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Items: 43


Dynamic interplay between enhancer-promoter topology and gene activity.

Chen H, Levo M, Barinov L, Fujioka M, Jaynes JB, Gregor T.

Nat Genet. 2018 Sep;50(9):1296-1303. doi: 10.1038/s41588-018-0175-z. Epub 2018 Jul 23.


Using competition assays to quantitatively model cooperative binding by transcription factors and other ligands.

Peacock J, Jaynes JB.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2789-2801. doi: 10.1016/j.bbagen.2017.07.024. Epub 2017 Aug 1.


Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes.

Chetverina D, Fujioka M, Erokhin M, Georgiev P, Jaynes JB, Schedl P.

Bioessays. 2017 Mar;39(3). doi: 10.1002/bies.201600233. Epub 2017 Jan 30. Review.


Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans.

Fujioka M, Mistry H, Schedl P, Jaynes JB.

PLoS Genet. 2016 Feb 24;12(2):e1005889. doi: 10.1371/journal.pgen.1005889. eCollection 2016 Feb.


Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D.

Lacin H, Rusch J, Yeh RT, Fujioka M, Wilson BA, Zhu Y, Robie AA, Mistry H, Wang T, Jaynes JB, Skeath JB.

Dev Biol. 2014 Apr 1;388(1):117-33. doi: 10.1016/j.ydbio.2014.01.029. Epub 2014 Feb 7.


The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading.

Fujioka M, Sun G, Jaynes JB.

PLoS Genet. 2013 Oct;9(10):e1003883. doi: 10.1371/journal.pgen.1003883. Epub 2013 Oct 31.


Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.

Fujioka M, Gebelein B, Cofer ZC, Mann RS, Jaynes JB.

Dev Biol. 2012 Jun 15;366(2):382-92. doi: 10.1016/j.ydbio.2012.04.004. Epub 2012 Apr 20.


Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers.

Fujioka M, Jaynes JB.

Dev Biol. 2012 Feb 15;362(2):309-19. doi: 10.1016/j.ydbio.2011.12.001. Epub 2011 Dec 9.


Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development.

Johnston DM, Sedkov Y, Petruk S, Riley KM, Fujioka M, Jaynes JB, Mazo A.

Mol Cell. 2011 Oct 7;44(1):51-61. doi: 10.1016/j.molcel.2011.07.033.


A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication.

Fujioka M, Wu X, Jaynes JB.

Development. 2009 Sep;136(18):3077-87. doi: 10.1242/dev.036467. Epub 2009 Aug 12.


The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site.

Fujioka M, Yusibova GL, Zhou J, Jaynes JB.

Development. 2008 Dec;135(24):4131-9. doi: 10.1242/dev.024554.


The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila.

Khan FS, Fujioka M, Datta P, Fernandes-Alnemri T, Jaynes JB, Alnemri ES.

Cell Death Differ. 2008 Jun;15(6):1073-83. doi: 10.1038/cdd.2008.19. Epub 2008 Feb 15.


Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference.

Petruk S, Sedkov Y, Riley KM, Hodgson J, Schweisguth F, Hirose S, Jaynes JB, Brock HW, Mazo A.

Cell. 2006 Dec 15;127(6):1209-21.


Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan.

Fujioka M, Wessells RJ, Han Z, Liu J, Fitzgerald K, Yusibova GL, Zamora M, Ruiz-Lozano P, Bodmer R, Jaynes JB.

Circ Res. 2005 Nov 25;97(11):1108-14. Epub 2005 Oct 20.


Drawing lines in the sand: even skipped et al. and parasegment boundaries.

Jaynes JB, Fujioka M.

Dev Biol. 2004 May 15;269(2):609-22. Erratum in: Dev Biol. 2004 Aug 1;272(1):277-8.


Embryonic origins of a motor system: motor dendrites form a myotopic map in Drosophila.

Landgraf M, Jeffrey V, Fujioka M, Jaynes JB, Bate M.

PLoS Biol. 2003 Nov;1(2):E41. Epub 2003 Nov 17.


Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila.

Sedkov Y, Cho E, Petruk S, Cherbas L, Smith ST, Jones RS, Cherbas P, Canaani E, Jaynes JB, Mazo A.

Nature. 2003 Nov 6;426(6962):78-83.


Even-skipped, acting as a repressor, regulates axonal projections in Drosophila.

Fujioka M, Lear BC, Landgraf M, Yusibova GL, Zhou J, Riley KM, Patel NH, Jaynes JB.

Development. 2003 Nov;130(22):5385-400. Epub 2003 Sep 16.


Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila.

Kobayashi M, Fujioka M, Tolkunova EN, Deka D, Abu-Shaar M, Mann RS, Jaynes JB.

Development. 2003 Feb;130(4):741-51.


sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein.

Srinivasula SM, Datta P, Kobayashi M, Wu JW, Fujioka M, Hegde R, Zhang Z, Mukattash R, Fernandes-Alnemri T, Shi Y, Jaynes JB, Alnemri ES.

Curr Biol. 2002 Jan 22;12(2):125-30.


even skipped is required to produce a trans-acting signal for larval neuroblast proliferation that can be mimicked by ecdysone.

Park Y, Fujioka M, Kobayashi M, Jaynes JB, Datta S.

Development. 2001 May;128(10):1899-909.


Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries.

Kobayashi M, Goldstein RE, Fujioka M, Paroush Z, Jaynes JB.

Development. 2001 May;128(10):1805-15.


Production of transgenic Drosophila.

Fujioka M, Jaynes JB, Bejsovec A, Weir M.

Methods Mol Biol. 2000;136:353-63. Review. No abstract available.


[Developmental regulation by Drosophila Runt domain-proteins. Runt and Lozenge].

Hosoya T, Hiromi Y, Fujioka M, Jaynes JB.

Tanpakushitsu Kakusan Koso. 2000 Jan;45(1):7-12. Review. Japanese. No abstract available.


Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila.

Baines RA, Robinson SG, Fujioka M, Jaynes JB, Bate M.

Curr Biol. 1999 Nov 4;9(21):1267-70.


Drosophila homeobox gene eve enhances trol, an activator of neuroblast proliferation in the larval CNS.

Park Y, Fujioka M, Jaynes JB, Datta S.

Dev Genet. 1998;23(3):247-57.


Active repression of transcription by the engrailed homeodomain protein.

Jaynes JB, O'Farrell PH.

EMBO J. 1991 Jun;10(6):1427-33.


The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.

Jaynes JB, Johnson JE, Buskin JN, Gartside CL, Hauschka SD.

Mol Cell Biol. 1988 Jan;8(1):62-70.


Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.

Jaynes JB, Chamberlain JS, Buskin JN, Johnson JE, Hauschka SD.

Mol Cell Biol. 1986 Aug;6(8):2855-64.


Regulation of creatine kinase induction in differentiating mouse myoblasts.

Chamberlain JS, Jaynes JB, Hauschka SD.

Mol Cell Biol. 1985 Mar;5(3):484-92.


The mouse muscle creatine kinase cDNA and deduced amino acid sequences: comparison to evolutionarily related enzymes.

Buskin JN, Jaynes JB, Chamberlain JS, Hauschka SD.

J Mol Evol. 1985;22(4):334-41.


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