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Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses.

Tavassoly I, Hu Y, Zhao S, Mariottini C, Boran A, Chen Y, Li L, Tolentino RE, Jayaraman G, Goldfarb J, Gallo J, Iyengar R.

Mol Oncol. 2019 May 22. doi: 10.1002/1878-0261.12521. [Epub ahead of print]


Co-culture of Lactobacillus delbrueckii and engineered Lactococcus lactis enhances stoichiometric yield of D-lactic acid from whey permeate.

Sahoo TK, Jayaraman G.

Appl Microbiol Biotechnol. 2019 May 21. doi: 10.1007/s00253-019-09819-7. [Epub ahead of print]


Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.

Calizo RC, Bhattacharya S, van Hasselt JGC, Wei C, Wong JS, Wiener RJ, Ge X, Wong NJ, Lee JJ, Cuttitta CM, Jayaraman G, Au VH, Janssen W, Liu T, Li H, Salem F, Jaimes EA, Murphy B, Campbell KN, Azeloglu EU.

Nat Commun. 2019 May 3;10(1):2061. doi: 10.1038/s41467-019-09936-x.


Production of controlled molecular weight hyaluronic acid by glucostat strategy using recombinant Lactococcus lactis cultures.

Jeeva P, Shanmuga Doss S, Sundaram V, Jayaraman G.

Appl Microbiol Biotechnol. 2019 Jun;103(11):4363-4375. doi: 10.1007/s00253-019-09769-0. Epub 2019 Apr 9.


Patient characteristics, health seeking and delays among new sputum smear positive TB patients identified through active case finding when compared to passive case finding in India.

Shewade HD, Gupta V, Satyanarayana S, Pandey P, Bajpai UN, Tripathy JP, Kathirvel S, Pandurangan S, Mohanty S, Ghule VH, Sagili KD, Prasad BM, Nath S, Singh P, Singh K, Singh R, Jayaraman G, Rajeswaran P, Srivastava BK, Biswas M, Mallick G, Bera OP, Sahai KN, Murali L, Kamble S, Deshpande M, Kumar N, Kumar S, Jaisingh AJJ, Naqvi AJ, Verma P, Ansari MS, Mishra PC, Sumesh G, Barik S, Mathew V, Lohar MRS, Gaurkhede CS, Parate G, Bale SY, Koli I, Bharadwaj AK, Venkatraman G, Sathiyanarayanan K, Lal J, Sharma AK, Rao R, Kumar AMV, Chadha SS.

PLoS One. 2019 Mar 13;14(3):e0213345. doi: 10.1371/journal.pone.0213345. eCollection 2019.


Factors associated with sleep duration across life stages: results from the Canadian Health Measures Survey.

Chang VC, Chaput JP, Roberts KC, Jayaraman G, Do MT.

Health Promot Chronic Dis Prev Can. 2018 Nov;38(11):404-418. doi: 10.24095/hpcdp.38.11.02. English, French.


Evaluation of the anti-oxidant property and cytotoxic potential of the metabolites extracted from the bacterial isolates from mangrove Forest and saltern regions of South India.

Prathiba S, Jayaraman G.

Prep Biochem Biotechnol. 2018;48(8):750-758. doi: 10.1080/10826068.2018.1508038. Epub 2018 Oct 10.


Active case finding among marginalised and vulnerable populations reduces catastrophic costs due to tuberculosis diagnosis.

Shewade HD, Gupta V, Satyanarayana S, Kharate A, Sahai KN, Murali L, Kamble S, Deshpande M, Kumar N, Kumar S, Pandey P, Bajpai UN, Tripathy JP, Kathirvel S, Pandurangan S, Mohanty S, Ghule VH, Sagili KD, Prasad BM, Nath S, Singh P, Singh K, Singh R, Jayaraman G, Rajeswaran P, Srivastava BK, Biswas M, Mallick G, Bera OP, Jaisingh AJJ, Naqvi AJ, Verma P, Ansari MS, Mishra PC, Sumesh G, Barik S, Mathew V, Lohar MRS, Gaurkhede CS, Parate G, Bale SY, Koli I, Bharadwaj AK, Venkatraman G, Sathiyanarayanan K, Lal J, Sharma AK, Rao R, Kumar AMV, Chadha SS; as members of the Axshya SAMVAD study group.

Glob Health Action. 2018;11(1):1494897. doi: 10.1080/16549716.2018.1494897.


In vitro inhibition potential of mono-n-octyl phthalate on Mycobacterium tuberculosis H37Ra: Possibility of binding to mycobacterial PknB-An in silico approach.

