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Items: 1 to 50 of 115

1.

Use of Antibody Tools to Provide Serologic Evidence of Elimination of Lymphatic Filariasis in The Gambia.

Won KY, Sambou S, Barry A, Robinson K, Jaye M, Sanneh B, Sanyang A, Gass K, Lammie PJ, Rebollo M.

Am J Trop Med Hyg. 2018 Jan;98(1):15-20. doi: 10.4269/ajtmh.17-0371. Epub 2018 Jan 1.

2.

Elimination of lymphatic filariasis in the Gambia.

Rebollo MP, Sambou SM, Thomas B, Biritwum NK, Jaye MC, Kelly-Hope L, Escalada AG, Molyneux DH, Bockarie MJ.

PLoS Negl Trop Dis. 2015 Mar 18;9(3):e0003642. doi: 10.1371/journal.pntd.0003642. eCollection 2015 Mar.

3.

Continued decline of malaria in The Gambia with implications for elimination.

Ceesay SJ, Casals-Pascual C, Nwakanma DC, Walther M, Gomez-Escobar N, Fulford AJ, Takem EN, Nogaro S, Bojang KA, Corrah T, Jaye MC, Taal MA, Sonko AA, Conway DJ.

PLoS One. 2010 Aug 18;5(8):e12242. doi: 10.1371/journal.pone.0012242.

4.

The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages.

Marino JP Jr, Kallander LS, Ma C, Oh HJ, Lee D, Gaitanopoulos DE, Krawiec JA, Parks DJ, Webb CL, Ziegler K, Jaye M, Thompson SK.

Bioorg Med Chem Lett. 2009 Oct 1;19(19):5617-21. doi: 10.1016/j.bmcl.2009.08.036. Epub 2009 Aug 13.

PMID:
19717304
5.

Modified PAXgene method allows for isolation of high-integrity total RNA from microlitre volumes of mouse whole blood.

Krawiec JA, Chen H, Alom-Ruiz S, Jaye M.

Lab Anim. 2009 Oct;43(4):394-8. doi: 10.1258/la.2008.0070157. Epub 2009 Jun 5.

PMID:
19502296
6.

Heme-oxygenase induction inhibits arteriolar thrombosis in vivo: effect of the non-substrate inducer cobalt protoporphyrin.

Johns DG, Zelent D, Ao Z, Bradley BT, Cooke A, Contino L, Hu E, Douglas SA, Jaye MC.

Eur J Pharmacol. 2009 Mar 15;606(1-3):109-14. doi: 10.1016/j.ejphar.2008.12.030. Epub 2009 Jan 10.

PMID:
19168058
7.

Synthesis and SAR of potent LXR agonists containing an indole pharmacophore.

Washburn DG, Hoang TH, Campobasso N, Smallwood A, Parks DJ, Webb CL, Frank KA, Nord M, Duraiswami C, Evans C, Jaye M, Thompson SK.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1097-100. doi: 10.1016/j.bmcl.2009.01.004. Epub 2009 Jan 9.

PMID:
19167885
8.

Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors.

Goodman KB, Bury MJ, Cheung M, Cichy-Knight MA, Dowdell SE, Dunn AK, Lee D, Lieby JA, Moore ML, Scherzer DA, Sha D, Suarez DP, Murphy DJ, Harpel MR, Manas ES, McNulty DE, Annan RS, Matico RE, Schwartz BK, Trill JJ, Sweitzer TD, Wang DY, Keller PM, Krawiec JA, Jaye MC.

Bioorg Med Chem Lett. 2009 Jan 1;19(1):27-30. doi: 10.1016/j.bmcl.2008.11.033. Epub 2008 Nov 14.

PMID:
19058966
9.

Selective partial agonism of liver X receptor alpha is related to differential corepressor recruitment.

Phelan CA, Weaver JM, Steger DJ, Joshi S, Maslany JT, Collins JL, Zuercher WJ, Willson TM, Walker M, Jaye M, Lazar MA.

Mol Endocrinol. 2008 Oct;22(10):2241-9. doi: 10.1210/me.2008-0041. Epub 2008 Jul 31.

10.

A high-throughput screen for endothelial lipase using HDL as substrate.

Keller PM, Rust T, Murphy DJ, Matico R, Trill JJ, Krawiec JA, Jurewicz A, Jaye M, Harpel M, Thrall S, Schwartz B.

J Biomol Screen. 2008 Jul;13(6):468-75. doi: 10.1177/1087057108319738. Epub 2008 Jun 19.

PMID:
18566479
11.

Predominance of a proinflammatory phenotype in monocyte-derived macrophages from subjects with low plasma HDL-cholesterol.

Sarov-Blat L, Kiss RS, Haidar B, Kavaslar N, Jaye M, Bertiaux M, Steplewski K, Hurle MR, Sprecher D, McPherson R, Marcel YL.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1115-22. Epub 2007 Feb 22.

PMID:
17322100
12.

Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of beta-oxidation.

