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Items: 1 to 50 of 103

1.

Programming the Dynamic Control of Bacterial Gene Expression with a Chimeric Ligand- and Light-Based Promoter System.

Jayaraman P, Yeoh JW, Zhang J, Poh CL.

ACS Synth Biol. 2018 Nov 6. doi: 10.1021/acssynbio.8b00280. [Epub ahead of print]

PMID:
30359530
2.

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.

Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG.

Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018.

PMID:
30288358
3.

CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism.

Lertsuwan J, Lertsuwan K, Sawasdichai A, Tasnawijitwong N, Lee KY, Kitchen P, Afford S, Gaston K, Jayaraman PS, Satayavivad J.

Cancers (Basel). 2018 Aug 23;10(9). pii: E283. doi: 10.3390/cancers10090283.

4.

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development.

Gauvrit S, Villasenor A, Strilic B, Kitchen P, Collins MM, Marín-Juez R, Guenther S, Maischein HM, Fukuda N, Canham MA, Brickman JM, Bogue CW, Jayaraman PS, Stainier DYR.

Nat Commun. 2018 Jul 13;9(1):2704. doi: 10.1038/s41467-018-05039-1.

5.

Cell-Free Optogenetic Gene Expression System.

Jayaraman P, Yeoh JW, Jayaraman S, Teh AY, Zhang J, Poh CL.

ACS Synth Biol. 2018 Apr 20;7(4):986-994. doi: 10.1021/acssynbio.7b00422. Epub 2018 Apr 4.

PMID:
29596741
6.

AUDIOME: a tiered exome sequencing-based comprehensive gene panel for the diagnosis of heterogeneous nonsyndromic sensorineural hearing loss.

Guan Q, Balciuniene J, Cao K, Fan Z, Biswas S, Wilkens A, Gallo DJ, Bedoukian E, Tarpinian J, Jayaraman P, Sarmady M, Dulik M, Santani A, Spinner N, Abou Tayoun AN, Krantz ID, Conlin LK, Luo M.

Genet Med. 2018 Mar 29. doi: 10.1038/gim.2018.48. [Epub ahead of print]

PMID:
29595809
7.

Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism.

Wadey KS, Brown BA, Sala-Newby GB, Jayaraman PS, Gaston K, George SJ.

Vascul Pharmacol. 2017 Dec;99:34-44. doi: 10.1016/j.vph.2017.09.004. Epub 2017 Sep 18.

8.

Chitosan-nickel film based interferometric optical fiber sensor for label-free detection of histidine tagged proteins.

Ravikumar R, Chen LH, Jayaraman P, Poh CL, Chan CC.

Biosens Bioelectron. 2018 Jan 15;99:578-585. doi: 10.1016/j.bios.2017.08.012. Epub 2017 Aug 8.

PMID:
28826002
9.

Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth.

Kershaw RM, Roberts D, Wragg J, Shaaban AM, Humphreys E, Halsall J, Price L, Bicknell R, Gaston K, Jayaraman PS.

Oncogenesis. 2017 Jun 12;6(6):e346. doi: 10.1038/oncsis.2017.42.

10.

Globally Consistent Wrinkle-Aware Shading of Line Drawings.

Jayaraman PK, Fu CW, Zheng J, Liu X, Wong TT.

IEEE Trans Vis Comput Graph. 2018 Jul;24(7):2103-2117. doi: 10.1109/TVCG.2017.2705182. Epub 2017 May 17.

PMID:
28534776
11.

Repurposing a Two-Component System-Based Biosensor for the Killing of Vibrio cholerae.

Jayaraman P, Holowko MB, Yeoh JW, Lim S, Poh CL.

ACS Synth Biol. 2017 Jul 21;6(7):1403-1415. doi: 10.1021/acssynbio.7b00058. Epub 2017 May 5.

PMID:
28441472
12.

In Vivo Immune Responses of Cross-Linked Electrospun Tilapia Collagen Membrane<sup/>.

Hassanbhai AM, Lau CS, Wen F, Jayaraman P, Goh BT, Yu N, Teoh SH.

Tissue Eng Part A. 2017 Oct;23(19-20):1110-1119. doi: 10.1089/ten.tea.2016.0504. Epub 2017 Mar 30.

PMID:
28375819
13.

Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.

