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Items: 16

1.

ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ.

Judith D, Jefferies HBJ, Boeing S, Frith D, Snijders AP, Tooze SA.

J Cell Biol. 2019 May 6;218(5):1634-1652. doi: 10.1083/jcb.201901115. Epub 2019 Mar 27.

2.

MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.

New M, Van Acker T, Sakamaki JI, Jiang M, Saunders RE, Long J, Wang VM, Behrens A, Cerveira J, Sudhakar P, Korcsmaros T, Jefferies HBJ, Ryan KM, Howell M, Tooze SA.

Cancer Res. 2019 Apr 15;79(8):1884-1898. doi: 10.1158/0008-5472.CAN-18-2553. Epub 2019 Feb 14.

PMID:
30765601
3.

Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.

Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, Dynlacht BD, Snijders AP, O'Reilly N, Jefferies HBJ, Tooze SA.

Curr Biol. 2017 Jul 24;27(14):2123-2136.e7. doi: 10.1016/j.cub.2017.06.021. Epub 2017 Jul 14.

4.

Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma.

McGrady NR, Minton AZ, Stankowska DL, He S, Jefferies HB, Krishnamoorthy RR.

BMC Neurosci. 2017 Mar 1;18(1):27. doi: 10.1186/s12868-017-0346-3.

5.

A switch from canonical to noncanonical autophagy shapes B cell responses.

Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD.

Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908.

6.

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.

Joachim J, Jefferies HB, Razi M, Frith D, Snijders AP, Chakravarty P, Judith D, Tooze SA.

Mol Cell. 2015 Dec 17;60(6):899-913. doi: 10.1016/j.molcel.2015.11.018.

7.

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.

Gomez-Sanchez JA, Carty L, Iruarrizaga-Lejarreta M, Palomo-Irigoyen M, Varela-Rey M, Griffith M, Hantke J, Macias-Camara N, Azkargorta M, Aurrekoetxea I, De Juan VG, Jefferies HB, Aspichueta P, Elortza F, Aransay AM, Martínez-Chantar ML, Baas F, Mato JM, Mirsky R, Woodhoo A, Jessen KR.

J Cell Biol. 2015 Jul 6;210(1):153-68. doi: 10.1083/jcb.201503019.

8.

Assessing mammalian autophagy.

Tooze SA, Dooley HC, Jefferies HB, Joachim J, Judith D, Lamb CA, Razi M, Wirth M.

Methods Mol Biol. 2015;1270:155-65. doi: 10.1007/978-1-4939-2309-0_12.

PMID:
25702116
9.

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.

McKnight NC, Jefferies HB, Alemu EA, Saunders RE, Howell M, Johansen T, Tooze SA.

EMBO J. 2012 Apr 18;31(8):1931-46. doi: 10.1038/emboj.2012.36. Epub 2012 Feb 21.

10.

Trafficking and signaling in mammalian autophagy.

Tooze SA, Jefferies HB, Kalie E, Longatti A, McAlpine FE, McKnight NC, Orsi A, Polson HE, Razi M, Robinson DJ, Webber JL.

IUBMB Life. 2010 Jul;62(7):503-8. doi: 10.1002/iub.334. Review.

11.

In vitro reconstitution of fusion between immature autophagosomes and endosomes.

Morvan J, Köchl R, Watson R, Collinson LM, Jefferies HB, Tooze SA.

Autophagy. 2009 Jul;5(5):676-89. Epub 2009 Jul 6.

PMID:
19337031
12.

A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding.

Jefferies HB, Cooke FT, Jat P, Boucheron C, Koizumi T, Hayakawa M, Kaizawa H, Ohishi T, Workman P, Waterfield MD, Parker PJ.

EMBO Rep. 2008 Feb;9(2):164-70. doi: 10.1038/sj.embor.7401155. Epub 2008 Jan 11.

13.

Analysis of the transcriptional program induced by Raf in epithelial cells.

Schulze A, Lehmann K, Jefferies HB, McMahon M, Downward J.

Genes Dev. 2001 Apr 15;15(8):981-94.

14.

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

Jefferies HB, Fumagalli S, Dennis PB, Reinhard C, Pearson RB, Thomas G.

EMBO J. 1997 Jun 16;16(12):3693-704.

15.

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family.

Jefferies HB, Reinhard C, Kozma SC, Thomas G.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4441-5.

16.

Elongation factor-1 alpha mRNA is selectively translated following mitogenic stimulation.

Jefferies HB, Thomas G, Thomas G.

J Biol Chem. 1994 Feb 11;269(6):4367-72.

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