Rajiniraja M, Sivaramakrishna A, Sabareesh V, Jayaraman G.

Biotechnol Appl Biochem. 2018 Nov;65(6):865-875. doi: 10.1002/bab.1685. Epub 2018 Aug 20.


At-a-glance - Traumatic brain injury management in Canada: changing patterns of care.

Rao DP, McFaull S, Thompson W, Jayaraman GC.

Health Promot Chronic Dis Prev Can. 2018 Mar;38(3):147-150. doi: 10.24095/hpcdp.38.3.05. English, French.


Real-time monitoring of hyaluronic acid fermentation by in situ transflectance spectroscopy.

Puvendran K, Anupama K, Jayaraman G.

Appl Microbiol Biotechnol. 2018 Mar;102(6):2659-2669. doi: 10.1007/s00253-018-8816-9. Epub 2018 Feb 13.


Cell shape information is transduced through tension-independent mechanisms.

Ron A, Azeloglu EU, Calizo RC, Hu M, Bhattacharya S, Chen Y, Jayaraman G, Lee S, Neves-Zaph SR, Li H, Gordon RE, He JC, Hone JC, Iyengar R.

Nat Commun. 2017 Dec 15;8(1):2145. doi: 10.1038/s41467-017-02218-4.


A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.

Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR.

Sci Rep. 2017 Nov 7;7(1):14626. doi: 10.1038/s41598-017-14892-x.


Implementation of broad screening with Ebola rapid diagnostic tests in Forécariah, Guinea.

Jean Louis F, Huang JY, Nebie YK, Koivogui L, Jayaraman G, Abiola N, Vansteelandt A, Worrel MC, Shang J, Murphy LB, Fitter DL, Marston BJ, Martel L.

Afr J Lab Med. 2017 Mar 31;6(1):484. doi: 10.4102/ajlm.v6i1.484. eCollection 2017.


The Physical Activity, Sedentary Behaviour and Sleep (PASS) Indicator Framework.

Roberts KC, Butler G, Branchard B, Rao DP, Otterman V, Thompson W, Jayaraman G.

Health Promot Chronic Dis Prev Can. 2017 Aug;37(8):252-256. doi: 10.24095/hpcdp.37.8.04. English, French. No abstract available.


Data collection using open access technology in multicentre operational research involving patient interviews.

Axshya SAMVAD Study Group, Shewade HD, Chadha SS, Gupta V, Tripathy JP, Satyanarayana S, Sagili K, Mohanty S, Bera OP, Pandey P, Rajeswaran P, Jayaraman G, Santhappan A, Bajpai UN, Mamatha AM, Maiser R, Naqvi AJ, Pandurangan S, Nath S, Ghule VH, Das A, Prasad BM, Biswas M, Singh G, Mallick G, Jeyakumar Jaisingh AJ, Rao R, Kumar AMV.

Public Health Action. 2017 Mar 21;7(1):74-77. doi: 10.5588/pha.15.0079.


Structural insights into the binding mode and conformational changes of BSA induced by bixin and crocin.

Mohan S, Hemachandran H, Sneha P, George Priya Doss C, Godwin Christopher J, Jayaraman G, Ramamoorthy S.

J Biomol Struct Dyn. 2018 Jun;36(8):2085-2098. doi: 10.1080/07391102.2017.1342565. Epub 2017 Jun 30.


Improving the accuracy of hyaluronic acid molecular weight estimation by conventional size exclusion chromatography.

Shanmuga Doss S, Bhatt NP, Jayaraman G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:255-261. doi: 10.1016/j.jchromb.2017.06.006. Epub 2017 Jun 8.


Measuring positive mental health in Canada: construct validation of the Mental Health Continuum-Short Form.

Orpana H, Vachon J, Dykxhoorn J, Jayaraman G.

Health Promot Chronic Dis Prev Can. 2017 Apr;37(4):123-130. doi: 10.24095/hpcdp.37.4.03. English, French.


Status report -- Childhood overweight and obesity in Canada: an integrative assessment.

Rao DP, Kropac E, Do MT, Roberts KC, Jayaraman GC.

Health Promot Chronic Dis Prev Can. 2017 Mar;37(3):87-93. English, French.


A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction.

Hu M, Azeloglu EU, Ron A, Tran-Ba KH, Calizo RC, Tavassoly I, Bhattacharya S, Jayaraman G, Chen Y, Rabinovich V, Iyengar R, Hone JC, He JC, Kaufman LJ.

Sci Rep. 2017 Mar 6;7:43934. doi: 10.1038/srep43934.


