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Items: 7


Bioactive cell penetrating peptides and proteins in cancer: a bright future ahead.

Jauset T, Beaulieu ME.

Curr Opin Pharmacol. 2019 Apr 29;47:133-140. doi: 10.1016/j.coph.2019.03.014. [Epub ahead of print] Review.


Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.

Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L.

Sci Transl Med. 2019 Mar 20;11(484). pii: eaar5012. doi: 10.1126/scitranslmed.aar5012.


BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC.

Jauset T, Massó-Vallés D, Martínez-Martín S, Beaulieu ME, Foradada L, Fiorentino FP, Yokota J, Haendler B, Siegel S, Whitfield JR, Soucek L.

Oncotarget. 2018 Apr 10;9(27):18734-18746. doi: 10.18632/oncotarget.24648. eCollection 2018 Apr 10.


Ibrutinib repurposing: from B-cell malignancies to solid tumors.

Massó-Vallés D, Jauset T, Soucek L.

Oncoscience. 2016 Jun 10;3(5-6):147-8. doi: 10.18632/oncoscience.310. eCollection 2016. No abstract available.


Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation.

Fiorentino FP, Tokgün E, Solé-Sánchez S, Giampaolo S, Tokgün O, Jauset T, Kohno T, Perucho M, Soucek L, Yokota J.

Oncotarget. 2016 May 24;7(21):31014-28. doi: 10.18632/oncotarget.8826.


Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.

Massó-Vallés D, Jauset T, Serrano E, Sodir NM, Pedersen K, Affara NI, Whitfield JR, Beaulieu ME, Evan GI, Elias L, Arribas J, Soucek L.

Cancer Res. 2015 Apr 15;75(8):1675-81. doi: 10.1158/0008-5472.CAN-14-2852.


Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.

Annibali D, Whitfield JR, Favuzzi E, Jauset T, Serrano E, Cuartas I, Redondo-Campos S, Folch G, Gonzàlez-Juncà A, Sodir NM, Massó-Vallés D, Beaulieu ME, Swigart LB, Mc Gee MM, Somma MP, Nasi S, Seoane J, Evan GI, Soucek L.

Nat Commun. 2014 Aug 18;5:4632. doi: 10.1038/ncomms5632.

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