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Items: 1 to 50 of 109

1.

Cerebrospinal fluid and plasma neurofilament light relate to abnormal cognition.

Osborn KE, Khan OA, Kresge HA, Bown CW, Liu D, Moore EE, Gifford KA, Acosta LMY, Bell SP, Hohman TJ, Blennow K, Zetterberg H, Jefferson AL.

Alzheimers Dement (Amst). 2019 Oct 22;11:700-709. doi: 10.1016/j.dadm.2019.08.008. eCollection 2019 Dec.

2.

Sex differences in the genetic predictors of Alzheimer's pathology.

Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Deming Y, Chao MJ, Huentelman M, Martin ER, Hamilton-Nelson K, Shaw LM, Trojanowski JQ, Peskind ER, Cruchaga C, Pericak-Vance MA, Goate AM, Cox NJ, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M; Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative, Bennett DA, Schneider JA, Jefferson AL, Hohman TJ.

Brain. 2019 Sep 1;142(9):2581-2589. doi: 10.1093/brain/awz206.

PMID:
31497858
3.

Adverse Vascular Risk Relates to Cerebrospinal Fluid Biomarker Evidence of Axonal Injury in the Presence of Alzheimer's Disease Pathology.

Osborn KE, Alverio JM, Dumitrescu L, Pechman KR; Alzheimer’s Disease Neuroimaging Initiative, Gifford KA, Hohman TJ, Blennow K, Zetterberg H, Jefferson AL.

J Alzheimers Dis. 2019;71(1):281-290. doi: 10.3233/JAD-190077.

PMID:
31381510
4.

Apolipoprotein E Genotype Modifies the Association Between Cardiac Output and Cognition in Older Adults.

Bown CW, Liu D, Osborn KE, Gupta DK, Mendes LA, Pechman KR, Hohman TJ, Wang TJ, Gifford KA, Jefferson AL.

J Am Heart Assoc. 2019 Aug 6;8(15):e011146. doi: 10.1161/JAHA.118.011146. Epub 2019 Jul 31.

5.

Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.

Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ.

Mol Psychiatry. 2019 Jul 22. doi: 10.1038/s41380-019-0458-5. [Epub ahead of print]

PMID:
31332262
6.

Increasing copper concentrations do not affect Myxobolus cerebralis triactinomyxon viability.

Fetherman ER, Cadmus P, Jefferson AL, Hura MK.

J Fish Dis. 2019 Sep;42(9):1327-1331. doi: 10.1111/jfd.13048. Epub 2019 Jun 18. No abstract available.

PMID:
31210355
7.

Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia.

Gifford KA, Bell SP, Liu D, Neal JE, Turchan M, Shah AS, Jefferson AL.

J Am Geriatr Soc. 2019 Sep;67(9):1803-1811. doi: 10.1111/jgs.15972. Epub 2019 May 16.

PMID:
31095735
8.

Visual and Verbal Serial List Learning in Patients with Statistically-Determined Mild Cognitive Impairment.

Wasserman V, Emrani S, Matusz EF, Miller D, Garrett KD, Gifford KA, Hohman TJ, Jefferson AL, Au R, Swenson R, Libon DJ; Consortium for Clinical and Epidemiological Neuropsychological Data Analysis (CENDA).

Innov Aging. 2019 May 3;3(2):igz009. doi: 10.1093/geroni/igz009. eCollection 2019 May.

9.

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Alber J, Alladi S, Bae HJ, Barton DA, Beckett LA, Bell JM, Berman SE, Biessels GJ, Black SE, Bos I, Bowman GL, Brai E, Brickman AM, Callahan BL, Corriveau RA, Fossati S, Gottesman RF, Gustafson DR, Hachinski V, Hayden KM, Helman AM, Hughes TM, Isaacs JD, Jefferson AL, Johnson SC, Kapasi A, Kern S, Kwon JC, Kukolja J, Lee A, Lockhart SN, Murray A, Osborn KE, Power MC, Price BR, Rhodius-Meester HFM, Rondeau JA, Rosen AC, Rosene DL, Schneider JA, Scholtzova H, Shaaban CE, Silva NCBS, Snyder HM, Swardfager W, Troen AM, van Veluw SJ, Vemuri P, Wallin A, Wellington C, Wilcock DM, Xie SX, Hainsworth AH.