Larigauderie G, Cuaz-Pérolin C, Younes AB, Furman C, Lasselin C, Copin C, Jaye M, Fruchart JC, Rouis M.

FEBS J. 2006 Aug;273(15):3498-510.

13.

Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats.

Johnston TP, Jaye M, Webb CL, Krawiec JA, Alom-Ruiz SP, Sachs-Barrable K, Wasan KM.

Eur J Pharmacol. 2006 May 1;536(3):232-40. Epub 2006 Mar 20.

PMID:
16603153
14.

Assessing the effects of LXR agonists on cellular cholesterol handling: a stable isotope tracer study.

Aravindhan K, Webb CL, Jaye M, Ghosh A, Willette RN, DiNardo NJ, Jucker BM.

J Lipid Res. 2006 Jun;47(6):1250-60. Epub 2006 Mar 27.

15.

Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages.

Larigauderie G, Bouhlel MA, Furman C, Jaye M, Fruchart JC, Rouis M.

Atherosclerosis. 2006 Nov;189(1):142-8. Epub 2006 Jan 24.

PMID:
16442115
16.

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo.

Naik SU, Wang X, Da Silva JS, Jaye M, Macphee CH, Reilly MP, Billheimer JT, Rothblat GH, Rader DJ.

Circulation. 2006 Jan 3;113(1):90-7. Epub 2005 Dec 19.

PMID:
16365197
17.

Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.

Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL.

J Med Chem. 2005 Aug 25;48(17):5419-22.

PMID:
16107141
18.

Synthetic LXR agonists increase LDL in CETP species.

Groot PH, Pearce NJ, Yates JW, Stocker C, Sauermelch C, Doe CP, Willette RN, Olzinski A, Peters T, d'Epagnier D, Morasco KO, Krawiec JA, Webb CL, Aravindhan K, Jucker B, Burgert M, Ma C, Marino JP, Collins JL, Macphee CH, Thompson SK, Jaye M.

J Lipid Res. 2005 Oct;46(10):2182-91. Epub 2005 Jul 16.

19.

REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.

Cuaz-Pérolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Nègre-Salvayre A, Fruchart JC, Rouis M.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1830-5. Epub 2004 Aug 12.

PMID:
15308555
20.

Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins.

Furman C, Rundlöf AK, Larigauderie G, Jaye M, Bricca G, Copin C, Kandoussi AM, Fruchart JC, Arnér ES, Rouis M.

Free Radic Biol Med. 2004 Jul 1;37(1):71-85.

PMID:
15183196
21.

Endothelial lipase and HDL metabolism.

Jaye M, Krawiec J.

Curr Opin Lipidol. 2004 Apr;15(2):183-9. Review.

PMID:
15017361
22.

Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis.

Larigauderie G, Furman C, Jaye M, Lasselin C, Copin C, Fruchart JC, Castro G, Rouis M.

Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):504-10. Epub 2004 Jan 5.

PMID:
14707038
23.

LXR agonists for the treatment of atherosclerosis.

Jaye M.

Curr Opin Investig Drugs. 2003 Sep;4(9):1053-8. Review.

PMID:
14582448
24.

Identification of novel isoform-selective inhibitors within class I histone deacetylases.

Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF, Johanson K, Liu R, Lago A, Hofmann G, Macarron R, de los Frailes M, Perez P, Krawiec J, Winkler J, Jaye M.

J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15.

PMID:
12975486
25.

Hypoxia induces the expression of the pro-apoptotic gene BNIP3.

Guo K, Searfoss G, Krolikowski D, Pagnoni M, Franks C, Clark K, Yu KT, Jaye M, Ivashchenko Y.

Cell Death Differ. 2001 Apr;8(4):367-76.

26.

Therapeutic modulation of transcription factor activity.

Emery JG, Ohlstein EH, Jaye M.

Trends Pharmacol Sci. 2001 May;22(5):233-40. Review.

PMID:
11339974
27.

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.

Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, Teissier E, Minnich A, Jaye M, Duverger N, Brewer HB, Fruchart JC, Clavey V, Staels B.

Nat Med. 2001 Jan;7(1):53-8.

PMID:
11135616
28.

New thiol and sulfodiimine metalloproteinase inhibitors and their effect on human microvascular endothelial cell growth.

Sang QX, Jia MC, Schwartz MA, Jaye MC, Kleinman HK, Ghaffari MA, Luo YL.

Biochem Biophys Res Commun. 2000 Aug 11;274(3):780-6.

PMID:
10924354
29.

Endothelial lipase: a new member of the triglyceride lipase gene family.

Rader DJ, Jaye M.

Curr Opin Lipidol. 2000 Apr;11(2):141-7. Review.

PMID:
10787175
30.

A novel endothelial-derived lipase that modulates HDL metabolism.

Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, Doan K, South V, Amin D, Perrone M, Rader DJ.

Nat Genet. 1999 Apr;21(4):424-8.

PMID:
10192396
31.

Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide.