Childhood overweight and obesity trends in Canada.

Rao DP, Kropac E, Do MT, Roberts KC, Jayaraman GC.

Health Promot Chronic Dis Prev Can. 2016 Sep;36(9):194-8. English, French.


Common and Uncommon Anatomical Variants of Intrahepatic Bile Ducts in Magnetic Resonance Cholangiopancreatography and its Clinical Implication.

Sarawagi R, Sundar S, Raghuvanshi S, Gupta SK, Jayaraman G.

Pol J Radiol. 2016 May 26;81:250-5. doi: 10.12659/PJR.895827. eCollection 2016.


Quercetin-3-O-rhamnoside from Euphorbia hirta protects against snake Venom induced toxicity.

Gopi K, Anbarasu K, Renu K, Jayanthi S, Vishwanath BS, Jayaraman G.

Biochim Biophys Acta. 2016 Jul;1860(7):1528-40. doi: 10.1016/j.bbagen.2016.03.031. Epub 2016 Mar 28.


Notes from the Field: Baseline Assessment of the Use of Ebola Rapid Diagnostic Tests--Forécariah, Guinea, October-November 2015.

Huang JY, Louis FJ, Dixon MG, Sefu M, Kightlinger L, Martel LD, Jayaraman GC, Gueye AS.

MMWR Morb Mortal Wkly Rep. 2016 Apr 1;65(12):328-9. doi: 10.15585/mmwr.mm6512a4.


Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactis.

Kaur M, Jayaraman G.

Metab Eng Commun. 2016 Jan 22;3:15-23. doi: 10.1016/j.meteno.2016.01.003. eCollection 2016 Dec.


Monitoring positive mental health and its determinants in Canada: the development of the Positive Mental Health Surveillance Indicator Framework.

Orpana H, Vachon J, Dykxhoorn J, McRae L, Jayaraman G.

Health Promot Chronic Dis Prev Can. 2016 Jan;36(1):1-10. Review. English, French.


In Vitro Anti-Neuroblastoma Activity of Thymoquinone Against Neuro-2a Cells via Cell-cycle Arrest.

Paramasivam A, Raghunandhakumar S, Priyadharsini JV, Jayaraman G.

Asian Pac J Cancer Prev. 2015;16(18):8313-9.


Design of aqueous two-phase systems for purification of hyaluronic acid produced by metabolically engineered Lactococcus lactis.

Rajendran V, Puvendran K, Guru BR, Jayaraman G.

J Sep Sci. 2016 Feb;39(4):655-62. doi: 10.1002/jssc.201500907. Epub 2016 Jan 12.



Vickram AS, Kamini AR, Archana K, Jayaraman G, Venkat KS, Sridharan TB.

Cryo Letters. 2015 May-Jun;36(3):182-6.


Evidence Brief--Trends and projections of obesity among Canadians.

Bancej C, Jayabalasingham B, Wall RW, Rao DP, Do MT, de Groh M, Jayaraman GC.

Health Promot Chronic Dis Prev Can. 2015 Sep;35(7):109-12. English, French.


Prevalence and patterns of chronic disease multimorbidity and associated determinants in Canada.

Roberts KC, Rao DP, Bennett TL, Loukine L, Jayaraman GC.

Health Promot Chronic Dis Prev Can. 2015 Aug;35(6):87-94. English, French.


Canadian Public Health Laboratory Network national syphilis laboratory testing recommendations: INTRODUCTION.

Members of the Canadian Public Health Laboratory Network Syphilis Laboratory Task Group during authorship (co-chairs and membership in alphabetical order), Tsang RS, Morshed M, Allen V, Chernesky MA, Fonseca K, Garceau R, Jayaraman GC, Kadkhoda K, Lee BE, Levett PN, Radons SM, Serhir B, Singh AE, Wong T.

Can J Infect Dis Med Microbiol. 2015 Jan-Feb;26 Suppl A:4A-5A. No abstract available.


Canadian Public Health Laboratory Network laboratory guidelines for congenital syphilis and syphilis screening in pregnant women in Canada.

Singh AE, Levett PN, Fonseca K, Jayaraman GC, Lee BE.

Can J Infect Dis Med Microbiol. 2015 Jan-Feb;26 Suppl A:23A-8A.


Canadian Public Health Laboratory Network laboratory guidelines for the use of direct tests to detect syphilis in Canada.

Tsang RS, Morshed M, Chernesky MA, Jayaraman GC, Kadkhoda K.

Can J Infect Dis Med Microbiol. 2015 Jan-Feb;26 Suppl A:13A-7A.