Nguyen TB, Jayaraman P, Bergseng E, Madhusudhan MS, Kim CY, Sollid LM.

J Biol Chem. 2017 Jun 2;292(22):9218-9228. doi: 10.1074/jbc.M117.785139. Epub 2017 Mar 31.

14.

CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation.

Siddiqui YH, Kershaw RM, Humphreys EH, Assis Junior EM, Chaudhri S, Jayaraman PS, Gaston K.

Oncogenesis. 2017 Jan 30;6(1):e293. doi: 10.1038/oncsis.2016.82.

15.

Internet of Things Platform for Smart Farming: Experiences and Lessons Learnt.

Jayaraman PP, Yavari A, Georgakopoulos D, Morshed A, Zaslavsky A.

Sensors (Basel). 2016 Nov 9;16(11). pii: E1884.

16.

IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection.

Booty MG, Barreira-Silva P, Carpenter SM, Nunes-Alves C, Jacques MK, Stowell BL, Jayaraman P, Beamer G, Behar SM.

Sci Rep. 2016 Nov 7;6:36720. doi: 10.1038/srep36720.

17.

Constructing Pairing-Friendly Elliptic Curves under Embedding Degree 1 for Securing Critical Infrastructures.

Wang M, Dai G, Choo KK, Jayaraman PP, Ranjan R.

PLoS One. 2016 Aug 26;11(8):e0161857. doi: 10.1371/journal.pone.0161857. eCollection 2016.

18.

Biosensing Vibrio cholerae with Genetically Engineered Escherichia coli.

Holowko MB, Wang H, Jayaraman P, Poh CL.

ACS Synth Biol. 2016 Nov 18;5(11):1275-1283. Epub 2016 Aug 30.

PMID:
27529184
19.

Generation of functional hepatocyte-like cells from human deciduous periodontal ligament stem cells.

Vasanthan P, Jayaraman P, Kunasekaran W, Lawrence A, Gnanasegaran N, Govindasamy V, Musa S, Kasim NH.

Naturwissenschaften. 2016 Aug;103(7-8):62. doi: 10.1007/s00114-016-1387-7. Epub 2016 Jul 5.

PMID:
27379400
20.

Blue light-mediated transcriptional activation and repression of gene expression in bacteria.

Jayaraman P, Devarajan K, Chua TK, Zhang H, Gunawan E, Poh CL.

Nucleic Acids Res. 2016 Aug 19;44(14):6994-7005. doi: 10.1093/nar/gkw548. Epub 2016 Jun 28.

21.

The adaptor molecule Trif contributes to murine host defense during Leptospiral infection.

Jayaraman PA, Devlin AA, Miller JC, Scholle F.

Immunobiology. 2016 Sep;221(9):964-74. doi: 10.1016/j.imbio.2016.05.006. Epub 2016 May 24.

PMID:
27259371
22.

Interactive High-Relief Reconstruction for Organic and Double-Sided Objects from a Photo.

Yeh CK, Huang SY, Jayaraman PK, Fu CW, Lee TY.

IEEE Trans Vis Comput Graph. 2017 Jul;23(7):1796-1808. doi: 10.1109/TVCG.2016.2574705. Epub 2016 Jun 1.

PMID:
27254869
23.

Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.

Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB.

J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4.

24.

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection.

Jayaraman P, Jacques MK, Zhu C, Steblenko KM, Stowell BL, Madi A, Anderson AC, Kuchroo VK, Behar SM.

PLoS Pathog. 2016 Mar 11;12(3):e1005490. doi: 10.1371/journal.ppat.1005490. eCollection 2016 Mar.

25.

Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion.

Gaston K, Tsitsilianos MA, Wadey K, Jayaraman PS.

Cell Biosci. 2016 Feb 13;6:12. doi: 10.1186/s13578-016-0077-7. eCollection 2016. Review.

26.

Multiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during Tuberculosis.

Booty MG, Nunes-Alves C, Carpenter SM, Jayaraman P, Behar SM.

J Immunol. 2016 Feb 15;196(4):1822-31. doi: 10.4049/jimmunol.1502206. Epub 2016 Jan 11.

27.

Controlled release of drugs in electrosprayed nanoparticles for bone tissue engineering.

Jayaraman P, Gandhimathi C, Venugopal JR, Becker DL, Ramakrishna S, Srinivasan DK.

