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Items: 1 to 50 of 122

1.

PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors.

Payne SN, Maher ME, Tran NH, Van De Hey DR, Foley TM, Yueh AE, Leystra AA, Pasch CA, Jeffrey JJ, Clipson L, Matkowskyj KA, Deming DA.

Oncogenesis. 2015 Oct 5;4:e169. doi: 10.1038/oncsis.2015.28.

2.

Interstitial collagenase activity stimulates the formation of actin rings and ruffled membranes in mouse marrow osteoclasts.

Holliday LS, Welgus HG, Hanna J, Lee BS, Lu M, Jeffrey JJ, Gluck SL.

Calcif Tissue Int. 2003 Mar;72(3):206-14. Epub 2003 Jan 15.

PMID:
12522662
3.
4.

Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation.

Ranganathan AC, Nelson KK, Rodriguez AM, Kim KH, Tower GB, Rutter JL, Brinckerhoff CE, Huang TT, Epstein CJ, Jeffrey JJ, Melendez JA.

J Biol Chem. 2001 Apr 27;276(17):14264-70. Epub 2001 Jan 31.

5.

Localization and regulation of IL-1alpha in rat myometrium during late pregnancy and the postpartum period.

Melendez JA, Vinci JM, Jeffrey JJ, Wilcox BD.

Am J Physiol Regul Integr Comp Physiol. 2001 Mar;280(3):R879-88.

6.

Serotonin-dependent collagenase transcription in myometrial cells requires extended AP-1 site.

Wilcox CB, Weisberg E, Dumin JA, Wilcox BD, Jeffrey JJ.

Mol Cell Endocrinol. 2000 Dec 22;170(1-2):41-56.

PMID:
11162889
7.

Effects of dioxin and estrogen on collagenase-3 in UMR 106-01 osteosarcoma cells.

Partridge NC, Fiacco GJ, Walling HW, Barmina OY, Jeffrey JJ, Ruh MF.

Arch Biochem Biophys. 2000 Oct 15;382(2):182-8.

PMID:
11068867
8.

Progesterone mediates decreases in uterine smooth muscle cell interleukin-1alpha by a mechanism involving decreased stability of IL-1alpha mRNA.

Lan L, Vinci JM, Melendez JA, Jeffrey JJ, Wilcox BD.

Mol Cell Endocrinol. 1999 Sep 10;155(1-2):123-33.

PMID:
10580845
9.

Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts.

Solís-Herruzo JA, Rippe RA, Schrum LW, de La Torre P, García I, Jeffrey JJ, Muñoz-Yagüe T, Brenner DA.

J Biol Chem. 1999 Oct 22;274(43):30919-26.

10.

Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization.

Barmina OY, Walling HW, Fiacco GJ, Freije JM, López-Otín C, Jeffrey JJ, Partridge NC.

J Biol Chem. 1999 Oct 15;274(42):30087-93.

11.
12.

Regulation of the collagenase-3 receptor and its role in intracellular ligand processing in rat osteoblastic cells.

Walling HW, Chan PT, Omura TH, Barmina OY, Fiacco GJ, Jeffrey JJ, Partridge NC.

J Cell Physiol. 1998 Dec;177(4):563-74.

PMID:
10092209
13.

Induction of matrix metalloproteinases and collagenolysis in chick embryonic membranes before hatching.

Lei H, Furth EE, Kalluri R, Wakenell P, Kallen CB, Jeffrey JJ, Leboy PS, Strauss JF 3rd.

Biol Reprod. 1999 Jan;60(1):183-9.

PMID:
9858504
14.

Collagenase and tissue plasminogen activator production in developing rat calvariae: normal progression despite fetal exposure to microgravity.

Davis BA, Sipe B, Gershan LA, Fiacco GJ, Lorenz TC, Jeffrey JJ, Partridge NC.

Calcif Tissue Int. 1998 Nov;63(5):416-22.

PMID:
9799827
15.

Serotonin-mediated production of interstitial collagenase by uterine smooth muscle cells requires interleukin-1alpha, but not interleukin-1beta.

