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Items: 1 to 50 of 60

1.

Differentiation of black tea infusions according to origin, processing and botanical varieties using multivariate statistical analysis of LC-MS data.

Shevchuk A, Jayasinghe L, Kuhnert N.

Food Res Int. 2018 Jul;109:387-402. doi: 10.1016/j.foodres.2018.03.059. Epub 2018 Mar 26. No abstract available.

PMID:
29803464
2.

Lipophilic extracts of Leucas zeylanica, a multi-purpose medicinal plant in the tropics, inhibit key enzymes involved in inflammation and gout.

Napagoda M, Gerstmeier J, Butschek H, Lorenz S, Kanatiwela D, Qader M, Nagahawatte A, De Soyza S, Wijayaratne GB, Svatoš A, Jayasinghe L, Koeberle A, Werz O.

J Ethnopharmacol. 2018 Oct 5;224:474-481. doi: 10.1016/j.jep.2018.04.042. Epub 2018 May 1.

PMID:
29727733
3.

Highly parallel direct RNA sequencing on an array of nanopores.

Garalde DR, Snell EA, Jachimowicz D, Sipos B, Lloyd JH, Bruce M, Pantic N, Admassu T, James P, Warland A, Jordan M, Ciccone J, Serra S, Keenan J, Martin S, McNeill L, Wallace EJ, Jayasinghe L, Wright C, Blasco J, Young S, Brocklebank D, Juul S, Clarke J, Heron AJ, Turner DJ.

Nat Methods. 2018 Mar;15(3):201-206. doi: 10.1038/nmeth.4577. Epub 2018 Jan 15.

PMID:
29334379
4.

Naphthoquinone Metabolites Produced by Monacrosporium ambrosium, the Ectosymbiotic Fungus of Tea Shot-Hole Borer, Euwallacea fornicatus, in Stems of Tea, Camellia sinensis.

Kehelpannala C, Kumar NS, Jayasinghe L, Araya H, Fujimoto Y.

J Chem Ecol. 2018 Jan;44(1):95-101. doi: 10.1007/s10886-017-0913-1. Epub 2018 Jan 2.

PMID:
29292470
5.

Chemical investigation of metabolites produced by an endophytic fungi Phialemonium curvatum from the leaves of Passiflora edulis.

Rathnayake GRN, Kumar NS, Jayasinghe L, Araya H, Fujimoto Y.

Nat Prod Res. 2017 Dec 20:1-4. doi: 10.1080/14786419.2017.1416373. [Epub ahead of print]

PMID:
29260908
6.

Intraoperative Optical Coherence Tomography Vault Measurement in Posterior Chamber Phakic Intraocular Lens Implantation.

Tan TE, Liu YC, Jayasinghe LS, Mehta JS.

J Refract Surg. 2017 Apr 1;33(4):274-277. doi: 10.3928/1081597X-20170111-05.

PMID:
28407168
7.

Factors influencing diurnal variation in height among adults.

Floyd B, Jayasinghe L, Dey C.

Homo. 2017 May;68(3):236-241. doi: 10.1016/j.jchb.2017.03.004. Epub 2017 Mar 19.

PMID:
28400060
8.

Bioassay-guided fractionation and identification of α-amylase inhibitors from Syzygium cumini leaves.

Poongunran J, Perera HK, Jayasinghe L, Fernando IT, Sivakanesan R, Araya H, Fujimoto Y.

Pharm Biol. 2017 Dec;55(1):206-211.

PMID:
27927056
9.

Photoprotective potential in some medicinal plants used to treat skin diseases in Sri Lanka.

Napagoda MT, Malkanthi BM, Abayawardana SA, Qader MM, Jayasinghe L.

BMC Complement Altern Med. 2016 Nov 24;16(1):479.

10.

Clinically malignant exophytic lesions in the background of oral submucous fibrosis: report of five cases.

