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Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunisation strategies for HCV.

Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P.

Hepatology. 2019 Aug 10. doi: 10.1002/hep.30894. [Epub ahead of print]


Cytomegalovirus distribution and evolution in hominines.

Murthy S, O'Brien K, Agbor A, Angedakin S, Arandjelovic M, Ayimisin EA, Bailey E, Bergl RA, Brazzola G, Dieguez P, Eno-Nku M, Eshuis H, Fruth B, Gillespie TR, Ginath Y, Gray M, Herbinger I, Jones S, Kehoe L, Kühl H, Kujirakwinja D, Lee K, Madinda NF, Mitamba G, Muhindo E, Nishuli R, Ormsby LJ, Petrzelkova KJ, Plumptre AJ, Robbins MM, Sommer V, Ter Heegde M, Todd A, Tokunda R, Wessling E, Jarvis MA, Leendertz FH, Ehlers B, Calvignac-Spencer S.

Virus Evol. 2019 Aug 1;5(2):vez015. doi: 10.1093/ve/vez015. eCollection 2019 Jul.


An Evaluation of a Low-Intensity Cognitive Behavioral Therapy mHealth-Supported Intervention to Reduce Loneliness in Older People.

Jarvis MA, Padmanabhanunni A, Chipps J.

Int J Environ Res Public Health. 2019 Apr 11;16(7). pii: E1305. doi: 10.3390/ijerph16071305.


Identification and Functional Characterization of a Novel Fc Gamma-Binding Glycoprotein in Rhesus Cytomegalovirus.

Kolb P, Sijmons S, McArdle MR, Taher H, Womack J, Hughes C, Ventura A, Jarvis MA, Stahl-Hennig C, Hansen S, Picker LJ, Malouli D, Hengel H, Früh K.

J Virol. 2019 Feb 5;93(4). pii: e02077-18. doi: 10.1128/JVI.02077-18. Print 2019 Feb 15.


Northern Ghana final-year nurses' attitudes towards nursing and remaining post qualification.

Abugri A, Jarvis MA.

Curationis. 2018 Jul 11;41(1):e1-e7. doi: 10.4102/curationis.v41i1.1832.


Mini-extracorporeal circulation technology, conventional bypass and prime displacement in isolated coronary and aortic valve surgery: a propensity-matched in-hospital and survival analysis.

Ariyaratnam P, Mclean LA, Cale A, Chaudhry MA, Vijayan A, Richards N, Jarvis MA, Haqzad Y, Ngaage D, Cowen ME, Loubani M.

Interact Cardiovasc Thorac Surg. 2018 Jul 1;27(1):13-19. doi: 10.1093/icvts/ivy035.


Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine.

Hansen SG, Zak DE, Xu G, Ford JC, Marshall EE, Malouli D, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Randall KT, Selseth AN, Rundstrom P, Herlache L, Lewis MS, Park H, Planer SL, Turner JM, Fischer M, Armstrong C, Zweig RC, Valvo J, Braun JM, Shankar S, Lu L, Sylwester AW, Legasse AW, Messerle M, Jarvis MA, Amon LM, Aderem A, Alter G, Laddy DJ, Stone M, Bonavia A, Evans TG, Axthelm MK, Früh K, Edlefsen PT, Picker LJ.

Nat Med. 2018 Feb;24(2):130-143. doi: 10.1038/nm.4473. Epub 2018 Jan 15.


Nutrient-extraction blender preparation reduces postprandial glucose responses from fruit juice consumption.

Redfern KM, Cammack VL, Sweet N, Preston LA; SoBHCS Student Team, Jarvis MA, Rees GA.

Nutr Diabetes. 2017 Oct 9;7(10):e288. doi: 10.1038/nutd.2017.36.


The effectiveness of e-Interventions on reducing social isolation in older persons: A systematic review of systematic reviews.

Chipps J, Jarvis MA, Ramlall S.

J Telemed Telecare. 2017 Dec;23(10):817-827. doi: 10.1177/1357633X17733773. Epub 2017 Sep 29. Review.


Social capital and mental well-being of older people residing in a residential care facility in Durban, South Africa.

Chipps J, Jarvis MA.

Aging Ment Health. 2016 Dec;20(12):1264-1270. Epub 2015 Nov 2.


Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.