Dumin J, Wilcox BD, Otterness I, Melendez JA, Huang C, Jeffrey JJ.

J Biol Chem. 1998 Sep 25;273(39):25488-94.

16.

Serotonin regulates the expression of the gene for alpha2-macroglobulin in myometrial smooth muscle cells.

Huang C, Jeffrey JJ.

Mol Cell Endocrinol. 1998 Apr 30;139(1-2):79-87.

PMID:
9705076
17.
18.

Initiation of osteoclast bone resorption by interstitial collagenase.

Holliday LS, Welgus HG, Fliszar CJ, Veith GM, Jeffrey JJ, Gluck SL.

J Biol Chem. 1997 Aug 29;272(35):22053-8.

19.

Localization and activation of type IV collagenase/gelatinase at endothelial focal contacts.

Partridge CA, Phillips PG, Niedbala MJ, Jeffrey JJ.

Am J Physiol. 1997 May;272(5 Pt 1):L813-22.

PMID:
9176243
20.
21.

Different collagenase gene products have different roles in degradation of type I collagen.

Krane SM, Byrne MH, Lemaître V, Henriet P, Jeffrey JJ, Witter JP, Liu X, Wu H, Jaenisch R, Eeckhout Y.

J Biol Chem. 1996 Nov 8;271(45):28509-15.

22.

A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor.

Lei H, Furth EE, Kalluri R, Chiou T, Tilly KI, Tilly JL, Elkon KB, Jeffrey JJ, Strauss JF 3rd.

J Clin Invest. 1996 Nov 1;98(9):1971-8.

23.

Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury.

Fini ME, Parks WC, Rinehart WB, Girard MT, Matsubara M, Cook JR, West-Mays JA, Sadow PM, Burgeson RE, Jeffrey JJ, Raizman MB, Krueger RR, Zieske JD.

Am J Pathol. 1996 Oct;149(4):1287-302.

24.

Serotonin regulation of gene expression in uterine extracellular matrix: reciprocal effects on collagens and collagenase.

Passaretti TV, Wilcox BD, Jeffrey JJ.

Mol Cell Endocrinol. 1996 Jul 1;120(2):125-32.

PMID:
8832571
25.

Transcriptional and posttranscriptional regulation of interstitial collagenase by platelet-derived growth factor BB in bone cell cultures.

Varghese S, Delany AM, Liang L, Gabbitas B, Jeffrey JJ, Canalis E.

Endocrinology. 1996 Feb;137(2):431-7.

PMID:
8593786
26.

Cortisol increases interstitial collagenase expression in osteoblasts by post-transcriptional mechanisms.

Delany AM, Jeffrey JJ, Rydziel S, Canalis E.

J Biol Chem. 1995 Nov 3;270(44):26607-12.

28.
29.

Insulin-like growth factors inhibit interstitial collagenase synthesis in bone cell cultures.

Canalis E, Rydziel S, Delany AM, Varghese S, Jeffrey JJ.

Endocrinology. 1995 Apr;136(4):1348-54.

PMID:
7895645
31.

Identification of a specific receptor for interstitial collagenase on osteoblastic cells.

Omura TH, Noguchi A, Johanns CA, Jeffrey JJ, Partridge NC.

J Biol Chem. 1994 Oct 7;269(40):24994-8.

32.

Cloning and regulation of rat tissue inhibitor of metalloproteinases-2 in osteoblastic cells.

Cook TF, Burke JS, Bergman KD, Quinn CO, Jeffrey JJ, Partridge NC.

Arch Biochem Biophys. 1994 Jun;311(2):313-20.

PMID:
8203893
33.

Regulation of interstitial collagenase expression and collagen degradation by retinoic acid in bone cells.

Varghese S, Rydziel S, Jeffrey JJ, Canalis E.

Endocrinology. 1994 Jun;134(6):2438-44.

PMID:
8194470
35.

Regulation of uterine collagenase gene expression: interactions between serotonin and progesterone.