Type-specific human papillomavirus infections and Pap test findings in Inuit and non-Inuit women in Nunavut, Canada.

Totten S, Severini A, Jayaraman GC, Faybush ST, Johnson G, Demers AA, Sobol I, Mao Y, Wong T.

Can Commun Dis Rep. 2015 Mar 5;41(3):43-51. eCollection 2015 Mar 5.


Protective effect of Euphorbia hirta and its components against snake venom induced lethality.

Gopi K, Renu K, Sannanaik Vishwanath B, Jayaraman G.

J Ethnopharmacol. 2015 May 13;165:180-90. doi: 10.1016/j.jep.2015.02.044. Epub 2015 Feb 26.


Biophysical characterization and molecular docking studies of imidazolium based polyelectrolytes-DNA complexes: role of hydrophobicity.

Manojkumar K, Prabhu Charan KT, Sivaramakrishna A, Jha PC, Khedkar VM, Siva R, Jayaraman G, Vijayakrishna K.

Biomacromolecules. 2015 Mar 9;16(3):894-903. doi: 10.1021/bm5018029. Epub 2015 Feb 18.


Biochemical changes induced by salt stress in halotolerant bacterial isolates are media dependent as well as species specific.

Joghee NN, Jayaraman G.

Prep Biochem Biotechnol. 2016;46(1):8-14. doi: 10.1080/10826068.2014.970689. Epub 2014 Oct 6.


Formulation and characterisation of antibody-conjugated soy protein nanoparticles--implications for neutralisation of snake venom with improved efficiency.

Renu K, Gopi K, Jayaraman G.

Appl Biochem Biotechnol. 2014 Dec;174(7):2557-70. doi: 10.1007/s12010-014-1207-5. Epub 2014 Sep 4.


Inhibition of Naja naja venom enzymes by the methanolic extract of Leucas aspera and its chemical profile by GC-MS.

Gopi K, Renu K, Jayaraman G.

Toxicol Rep. 2014 Aug 29;1:667-673. doi: 10.1016/j.toxrep.2014.08.012. eCollection 2014.


Chromosomal integration of hyaluronic acid synthesis (has) genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis.

Hmar RV, Prasad SB, Jayaraman G, Ramachandran KB.

Biotechnol J. 2014 Dec;9(12):1554-64. doi: 10.1002/biot.201400215. Epub 2014 Aug 21.


Monitoring chronic diseases in Canada: the Chronic Disease Indicator Framework.

Betancourt MT, Roberts KC, Bennett TL, Driscoll ER, Jayaraman G, Pelletier L.

Chronic Dis Inj Can. 2014 Spring;34 Suppl 1:1-30. Review. English, French.


Ratio of intracellular precursors concentration and their flux influences hyaluronic acid molecular weight in Streptococcus zooepidemicus and recombinant Lactococcus lactis.

Badle SS, Jayaraman G, Ramachandran KB.

Bioresour Technol. 2014 Jul;163:222-7. doi: 10.1016/j.biortech.2014.04.027. Epub 2014 Apr 18.


Metal ion activated lipase from halotolerant Bacillus sp. VITL8 displays broader operational range.

Balaji L, Jayaraman G.

Int J Biol Macromol. 2014 Jun;67:380-6. doi: 10.1016/j.ijbiomac.2014.03.050. Epub 2014 Apr 2.


Metabolomic characterization of halophilic bacterial isolates reveals strains synthesizing rare diaminoacids under salt stress.

Joghee NN, Jayaraman G.

Biochimie. 2014 Jul;102:102-11. doi: 10.1016/j.biochi.2014.02.015. Epub 2014 Mar 15.


Interconnected network motifs control podocyte morphology and kidney function.

Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R.

Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621.


Stability and detergent compatibility of a predominantly β-sheet serine protease from halotolerant B. aquimaris VITP4 strain.

Thaz CJ, Jayaraman G.

Appl Biochem Biotechnol. 2014 Jan;172(2):687-700. doi: 10.1007/s12010-013-0524-4. Epub 2013 Oct 10.


Demographic changes and trends in risk behaviours, HIV and other sexually transmitted infections among female sex workers in Bangalore, India involved in a focused HIV preventive intervention.

Jayaraman GC, Kumar S, Isac S, Javalkar P, Gowda PR, Raghunathan N, Gowda CS, Bhattacharjee P, Moses S, Blanchard JF.

Sex Transm Infect. 2013 Dec;89(8):635-41. doi: 10.1136/sextrans-2013-051203. Epub 2013 Sep 17.


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