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Items: 48

1.

PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization.

Mueller H, Lopez A, Tropberger P, Wildum S, Schmaler J, Pedersen L, Han X, Wang Y, Ottosen S, Yang S, Young JAT, Javanbakht H.

Hepatology. 2019 Apr;69(4):1398-1411. doi: 10.1002/hep.30329. Epub 2019 Mar 1.

PMID:
30365161
2.

Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action.

Han X, Zhou C, Jiang M, Wang Y, Wang J, Cheng Z, Wang M, Liu Y, Liang C, Wang J, Wang Z, Weikert R, Lv W, Xie J, Yu X, Zhou X, Luangsay S, Shen HC, Mayweg AV, Javanbakht H, Yang S.

J Med Chem. 2018 Dec 13;61(23):10619-10634. doi: 10.1021/acs.jmedchem.8b01245. Epub 2018 Oct 17.

PMID:
30286292
3.

Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo.

Javanbakht H, Mueller H, Walther J, Zhou X, Lopez A, Pattupara T, Blaising J, Pedersen L, Albæk N, Jackerott M, Shi T, Ploix C, Driessen W, Persson R, Ravn J, Young JAT, Ottosen S.

Mol Ther Nucleic Acids. 2018 Jun 1;11:441-454. doi: 10.1016/j.omtn.2018.02.005. Epub 2018 Feb 23.

4.

A novel orally available small molecule that inhibits hepatitis B virus expression.

Mueller H, Wildum S, Luangsay S, Walther J, Lopez A, Tropberger P, Ottaviani G, Lu W, Parrott NJ, Zhang JD, Schmucki R, Racek T, Hoflack JC, Kueng E, Point F, Zhou X, Steiner G, Lütgehetmann M, Rapp G, Volz T, Dandri M, Yang S, Young JAT, Javanbakht H.

J Hepatol. 2018 Mar;68(3):412-420. doi: 10.1016/j.jhep.2017.10.014. Epub 2017 Oct 25.

5.

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling.

Kratochwil NA, Meille C, Fowler S, Klammers F, Ekiciler A, Molitor B, Simon S, Walter I, McGinnis C, Walther J, Leonard B, Triyatni M, Javanbakht H, Funk C, Schuler F, Lavé T, Parrott NJ.

AAPS J. 2017 Mar;19(2):534-550. doi: 10.1208/s12248-016-0019-7. Epub 2017 Jan 3.

PMID:
28050713
6.

Hepatitis B Virus Surface Antigen Activates Myeloid Dendritic Cells via a Soluble CD14-Dependent Mechanism.

van Montfoort N, van der Aa E, van den Bosch A, Brouwers H, Vanwolleghem T, Janssen HLA, Javanbakht H, Buschow SI, Woltman AM.

J Virol. 2016 Jun 24;90(14):6187-6199. doi: 10.1128/JVI.02903-15. Print 2016 Jul 15.

7.

Early inhibition of hepatocyte innate responses by hepatitis B virus.

Luangsay S, Gruffaz M, Isorce N, Testoni B, Michelet M, Faure-Dupuy S, Maadadi S, Ait-Goughoulte M, Parent R, Rivoire M, Javanbakht H, Lucifora J, Durantel D, Zoulim F.

J Hepatol. 2015 Dec;63(6):1314-22. doi: 10.1016/j.jhep.2015.07.014. Epub 2015 Jul 26.

PMID:
26216533
8.

Expression and functionality of Toll- and RIG-like receptors in HepaRG cells.

Luangsay S, Ait-Goughoulte M, Michelet M, Floriot O, Bonnin M, Gruffaz M, Rivoire M, Fletcher S, Javanbakht H, Lucifora J, Zoulim F, Durantel D.

J Hepatol. 2015 Nov;63(5):1077-85. doi: 10.1016/j.jhep.2015.06.022. Epub 2015 Jul 3.

PMID:
26144659
9.

Phylogeny, Diversity, Distribution, and Host Specificity of Haemoproteus spp. (Apicomplexa: Haemosporida: Haemoproteidae) of Palaearctic Tortoises.

Javanbakht H, Kvičerová J, Dvořáková N, Mikulíček P, Sharifi M, Kautman M, Maršíková A, Široký P.