Brown NG, VanderLinden R, Watson ER, Weissmann F, Ordureau A, Wu KP, Zhang W, Yu S, Mercredi PY, Harrison JS, Davidson IF, Qiao R, Lu Y, Dube P, Brunner MR, Grace CRR, Miller DJ, Haselbach D, Jarvis MA, Yamaguchi M, Yanishevski D, Petzold G, Sidhu SS, Kuhlman B, Kirschner MW, Harper JW, Peters JM, Stark H, Schulman BA.

Cell. 2016 Jun 2;165(6):1440-1453. doi: 10.1016/j.cell.2016.05.037.


Mechanism of APC/CCDC20 activation by mitotic phosphorylation.

Qiao R, Weissmann F, Yamaguchi M, Brown NG, VanderLinden R, Imre R, Jarvis MA, Brunner MR, Davidson IF, Litos G, Haselbach D, Mechtler K, Stark H, Schulman BA, Peters JM.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2570-8. doi: 10.1073/pnas.1604929113. Epub 2016 Apr 25.


Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection.

Marzi A, Murphy AA, Feldmann F, Parkins CJ, Haddock E, Hanley PW, Emery MJ, Engelmann F, Messaoudi I, Feldmann H, Jarvis MA.

Sci Rep. 2016 Feb 15;6:21674. doi: 10.1038/srep21674.


Self-disseminating vaccines for emerging infectious diseases.

Murphy AA, Redwood AJ, Jarvis MA.

Expert Rev Vaccines. 2016;15(1):31-9. doi: 10.1586/14760584.2016.1106942. Epub 2015 Nov 2. Review.


Genetic identification of cytomegaloviruses in a rural population of Côte d'Ivoire.

Anoh AE, Akoua-Koffi C, Couacy-Hymann E, Pauly M, Schubert G, Mossoun A, Weiss S, Leendertz SA, Jarvis MA, Leendertz FH, Ehlers B.

Virol J. 2015 Oct 5;12:155. doi: 10.1186/s12985-015-0394-1.


Measuring APC/C-Dependent Ubiquitylation In Vitro.

Jarvis MA, Brown NG, Watson ER, VanderLinden R, Schulman BA, Peters JM.

Methods Mol Biol. 2016;1342:287-303. doi: 10.1007/978-1-4939-2957-3_18.


Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo.

Spiess K, Jeppesen MG, Malmgaard-Clausen M, Krzywkowski K, Dulal K, Cheng T, Hjortø GM, Larsen O, Burg JS, Jarvis MA, Garcia KC, Zhu H, Kledal TN, Rosenkilde MM.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8427-32. doi: 10.1073/pnas.1509392112. Epub 2015 Jun 15.


A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose.

Tsuda Y, Parkins CJ, Caposio P, Feldmann F, Botto S, Ball S, Messaoudi I, Cicin-Sain L, Feldmann H, Jarvis MA.

Vaccine. 2015 May 5;33(19):2261-2266. doi: 10.1016/j.vaccine.2015.03.029. Epub 2015 Mar 25.


Discovery of a polyomavirus in European badgers (Meles meles) and the evolution of host range in the family Polyomaviridae.

Hill SC, Murphy AA, Cotten M, Palser AL, Benson P, Lesellier S, Gormley E, Richomme C, Grierson S, Bhuachalla DN, Chambers M, Kellam P, Boschiroli ML, Ehlers B, Jarvis MA, Pybus OG.

J Gen Virol. 2015 Jun;96(Pt 6):1411-22. doi: 10.1099/vir.0.000071. Epub 2015 Jan 27.


Identification and functional comparison of seven-transmembrane G-protein-coupled BILF1 receptors in recently discovered nonhuman primate lymphocryptoviruses.

Spiess K, Fares S, Sparre-Ulrich AH, Hilgenberg E, Jarvis MA, Ehlers B, Rosenkilde MM.

J Virol. 2015 Feb;89(4):2253-67. doi: 10.1128/JVI.02716-14. Epub 2014 Dec 10.


Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis.

MacManiman JD, Meuser A, Botto S, Smith PP, Liu F, Jarvis MA, Nelson JA, Caposio P.

MBio. 2014 Oct 28;5(6):e02035. doi: 10.1128/mBio.02035-14.


Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.

Brown NG, Watson ER, Weissmann F, Jarvis MA, VanderLinden R, Grace CRR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng JJ, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA.