Alzheimers Dement (N Y). 2019 Apr 9;5:107-117. doi: 10.1016/j.trci.2019.02.001. eCollection 2019. Review.

10.

Perivascular spaces contribute to cognition beyond other small vessel disease markers.

Passiak BS, Liu D, Kresge HA, Cambronero FE, Pechman KR, Osborn KE, Gifford KA, Hohman TJ, Schrag MS, Davis LT, Jefferson AL.

Neurology. 2019 Mar 19;92(12):e1309-e1321. doi: 10.1212/WNL.0000000000007124. Epub 2019 Feb 27.

PMID:
30814324
11.

The 12-Word Philadelphia Verbal Learning Test Performances in Older Adults: Brain MRI and Cerebrospinal Fluid Correlates and Regression-Based Normative Data.

Gifford KA, Liu D, Neal JE, Babicz MA, Thompson JL, Walljasper LE, Wiggins ME, Turchan M, Pechman KR, Osborn KE, Acosta LMY, Bell SP, Hohman TJ, Libon DJ, Blennow K, Zetterberg H, Jefferson AL.

Dement Geriatr Cogn Dis Extra. 2018 Dec 6;8(3):476-491. doi: 10.1159/000494209. eCollection 2018 Sep-Dec.

12.

Neurofilament relates to white matter microstructure in older adults.

Moore EE, Hohman TJ, Badami FS, Pechman KR, Osborn KE, Acosta LMY, Bell SP, Babicz MA, Gifford KA, Anderson AW, Goldstein LE, Blennow K, Zetterberg H, Jefferson AL.

Neurobiol Aging. 2018 Oct;70:233-241. doi: 10.1016/j.neurobiolaging.2018.06.023. Epub 2018 Jun 28.

13.

Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults.

Jefferson AL, Cambronero FE, Liu D, Moore EE, Neal JE, Terry JG, Nair S, Pechman KR, Rane S, Davis LT, Gifford KA, Hohman TJ, Bell SP, Wang TJ, Beckman JA, Carr JJ.

Circulation. 2018 Oct 30;138(18):1951-1962. doi: 10.1161/CIRCULATIONAHA.118.032410.

14.

Sex-specific genetic predictors of Alzheimer's disease biomarkers.

Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ.

Acta Neuropathol. 2018 Dec;136(6):857-872. doi: 10.1007/s00401-018-1881-4. Epub 2018 Jul 2.

PMID:
29967939
15.

Increased Left Ventricular Mass Index Is Associated With Compromised White Matter Microstructure Among Older Adults.

Moore EE, Liu D, Pechman KR, Terry JG, Nair S, Cambronero FE, Bell SP, Gifford KA, Anderson AW, Hohman TJ, Carr JJ, Jefferson AL.

J Am Heart Assoc. 2018 Jun 26;7(13). pii: e009041. doi: 10.1161/JAHA.118.009041.

16.

Validity and Normative Data for the Biber Figure Learning Test: A Visual Supraspan Memory Measure.

Gifford KA, Liu D, Neal JE, Acosta LMY, Bell SP, Wiggins ME, Wisniewski KM, Godfrey M, Logan LA, Hohman TJ, Pechman KR, Libon DJ, Blennow K, Zetterberg H, Jefferson AL.

Assessment. 2018 May 1:1073191118773870. doi: 10.1177/1073191118773870. [Epub ahead of print]

17.

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL; Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2018 Aug 1;75(8):989-998. doi: 10.1001/jamaneurol.2018.0821.

18.

Cerebrospinal fluid β-amyloid42 and neurofilament light relate to white matter hyperintensities.

Osborn KE, Liu D, Samuels LR, Moore EE, Cambronero FE, Acosta LMY, Bell SP, Babicz MA, Gordon EA, Pechman KR, Davis LT, Gifford KA, Hohman TJ, Blennow K, Zetterberg H, Jefferson AL.