J Eukaryot Microbiol. 2015 Sep-Oct;62(5):670-8. doi: 10.1111/jeu.12227. Epub 2015 May 27.

PMID:
25939459
10.

Effects of administration of omega-3 fatty acids with or without vitamin E supplementation on adiponectin gene expression in PBMCs and serum adiponectin and adipocyte fatty acid-binding protein levels in male patients with CAD.

Ramezani A, Koohdani F, Djazayeri A, Nematipour E, Keshavarz SA, Saboor Yaraghi AA, Eshraghian MR, Yousefinejad A, Javanbakht H, Zarei M, Gholamhosseini S, Djalali M.

Anatol J Cardiol. 2015;15(12):981-9. doi: 10.5152/akd.2015.5849. Epub 2015 Apr 2.

11.

Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease.

Kennedy EM, Bassit LC, Mueller H, Kornepati AVR, Bogerd HP, Nie T, Chatterjee P, Javanbakht H, Schinazi RF, Cullen BR.

Virology. 2015 Feb;476:196-205. doi: 10.1016/j.virol.2014.12.001. Epub 2014 Dec 29.

12.

Hemolivia and hepatozoon: haemogregarines with tangled evolutionary relationships.

Kvičerová J, Hypša V, Dvořáková N, Mikulíček P, Jandzik D, Gardner MG, Javanbakht H, Tiar G, Siroký P.

Protist. 2014 Sep;165(5):688-700. doi: 10.1016/j.protis.2014.06.001. Epub 2014 Jul 2.

PMID:
25233121
13.

Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes.

White EA, Walther J, Javanbakht H, Howley PM.

J Virol. 2014 Aug;88(15):8201-12. doi: 10.1128/JVI.01197-14. Epub 2014 May 21.

14.

Intracellular effects of the Hepatitis C virus nucleoside polymerase inhibitor RO5855 (Mericitabine Parent) and Ribavirin in combination.

Ma H, Le Pogam S, Fletcher S, Hinojosa-Kirschenbaum F, Javanbakht H, Yan JM, Jiang WR, Inocencio N, Klumpp K, Nájera I.

Antimicrob Agents Chemother. 2014 May;58(5):2614-25. doi: 10.1128/AAC.02250-13. Epub 2014 Feb 18.

15.

Haemogregarines from western Palaearctic freshwater turtles (genera Emys, Mauremys) are conspecific with Haemogregarina stepanowi Danilewsky, 1885.

Dvořáková N, Kvičerová J, Papoušek I, Javanbakht H, Tiar G, Kami H, Široký P.

Parasitology. 2014 Apr;141(4):522-30. doi: 10.1017/S0031182013001820. Epub 2013 Nov 26.

PMID:
24476992
16.

The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques.

McGee K, Haim H, Korioth-Schmitz B, Espy N, Javanbakht H, Letvin N, Sodroski J.

J Virol. 2014 Jan;88(1):21-40. doi: 10.1128/JVI.01558-13. Epub 2013 Oct 16.

17.

Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture.

Flores O, Nakayama S, Whisnant AW, Javanbakht H, Cullen BR, Bloom DC.

J Virol. 2013 Jun;87(12):6589-603. doi: 10.1128/JVI.00504-13. Epub 2013 Mar 27.

18.

A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients.

Nguyen NM, Tran CN, Phung LK, Duong KT, Huynh Hle A, Farrar J, Nguyen QT, Tran HT, Nguyen CV, Merson L, Hoang LT, Hibberd ML, Aw PP, Wilm A, Nagarajan N, Nguyen DT, Pham MP, Nguyen TT, Javanbakht H, Klumpp K, Hammond J, Petric R, Wolbers M, Nguyen CT, Simmons CP.

J Infect Dis. 2013 May 1;207(9):1442-50. doi: 10.1093/infdis/jis470. Epub 2012 Jul 17.

19.

Oral and dental health status in patients with primary antibody deficiencies.

Meighani G, Aghamohammadi A, Javanbakht H, Abolhassani H, Nikayin S, Jafari SM, Ghandehari Motlagh M, Shamshiri AR, Rezaei N.

