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Items: 1 to 50 of 76

1.

Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort.

Latimer CS, Burke BT, Liachko NF, Currey HN, Kilgore MD, Gibbons LE, Henriksen J, Darvas M, Domoto-Reilly K, Jayadev S, Grabowski TJ, Crane PK, Larson EB, Kraemer BC, Bird TD, Keene CD.

Acta Neuropathol Commun. 2019 Jun 7;7(1):9. doi: 10.1186/s40478-019-0743-1.

2.

Alternative splicing in a presenilin 2 variant associated with Alzheimer disease.

Braggin JE, Bucks SA, Course MM, Smith CL, Sopher B, Osnis L, Shuey KD, Domoto-Reilly K, Caso C, Kinoshita C, Scherpelz KP, Cross C, Grabowski T, Nik SHM, Newman M, Garden GA, Leverenz JB, Tsuang D, Latimer C, Gonzalez-Cuyar LF, Keene CD, Morrison RS, Rhoads K, Wijsman EM, Dorschner MO, Lardelli M, Young JE, Valdmanis PN, Bird TD, Jayadev S.

Ann Clin Transl Neurol. 2019 Mar 10;6(4):762-777. doi: 10.1002/acn3.755. eCollection 2019 Apr.

3.

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies.

Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR Jr, Farlow MR, Salloway S, Snider BJ, Berman SB, Roberson ED, Brosch J, Jimenez-Velazques I, van Dyck CH, Galasko D, Yuan SH, Jayadev S, Honig LS, Gauthier S, Hsiung GR, Masellis M, Brooks WS, Fulham M, Clarnette R, Masters CL, Wallon D, Hannequin D, Dubois B, Pariente J, Sanchez-Valle R, Mummery C, Ringman JM, Bottlaender M, Klein G, Milosavljevic-Ristic S, McDade E, Xiong C, Morris JC, Bateman RJ, Benzinger TLS.

Alzheimers Dement (Amst). 2019 Feb 22;11:180-190. doi: 10.1016/j.dadm.2018.12.008. eCollection 2019 Dec.

4.

A Review of the Familial Alzheimer's Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1.

Jiang H, Jayadev S, Lardelli M, Newman M.

J Alzheimers Dis. 2018;66(4):1323-1339. doi: 10.3233/JAD-180656.

PMID:
30412492
5.

Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendinous xanthomatosis.

Duell PB, Salen G, Eichler FS, DeBarber AE, Connor SL, Casaday L, Jayadev S, Kisanuki Y, Lekprasert P, Malloy MJ, Ramdhani RA, Ziajka PE, Quinn JF, Su KG, Geller AS, Diffenderfer MR, Schaefer EJ.

J Clin Lipidol. 2018 Sep - Oct;12(5):1169-1178. doi: 10.1016/j.jacl.2018.06.008. Epub 2018 Jun 22.

6.

A Genetic Study of Psychosis in Huntington's Disease: Evidence for the Involvement of Glutamate Signaling Pathways.

Tsuang DW, Greenwood TA, Jayadev S, Davis M, Shutes-David A, Bird TD.

J Huntingtons Dis. 2018;7(1):51-59. doi: 10.3233/JHD-170277.

PMID:
29480208
7.

Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal.

Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H.

Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5.

8.

Quantitative cerebrovascular pathology in a community-based cohort of older adults.

Rane S, Koh N, Boord P, Madhyastha T, Askren MK, Jayadev S, Cholerton B, Larson E, Grabowski TJ.

Neurobiol Aging. 2018 May;65:77-85. doi: 10.1016/j.neurobiolaging.2018.01.006. Epub 2018 Jan 31.

9.

Novel pregnancy-triggered episodes of CAPOS syndrome.

Chang IJ, Adam MP, Jayadev S, Bird TD, Natarajan N, Glass IA.

Am J Med Genet A. 2018 Jan;176(1):235-240. doi: 10.1002/ajmg.a.38502. Epub 2017 Nov 1. Review.

10.

Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son.

Latimer CS, Flanagan ME, Cimino PJ, Jayadev S, Davis M, Hoffer ZS, Montine TJ, Gonzalez-Cuyar LF, Bird TD, Keene CD.

J Huntingtons Dis. 2017;6(4):337-348. doi: 10.3233/JHD-170261.

11.

Enhanced retinal responses in Huntington's disease patients.

Pearl JR, Heath LM, Bergey DE, Kelly JP, Smith C, Laurino MY, Weiss A, Price ND, LaSpada A, Bird TD, Jayadev S.

