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The Conditional Probability of Vestibular Schwannoma Growth at Different Time Points after Initial Stability on an Observational Protocol.

Sethi M, Borsetto D, Cho Y, Gair J, Gamazo N, Jefferies S, Joannides A, Mannion R, Helmy A, Axon P, Donnelly N, Tysome JR, Bance M.

Otol Neurotol. 2019 Oct 11. doi: 10.1097/MAO.0000000000002448. [Epub ahead of print]


Surgery of the lateral skull base: a 50-year endeavour.

Zanoletti E, Mazzoni A, Martini A, Abbritti RV, Albertini R, Alexandre E, Baro V, Bartolini S, Bernardeschi D, Bivona R, Bonali M, Borghesi I, Borsetto D, Bovo R, Breun M, Calbucci F, Carlson ML, Caruso A, Cayé-Thomasen P, Cazzador D, Champagne PO, Colangeli R, Conte G, D'Avella D, Danesi G, Deantonio L, Denaro L, Di Berardino F, Draghi R, Ebner FH, Favaretto N, Ferri G, Fioravanti A, Froelich S, Giannuzzi A, Girasoli L, Grossardt BR, Guidi M, Hagen R, Hanakita S, Hardy DG, Iglesias VC, Jefferies S, Jia H, Kalamarides M, Kanaan IN, Krengli M, Landi A, Lauda L, Lepera D, Lieber S, Lloyd SLK, Lovato A, Maccarrone F, Macfarlane R, Magnan J, Magnoni L, Marchioni D, Marinelli JP, Marioni G, Mastronardi V, Matthies C, Moffat DA, Munari S, Nardone M, Pareschi R, Pavone C, Piccirillo E, Piras G, Presutti L, Restivo G, Reznitsky M, Roca E, Russo A, Sanna M, Sartori L, Scheich M, Shehata-Dieler W, Soloperto D, Sorrentino F, Sterkers O, Taibah A, Tatagiba M, Tealdo G, Vlad D, Wu H, Zanetti D.

Acta Otorhinolaryngol Ital. 2019 Jun;39(SUPPL. 1):S1-S146. doi: 10.14639/0392-100X-suppl.1-39-2019.


A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma.

Hall PE, Lewis R, Syed N, Shaffer R, Evanson J, Ellis S, Williams M, Feng X, Johnston A, Thomson JA, Harris FP, Jena R, Matys T, Jefferies S, Smith K, Wu BW, Bomalaski JS, Crook T, O'Neill K, Paraskevopoulos D, Khadeir RS, Sheaff M, Pacey S, Plowman PN, Szlosarek PW.

Clin Cancer Res. 2019 May 1;25(9):2708-2716. doi: 10.1158/1078-0432.CCR-18-3729. Epub 2019 Feb 22.


Incidence of second and higher order smoking-related primary cancers following lung cancer: a population-based cohort study.

Barclay ME, Lyratzopoulos G, Walter FM, Jefferies S, Peake MD, Rintoul RC.

Thorax. 2019 May;74(5):466-472. doi: 10.1136/thoraxjnl-2018-212456. Epub 2019 Feb 18.


Uncommon low-grade brain tumors.

Ajithkumar T, Imbulgoda N, Rees E, Harris F, Horan G, Burke A, Jefferies S, Price S, Cross J, Allinson K.

Neuro Oncol. 2019 Feb 14;21(2):151-166. doi: 10.1093/neuonc/noy151.


Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord.

Noble DJ, Yeap PL, Seah SYK, Harrison K, Shelley LEA, Romanchikova M, Bates AM, Zheng Y, Barnett GC, Benson RJ, Jefferies SJ, Thomas SJ, Jena R, Burnet NG.

Radiother Oncol. 2019 Jan;130:32-38. doi: 10.1016/j.radonc.2018.07.009. Epub 2018 Jul 23.


Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma: A phase-II parallel non-randomized and observation study (EORTC 22042-26042).