Wilcox BD, Rydelek-Fitzgerald L, Jeffrey JJ.

Mol Cell Endocrinol. 1994 May;101(1-2):67-75.

PMID:
9397938
36.

A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability.

Partridge CA, Jeffrey JJ, Malik AB.

Am J Physiol. 1993 Nov;265(5 Pt 1):L438-47.

PMID:
8238531
37.

Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.

Rydelek-Fitzgerald L, Wilcox BD, Teitler M, Jeffrey JJ.

Mol Cell Endocrinol. 1993 Apr;92(2):253-9.

PMID:
8319829
38.

The acute phase reactant serum amyloid A (SAA3) is a novel substrate for degradation by the metalloproteinases collagenase and stromelysin.

Mitchell TI, Jeffrey JJ, Palmiter RD, Brinckerhoff CE.

Biochim Biophys Acta. 1993 Mar 21;1156(3):245-54.

PMID:
8461313
39.

Extracellular-matrix degradation at acid pH. Avian osteoclast acid collagenase isolation and characterization.

Blair HC, Teitelbaum SL, Grosso LE, Lacey DL, Tan HL, McCourt DW, Jeffrey JJ.

Biochem J. 1993 Mar 15;290 ( Pt 3):873-84.

40.

Serotonin-dependent collagenase induction in rat myometrial smooth muscle cells: mediation by the 5-HT2 receptor.

Rydelek-Fitzgerald L, Wilcox BD, Teitler M, Jeffrey JJ.

Mol Cell Endocrinol. 1993 Feb;91(1-2):67-74.

PMID:
8472855
41.

Regulation of collagenase gene expression by serotonin and progesterone in rat uterine smooth muscle cells.

Wilcox BD, Rydelek-Fitzgerald L, Jeffrey JJ.

J Biol Chem. 1992 Oct 15;267(29):20752-7.

42.

Purification and characterization of bovine interstitial collagenase and tissue inhibitor of metalloproteinases.

Sudbeck BD, Jeffrey JJ, Welgus HG, Mecham RP, McCourt D, Parks WC.

Arch Biochem Biophys. 1992 Mar;293(2):370-6.

PMID:
1311165
43.

Purification and sequence analysis of two rat tissue inhibitors of metalloproteinases.

Roswit WT, McCourt DW, Partridge NC, Jeffrey JJ.

Arch Biochem Biophys. 1992 Feb 1;292(2):402-10.

PMID:
1309971
44.

Impaired bone activity in aged rats: alterations at the cellular and molecular levels.

Liang CT, Barnes J, Seedor JG, Quartuccio HA, Bolander M, Jeffrey JJ, Rodan GA.

Bone. 1992;13(6):435-41.

PMID:
1476822
45.

Recruitment of peripheral mononuclear cells by mammalian collagenase digests of type I collagen.

Malone JD, Richards M, Jeffrey JJ.

Matrix. 1991 Aug;11(4):289-95.

PMID:
1656175
46.

A serum factor promotes collagenase synthesis by an osteoblastic cell line.

Puccinelli JM, Omura TH, Strege DW, Jeffrey JJ, Partridge NC.

J Cell Physiol. 1991 Jun;147(3):505-13.

PMID:
1648567
47.

Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity.

Desrochers PE, Jeffrey JJ, Weiss SJ.

J Clin Invest. 1991 Jun;87(6):2258-65.

48.

Collagen and collagenase: pregnancy and parturition.

Jeffrey JJ.

Semin Perinatol. 1991 Apr;15(2):118-26. Review. No abstract available.

PMID:
1652159
49.

Serotonin: an inducer of collagenase in myometrial smooth muscle cells.

Jeffrey JJ, Ehlich LS, Roswit WT.

J Cell Physiol. 1991 Mar;146(3):399-406.

PMID:
1850749
50.

Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells.

Pacifici R, Carano A, Santoro SA, Rifas L, Jeffrey JJ, Malone JD, McCracken R, Avioli LV.

J Clin Invest. 1991 Jan;87(1):221-8.

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