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Items: 1 to 50 of 171

1.

Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells.

Walker EM, Slisarenko N, Gerrets GL, Kissinger PJ, Didier ES, Kuroda MJ, Veazey RS, Jazwinski SM, Rout N.

Geroscience. 2019 Nov 11. doi: 10.1007/s11357-019-00099-7. [Epub ahead of print]

PMID:
31713098
2.

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects.

Patel TH, Norman L, Chang S, Abedi S, Liu C, Chwa M, Atilano SR, Thaker K, Lu S, Jazwinski SM, Miceli MV, Udar N, Bota D, Kenney MC.

Front Oncol. 2019 Jul 19;9:640. doi: 10.3389/fonc.2019.00640. eCollection 2019.

3.

Examination of the Dimensions of Biological Age.

Jazwinski SM, Kim S.

Front Genet. 2019 Mar 26;10:263. doi: 10.3389/fgene.2019.00263. eCollection 2019. Review.

4.

Exome sequencing reveals a novel COL2A1 mutation implicated in multiple epiphyseal dysplasia.

Dasa V, Eastwood JRB, Podgorski M, Park H, Blackstock C, Antoshchenko T, Rogala P, Bieganski T, Jazwinski SM, Czarny-Ratajczak M.

Am J Med Genet A. 2019 Apr;179(4):534-541. doi: 10.1002/ajmg.a.61049. Epub 2019 Feb 10.

PMID:
30740902
5.

Memory Self-Efficacy and Beliefs about Memory and Aging in Oldest-Old Adults in the Louisiana Healthy Aging Study (LHAS).

Cherry KE, Lyon BA, Boudreaux EO, Blanchard AB, Hicks JL, Elliott EM, Myers L, Kim S, Jazwinski SM.

Exp Aging Res. 2019 Jan-Feb;45(1):28-40. doi: 10.1080/0361073X.2018.1560107. Epub 2019 Feb 1.

PMID:
30707652
6.

Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response.

Jiang JC, Stumpferl SW, Jazwinski SM.

Biogerontology. 2019 Feb;20(1):93-107. doi: 10.1007/s10522-018-9779-z. Epub 2018 Oct 8.

PMID:
30298458
7.

Body Composition, IGF1 Status, and Physical Functionality in Nonagenarians: Implications for Osteosarcopenia.

Poggiogalle E, Cherry KE, Su LJ, Kim S, Myers L, Welsh DA, Jazwinski SM, Ravussin E.

J Am Med Dir Assoc. 2019 Jan;20(1):70-75.e2. doi: 10.1016/j.jamda.2018.07.007. Epub 2018 Aug 24.

PMID:
30149984
8.

DNA methylation associated with healthy aging of elderly twins.

Kim S, Wyckoff J, Morris AT, Succop A, Avery A, Duncan GE, Jazwinski SM.

Geroscience. 2018 Dec;40(5-6):469-484. doi: 10.1007/s11357-018-0040-0. Epub 2018 Aug 22.

9.

The Gut Microbiota and Healthy Aging: A Mini-Review.

Kim S, Jazwinski SM.

Gerontology. 2018;64(6):513-520. doi: 10.1159/000490615. Epub 2018 Jul 19. Review.

10.

cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.

Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, Ambati M, Ambati VL, Kajiwara Y, Ambati K, Hirahara S, Bastos-Carvalho A, Ogura Y, Terasaki H, Oshika T, Kim KB, Hinton DR, Leitinger N, Cambier JC, Buxbaum JD, Kenney MC, Jazwinski SM, Nagai H, Hara I, West AP, Fitzgerald KA, Sadda SR, Gelfand BD, Ambati J.

Nat Med. 2018 Jan;24(1):50-61. doi: 10.1038/nm.4450. Epub 2017 Nov 27.

11.

Adaptation to metabolic dysfunction during aging: Making the best of a bad situation.

Jazwinski SM, Jiang JC, Kim S.

Exp Gerontol. 2018 Jul 1;107:87-90. doi: 10.1016/j.exger.2017.07.013. Epub 2017 Jul 29. Review.

12.