Neurobiol Aging. 2018 Aug;68:18-25. doi: 10.1016/j.neurobiolaging.2018.03.028. Epub 2018 Apr 3.

19.

APOE genotype modifies the association between central arterial stiffening and cognition in older adults.

Cambronero FE, Liu D, Neal JE, Moore EE, Gifford KA, Terry JG, Nair S, Pechman KR, Osborn KE, Hohman TJ, Bell SP, Sweatt JD, Wang TJ, Beckman JA, Carr JJ, Jefferson AL.

Neurobiol Aging. 2018 Jul;67:120-127. doi: 10.1016/j.neurobiolaging.2018.02.009. Epub 2018 Feb 20.

20.

Subclinical Compromise in Cardiac Strain Relates to Lower Cognitive Performances in Older Adults.

Kresge HA, Khan OA, Wagener MA, Liu D, Terry JG, Nair S, Cambronero FE, Gifford KA, Osborn KE, Hohman TJ, Pechman KR, Bell SP, Wang TJ, Carr JJ, Jefferson AL.

J Am Heart Assoc. 2018 Feb 13;7(4). pii: e007562. doi: 10.1161/JAHA.117.007562.

21.

Assessing Working Memory in Mild Cognitive Impairment with Serial Order Recall.

Emrani S, Libon DJ, Lamar M, Price CC, Jefferson AL, Gifford KA, Hohman TJ, Nation DA, Delano-Wood L, Jak A, Bangen KJ, Bondi MW, Brickman AM, Manly J, Swenson R, Au R; Consortium for Clinical and Epidemiological Neuropsychological Data Analysis (CENDA).

J Alzheimers Dis. 2018;61(3):917-928. doi: 10.3233/JAD-170555.

22.

APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer's Disease.

Hohman TJ, Dumitrescu L, Oksol A, Wagener M, Gifford KA, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

PLoS One. 2017 Nov 30;12(11):e0188501. doi: 10.1371/journal.pone.0188501. eCollection 2017.

23.

Late-Life Body Mass Index, Rapid Weight Loss, Apolipoprotein E ε4 and the Risk of Cognitive Decline and Incident Dementia.

Bell SP, Liu D, Samuels LR, Shah AS, Gifford KA, Hohman TJ, Jefferson AL.

J Nutr Health Aging. 2017;21(10):1259-1267. doi: 10.1007/s12603-017-0906-3.

24.

Lower cardiac index levels relate to lower cerebral blood flow in older adults.

Jefferson AL, Liu D, Gupta DK, Pechman KR, Watchmaker JM, Gordon EA, Rane S, Bell SP, Mendes LA, Davis LT, Gifford KA, Hohman TJ, Wang TJ, Donahue MJ.

Neurology. 2017 Dec 5;89(23):2327-2334. doi: 10.1212/WNL.0000000000004707. Epub 2017 Nov 8.

25.

Hemodynamic mechanisms underlying elevated oxygen extraction fraction (OEF) in moyamoya and sickle cell anemia patients.

Watchmaker JM, Juttukonda MR, Davis LT, Scott AO, Faraco CC, Gindville MC, Jordan LC, Cogswell PM, Jefferson AL, Kirshner HS, Donahue MJ.

J Cereb Blood Flow Metab. 2018 Sep;38(9):1618-1630. doi: 10.1177/0271678X16682509. Epub 2016 Dec 28.

26.

Insulin-like growth factor binding protein-2 interactions with Alzheimer's disease biomarkers.

Lane EM, Hohman TJ, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

Brain Imaging Behav. 2017 Dec;11(6):1779-1786. doi: 10.1007/s11682-016-9636-0.

27.

Asymptomatic Alzheimer disease: Defining resilience.

Hohman TJ, McLaren DG, Mormino EC, Gifford KA, Libon DJ, Jefferson AL; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2016 Dec 6;87(23):2443-2450. Epub 2016 Nov 4.