Ogura K, Nagata K, Hatanaka H, Habuchi H, Kimata K, Tate S, Ravera MW, Jaye M, Schlessinger J, Inagaki F.

J Biomol NMR. 1999 Jan;13(1):11-24.

PMID:
10070748
32.

Transforming growth factor-beta-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-XL downregulation.

Saltzman A, Munro R, Searfoss G, Franks C, Jaye M, Ivashchenko Y.

Exp Cell Res. 1998 Jul 10;242(1):244-54.

PMID:
9665822
33.

Structure of a heparin-linked biologically active dimer of fibroblast growth factor.

DiGabriele AD, Lax I, Chen DI, Svahn CM, Jaye M, Schlessinger J, Hendrickson WA.

Nature. 1998 Jun 25;393(6687):812-7.

PMID:
9655399
34.

Cloning and characterization of human Jak-2 kinase: high mRNA expression in immune cells and muscle tissue.

Saltzman A, Stone M, Franks C, Searfoss G, Munro R, Jaye M, Ivashchenko Y.

Biochem Biophys Res Commun. 1998 May 29;246(3):627-33.

PMID:
9618263
35.

hUBC9 associates with MEKK1 and type I TNF-alpha receptor and stimulates NFkappaB activity.

Saltzman A, Searfoss G, Marcireau C, Stone M, Ressner R, Munro R, Franks C, D'Alonzo J, Tocque B, Jaye M, Ivashchenko Y.

FEBS Lett. 1998 Apr 3;425(3):431-5.

36.

Monocyte chemoattractant protein-2 is a potent agonist of CCR2B.

Moore UM, Kaplow JM, Pleass RD, Castro SW, Naik K, Lynch CN, Daly S, Roach AG, Jaye M, Williams RJ.

J Leukoc Biol. 1997 Dec;62(6):911-5.

PMID:
9400834
37.

Ligand-binding specificity of human fibroblast growth factor receptor-3 IIIc.

Lin HY, Kaplow J, Jaye M, Hayman MJ.

FEBS Lett. 1997 Jul 14;411(2-3):389-92.

38.
39.

Analysis of putative heparin-binding domains of fibroblast growth factor-1. Using site-directed mutagenesis and peptide analogues.

Wong P, Hampton B, Szylobryt E, Gallagher AM, Jaye M, Burgess WH.

J Biol Chem. 1995 Oct 27;270(43):25805-11.

41.

Identification of novel peptide antagonists for von Willebrand factor binding to the platelet glycoprotein Ib receptor from a phage epitope library.

South V, Searfoss GH, French S, Cheadle C, Murray E, Howk R, Jaye M, Ricca GA.

Thromb Haemost. 1995 Jan;73(1):144-50.

PMID:
7537918
42.

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation.

Spivak-Kroizman T, Lemmon MA, Dikic I, Ladbury JE, Pinchasi D, Huang J, Jaye M, Crumley G, Schlessinger J, Lax I.

Cell. 1994 Dec 16;79(6):1015-24.

PMID:
7528103
43.

Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2.

Jabs EW, Li X, Scott AF, Meyers G, Chen W, Eccles M, Mao JI, Charnas LR, Jackson CE, Jaye M.

Nat Genet. 1994 Nov;8(3):275-9. Erratum in: Nat Genet 1995 Apr;9(4):451.

PMID:
7874170
44.

Identification of a Src SH3 domain binding motif by screening a random phage display library.

Cheadle C, Ivashchenko Y, South V, Searfoss GH, French S, Howk R, Ricca GA, Jaye M.

J Biol Chem. 1994 Sep 30;269(39):24034-9.

45.

Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells.

Spivak-Kroizman T, Mohammadi M, Hu P, Jaye M, Schlessinger J, Lax I.

J Biol Chem. 1994 May 20;269(20):14419-23.

46.

Mitogenic and in vitro angiogenic activity of human recombinant heparin affin regulatory peptide.

Laaroubi K, Delbé J, Vacherot F, Desgranges P, Tardieu M, Jaye M, Barritault D, Courty J.

Growth Factors. 1994;10(2):89-98.

PMID:
7520717
47.

A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs.

Unger EF, Banai S, Shou M, Jaklitsch M, Hodge E, Correa R, Jaye M, Epstein SE.

Cardiovasc Res. 1993 May;27(5):785-91.

PMID:
7688663
48.

Extracardiac to coronary anastomoses support regional left ventricular function in dogs.

Unger EF, Shou M, Sheffield CD, Hodge E, Jaye M, Epstein SE.

Am J Physiol. 1993 May;264(5 Pt 2):H1567-74.

PMID:
7684575
49.

The use of polymerase chain reaction for chromosome assignment.

Jaye M, Dionne CA.

Methods Mol Biol. 1993;15:89-94. doi: 10.1385/0-89603-244-2:89.

PMID:
21400267
50.

Chromosome assignment by polymerase chain reaction techniques.

Dionne CA, Jaye M.

Methods Enzymol. 1993;218:402-13. No abstract available.

PMID:
8510542

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