Jayasinghe LA, Peiris PM, Tilakaratne WM, Attygalla AM, Jayasinghe RD, Sitheeque MA, Siriwardena BS.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Aug;122(2):210-5. doi: 10.1016/j.oooo.2016.06.001. Epub 2016 Jun 9.

PMID:
27422419
11.

Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly.

Podobnik M, Savory P, Rojko N, Kisovec M, Wood N, Hambley R, Pugh J, Wallace EJ, McNeill L, Bruce M, Liko I, Allison TM, Mehmood S, Yilmaz N, Kobayashi T, Gilbert RJ, Robinson CV, Jayasinghe L, Anderluh G.

Nat Commun. 2016 May 12;7:11598. doi: 10.1038/ncomms11598.

12.

A 3-Vinyl Cephem Derivative, a Useful Intermediate in the Synthesis of Cepham Antibiotics, from Aspergillus awamori Associated with Banana Fruit.

Bandara HM, Kumar NS, Jayasinghe L, Masubuti H, Fujimoto Y.

Nat Prod Commun. 2015 Oct;10(10):1663-6.

PMID:
26669099
13.

Endophytic Fungus Nigrospora oryzae from a Medicinal plant Coccinia grandis, a High Yielding New Source of Phenazine-1-carboxamide.

Thanabalasingam D, Kumar NS, Jayasinghe L, Fujimoto Y.

Nat Prod Commun. 2015 Oct;10(10):1659-60.

PMID:
26669097
14.
15.

Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction.

Liu YC, Jayasinghe L, Ang HP, Lwin NC, Yam GH, Mehta JS.

Biomed Res Int. 2015;2015:928608. doi: 10.1155/2015/928608. Epub 2015 Jul 27.

16.

Chemical investigation of metabolites produced by an endophytic Aspergillus sp. isolated from Limonia acidissima.

Siriwardane AM, Kumar NS, Jayasinghe L, Fujimoto Y.

Nat Prod Res. 2015;29(14):1384-7. doi: 10.1080/14786419.2015.1025230. Epub 2015 Mar 26.

PMID:
25809933
17.

Does ingestion of plants from a phenetic group of Monochoria ('Diyahabarala') cause hepatotoxicity?

Ileperuma V, Udage S, Yakandawala D, Jayasinghe L, Kumar S, Ratnatilleke A.

Ceylon Med J. 2015 Mar;60(1):28-30. doi: 10.4038/cmj.v60i1.8087. No abstract available.

18.

Risk of stillbirth at term and optimum timing of delivery in uncomplicated south Asian singleton pregnancies.

Dias T, Kumarasiri S, Wanigasekara R, Cooper D, Batuwitage C, Jayasinghe L, Padeniya T.

Ceylon Med J. 2014 Jun;59(2):54-8. doi: 10.4038/cmj.v59i2.7064.

19.

Accuracy of ultrasound estimated fetal weight formulae to predict actual birthweight after 34 weeks: prospective validation study.

Kumarasiri S, Wanigasekara R, Wahalawatta L, Jayasinghe L, Padeniya T, Dias T.

Ceylon Med J. 2013 Sep;58(3):116-21. doi: 10.4038/cmj.v58i3.6104.

20.

Rate of stunting among a sample of postwar resettled families in the Vanni Region: a study from the Mullaitivu District.

Ramanayaka RP, Sumanasekera RD, de Silva AH, Perera DP, Chandrasiri P, Gunasekera R, Jayasinghe LR.

Ceylon Med J. 2013 Jun;58(2):82-3. doi: 10.4038/cmj.v58i1.5363.

21.

Identification and characterization of proanthocyanidins of 16 members of the Rhododendron genus (Ericaceae) by tandem LC-MS.

Jaiswal R, Jayasinghe L, Kuhnert N.

J Mass Spectrom. 2012 Apr;47(4):502-15. doi: 10.1002/jms.2954.

PMID:
22689627
22.

Protein detection by nanopores equipped with aptamers.

Rotem D, Jayasinghe L, Salichou M, Bayley H.