28.

Genetic resilience to amyloid related cognitive decline.

Hohman TJ, Dumitrescu L, Cox NJ, Jefferson AL; Alzheimer’s Neuroimaging Initiative.

Brain Imaging Behav. 2017 Apr;11(2):401-409. doi: 10.1007/s11682-016-9615-5.

29.

Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury.

Marelli A, Miller SP, Marino BS, Jefferson AL, Newburger JW.

Circulation. 2016 May 17;133(20):1951-62. doi: 10.1161/CIRCULATIONAHA.115.019881. Review.

30.

The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview.

Jefferson AL, Gifford KA, Acosta LM, Bell SP, Donahue MJ, Davis LT, Gottlieb J, Gupta DK, Hohman TJ, Lane EM, Libon DJ, Mendes LA, Niswender K, Pechman KR, Rane S, Ruberg FL, Su YR, Zetterberg H, Liu D.

J Alzheimers Dis. 2016 Mar 8;52(2):539-59. doi: 10.3233/JAD-150914.

31.

Development of a subjective cognitive decline questionnaire using item response theory: a pilot study.

Gifford KA, Liu D, Romano R 3rd, Jones RN, Jefferson AL.

Alzheimers Dement (Amst). 2015 Dec 1;1(4):429-439.

32.

A Mutual Self- and Informant-Report of Cognitive Complaint Correlates with Neuropathological Outcomes in Mild Cognitive Impairment.

Gifford KA, Liu D, Hohman TJ, Xu M, Han X, Romano RR 3rd, Fritzsche LR, Abel T, Jefferson AL.

PLoS One. 2015 Nov 5;10(11):e0141831. doi: 10.1371/journal.pone.0141831. eCollection 2015.

33.

Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies.

Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chételat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, Luck T, Maruff P, Mielke MM, Molinuevo JL, Naeem F, Perrotin A, Petersen RC, Rami L, Reisberg B, Rentz DM, Riedel-Heller SG, Risacher SL, Rodriguez O, Sachdev PS, Saykin AJ, Slavin MJ, Snitz BE, Sperling RA, Tandetnik C, van der Flier WM, Wagner M, Wolfsgruber S, Sikkes SA.

J Alzheimers Dis. 2015 Sep 24;48 Suppl 1:S63-86. doi: 10.3233/JAD-150154.

34.

Associations between Verbal Learning Slope and Neuroimaging Markers across the Cognitive Aging Spectrum.

Gifford KA, Phillips JS, Samuels LR, Lane EM, Bell SP, Liu D, Hohman TJ, Romano RR 3rd, Fritzsche LR, Lu Z, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

J Int Neuropsychol Soc. 2015 Jul;21(6):455-67. doi: 10.1017/S1355617715000430.

35.

GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.

Hohman TJ, Chibnik L, Bush WS, Jefferson AL, De Jaeger PL, Thornton-Wells TA, Bennett DA, Schneider JA.

Neurotox Res. 2015 Oct;28(3):232-8. doi: 10.1007/s12640-015-9541-0. Epub 2015 Jul 21.

36.

Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes.

Hohman TJ, Samuels LR, Liu D, Gifford KA, Mukherjee S, Benson EM, Abel T, Ruberg FL, Jefferson AL; Alzheimer's Neuroimaging Initiative.

Neurobiol Aging. 2015 Sep;36(9):2501-8. doi: 10.1016/j.neurobiolaging.2015.05.021. Epub 2015 Jun 6.

37.

The role of vascular endothelial growth factor in neurodegeneration and cognitive decline: exploring interactions with biomarkers of Alzheimer disease.

Hohman TJ, Bell SP, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2015 May;72(5):520-9. doi: 10.1001/jamaneurol.2014.4761.

38.

Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study.

Jefferson AL, Beiser AS, Himali JJ, Seshadri S, O'Donnell CJ, Manning WJ, Wolf PA, Au R, Benjamin EJ.

Circulation. 2015 Apr 14;131(15):1333-9. doi: 10.1161/CIRCULATIONAHA.114.012438. Epub 2015 Feb 19.

