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Items: 1 to 50 of 158

1.

Hepatic Bile Formation: Canalicular Osmolarity and Paracellular and Transcellular Water Flow.

Marinelli RA, Vore M, Javitt NB.

J Pharmacol Exp Ther. 2019 Dec;371(3):713-717. doi: 10.1124/jpet.119.261115. Epub 2019 Sep 30.

PMID:
31570498
2.

Fasting and postprandial serum bile acids after RYGB surgery.

Javitt NB.

Scand J Gastroenterol. 2018 Oct - Nov;53(10-11):1425-1426. doi: 10.1080/00365521.2018.1518483. Epub 2018 Oct 8. No abstract available.

PMID:
30295557
3.

Breast cancer and (25R)-26-hydroxycholesterol.

Javitt NB.

Steroids. 2015 Dec;104:61-4. doi: 10.1016/j.steroids.2015.08.012. Epub 2015 Aug 20. Review.

PMID:
26299212
4.

History of hepatic bile formation: old problems, new approaches.

Javitt NB.

Adv Physiol Educ. 2014 Dec;38(4):279-85. doi: 10.1152/advan.00076.2014.

6.

Alzheimer's disease: brain desmosterol levels.

Wisniewski T, Newman K, Javitt NB.

J Alzheimers Dis. 2013;33(3):881-8. doi: 10.3233/JAD-2012-121453.

7.

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.

Meljon A, Theofilopoulos S, Shackleton CH, Watson GL, Javitt NB, Knölker HJ, Saini R, Arenas E, Wang Y, Griffiths WJ.

J Lipid Res. 2012 Nov;53(11):2469-83. doi: 10.1194/jlr.D028233. Epub 2012 Aug 13.

8.

27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols.

Fakheri RJ, Javitt NB.

Steroids. 2012 May;77(6):575-7. doi: 10.1016/j.steroids.2012.02.006. Epub 2012 Feb 15. Review.

PMID:
22366074
9.

Autoregulation of cholesterol synthesis: physiologic and pathophysiologic consequences.

Fakheri RJ, Javitt NB.

Steroids. 2011 Feb;76(3):211-5. doi: 10.1016/j.steroids.2010.10.003. Epub 2010 Oct 15. Review.

PMID:
20951718
10.

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.

DuSell CD, Nelson ER, Wang X, Abdo J, Mödder UI, Umetani M, Gesty-Palmer D, Javitt NB, Khosla S, McDonnell DP.

Endocrinology. 2010 Aug;151(8):3675-85. doi: 10.1210/en.2010-0080. Epub 2010 May 25.

11.

The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration.

Javitt NB, Javitt JC.

Curr Opin Ophthalmol. 2009 May;20(3):151-7. doi: 10.1097/ICU.0b013e32832af468. Review.

PMID:
19390436
12.

Oxysterols: novel biologic roles for the 21st century.

Javitt NB.

Steroids. 2008 Feb;73(2):149-57. Epub 2007 Oct 22. Review.

PMID:
18068744
13.

Intrahepatic cholestasis of pregnancy: detection with urinary bile acid assays.

Huang WM, Seubert DE, Donnelly JG, Liu M, Javitt NB.

J Perinat Med. 2007;35(6):486-91.

PMID:
18052835
14.

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.

Umetani M, Domoto H, Gormley AK, Yuhanna IS, Cummins CL, Javitt NB, Korach KS, Shaul PW, Mangelsdorf DJ.

Nat Med. 2007 Oct;13(10):1185-92. Epub 2007 Sep 16.

PMID:
17873880
15.
16.

Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.

Crosignani A, Del Puppo M, Longo M, De Fabiani E, Caruso D, Zuin M, Podda M, Javitt NB, Kienle MG.

Clin Chim Acta. 2007 Jul;382(1-2):82-8. Epub 2007 Apr 12.

PMID:
17482152
17.

Oxysterols are substrates for cholesterol sulfotransferase.

Fuda H, Javitt NB, Mitamura K, Ikegawa S, Strott CA.

J Lipid Res. 2007 Jun;48(6):1343-52. Epub 2007 Mar 8.

18.

Expression and localization of sterol 27-hydroxylase (CYP27A1) in monkey retina.

Lee JW, Fuda H, Javitt NB, Strott CA, Rodriguez IR.

Exp Eye Res. 2006 Aug;83(2):465-9. Epub 2006 Mar 20.

19.
20.

A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.

Del Puppo M, Crosignani A, Longo M, Zuin M, Podda M, Galli G, De Fabiani E, Ciuffreda P, Santaniello E, Javitt NB, Kienle MG.

Clin Chim Acta. 2005 May;355(1-2):23-31.

PMID:
15820474
21.

Oxysteroids: a new class of steroids with autocrine and paracrine functions.

Javitt NB.

Trends Endocrinol Metab. 2004 Oct;15(8):393-7. Review.

PMID:
15380811
22.