J Am Chem Soc. 2012 Feb 8;134(5):2781-7. doi: 10.1021/ja2105653. Epub 2012 Jan 26.

23.

Knowledge and practices of paracetamol administration among caregivers of pediatric age group patients.

Ramanayake RP, Jayasinghe LR, De Silva AH, Wijesinghe WA, Kanaganayagam N.

J Family Med Prim Care. 2012 Jan;1(1):30-3. doi: 10.4103/2249-4863.94448.

24.

Phenolic constituents from the fruit juice of Flacourtia inermis.

Jayasinghe L, Lakdusinghe M, Hara N, Fujimoto Y.

Nat Prod Res. 2012;26(3):278-81. doi: 10.1080/14786419.2011.586638. Epub 2011 Oct 10.

PMID:
21985676
25.

Antioxidant flavonol glycosides from Elaeocarpus serratus and Filicium decipiens.

Jayasinghe L, Amarasinghe NR, Arundathie BG, Rupasinghe GK, Jayatilake NH, Fujimoto Y.

Nat Prod Res. 2012;26(8):717-21. doi: 10.1080/14786419.2010.551514. Epub 2011 Sep 19.

PMID:
21923561
26.

Subunit dimers of alpha-hemolysin expand the engineering toolbox for protein nanopores.

Hammerstein AF, Jayasinghe L, Bayley H.

J Biol Chem. 2011 Apr 22;286(16):14324-34. doi: 10.1074/jbc.M111.218164. Epub 2011 Feb 15.

27.

Continuous base identification for single-molecule nanopore DNA sequencing.

Clarke J, Wu HC, Jayasinghe L, Patel A, Reid S, Bayley H.

Nat Nanotechnol. 2009 Apr;4(4):265-70. doi: 10.1038/nnano.2009.12. Epub 2009 Feb 22.

PMID:
19350039
28.

Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.

Tian X, Switzer AG, Derose SA, Mishra RK, Solinsky MG, Mumin RN, Ebetino FH, Jayasinghe LR, Webster ME, Colson AO, Crossdoersen D, Pinney BB, Farmer JA, Dowty ME, Obringer CM, Cruze CA, Burklow ML, Suchanek PM, Dong L, Dirr MK, Sheldon RJ, Wos JA.

J Med Chem. 2008 Oct 9;51(19):6055-66. doi: 10.1021/jm800525p. Epub 2008 Sep 5.

PMID:
18771254
29.

Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines.

Arnoldi A, Dallavalle S, Merlini L, Musso L, Farina G, Moretti M, Jayasinghe L.

J Agric Food Chem. 2007 Oct 3;55(20):8187-92.

PMID:
17896810
30.

Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.

Tian X, Field TB, Switzer AG, Mazur AW, Ebetino FH, Wos JA, Berberich SM, Jayasinghe LR, Obringer CM, Dowty ME, Pinney BB, Farmer JA, Crossdoersen D, Sheldon RJ.

J Med Chem. 2006 Jul 27;49(15):4745-61.

PMID:
16854081
31.

Geranylated phenolic constituents from the fruits of Artocarpus nobilis.

Jayasinghe L, Rupasinghe GK, Hara N, Fujimoto Y.

Phytochemistry. 2006 Jul;67(13):1353-8. Epub 2006 May 30.

PMID:
16730759
32.

Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording.

Holden MA, Jayasinghe L, Daltrop O, Mason A, Bayley H.

Nat Chem Biol. 2006 Jun;2(6):314-8. Epub 2006 May 7.

PMID:
16680158
33.

N-Methyl-4-hydroxy-2-pyridinone analogues from Fusarium oxysporum.

Jayasinghe L, Abbas HK, Jacob MR, Herath WH, Nanayakkara NP.

J Nat Prod. 2006 Mar;69(3):439-42.

34.

Assembly of the Bi-component leukocidin pore examined by truncation mutagenesis.

Miles G, Jayasinghe L, Bayley H.

J Biol Chem. 2006 Jan 27;281(4):2205-14. Epub 2005 Nov 3.