39.

APOE and mild cognitive impairment: the Framingham Heart Study.

Jefferson AL, Beiser AS, Seshadri S, Wolf PA, Au R.

Age Ageing. 2015 Mar;44(2):307-11. doi: 10.1093/ageing/afu183. Epub 2014 Dec 11.

40.

Adverse vascular risk is related to cognitive decline in older adults.

Jefferson AL, Hohman TJ, Liu D, Haj-Hassan S, Gifford KA, Benson EM, Skinner JS, Lu Z, Sparling J, Sumner EC, Bell S, Ruberg FL.

J Alzheimers Dis. 2015;44(4):1361-73. doi: 10.3233/JAD-141812.

41.

Subjective memory complaint only relates to verbal episodic memory performance in mild cognitive impairment.

Gifford KA, Liu D, Damon SM, Chapman WG 4th, Romano Iii RR, Samuels LR, Lu Z, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2015;44(1):309-18. doi: 10.3233/JAD-140636.

42.

Inclusion of an informant yields strong associations between cognitive complaint and longitudinal cognitive outcomes in non-demented elders.

Gifford KA, Liu D, Carmona H, Lu Z, Romano R, Tripodis Y, Martin B, Kowall N, Jefferson AL.

J Alzheimers Dis. 2015;43(1):121-32. doi: 10.3233/JAD-131925.

43.

Vascular risk factors and midlife cognition: rethinking the exposure window.

Jefferson AL.

Circulation. 2014 Apr 15;129(15):1548-50. doi: 10.1161/CIRCULATIONAHA.114.008906. Epub 2014 Mar 31. No abstract available.

44.

Gray & white matter tissue contrast differentiates Mild Cognitive Impairment converters from non-converters.

Jefferson AL, Gifford KA, Damon S, Chapman GW 4th, Liu D, Sparling J, Dobromyslin V, Salat D; Alzheimer’s Disease Neuroimaging Initiative.

Brain Imaging Behav. 2015 Jun;9(2):141-8. doi: 10.1007/s11682-014-9291-2.

45.

The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults.

Gifford KA, Liu D, Lu Z, Tripodis Y, Cantwell NG, Palmisano J, Kowall N, Jefferson AL.

Alzheimers Dement. 2014 May;10(3):319-27. doi: 10.1016/j.jalz.2013.02.007. Epub 2013 Jul 16.

46.

Blood pressure and cognition among older adults: a meta-analysis.

Gifford KA, Badaracco M, Liu D, Tripodis Y, Gentile A, Lu Z, Palmisano J, Jefferson AL.

Arch Clin Neuropsychol. 2013 Nov;28(7):649-64. doi: 10.1093/arclin/act046. Epub 2013 Jul 9.

47.

An intervention to enhance Alzheimer's disease clinical research participation among older African Americans.

Jefferson AL, Lambe S, Romano RR, Liu D, Islam F, Kowall N.

J Alzheimers Dis. 2013;36(3):597-606. doi: 10.3233/JAD-130287.

48.

Diagnostic accuracy statistics for seven Neuropsychological Assessment Battery (NAB) test variables in the diagnosis of Alzheimer's disease.

Gavett BE, Lou KR, Daneshvar DH, Green RC, Jefferson AL, Stern RA.

Appl Neuropsychol Adult. 2012;19(2):108-15. doi: 10.1080/09084282.2011.643947.

49.

Medical student education program in Alzheimer's disease: the PAIRS Program.

Jefferson AL, Cantwell NG, Byerly LK, Morhardt D.

BMC Med Educ. 2012 Aug 21;12:80. doi: 10.1186/1472-6920-12-80.

50.

Clinical research risk assessment among individuals with mild cognitive impairment.

Jefferson AL, Carmona H, Gifford KA, Lambe S, Byerly LK, Cantwell NG, Tripodis Y, Karlawish J.

Am J Geriatr Psychiatry. 2012 Oct;20(10):878-86. doi: 10.1097/JGP.0b013e318252e5cb.

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