Iran J Allergy Asthma Immunol. 2011 Dec;10(4):289-93. doi: 010.04/ijaai.289293.

20.

Biochemical characterization of the inhibition of the dengue virus RNA polymerase by beta-d-2'-ethynyl-7-deaza-adenosine triphosphate.

Latour DR, Jekle A, Javanbakht H, Henningsen R, Gee P, Lee I, Tran P, Ren S, Kutach AK, Harris SF, Wang SM, Lok SJ, Shaw D, Li J, Heilek G, Klumpp K, Swinney DC, Deval J.

Antiviral Res. 2010 Aug;87(2):213-22. doi: 10.1016/j.antiviral.2010.05.003. Epub 2010 May 12.

PMID:
20470829
21.

In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor.

Javanbakht H, Ptak RG, Chow E, Yan JM, Russell JD, Mankowski MK, Hogan PA, Hogg JH, Vora H, Hang JQ, Li Y, Su G, Paul A, Cammack N, Klumpp K, Heilek G.

Antiviral Res. 2010 May;86(2):212-9. doi: 10.1016/j.antiviral.2010.02.323. Epub 2010 Feb 26.

PMID:
20219553
22.

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies.

Torimiro JN, Javanbakht H, Diaz-Griffero F, Kim J, Carr JK, Carrington M, Sawitzke J, Burke DS, Wolfe ND, Dean M, Sodroski J.

Virology. 2009 Aug 15;391(1):140-7. doi: 10.1016/j.virol.2009.05.038. Epub 2009 Jul 3.

23.

Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.

Sweeney ZK, Harris SF, Arora SF, Javanbakht H, Li Y, Fretland J, Davidson JP, Billedeau JR, Gleason SK, Hirschfeld D, Kennedy-Smith JJ, Mirzadegan T, Roetz R, Smith M, Sperry S, Suh JM, Wu J, Tsing S, Villaseñor AG, Paul A, Su G, Heilek G, Hang JQ, Zhou AS, Jernelius JA, Zhang FJ, Klumpp K.

J Med Chem. 2008 Dec 11;51(23):7449-58. doi: 10.1021/jm800527x.

PMID:
19007201
24.

Diphenyl ether non-nucleoside reverse transcriptase inhibitors with excellent potency against resistant mutant viruses and promising pharmacokinetic properties.

Sweeney ZK, Kennedy-Smith JJ, Wu J, Arora N, Billedeau JR, Davidson JP, Fretland J, Hang JQ, Heilek GM, Harris SF, Hirschfeld D, Inbar P, Javanbakht H, Jernelius JA, Jin Q, Li Y, Liang W, Roetz R, Sarma K, Smith M, Stefanidis D, Su G, Suh JM, Villaseñor AG, Welch M, Zhang FJ, Klumpp K.

ChemMedChem. 2009 Jan;4(1):88-99. doi: 10.1002/cmdc.200800262.

PMID:
19006142
25.

Variation in ectoparasite load reflects life history traits in the lesser mouse-eared bat Myotis blythii (Chiroptera: Vespertilionidae) in western Iran.

Sharifi M, Mozafari F, Taghinezhad N, Javanbakht H.

J Parasitol. 2008 Jun;94(3):622-5. doi: 10.1645/GE-1334.1.

PMID:
18605782
26.

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain.

Diaz-Griffero F, Kar A, Perron M, Xiang SH, Javanbakht H, Li X, Sodroski J.

J Virol. 2007 Oct;81(19):10362-78. Epub 2007 Jul 11.

27.

The ability of multimerized cyclophilin A to restrict retrovirus infection.

Javanbakht H, Diaz-Griffero F, Yuan W, Yeung DF, Li X, Song B, Sodroski J.

Virology. 2007 Oct 10;367(1):19-29. Epub 2007 Jun 15.

28.

Unique features of TRIM5alpha among closely related human TRIM family members.

Li X, Gold B, O'hUigin C, Diaz-Griffero F, Song B, Si Z, Li Y, Yuan W, Stremlau M, Mische C, Javanbakht H, Scally M, Winkler C, Dean M, Sodroski J.

Virology. 2007 Apr 10;360(2):419-33. Epub 2006 Dec 6.

29.

The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid.