35.
37.

Prepore for a breakthrough.

Bayley H, Jayasinghe L, Wallace M.

Nat Struct Mol Biol. 2005 May;12(5):385-6. No abstract available.

PMID:
15870725
38.

Functional engineered channels and pores (Review).

Bayley H, Jayasinghe L.

Mol Membr Biol. 2004 Jul-Aug;21(4):209-20. Review.

PMID:
15371010
39.

Geranyl chalcone derivatives with antifungal and radical scavenging properties from the leaves of Artocarpus nobilis.

Jayasinghe L, Balasooriya BA, Padmini WC, Hara N, Fujimoto Y.

Phytochemistry. 2004 May;65(9):1287-90.

PMID:
15184014
40.

A new 3,4-seco-lupane derivative from Lasianthus gardneri.

Dallavalle S, Jayasinghe L, Kumarihamy BM, Merlini L, Musso L, Scaglioni L.

J Nat Prod. 2004 May;67(5):911-3.

PMID:
15165165
41.

A new ecdysteroid, 2-deoxy-5beta,20-dihydroxyecdysone from the fruits of Diploclisia glaucescens.

Jayasinghe L, Mallika Kumarihamy BM, Suranga Arundathie BG, Dissanayake L, Hara N, Fujimoto Y.

Steroids. 2003 May;68(5):447-50.

PMID:
12798495
42.

Antifungal constituents of the stem bark of Bridelia retusa.

Jayasinghe L, Kumarihamy BM, Jayarathna KH, Udishani NW, Bandara BM, Hara N, Fujimoto Y.

Phytochemistry. 2003 Feb;62(4):637-41.

PMID:
12560039
43.

Bidesmosidic saponins from the fruits of Diploclisia glaucescens.

Jayasinghe L, Hara N, Fujimoto Y.

Phytochemistry. 2003 Feb;62(4):563-7.

PMID:
12560026
44.

3-Deoxy-1beta,20-dihydroxyecdysone from the leaves of Diploclisia glaucescens.

Jayasinghe L, Jayasooriya CP, Oyama K, Fujimoto Y.

Steroids. 2002 Jun;67(7):555-8.

PMID:
11996926
45.

Observation of predicted resonance structure in the H+D2 --> HD(v(') = 0, j(') = 7) + D reaction at a collision energy of 0.94 eV

Kendrick BK, Jayasinghe L, Moser S, Auzinsh M, Shafer-Ray N.

Phys Rev Lett. 2000 May 8;84(19):4325-8.

PMID:
10990677
46.

Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro.

Posner GH, Ploypradith P, Hapangama W, Wang D, Cumming JN, Dolan P, Kensler TW, Klinedinst D, Shapiro TA, Zheng QY, Murray CK, Pilkington LG, Jayasinghe LR, Bray JF, Daughenbaugh R.

Bioorg Med Chem. 1997 Jul;5(7):1257-65.

PMID:
9377085
47.

Butitaxel analogues: synthesis and structure-activity relationships.

Ali SM, Hoemann MZ, Aubé J, Georg GI, Mitscher LA, Jayasinghe LR.

J Med Chem. 1997 Jan 17;40(2):236-41.

PMID:
9003522
48.

Hederagenin glycosides from Pometia eximia.

Jayasinghe L, Shimada H, Hara N, Fujimoto Y.

Phytochemistry. 1995 Oct;40(3):891-7.

PMID:
7576458
49.

Novel cytotoxic 3'-(tert-butyl) 3'-dephenyl analogs of paclitaxel and docetaxel.

Ali SM, Hoemann MZ, Aubé J, Mitscher LA, Georg GI, McCall R, Jayasinghe LR.

J Med Chem. 1995 Sep 15;38(19):3821-8.

PMID:
7562913
50.

4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation.

Datta A, Jayasinghe LR, Georg GI.

J Med Chem. 1994 Nov 25;37(24):4258-60.

PMID:
7990125

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