Adv Drug Deliv Rev. 2015 Nov 1;94:77-95. doi: 10.1016/j.addr.2015.09.007. Epub 2015 Sep 28. Review.

PMID:
26415888
28.

2.5D Cartoon Hair Modeling and Manipulation.

Yeh CK, Jayaraman PK, Liu X, Fu CW, Lee TY.

IEEE Trans Vis Comput Graph. 2015 Mar;21(3):304-14. doi: 10.1109/TVCG.2014.2360406.

PMID:
26357063
29.

Expression patterns of immune genes in long-term cultured dental stem cells.

Jayaraman P, Govindasamy V, Gnanasegaran N, Kunasekaran W, Vasanthan P, Musa S, Kasim NH.

Clin Oral Investig. 2016 Jan;20(1):109-16. doi: 10.1007/s00784-015-1497-1. Epub 2015 Jun 6.

PMID:
26048030
30.

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.

Lu G, Zhang R, Geng S, Peng L, Jayaraman P, Chen C, Xu F, Yang J, Li Q, Zheng H, Shen K, Wang J, Liu X, Wang W, Zheng Z, Qi CF, Si C, He JC, Liu K, Lira SA, Sikora AG, Li L, Xiong H.

Nat Commun. 2015 Mar 27;6:6676. doi: 10.1038/ncomms7676.

31.

Requirement for innate immunity and CD90⁺ NK1.1⁻ lymphocytes to treat established melanoma with chemo-immunotherapy.

Moskalenko M, Pan M, Fu Y, de Moll EH, Hashimoto D, Mortha A, Leboeuf M, Jayaraman P, Bernardo S, Sikora AG, Wolchok J, Bhardwaj N, Merad M, Saenger Y.

Cancer Immunol Res. 2015 Mar;3(3):296-304. doi: 10.1158/2326-6066.CIR-14-0120. Epub 2015 Jan 19.

32.

Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.

Behar SM, Carpenter SM, Booty MG, Barber DL, Jayaraman P.

Semin Immunol. 2014 Dec;26(6):559-77. doi: 10.1016/j.smim.2014.09.003. Epub 2014 Oct 11. Review.

33.

iNOS expression in CD4+ T cells limits Treg induction by repressing TGFβ1: combined iNOS inhibition and Treg depletion unmask endogenous antitumor immunity.

Jayaraman P, Alfarano MG, Svider PF, Parikh F, Lu G, Kidwai S, Xiong H, Sikora AG.

Clin Cancer Res. 2014 Dec 15;20(24):6439-51. doi: 10.1158/1078-0432.CCR-13-3409. Epub 2014 Oct 2.

34.

Improved rat genome gene prediction by integration of ESTs with RNA-Seq information.

Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P, Lu Y.

Bioinformatics. 2015 Jan 1;31(1):25-32. doi: 10.1093/bioinformatics/btu608. Epub 2014 Sep 12.

35.

In search of a new paradigm for protective immunity to TB.

Nunes-Alves C, Booty MG, Carpenter SM, Jayaraman P, Rothchild AC, Behar SM.

Nat Rev Microbiol. 2014 Apr;12(4):289-99. doi: 10.1038/nrmicro3230. Epub 2014 Mar 3. Review.

36.

Treatment planning methods in high dose rate interstitial brachytherapy of carcinoma cervix: a dosimetric and radiobiological analysis.

Anbumani S, Anchineyan P, Narayanasamy A, Palled SR, Sathisan S, Jayaraman P, Selvi M, Bilimagga RS.

ISRN Oncol. 2014 Jan 23;2014:125020. doi: 10.1155/2014/125020. eCollection 2014.

37.

blaKPC gene Detection in Clinical Isolates of Carbapenem Resistant Enterobacteriaceae in a Tertiary Care Hospital.

Shanmugam P, Meenakshisundaram J, Jayaraman P.

J Clin Diagn Res. 2013 Dec;7(12):2736-8. doi: 10.7860/JCDR/2013/7759.3747. Epub 2013 Dec 15.

38.

The pathway ontology - updates and applications.

Petri V, Jayaraman P, Tutaj M, Hayman GT, Smith JR, De Pons J, Laulederkind SJ, Lowry TF, Nigam R, Wang SJ, Shimoyama M, Dwinell MR, Munzenmaier DH, Worthey EA, Jacob HJ.