Metabolic and Genetic Markers of Biological Age.

Jazwinski SM, Kim S.

Front Genet. 2017 May 23;8:64. doi: 10.3389/fgene.2017.00064. eCollection 2017.

13.

Biological Aging and the Human Gut Microbiota.

Maffei VJ, Kim S, Blanchard E 4th, Luo M, Jazwinski SM, Taylor CM, Welsh DA.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1474-1482. doi: 10.1093/gerona/glx042.

14.

The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age.

Kim S, Myers L, Wyckoff J, Cherry KE, Jazwinski SM.

Geroscience. 2017 Feb;39(1):83-92. doi: 10.1007/s11357-017-9960-3. Epub 2017 Jan 14.

15.

The Knowledge of Memory Aging Questionnaire: Factor Structure and Correlates in a Lifespan Sample.

Calamia M, Reese-Melancon C, Cherry KE, Hawley KS, Jazwinski SM.

Yale J Biol Med. 2016 Mar 24;89(1):91-6. eCollection 2016 Mar. Review.

16.

Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae.

Jiang JC, Stumpferl SW, Tiwari A, Qin Q, Rodriguez-Quiñones JF, Jazwinski SM.

Genetics. 2016 Oct;204(2):659-673. Epub 2016 Jul 29.

17.

Looking for the Silver Lining: Benefit Finding after Hurricanes Katrina and Rita in Middle-Aged, Older, and Oldest-Old Adults.

Stanko KE, Cherry KE, Ryker KS, Mughal F, Marks LD, Brown JS, Gendusa PF, Sullivan MC, Bruner J, Welsh DA, Su LJ, Jazwinski SM.

Curr Psychol. 2015 Sep;34(3):564-575. Epub 2015 Aug 15.

18.

Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA.

Thaker K, Chwa M, Atilano SR, Coskun P, Cáceres-Del-Carpio J, Udar N, Boyer DS, Jazwinski SM, Miceli MV, Nesburn AB, Kuppermann BD, Kenney MC.

Neurobiol Dis. 2016 Sep;93:64-77. doi: 10.1016/j.nbd.2016.04.005. Epub 2016 Apr 22.

19.

Social Factors and Healthy Aging: Findings from the Louisiana Healthy Aging Study (LHAS).

Cherry KE, Brown JS, Kim S, Jazwinski SM.

Kinesiol Rev (Champaign). 2016 Feb;5(1):50-56.

20.

Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians.

Kim S, Myers L, Ravussin E, Cherry KE, Jazwinski SM.

Biogerontology. 2016 Aug;17(4):725-36. doi: 10.1007/s10522-016-9643-y. Epub 2016 Mar 10.

21.

Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae.

Zaman S, Choudhury M, Jiang JC, Srivastava P, Mohanty BK, Danielson C, Humphrey SJ, Jazwinski SM, Bastia D.

Mol Cell Biol. 2016 May 2;36(10):1451-63. doi: 10.1128/MCB.01100-15. Print 2016 May 15.

22.

Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians.

Kim S, Simon E, Myers L, Hamm LL, Jazwinski SM.

Gerontology. 2016;62(5):519-29. doi: 10.1159/000443793. Epub 2016 Feb 26.

23.

Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality.

Svenkrtova A, Belicova L, Volejnikova A, Sigler K, Jazwinski SM, Pichova A.

Biogerontology. 2016 Apr;17(2):395-408. doi: 10.1007/s10522-015-9625-5. Epub 2015 Nov 27.

24.

Brain pathologies in extreme old age.

Neltner JH, Abner EL, Jicha GA, Schmitt FA, Patel E, Poon LW, Marla G, Green RC, Davey A, Johnson MA, Jazwinski SM, Kim S, Davis D, Woodard JL, Kryscio RJ, Van Eldik LJ, Nelson PT.

Neurobiol Aging. 2016 Jan;37:1-11. doi: 10.1016/j.neurobiolaging.2015.10.009. Epub 2015 Oct 19.

25.

Mechanism of regulation of 'chromosome kissing' induced by Fob1 and its physiological significance.