J Huntingtons Dis. 2017;6(3):237-247. doi: 10.3233/JHD-170255.

PMID:
28968243
12.

Psychosis in Spinocerebellar Ataxias: a Case Series and Study of Tyrosine Hydroxylase in Substantia Nigra.

Turk KW, Flanagan ME, Josephson S, Keene CD, Jayadev S, Bird TD.

Cerebellum. 2018 Apr;17(2):143-151. doi: 10.1007/s12311-017-0882-5.

13.

Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells.

Amos PJ, Fung S, Case A, Kifelew J, Osnis L, Smith CL, Green K, Naydenov A, Aloi M, Hubbard JJ, Ramakrishnan A, Garden GA, Jayadev S.

ASN Neuro. 2017 Jul-Aug;9(4):1759091417716610. doi: 10.1177/1759091417716610.

14.

Erratum to: Novel Report of Phosphoserine Phosphatase Deficiency in an Adult with Myeloneuropathy and Limb Contractures.

Byers HM, Bennett RL, Malouf EA, Weiss MD, Feng J, Scott CR, Jayadev S.

JIMD Rep. 2016;30:109. Epub 2016 Feb 19. No abstract available.

15.

Novel Report of Phosphoserine Phosphatase Deficiency in an Adult with Myeloneuropathy and Limb Contractures.

Byers HM, Bennett RL, Malouf EA, Weiss MD, Feng J, Scott CR, Jayadev S.

JIMD Rep. 2016;30:103-108. Epub 2015 Nov 21. Erratum in: JIMD Rep. 2016;30:109.

16.

R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study.

Korvatska O, Leverenz JB, Jayadev S, McMillan P, Kurtz I, Guo X, Rumbaugh M, Matsushita M, Girirajan S, Dorschner MO, Kiianitsa K, Yu CE, Brkanac Z, Garden GA, Raskind WH, Bird TD.

JAMA Neurol. 2015 Aug;72(8):920-7. doi: 10.1001/jamaneurol.2015.0979.

17.

Loss of endophilin-B1 exacerbates Alzheimer's disease pathology.

Wang DB, Kinoshita Y, Kinoshita C, Uo T, Sopher BL, Cudaback E, Keene CD, Bilousova T, Gylys K, Case A, Jayadev S, Wang HG, Garden GA, Morrison RS.

Brain. 2015 Jul;138(Pt 7):2005-19. doi: 10.1093/brain/awv128. Epub 2015 May 16.

18.

Giant coronary artery aneurysms involving all three coronary arteries.

Veenu J, Shetty GG, Adhyapak SM, Jayadev SM, Varghese K, Patil CB.

Indian Heart J. 2014 Nov-Dec;66(6):727-30. doi: 10.1016/j.ihj.2014.11.003. Epub 2014 Dec 17.

19.

The co-occurrence of Alzheimer's disease and Huntington's disease: a neuropathological study of 15 elderly Huntington's disease subjects.

Davis MY, Keene CD, Jayadev S, Bird T.

J Huntingtons Dis. 2014;3(2):209-17. doi: 10.3233/JHD-140111.

PMID:
25062863
20.

The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf.

Su W, Hopkins S, Nesser NK, Sopher B, Silvestroni A, Ammanuel S, Jayadev S, Möller T, Weinstein J, Garden GA.

J Immunol. 2014 Jan 1;192(1):358-66. doi: 10.4049/jimmunol.1301397. Epub 2013 Dec 6.

21.

Presenilin 2 influences miR146 level and activity in microglia.

Jayadev S, Case A, Alajajian B, Eastman AJ, Möller T, Garden GA.

J Neurochem. 2013 Dec;127(5):592-9. doi: 10.1111/jnc.12400. Epub 2013 Sep 30.

22.

Hereditary ataxias: overview.

Jayadev S, Bird TD.

Genet Med. 2013 Sep;15(9):673-83. doi: 10.1038/gim.2013.28. Epub 2013 Mar 28. Review.

PMID:
23538602
23.

Novel deletion of lysine 7 expands the clinical, histopathological and genetic spectrum of TPM2-related myopathies.

Davidson AE, Siddiqui FM, Lopez MA, Lunt P, Carlson HA, Moore BE, Love S, Born DE, Roper H, Majumdar A, Jayadev S, Underhill HR, Smith CO, von der Hagen M, Hubner A, Jardine P, Merrison A, Curtis E, Cullup T, Jungbluth H, Cox MO, Winder TL, Abdel Salam H, Li JZ, Moore SA, Dowling JJ.

