using the TAP component of the antigen-processing machinery as a molecular adjuvant.

Vitalis TZ, Zhang QJ, Alimonti J, Chen SS, Basha G, Moise A, Tiong J, Tian MM, Choi KB, Waterfield D, Jeffries A, Jefferies WA.

PLoS Pathog. 2005 Dec;1(4):e36. Epub 2005 Dec 30.


Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specific immune responses and survival.

Lou Y, Vitalis TZ, Basha G, Cai B, Chen SS, Choi KB, Jeffries AP, Elliott WM, Atkins D, Seliger B, Jefferies WA.

Cancer Res. 2005 Sep 1;65(17):7926-33.


Molecular and phenotypic characterization of ring chromosome 22.

Jeffries AR, Curran S, Elmslie F, Sharma A, Wenger S, Hummel M, Powell J.

Am J Med Genet A. 2005 Aug 30;137(2):139-47.


beta-1,3-Glucuronyltransferase-1 gene implicated as a candidate for a schizophrenia-like psychosis through molecular analysis of a balanced translocation.

Jeffries AR, Mungall AJ, Dawson E, Halls K, Langford CF, Murray RM, Dunham I, Powell JF.

Mol Psychiatry. 2003 Jul;8(7):654-63.


EU requirement to survey for BSE in fallen stock: consequences for postmortem examination.

Jeffcott LB, Jeffries A, Mueller K.

Vet Rec. 2001 Nov 17;149(20):631. No abstract available.


The complete genome of the crenarchaeon Sulfolobus solfataricus P2.

She Q, Singh RK, Confalonieri F, Zivanovic Y, Allard G, Awayez MJ, Chan-Weiher CC, Clausen IG, Curtis BA, De Moors A, Erauso G, Fletcher C, Gordon PM, Heikamp-de Jong I, Jeffries AC, Kozera CJ, Medina N, Peng X, Thi-Ngoc HP, Redder P, Schenk ME, Theriault C, Tolstrup N, Charlebois RL, Doolittle WF, Duguet M, Gaasterland T, Garrett RA, Ragan MA, Sensen CW, Van der Oost J.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7835-40. Epub 2001 Jun 26.


Genome sequencing and annotation.

Jeffries AC, Saunders NJ, Hood DW.

Methods Mol Med. 2001;67:215-30. doi: 10.1385/1-59259-149-3:215.


Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58.

Saunders NJ, Jeffries AC, Peden JF, Hood DW, Tettelin H, Rappuoli R, Moxon ER.

Mol Microbiol. 2000 Jul;37(1):207-15.


High rates of phase variation in Campylobacter jejuni?

Saunders NJ, Jeffries AC, Hood DW, Moxon ER.

Mol Microbiol. 2000 Jun;36(6):1504. No abstract available.


Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

Pizza M, Scarlato V, Masignani V, Giuliani MM, Aric├▓ B, Comanducci M, Jennings GT, Baldi L, Bartolini E, Capecchi B, Galeotti CL, Luzzi E, Manetti R, Marchetti E, Mora M, Nuti S, Ratti G, Santini L, Savino S, Scarselli M, Storni E, Zuo P, Broeker M, Hundt E, Knapp B, Blair E, Mason T, Tettelin H, Hood DW, Jeffries AC, Saunders NJ, Granoff DM, Venter JC, Moxon ER, Grandi G, Rappuoli R.

Science. 2000 Mar 10;287(5459):1816-20.


Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.

Tettelin H, Saunders NJ, Heidelberg J, Jeffries AC, Nelson KE, Eisen JA, Ketchum KA, Hood DW, Peden JF, Dodson RJ, Nelson WC, Gwinn ML, DeBoy R, Peterson JD, Hickey EK, Haft DH, Salzberg SL, White O, Fleischmann RD, Dougherty BA, Mason T, Ciecko A, Parksey DS, Blair E, Cittone H, Clark EB, Cotton MD, Utterback TR, Khouri H, Qin H, Vamathevan J, Gill J, Scarlato V, Masignani V, Pizza M, Grandi G, Sun L, Smith HO, Fraser CM, Moxon ER, Rappuoli R, Venter JC.

Science. 2000 Mar 10;287(5459):1809-15.

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