Weber DC, Ares C, Villa S, Peerdeman SM, Renard L, Baumert BG, Lucas A, Veninga T, Pica A, Jefferies S, Ricardi U, Miralbell R, Stelmes JJ, Liu Y, Collette L, Collette S.

Radiother Oncol. 2018 Aug;128(2):260-265. doi: 10.1016/j.radonc.2018.06.018. Epub 2018 Jun 28.


Identifying risk factors for L'Hermitte's sign after IMRT for head and neck cancer.

Laidley HM, Noble DJ, Barnett GC, Forman JR, Bates AM, Benson RJ, Jefferies SJ, Jena R, Burnet NG.

Radiat Oncol. 2018 May 4;13(1):84. doi: 10.1186/s13014-018-1015-0.


PARADIGM-2: Two parallel phase I studies of olaparib and radiotherapy or olaparib and radiotherapy plus temozolomide in patients with newly diagnosed glioblastoma, with treatment stratified by MGMT status.

Fulton B, Short SC, James A, Nowicki S, McBain C, Jefferies S, Kelly C, Stobo J, Morris A, Williamson A, Chalmers AJ.

Clin Transl Radiat Oncol. 2017 Nov 21;8:12-16. doi: 10.1016/j.ctro.2017.11.003. eCollection 2018 Jan.


Brain tumor research in the United Kingdom: current perspective and future challenges. A strategy document from the NCRI Brain Tumor CSG.

Kurian KM, Jenkinson MD, Brennan PM, Grant R, Jefferies S, Rooney AG, Bulbeck H, Erridge SC, Mills S, McBain C, McCabe MG, Price SJ, Marino S, Moyes E, Qian W, Waldman A, Vaqas B, Keatley D, Burchill P, Watts C.

Neurooncol Pract. 2018 Mar;5(1):10-17. doi: 10.1093/nop/npx022. Epub 2017 Aug 30. Review.


Aspirin does not prevent growth of vestibular schwannomas: A case-control study.

MacKeith S, Wasson J, Baker C, Guilfoyle M, John D, Donnelly N, Mannion R, Jefferies S, Axon P, Tysome JR.

Laryngoscope. 2018 Sep;128(9):2139-2144. doi: 10.1002/lary.27114. Epub 2018 Feb 6.


Tumour Volume and Dose Influence Outcome after Surgery and High-dose Photon Radiotherapy for Chordoma and Chondrosarcoma of the Skull Base and Spine.

Gatfield ER, Noble DJ, Barnett GC, Early NY, Hoole ACF, Kirkby NF, Jefferies SJ, Burnet NG.

Clin Oncol (R Coll Radiol). 2018 Apr;30(4):243-253. doi: 10.1016/j.clon.2018.01.002.


Applying physical science techniques and CERN technology to an unsolved problem in radiation treatment for cancer: the multidisciplinary 'VoxTox' research programme.

Burnet NG, Scaife JE, Romanchikova M, Thomas SJ, Bates AM, Wong E, Noble DJ, Shelley LE, Bond SJ, Forman JR, Hoole AC, Barnett GC, Brochu FM, Simmons MP, Jena R, Harrison K, Yeap PL, Drew A, Silvester E, Elwood P, Pullen H, Sultana A, Seah SY, Wilson MZ, Russell SG, Benson RJ, Rimmer YL, Jefferies SJ, Taku N, Gurnell M, Powlson AS, Schönlieb CB, Cai X, Sutcliffe MP, Parker MA.

CERN Ideasq J Exp Innov. 2017 Jun;1(1):3-12. doi: 10.23726/cij.2017.457.


Local alkylating chemotherapy applied immediately after 5-ALA guided resection of glioblastoma does not provide additional benefit.

Sage W, Guilfoyle M, Luney C, Young A, Sinha R, Sgubin D, McAbee JH, Ma R, Jefferies S, Jena R, Harris F, Allinson K, Matys T, Qian W, Santarius T, Price S, Watts C.

J Neurooncol. 2018 Jan;136(2):273-280. doi: 10.1007/s11060-017-2649-8. Epub 2017 Nov 14.