Brain. 2013 Feb;136(Pt 2):508-21. doi: 10.1093/brain/aws344.

24.

Neurogenetics: Five new things.

Jayadev S, Smith CO, Bird TD.

Neurol Clin Pract. 2011 Dec;1(1):41-48. doi: 10.1212/CPJ.0b013e31823c0f5f. Erratum in: Neurol Clin Pract. 2012 Mar;2(1):4.

25.

Flies blown disease--oral myiasis.

Srivastava R, Devi P, Thimmarasa VB, Jayadev S.

Indian J Dent Res. 2011 Jul-Aug;22(4):615. doi: 10.4103/0970-9290.90328.

26.

Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity.

Cui Y, Huang Q, Auman JT, Knight B, Jin X, Blanchard KT, Chou J, Jayadev S, Paules RS.

Toxicol Sci. 2011 Nov;124(1):23-34. doi: 10.1093/toxsci/kfr217. Epub 2011 Aug 24.

27.

Sequential shrink photolithography for plastic microlens arrays.

Dyer D, Shreim S, Jayadev S, Lew V, Botvinick E, Khine M.

Appl Phys Lett. 2011 Jul 18;99(3):34102-341023. Epub 2011 Jul 19.

28.

Integration of absorption, distribution, metabolism, and elimination genotyping data into a population pharmacokinetic analysis of nevirapine.

Lehr T, Yuan J, Hall D, Zimdahl-Gelling H, Schaefer HG, Staab A, MacGregor TR, Jayadev S.

Pharmacogenet Genomics. 2011 Nov;21(11):721-30. doi: 10.1097/FPC.0b013e32834a522e.

PMID:
21860339
29.

Transcription factor p53 influences microglial activation phenotype.

Jayadev S, Nesser NK, Hopkins S, Myers SJ, Case A, Lee RJ, Seaburg LA, Uo T, Murphy SP, Morrison RS, Garden GA.

Glia. 2011 Oct;59(10):1402-13. doi: 10.1002/glia.21178. Epub 2011 May 19.

30.

Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent.

Yuan J, Guo S, Hall D, Cammett AM, Jayadev S, Distel M, Storfer S, Huang Z, Mootsikapun P, Ruxrungtham K, Podzamczer D, Haas DW; Nevirapine Toxicogenomics Study Team.

AIDS. 2011 Jun 19;25(10):1271-80. doi: 10.1097/QAD.0b013e32834779df.

31.

Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype.

Jayadev S, Nochlin D, Poorkaj P, Steinbart EJ, Mastrianni JA, Montine TJ, Ghetti B, Schellenberg GD, Bird TD, Leverenz JB.

Ann Neurol. 2011 Apr;69(4):712-20. doi: 10.1002/ana.22264. Epub 2011 Mar 17.

32.

Rule based classifier for the analysis of gene-gene and gene-environment interactions in genetic association studies.

Lehr T, Yuan J, Zeumer D, Jayadev S, Ritchie MD.

BioData Min. 2011 Mar 1;4:4. doi: 10.1186/1756-0381-4-4.

33.

Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release.

Jayadev S, Case A, Eastman AJ, Nguyen H, Pollak J, Wiley JC, Möller T, Morrison RS, Garden GA.

PLoS One. 2010 Dec 29;5(12):e15743. doi: 10.1371/journal.pone.0015743.

34.

Updates on the genetics of neurodegenerative disorders.

Tsuang DW, Jayadev S, Bird TD.

J Geriatr Psychiatry Neurol. 2010 Dec;23(4):211-2. doi: 10.1177/0891988710383575. Epub 2010 Oct 4.

35.

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium.

Dieterle F, Sistare F, Goodsaid F, Papaluca M, Ozer JS, Webb CP, Baer W, Senagore A, Schipper MJ, Vonderscher J, Sultana S, Gerhold DL, Phillips JA, Maurer G, Carl K, Laurie D, Harpur E, Sonee M, Ennulat D, Holder D, Andrews-Cleavenger D, Gu YZ, Thompson KL, Goering PL, Vidal JM, Abadie E, Maciulaitis R, Jacobson-Kram D, Defelice AF, Hausner EA, Blank M, Thompson A, Harlow P, Throckmorton D, Xiao S, Xu N, Taylor W, Vamvakas S, Flamion B, Lima BS, Kasper P, Pasanen M, Prasad K, Troth S, Bounous D, Robinson-Gravatt D, Betton G, Davis MA, Akunda J, McDuffie JE, Suter L, Obert L, Guffroy M, Pinches M, Jayadev S, Blomme EA, Beushausen SA, Barlow VG, Collins N, Waring J, Honor D, Snook S, Lee J, Rossi P, Walker E, Mattes W.