Expression of cholesterol sulfotransferase (SULT2B1b) in human platelets.

Yanai H, Javitt NB, Higashi Y, Fuda H, Strott CA.

Circulation. 2004 Jan 6;109(1):92-6. Epub 2003 Dec 15.

PMID:
14676143
23.

Novel sterols synthesized via the CYP27A1 metabolic pathway.

Pikuleva I, Javitt NB.

Arch Biochem Biophys. 2003 Dec 1;420(1):35-9.

PMID:
14622972
24.

27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway.

Wassif CA, Yu J, Cui J, Porter FD, Javitt NB.

Steroids. 2003 Aug;68(6):497-502.

PMID:
12906934
25.

Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype.

Jabara S, Christenson LK, Wang CY, McAllister JM, Javitt NB, Dunaif A, Strauss JF 3rd.

J Clin Endocrinol Metab. 2003 Jan;88(1):484-92.

PMID:
12519894
27.
28.

Cholesterol, hydroxycholesterols, and bile acids.

Javitt NB.

Biochem Biophys Res Commun. 2002 Apr 19;292(5):1147-53. Review.

PMID:
11969205
30.

Immune complexes and IFN-gamma decrease cholesterol 27-hydroxylase in human arterial endothelium and macrophages.

Reiss AB, Awadallah NW, Malhotra S, Montesinos MC, Chan ES, Javitt NB, Cronstein BN.

J Lipid Res. 2001 Nov;42(11):1913-22.

31.
32.

Biologic role(s) of the 25(R),26-hydroxycholesterol metabolic pathway.

Javitt NB.

Biochim Biophys Acta. 2000 Dec 15;1529(1-3):136-41. Review.

PMID:
11111083
33.

Oxysterols: 27-hydroxycholesterol and its radiolabeled analog.

D'Ambra TE, Javitt NB, Lacy J, Srinivasan P, Warchol T.

Steroids. 2000 Jul;65(7):401-7.

PMID:
10899540
34.

Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1.

Wu Z, Martin KO, Javitt NB, Chiang JY.

J Lipid Res. 1999 Dec;40(12):2195-203.

35.

27-hydroxycholesterol: production rates in normal human subjects.

Duane WC, Javitt NB.

J Lipid Res. 1999 Jul;40(7):1194-9.

36.

Cholestasis of pregnancy: ursodeoxycholic acid therapy.

Javitt NB.

J Hepatol. 1998 Nov;29(5):827-8. No abstract available.

PMID:
9833923
37.

Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions.

Christenson LK, McAllister JM, Martin KO, Javitt NB, Osborne TF, Strauss JF 3rd.

J Biol Chem. 1998 Nov 13;273(46):30729-35.

38.

Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis.

Arnon R, Yoshimura T, Reiss A, Budai K, Lefkowitch JH, Javitt NB.

Gastroenterology. 1998 Nov;115(5):1223-8.

PMID:
9797378
39.

Cholic acid synthesis from 27-hydroxycholesterol in humans.

Javitt NB.

Gastroenterology. 1998 Aug;115(2):509. No abstract available.

PMID:
9758543
40.

Bile acid analysis in biological fluids: a novel approach.

Budai K, Javitt NB.

J Lipid Res. 1997 Sep;38(9):1906-12.

41.

Sterol 27-hydroxylase: expression in human arterial endothelium.

Reiss AB, Martin KO, Rojer DE, Iyer S, Grossi EA, Galloway AC, Javitt NB.

J Lipid Res. 1997 Jun;38(6):1254-60.

42.

7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis.

Martin KO, Reiss AB, Lathe R, Javitt NB.

J Lipid Res. 1997 May;38(5):1053-8.

43.
44.

Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity.

Sugawara T, Lin D, Holt JA, Martin KO, Javitt NB, Miller WL, Strauss JF 3rd.

Biochemistry. 1995 Oct 3;34(39):12506-12.

PMID:
7547998
45.

Cholesterol homeostasis: role of the LDL receptor.

Javitt NB.

FASEB J. 1995 Oct;9(13):1378-81. Review. No abstract available.

PMID:
7557029
46.
47.

Bile acid synthesis in HepG2 cells: effect of cyclosporin.

Levy J, Budai K, Javitt NB.

J Lipid Res. 1994 Oct;35(10):1795-800.

48.

Sterol 27-hydroxylase: high levels of activity in vascular endothelium.

Reiss AB, Martin KO, Javitt NB, Martin DW, Grossi EA, Galloway AC.

J Lipid Res. 1994 Jun;35(6):1026-30.

49.

Breast-gut connection: origin of chenodeoxycholic acid in breast cyst fluid.

Javitt NB, Budai K, Miller DG, Cahan AC, Raju U, Levitz M.

Lancet. 1994 Mar 12;343(8898):633-5. Erratum in: Lancet 1994 Apr 16;343(8903):986.

PMID:
7906811
50.

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