High flow or titrated oxygen for obese medical inpatients: a randomised crossover trial.

Pilcher J, Richards M, Eastlake L, McKinstry SJ, Bardsley G, Jefferies S, Braithwaite I, Weatherall M, Beasley R.

Med J Aust. 2017 Nov 20;207(10):430-434.


Automatic contour propagation using deformable image registration to determine delivered dose to spinal cord in head-and-neck cancer radiotherapy.

Yeap PL, Noble DJ, Harrison K, Bates AM, Burnet NG, Jena R, Romanchikova M, Sutcliffe MPF, Thomas SJ, Barnett GC, Benson RJ, Jefferies SJ, Parker MA.

Phys Med Biol. 2017 Jul 12;62(15):6062-6073. doi: 10.1088/1361-6560/aa76aa.


Analysis of heterogeneity in T2-weighted MR images can differentiate pseudoprogression from progression in glioblastoma.

Booth TC, Larkin TJ, Yuan Y, Kettunen MI, Dawson SN, Scoffings D, Canuto HC, Vowler SL, Kirschenlohr H, Hobson MP, Markowetz F, Jefferies S, Brindle KM.

PLoS One. 2017 May 17;12(5):e0176528. doi: 10.1371/journal.pone.0176528. eCollection 2017.


Effect of Heat Exposure and Simulated Physical Firefighting Work on Acute Inflammatory and Cortisol Responses.

Wolkow A, Aisbett B, Jefferies S, Main LC.

Ann Work Expo Health. 2017 Jun 1;61(5):600-603. doi: 10.1093/annweh/wxx029.


Highly Conformal Craniospinal Radiotherapy Techniques Can Underdose the Cranial Clinical Target Volume if Leptomeningeal Extension through Skull Base Exit Foramina is not Contoured.

Noble DJ, Ajithkumar T, Lambert J, Gleeson I, Williams MV, Jefferies SJ.

Clin Oncol (R Coll Radiol). 2017 Jul;29(7):439-447. doi: 10.1016/j.clon.2017.02.013. Epub 2017 Mar 18.


Prevention of radiotherapy-induced neurocognitive dysfunction in survivors of paediatric brain tumours: the potential role of modern imaging and radiotherapy techniques.

Ajithkumar T, Price S, Horan G, Burke A, Jefferies S.

Lancet Oncol. 2017 Feb;18(2):e91-e100. doi: 10.1016/S1470-2045(17)30030-X. Review.


A Study for Tooth Bleaching via Carbamide Peroxide-Loaded Hollow Calcium Phosphate Spheres.

Qin T, Mellgren T, Jefferies S, Xia W, Engqvist H.

Dent J (Basel). 2016 Dec 26;5(1). pii: E3. doi: 10.3390/dj5010003.


Minimally invasive surgery versus radiotherapy/chemoradiotherapy for small-volume primary oropharyngeal carcinoma.

Howard J, Masterson L, Dwivedi RC, Riffat F, Benson R, Jefferies S, Jani P, Tysome JR, Nutting C.

Cochrane Database Syst Rev. 2016 Dec 11;12:CD010963. doi: 10.1002/14651858.CD010963.pub2. Review.


Classification and Effects of Implant Surface Modification on the Bone: Human Cell-Based In Vitro Studies.

Ting M, Jefferies SR, Xia W, Engqvist H, Suzuki JB.

J Oral Implantol. 2017 Feb;43(1):58-83. doi: 10.1563/aaid-joi-D-16-00079. Epub 2016 Nov 29. Review.


Fast imaging employing steady-state acquisition (FIESTA) MRI to investigate cerebrospinal fluid (CSF) within dural reflections of posterior fossa cranial nerves.

Noble DJ, Scoffings D, Ajithkumar T, Williams MV, Jefferies SJ.

Br J Radiol. 2016 Nov;89(1067):20160392. Epub 2016 Sep 29.


A meta-analysis on the effect of implant characteristics on the survival of the wide-diameter implant.