Nat Biotechnol. 2010 May;28(5):455-62. doi: 10.1038/nbt.1625. Epub 2010 May 10.

PMID:
20458315
36.

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

Jayadev S, Leverenz JB, Steinbart E, Stahl J, Klunk W, Yu CE, Bird TD.

Brain. 2010 Apr;133(Pt 4):1143-54. doi: 10.1093/brain/awq033.

37.

Host and viral factors influencing the pathogenesis of HIV-associated neurocognitive disorders.

Jayadev S, Garden GA.

J Neuroimmune Pharmacol. 2009 Jun;4(2):175-89. doi: 10.1007/s11481-009-9154-6. Epub 2009 Apr 17. Review.

38.

Conjugal Alzheimer disease: risk in children when both parents have Alzheimer disease.

Jayadev S, Steinbart EJ, Chi YY, Kukull WA, Schellenberg GD, Bird TD.

Arch Neurol. 2008 Mar;65(3):373-8. doi: 10.1001/archneurol.2007.61.

PMID:
18332250
39.

The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes.

Jayadev S, Yun B, Nguyen H, Yokoo H, Morrison RS, Garden GA.

J Neuroimmune Pharmacol. 2007 Dec;2(4):359-70. Epub 2007 Oct 20.

PMID:
18040854
40.

Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.

Auman JT, Chou J, Gerrish K, Huang Q, Jayadev S, Blanchard K, Paules RS.

Environ Health Perspect. 2007 Apr;115(4):572-8. Epub 2007 Jan 17.

41.

The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.

Belinsky GS, Parke AL, Huang Q, Blanchard K, Jayadev S, Stoll R, Rothe M, Achenie LE, Gupta RR, Wu GY, Rosenberg DW.

Toxicol Sci. 2007 Jun;97(2):582-94. Epub 2007 Mar 30.

PMID:
17400583
42.

Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones.

Srivastava BK, Solanki M, Mishra B, Soni R, Jayadev S, Valani D, Jain M, Patel PR.

Bioorg Med Chem Lett. 2007 Apr 1;17(7):1924-9. Epub 2007 Jan 24.

PMID:
17276057
43.

Potential applications and limitations of proteomics in the study of neurological disease.

Kinoshita Y, Uo T, Jayadev S, Garden GA, Conrads TP, Veenstra TD, Morrison RS.

Arch Neurol. 2006 Dec;63(12):1692-6. Review. No abstract available.

PMID:
17172608
44.

Cambodian founder effect for spinocerebellar ataxia type 3 (Machado-Joseph disease).

Jayadev S, Michelson S, Lipe H, Bird T.

J Neurol Sci. 2006 Dec 1;250(1-2):110-3. Epub 2006 Oct 5.

PMID:
17027034
45.

Gender differences in handedness and speech lateralization related to early neurologic insults.

Miller JW, Jayadev S, Dodrill CB, Ojemann GA.

Neurology. 2005 Dec 27;65(12):1974-5.

PMID:
16380623
46.

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion.

Doherty MJ, Watson NF, Jayadev S, Konchada RS, Hallam DK.

Neurology. 2005 Apr 26;64(8):1487; author reply 1487. No abstract available.

PMID:
15851762
47.

Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension.

Srinivasan J, Jayadev S, Kumaran D, Ahamed KF, Suresh B, Ramanathan M.

Indian J Exp Biol. 2005 Mar;43(3):241-6.

PMID:
15816410
48.

Clinical implications of splenium magnetic resonance imaging signal changes.

Doherty MJ, Jayadev S, Watson NF, Konchada RS, Hallam DK.

Arch Neurol. 2005 Mar;62(3):433-7.

PMID:
15767508
49.

HIV associated neurodegeneration requires p53 in neurons and microglia.

Garden GA, Guo W, Jayadev S, Tun C, Balcaitis S, Choi J, Montine TJ, Möller T, Morrison RS.

FASEB J. 2004 Jul;18(10):1141-3. Epub 2004 May 20.

PMID:
15155568
50.

Integration of clinical and gene expression endpoints to explore furan-mediated hepatotoxicity.

Hamadeh HK, Jayadev S, Gaillard ET, Huang Q, Stoll R, Blanchard K, Chou J, Tucker CJ, Collins J, Maronpot R, Bushel P, Afshari CA.

Mutat Res. 2004 May 18;549(1-2):169-83.

PMID:
15120969

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