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Items: 17

1.

Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy.

Hernandez G, Luo T, Javed TA, Wen L, Kalwat MA, Vale K, Ammouri F, Husain SZ, Kliewer SA, Mangelsdorf DJ.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaay5186. doi: 10.1126/scitranslmed.aay5186.

PMID:
31915301
2.

Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling.

Mukherjee A, Ahmed N, Rose FT, Ahmad AN, Javed TA, Wen L, Bottino R, Xiao X, Kilberg MS, Husain SZ.

Cell Mol Gastroenterol Hepatol. 2020;9(1):1-13. doi: 10.1016/j.jcmgh.2019.08.003. Epub 2019 Aug 14.

3.

Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice.

Wen L, Javed TA, Yimlamai D, Mukherjee A, Xiao X, Husain SZ.

Gastroenterology. 2018 Oct;155(4):1250-1263.e5. doi: 10.1053/j.gastro.2018.06.036. Epub 2018 Jun 19.

4.

Pancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles.

Boggs K, Wang T, Orabi AI, Mukherjee A, Eisses JF, Sun T, Wen L, Javed TA, Esni F, Chen W, Husain SZ.

Sci Rep. 2018 Jan 23;8(1):1406. doi: 10.1038/s41598-018-19392-0.

5.

Pancreatitis-Induced Depletion of Syntaxin 2 Promotes Autophagy and Increases Basolateral Exocytosis.

Dolai S, Liang T, Orabi AI, Holmyard D, Xie L, Greitzer-Antes D, Kang Y, Xie H, Javed TA, Lam PP, Rubin DC, Thorn P, Gaisano HY.

Gastroenterology. 2018 May;154(6):1805-1821.e5. doi: 10.1053/j.gastro.2018.01.025. Epub 2018 Jan 31.

6.

Depletion of the membrane-fusion regulator Munc18c attenuates caerulein hyperstimulation-induced pancreatitis.

Dolai S, Liang T, Orabi AI, Xie L, Holmyard D, Javed TA, Fernandez NA, Xie H, Cattral MS, Thurmond DC, Thorn P, Gaisano HY.

J Biol Chem. 2018 Feb 16;293(7):2510-2522. doi: 10.1074/jbc.RA117.000792. Epub 2017 Dec 28.

7.

Targeted inhibition of pancreatic acinar cell calcineurin is a novel strategy to prevent post-ERCP pancreatitis.

Orabi AI, Wen L, Javed TA, Le T, Guo P, Sanker S, Ricks D, Boggs K, Eisses JF, Castro C, Xiao X, Prasadan K, Esni F, Gittes GK, Husain SZ.

Cell Mol Gastroenterol Hepatol. 2017 Jan;3(1):119-128. doi: 10.1016/j.jcmgh.2016.08.006.

8.

Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence.

Orabi AI, Sah S, Javed TA, Lemon KL, Good ML, Guo P, Xiao X, Prasadan K, Gittes GK, Jin S, Husain SZ.

J Biol Chem. 2016 Jan 15;291(3):1202. doi: 10.1074/jbc.A115.647933. No abstract available.

9.

Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.

Eisses JF, Criscimanna A, Dionise ZR, Orabi AI, Javed TA, Sarwar S, Jin S, Zhou L, Singh S, Poddar M, Davis AW, Tosun AB, Ozolek JA, Lowe ME, Monga SP, Rohde GK, Esni F, Husain SZ.

Am J Pathol. 2015 Dec;185(12):3304-15. doi: 10.1016/j.ajpath.2015.08.006. Epub 2015 Oct 23.

10.

Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin.

Jin S, Orabi AI, Le T, Javed TA, Sah S, Eisses JF, Bottino R, Molkentin JD, Husain SZ.

Gastroenterology. 2015 Sep;149(3):753-64.e11. doi: 10.1053/j.gastro.2015.05.004. Epub 2015 May 14.

11.

Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence.

Orabi AI, Sah S, Javed TA, Lemon KL, Good ML, Guo P, Xiao X, Prasadan K, Gittes GK, Jin S, Husain SZ.

J Biol Chem. 2015 May 1;290(18):11309-20. doi: 10.1074/jbc.M115.647933. Epub 2015 Mar 23. Erratum in: J Biol Chem. 2016 Jan 15;291(3):1202.

12.

Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release.

Orabi AI, Muili KA, Javed TA, Jin S, Jayaraman T, Lund FE, Husain SZ.

J Biol Chem. 2013 Sep 20;288(38):27128-37. doi: 10.1074/jbc.M113.494534. Epub 2013 Aug 12.

13.

Pancreatic acinar cell nuclear factor κB activation because of bile acid exposure is dependent on calcineurin.

Muili KA, Jin S, Orabi AI, Eisses JF, Javed TA, Le T, Bottino R, Jayaraman T, Husain SZ.

J Biol Chem. 2013 Jul 19;288(29):21065-73. doi: 10.1074/jbc.M113.471425. Epub 2013 Jun 6.

14.

Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.

Muili KA, Wang D, Orabi AI, Sarwar S, Luo Y, Javed TA, Eisses JF, Mahmood SM, Jin S, Singh VP, Ananthanaravanan M, Perides G, Williams JA, Molkentin JD, Husain SZ.

J Biol Chem. 2013 Jan 4;288(1):570-80. doi: 10.1074/jbc.M112.428896. Epub 2012 Nov 12.

15.

Health sector reforms programme in Punjab: a primary healthcare initiative.

Javed TA, Amin S.

Clin Med (Lond). 2007 Jan-Feb;7(1):19-22. Review.

16.

Primary squamous cell carcinoma of the prostate: a novel chemotherapy regimen.

Majeed F, Javed TA, Khan AU, Koerber RK.

J Urol. 2002 Aug;168(2):640. No abstract available.

PMID:
12131330
17.

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