Ting M, Palermo M, Donatelli DP, Gaughan JP, Suzuki JB, Jefferies SR.

Int J Implant Dent. 2015 Dec;1(1):28. Epub 2015 Nov 3. Review.


Atmospheric tomography for artificial satellite observations with a single guide star.

Hart M, Jefferies SM, Hope DA.

Opt Lett. 2016 Aug 15;41(16):3723-6. doi: 10.1364/OL.41.003723.


High-resolution speckle imaging through strong atmospheric turbulence.

Hope DA, Jefferies SM, Hart M, Nagy JG.

Opt Express. 2016 May 30;24(11):12116-29. doi: 10.1364/OE.24.012116.


A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma.

Rampling R, Peoples S, Mulholland PJ, James A, Al-Salihi O, Twelves CJ, McBain C, Jefferies S, Jackson A, Stewart W, Lindner J, Kutscher S, Hilf N, McGuigan L, Peters J, Hill K, Schoor O, Singh-Jasuja H, Halford SE, Ritchie JW.

Clin Cancer Res. 2016 Oct 1;22(19):4776-4785. Epub 2016 May 25.


Compressive fatigue limit of four types of dental restorative materials.

Chen S, Öhman C, Jefferies SR, Gray H, Xia W, Engqvist H.

J Mech Behav Biomed Mater. 2016 Aug;61:283-289. doi: 10.1016/j.jmbbm.2016.03.031. Epub 2016 Apr 5.


A Conversation on Adhesive Dentistry.

Reitz JV, Swift EJ Jr, Burgess JO, Jefferies SR, Walter R, Latta MA, Atlas AM.

Pa Dent J (Harrisb). 2016 Jan-Feb;83(1):14-7. No abstract available.


Critical Appraisal. Comparative Performance of Mineral Trioxide Aggregate Versus Calcium Hydroxide as a Direct Pulp Capping Agent.

Jefferies SR.

J Esthet Restor Dent. 2016 Mar-Apr;28(2):131-5. doi: 10.1111/jerd.12202. Epub 2016 Feb 15.


Randomized controlled trial of the effect of regular paracetamol on influenza infection.

Jefferies S, Braithwaite I, Walker S, Weatherall M, Jennings L, Luck M, Barrett K, Siebers R, Blackmore T, Beasley R, Perrin K; Pi Study Group.

Respirology. 2016 Feb;21(2):370-7. doi: 10.1111/resp.12685. Epub 2015 Dec 6.


Physical effects of non-cavitated explorer probing on enamel smooth-surface carious lesions.

Boston DW, Jefferies SR.

Am J Dent. 2015 Aug;28(4):183-9.


Evolving treatment options for melanoma brain metastases.

Ajithkumar T, Parkinson C, Fife K, Corrie P, Jefferies S.

Lancet Oncol. 2015 Oct;16(13):e486-97. doi: 10.1016/S1470-2045(15)00141-2. Review.


Conservative or radical surgery for pediatric papillary thyroid carcinoma: A systematic review of the literature.

Jin X, Masterson L, Patel A, Hook L, Nicholson J, Jefferies S, Gaze M, Nassif R, Eller R, Hulse T, Jani P.

Int J Pediatr Otorhinolaryngol. 2015 Oct;79(10):1620-4. doi: 10.1016/j.ijporl.2015.08.004. Epub 2015 Aug 10. Review.


Tumour progression or pseudoprogression? A review of post-treatment radiological appearances of glioblastoma.

Abdulla S, Saada J, Johnson G, Jefferies S, Ajithkumar T.

Clin Radiol. 2015 Nov;70(11):1299-312. doi: 10.1016/j.crad.2015.06.096. Epub 2015 Aug 10. Review.


Researcher, Dentist, PDA Member: A Conversation with Dr. Steven Jefferies.

Jefferies S, Terry BR.

Pa Dent J (Harrisb). 2015 Mar-Apr;82(2):16, 18-20. No abstract available.


Flexural strength and flexural fatigue properties of resin-modified glass ionomers.