Choudhury M, Zaman S, Jiang JC, Jazwinski SM, Bastia D.

Genes Dev. 2015 Jun 1;29(11):1188-201. doi: 10.1101/gad.260844.115.

26.

Quantitative measures of healthy aging and biological age.

Kim S, Jazwinski SM.

Healthy Aging Res. 2015;4. pii: 26.

27.

Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes.

Atilano SR, Malik D, Chwa M, Cáceres-Del-Carpio J, Nesburn AB, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N, Kenney MC.

Hum Mol Genet. 2015 Aug 15;24(16):4491-503. doi: 10.1093/hmg/ddv173. Epub 2015 May 10.

28.

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival.

Kim S, Welsh DA, Myers L, Cherry KE, Wyckoff J, Jazwinski SM.

Oncotarget. 2015 Feb 28;6(6):3600-12.

29.

The aging clock and circadian control of metabolism and genome stability.

Belancio VP, Blask DE, Deininger P, Hill SM, Jazwinski SM.

Front Genet. 2015 Jan 14;5:455. doi: 10.3389/fgene.2014.00455. eCollection 2014. Review.

30.

Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during aging.

Jazwinski SM.

Ageing Res Rev. 2015 Sep;23(Pt A):67-74. doi: 10.1016/j.arr.2014.12.007. Epub 2014 Dec 31. Review.

31.

The aging biological clock in Neurospora crassa.

Case ME, Griffith J, Dong W, Tigner IL, Gaines K, Jiang JC, Jazwinski SM, Arnold J; Georgia Centenarian Study.

Ecol Evol. 2014 Sep;4(17):3494-507. doi: 10.1002/ece3.1202. Epub 2014 Aug 22.

32.

Aging and health--a systems biology perspective. Introduction.

Jazwinski SM, Yashin AI.

Interdiscip Top Gerontol. 2015;40:VII-XII. No abstract available.

PMID:
25509217
33.

Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

Patwardhan GA, Hosain SB, Liu DX, Khiste SK, Zhao Y, Bielawski J, Jazwinski SM, Liu YY.

Biochim Biophys Acta. 2014 Nov;1841(11):1571-80. doi: 10.1016/j.bbalip.2014.08.017. Epub 2014 Sep 6.

34.

The retrograde response: a conserved compensatory reaction to damage from within and from without.

Jazwinski SM.

Prog Mol Biol Transl Sci. 2014;127:133-54. doi: 10.1016/B978-0-12-394625-6.00005-2. Review.

35.

Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae.

Ayyadevara S, Tazearslan C, Alla R, Jiang JC, Jazwinski SM, Shmookler Reis RJ.

Front Genet. 2014 Aug 4;5:211. doi: 10.3389/fgene.2014.00211. eCollection 2014.

36.

Human retinal transmitochondrial cybrids with J or H mtDNA haplogroups respond differently to ultraviolet radiation: implications for retinal diseases.

Malik D, Hsu T, Falatoonzadeh P, Cáceres-del-Carpio J, Tarek M, Chwa M, Atilano SR, Ramirez C, Nesburn AB, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N, Kenney MC.

PLoS One. 2014 Jun 11;9(2):e99003. doi: 10.1371/journal.pone.0099003. eCollection 2014.

37.

Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions.

Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Cáceres-del-Carpio J, Nesburn AB, Boyer DS, Kuppermann BD, Vawter M, Jazwinski SM, Miceli M, Wallace DC, Udar N.

Hum Mol Genet. 2014 Jul 1;23(13):3537-51. doi: 10.1093/hmg/ddu065. Epub 2014 Feb 28.

38.

Age group differences in positive and negative affect among oldest-old adults: findings from the Georgia Centenarian Study.

Cho J, Martin P, Poon LW; Georgia Centenarian Study, MacDonald M, Jazwinski SM, Green RC, Gearing M, Johnson MA, Markesbery WR, Woodard JL, Tenover JS, Siegler LC, Rott C, Rodgers WL, Hausman D, Arnold J, Davey A.

Int J Aging Hum Dev. 2013;77(4):261-88.

PMID:
24547613
39.

Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases.

Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Del Carpio JC, Nesburn AB, Boyer DS, Kuppermann BD, Vawter MP, Jazwinski SM, Miceli MV, Wallace DC, Udar N.

Biochim Biophys Acta. 2014 Feb;1842(2):208-19. doi: 10.1016/j.bbadis.2013.10.016. Epub 2013 Nov 4.

40.

An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively.

Kim S, Welsh DA, Ravussin E, Welsch MA, Cherry KE, Myers L, Jazwinski SM.

J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):650-6. doi: 10.1093/gerona/glt150. Epub 2013 Oct 25.

41.

APOE ϵ4, rated life experiences, and affect among centenarians.

Martin P, Jazwinski SM, Davey A, Green RC, Macdonald M, Margrett JA, Siegler IC, Arnold J, Woodard JL, Johnson MA, Kim S, Dai J, Li L, Batzer MA, Poon LW, For The Georgia Centenarian Study.

Aging Ment Health. 2014 Mar;18(2):240-7. doi: 10.1080/13607863.2013.827624. Epub 2013 Sep 2.

42.

Correlates of functional capacity among centenarians.

Martin P, MacDonald M, Margrett J, Siegler I, Poon LW, Jazwinski SM, Green RC, Gearing M, Markesbery WR, Woodard JL, Johnson MA, Tenover JS, Rodgers WL, Hausman D, Rott C, Davey A, Arnold J.

J Appl Gerontol. 2013 Apr;32(3):324-46. doi: 10.1177/0733464811420563. Epub 2011 Sep 19.

43.

Social engagement and health in younger, older, and oldest-old adults in the Louisiana Healthy Aging Study.

Cherry KE, Walker EJ, Brown JS, Volaufova J, LaMotte LR, Welsh DA, Su LJ, Jazwinski SM, Ellis R, Wood RH, Frisard MI.

J Appl Gerontol. 2013 Feb;32(1):51-75. doi: 10.1177/0733464811409034. Epub 2011 Jun 6.

44.

Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration.

Kenney MC, Chwa M, Atilano SR, Pavlis JM, Falatoonzadeh P, Ramirez C, Malik D, Hsu T, Woo G, Soe K, Nesburn AB, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N.

PLoS One. 2013;8(1):e54339. doi: 10.1371/journal.pone.0054339. Epub 2013 Jan 24.

45.

Left atrial enlargement and reduced physical function during aging.

Pellett AA, Myers L, Welsch M, Jazwinski SM, Welsh DA.

J Aging Phys Act. 2013 Oct;21(4):417-32. Epub 2012 Dec 10.

46.

Association of healthy aging with parental longevity.

Kim S, Welsh DA, Cherry KE, Myers L, Jazwinski SM.

Age (Dordr). 2013 Oct;35(5):1975-82. doi: 10.1007/s11357-012-9472-0. Epub 2012 Sep 18.

47.

Natural genetic variation in yeast longevity.

Stumpferl SW, Brand SE, Jiang JC, Korona B, Tiwari A, Dai J, Seo JG, Jazwinski SM.

Genome Res. 2012 Oct;22(10):1963-73. doi: 10.1101/gr.136549.111. Epub 2012 Sep 5.

48.

Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.

Gupta V, Bhinge KN, Hosain SB, Xiong K, Gu X, Shi R, Ho MY, Khoo KH, Li SC, Li YT, Ambudkar SV, Jazwinski SM, Liu YY.

J Biol Chem. 2012 Oct 26;287(44):37195-205. doi: 10.1074/jbc.M112.396390. Epub 2012 Aug 30.

49.

The yeast retrograde response as a model of intracellular signaling of mitochondrial dysfunction.

Jazwinski SM, Kriete A.

Front Physiol. 2012 May 17;3:139. doi: 10.3389/fphys.2012.00139. eCollection 2012.

50.

The retrograde response: when mitochondrial quality control is not enough.

Jazwinski SM.

Biochim Biophys Acta. 2013 Feb;1833(2):400-9. doi: 10.1016/j.bbamcr.2012.02.010. Epub 2012 Feb 21. Review.

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