Perron MJ, Stremlau M, Lee M, Javanbakht H, Song B, Sodroski J.

J Virol. 2007 Mar;81(5):2138-48. Epub 2006 Nov 29.

30.

Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.

Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, O'Brien SJ, Kirk GD, Detels R, Buchbinder S, Donfield S, Shulenin S, Song B, Perron MJ, Stremlau M, Sodroski J, Dean M, Winkler C.

Virology. 2006 Oct 10;354(1):15-27. Epub 2006 Aug 2.

31.

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding.

Javanbakht H, Yuan W, Yeung DF, Song B, Diaz-Griffero F, Li Y, Li X, Stremlau M, Sodroski J.

Virology. 2006 Sep 15;353(1):234-46. Epub 2006 Jun 30.

32.

Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1.

Stremlau M, Song B, Javanbakht H, Perron M, Sodroski J.

Virology. 2006 Jul 20;351(1):112-20. Epub 2006 Apr 27.

33.

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor.

Stremlau M, Perron M, Lee M, Li Y, Song B, Javanbakht H, Diaz-Griffero F, Anderson DJ, Sundquist WI, Sodroski J.

Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5514-9. Epub 2006 Mar 15.

34.

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

Diaz-Griffero F, Li X, Javanbakht H, Song B, Welikala S, Stremlau M, Sodroski J.

Virology. 2006 Jun 5;349(2):300-15. Epub 2006 Feb 10.

35.

Retroviral restriction factor TRIM5alpha is a trimer.

Mische CC, Javanbakht H, Song B, Diaz-Griffero F, Stremlau M, Strack B, Si Z, Sodroski J.

J Virol. 2005 Nov;79(22):14446-50.

36.

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha.

Javanbakht H, Diaz-Griffero F, Stremlau M, Si Z, Sodroski J.

J Biol Chem. 2005 Jul 22;280(29):26933-40. Epub 2005 May 15.

37.

The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.

Song B, Gold B, O'Huigin C, Javanbakht H, Li X, Stremlau M, Winkler C, Dean M, Sodroski J.

J Virol. 2005 May;79(10):6111-21.

38.

Retrovirus restriction by TRIM5alpha variants from Old World and New World primates.

Song B, Javanbakht H, Perron M, Park DH, Stremlau M, Sodroski J.

J Virol. 2005 Apr;79(7):3930-7.

39.

Cellular distribution of Lysyl-tRNA synthetase and its interaction with Gag during human immunodeficiency virus type 1 assembly.

Halwani R, Cen S, Javanbakht H, Saadatmand J, Kim S, Shiba K, Kleiman L.

J Virol. 2004 Jul;78(14):7553-64.

40.

The selective packaging and annealing of primer tRNALys3 in HIV-1.

Kleiman L, Halwani R, Javanbakht H.

Curr HIV Res. 2004 Apr;2(2):163-75. Review.

PMID:
15078180
41.
43.

The interaction between HIV-1 Gag and human lysyl-tRNA synthetase during viral assembly.

Javanbakht H, Halwani R, Cen S, Saadatmand J, Musier-Forsyth K, Gottlinger H, Kleiman L.

J Biol Chem. 2003 Jul 25;278(30):27644-51. Epub 2003 May 19.

44.

Retrovirus-specific packaging of aminoacyl-tRNA synthetases with cognate primer tRNAs.

Cen S, Javanbakht H, Kim S, Shiba K, Craven R, Rein A, Ewalt K, Schimmel P, Musier-Forsyth K, Kleiman L.

J Virol. 2002 Dec;76(24):13111-5.

46.

Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1.

Javanbakht H, Cen S, Musier-Forsyth K, Kleiman L.

J Biol Chem. 2002 May 17;277(20):17389-96. Epub 2002 Mar 7.

47.

Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1.

Cen S, Khorchid A, Javanbakht H, Gabor J, Stello T, Shiba K, Musier-Forsyth K, Kleiman L.

J Virol. 2001 Jun;75(11):5043-8.

48.

Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1.

Khorchid A, Javanbakht H, Wise S, Halwani R, Parniak MA, Wainberg MA, Kleiman L.

J Mol Biol. 2000 May 26;299(1):17-26.

PMID:
10860720

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