Pameijer CH, Garcia-Godoy F, Morrow BR, Jefferies SR.

J Clin Dent. 2015;26(1):23-7.


Preliminary Evidence That Bioactive Cements Occlude Artificial Marginal Gaps.

Jefferies SR, Fuller AE, Boston DW.

J Esthet Restor Dent. 2015 May-Jun;27(3):155-66. doi: 10.1111/jerd.12133. Epub 2015 Jan 30.


Comment on "The role of imaging in the management of progressive glioblastoma. A systematic review and evidence-based clinical practice guideline" [J Neurooncol 2014; 118:435-460].

Booth TC, Waldman AD, Jefferies S, Jäger R.

J Neurooncol. 2015 Jan;121(2):423-4. doi: 10.1007/s11060-014-1649-1. Epub 2014 Nov 1. No abstract available.


Clinical and practical considerations for the use of intensity-modulated radiotherapy and image guidance in neuro-oncology.

Burnet NG, Jena R, Burton KE, Tudor GS, Scaife JE, Harris F, Jefferies SJ.

Clin Oncol (R Coll Radiol). 2014 Jul;26(7):395-406. doi: 10.1016/j.clon.2014.04.024. Epub 2014 May 17. Review.


Advances in remineralization for early carious lesions: a comprehensive review.

Jefferies SR.

Compend Contin Educ Dent. 2014 Apr;35(4):237-43; quiz 244. Review.


Current and investigational drug strategies for glioblastoma.

Ajaz M, Jefferies S, Brazil L, Watts C, Chalmers A.

Clin Oncol (R Coll Radiol). 2014 Jul;26(7):419-30. doi: 10.1016/j.clon.2014.03.012. Epub 2014 Apr 24. Review.


Physical properties and comparative strength of a bioactive luting cement.

Jefferies S, Lööf J, Pameijer CH, Boston D, Galbraith C, Hermansson L.

Compend Contin Educ Dent. 2013 Nov-Dec;34 Spec No 8:8-14.


Randomised placebo-controlled study of the effect of paracetamol on asthma severity in adults.

Ioannides SJ, Williams M, Jefferies S, Perrin K, Weatherall M, Siebers R, Crane J, Patel M, Travers J, Shirtcliffe P, Beasley R.

BMJ Open. 2014 Feb 12;4(2):e004324. doi: 10.1136/bmjopen-2013-004324.


Squamous cell carcinoma of the temporal bone: clinical outcomes from radical surgery and postoperative radiotherapy.

Masterson L, Rouhani M, Donnelly NP, Tysome JR, Patel P, Jefferies SJ, Roques T, Scrase C, Mannion R, Macfarlane R, Hardy D, Durrani A, Price R, Marker A, Axon P, Moffat DA.

Otol Neurotol. 2014 Mar;35(3):501-8. doi: 10.1097/MAO.0000000000000265.


Bioactive and biomimetic restorative materials: a comprehensive review. Part I.

Jefferies SR.

J Esthet Restor Dent. 2014 Jan-Feb;26(1):14-26. doi: 10.1111/jerd.12069. Epub 2013 Dec 17. Review.


Bioactive and biomimetic restorative materials: a comprehensive review. Part II.

Jefferies S.

J Esthet Restor Dent. 2014 Jan-Feb;26(1):27-39. doi: 10.1111/jerd.12066. Epub 2013 Dec 17. Review.


High grade glioma--the arrival of the molecular diagnostic era for patients over the age of 65 years in the UK.

Jefferies SJ, Harris FP, Price SJ, Collins VP, Watts C.

Clin Oncol (R Coll Radiol). 2013 Jul;25(7):391-3. doi: 10.1016/j.clon.2013.03.005. Epub 2013 Apr 21. No abstract available.


A bioactive dental luting cement--its retentive properties and 3-year clinical findings.

Jefferies SR, Pameijer CH, Appleby DC, Boston D, Lööf J.

Compend Contin Educ Dent. 2013 Feb;34 Spec No 1:2-9.


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