J Biomed Semantics. 2014 Feb 5;5(1):7. doi: 10.1186/2041-1480-5-7.

39.

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG.

Cancer Res. 2014 Feb 15;74(4):1067-78. doi: 10.1158/0008-5472.CAN-13-0588. Epub 2014 Jan 7.

40.

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.

Rothchild AC, Jayaraman P, Nunes-Alves C, Behar SM.

PLoS Pathog. 2014 Jan;10(1):e1003805. doi: 10.1371/journal.ppat.1003805. Epub 2014 Jan 2.

41.

PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin.

Kershaw RM, Siddiqui YH, Roberts D, Jayaraman PS, Gaston K.

Oncogene. 2014 Dec 4;33(49):5592-600. doi: 10.1038/onc.2013.496. Epub 2013 Nov 18.

PMID:
24240683
42.

Quantification of mesenchymal stem cell growth rates through secretory and excretory biomolecules in conditioned media via Fresnel reflection.

Ahmad H, Thambiratnam K, Zulkifli AZ, Lawrence A, Jasim AA, Kunasekaran W, Musa S, Gnanasegaran N, Vasanthan P, Jayaraman P, Kasim NH, Govindasamy V, Shahrir MS, Harun SW.

Sensors (Basel). 2013 Sep 30;13(10):13276-88. doi: 10.3390/s131013276.

43.

Rat Genome Database: a unique resource for rat, human, and mouse quantitative trait locus data.

Nigam R, Laulederkind SJ, Hayman GT, Smith JR, Wang SJ, Lowry TF, Petri V, De Pons J, Tutaj M, Liu W, Jayaraman P, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ.

Physiol Genomics. 2013 Sep 16;45(18):809-16. doi: 10.1152/physiolgenomics.00065.2013. Epub 2013 Jul 23.

44.

Novel phytochemical-antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR.

Jayaraman P, Sakharkar KR, Lim C, Siddiqi MI, Dhillon SK, Sakharkar MK.

Drug Des Devel Ther. 2013 Jun 17;7:449-75. doi: 10.2147/DDDT.S43964. Print 2013.

45.

T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation.

Jianjun Yang, Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, Chen SH, He JC, Ting AT, Zhou MM, Kuchroo VK, Morse HC 3rd, Ozato K, Sikora AG, Xiong H.

J Exp Med. 2013 Jul 1;210(7):1447-62.

46.

Hybrid-drug design targeting Pseudomonas aeruginosa dihydropteroate synthase and dihydrofolate reductase

Jayaraman P, Sakharkar KR, Daniel LC, Siddiqi MI, Dhillon SK, Sakharkar MK.

Front Biosci (Elite Ed). 2013 Jun 1;5:864-82.

PMID:
23747902
47.

Stem cells conditioned medium: a new approach to skin wound healing management.

Jayaraman P, Nathan P, Vasanthan P, Musa S, Govindasamy V.

Cell Biol Int. 2013 Oct;37(10):1122-8. doi: 10.1002/cbin.10138. Epub 2013 Jun 24.

PMID:
23716460
48.

InterMOD: integrated data and tools for the unification of model organism research.

Sullivan J, Karra K, Moxon SA, Vallejos A, Motenko H, Wong JD, Aleksic J, Balakrishnan R, Binkley G, Harris T, Hitz B, Jayaraman P, Lyne R, Neuhauser S, Pich C, Smith RN, Trinh Q, Cherry JM, Richardson J, Stein L, Twigger S, Westerfield M, Worthey E, Micklem G.

Sci Rep. 2013;3:1802. doi: 10.1038/srep01802. Erratum in: Sci Rep. 2013;3:3303.

49.

IL-1β promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.

Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson AC, Kuchroo VK, Remold HG, Behar SM.

J Immunol. 2013 Apr 15;190(8):4196-204. doi: 10.4049/jimmunol.1202688. Epub 2013 Mar 13.

50.

The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information.

Hayman GT, Jayaraman P, Petri V, Tutaj M, Liu W, De Pons J, Dwinell MR, Shimoyama M.

Hum Genomics. 2013 Feb 5;7:4. doi: 10.1186/1479-7364-7-4.

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