Mol Cell. 2014 Oct 23;56(2):246-260. doi: 10.1016/j.molcel.2014.09.009. Epub 2014 Oct 9.


The effect of deep hypothermia on the human pulmonary circulation.

Ariyaratnam P, Loubani M, Cale AR, Chaudhry M, Cowen ME, Jarvis MA, Griffin S, Morice AH.

J Therm Biol. 2014 Feb;40:20-4. doi: 10.1016/j.jtherbio.2014.01.001. Epub 2014 Jan 13.


Complex aortic surgery in a regional center in the United Kingdom. Should the United Kingdom now adopt a United States-style supercenter model?

Ariyaratnam P, Loubani M, Griffin SC, Cowen ME, Vijayan A, Jarvis MA, Cale AR.

J Thorac Cardiovasc Surg. 2014 Oct;148(4):1428-1434.e1. doi: 10.1016/j.jtcvs.2014.01.009. Epub 2014 Jan 16.


Absence of frequent herpesvirus transmission in a nonhuman primate predator-prey system in the wild.

Murthy S, Couacy-Hymann E, Metzger S, Nowak K, De Nys H, Boesch C, Wittig R, Jarvis MA, Leendertz FH, Ehlers B.

J Virol. 2013 Oct;87(19):10651-9. doi: 10.1128/JVI.01104-13. Epub 2013 Jul 24.


Novel polyomaviruses of nonhuman primates: genetic and serological predictors for the existence of multiple unknown polyomaviruses within the human population.

Scuda N, Madinda NF, Akoua-Koffi C, Adjogoua EV, Wevers D, Hofmann J, Cameron KN, Leendertz SA, Couacy-Hymann E, Robbins M, Boesch C, Jarvis MA, Moens U, Mugisha L, Calvignac-Spencer S, Leendertz FH, Ehlers B.

PLoS Pathog. 2013;9(6):e1003429. doi: 10.1371/journal.ppat.1003429. Epub 2013 Jun 20.


Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.

Frye JJ, Brown NG, Petzold G, Watson ER, Grace CR, Nourse A, Jarvis MA, Kriwacki RW, Peters JM, Stark H, Schulman BA.

Nat Struct Mol Biol. 2013 Jul;20(7):827-35. doi: 10.1038/nsmb.2593. Epub 2013 May 26.


The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens.

Dekhtiarenko I, Jarvis MA, Ruzsics Z, Čičin-Šain L.

J Immunol. 2013 Apr 1;190(7):3399-409. doi: 10.4049/jimmunol.1203173. Epub 2013 Mar 4.


APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

Uzunova K, Dye BT, Schutz H, Ladurner R, Petzold G, Toyoda Y, Jarvis MA, Brown NG, Poser I, Novatchkova M, Mechtler K, Hyman AA, Stark H, Schulman BA, Peters JM.

Nat Struct Mol Biol. 2012 Nov;19(11):1116-23. doi: 10.1038/nsmb.2412. Epub 2012 Sep 24.


A cytomegalovirus-based vaccine expressing a single tumor-specific CD8+ T-cell epitope delays tumor growth in a murine model of prostate cancer.

Klyushnenkova EN, Kouiavskaia DV, Parkins CJ, Caposio P, Botto S, Alexander RB, Jarvis MA.

J Immunother. 2012 Jun;35(5):390-9. doi: 10.1097/CJI.0b013e3182585d50.


A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice.

Tierney R, Nakai T, Parkins CJ, Caposio P, Fairweather NF, Sesardic D, Jarvis MA.

Vaccine. 2012 Apr 26;30(20):3047-52. doi: 10.1016/j.vaccine.2012.02.043. Epub 2012 Mar 10.


Leadership in cardiac surgery: challenging the paradigms.

Jarvis MA.

Eur J Cardiothorac Surg. 2012 Mar;41(3):720-1; author reply 721-2. doi: 10.1093/ejcts/ezr072. Epub 2011 Nov 28. No abstract available.


A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus.

Tsuda Y, Caposio P, Parkins CJ, Botto S, Messaoudi I, Cicin-Sain L, Feldmann H, Jarvis MA.

PLoS Negl Trop Dis. 2011 Aug;5(8):e1275. doi: 10.1371/journal.pntd.0001275. Epub 2011 Aug 9.


Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine.

Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, Coyne-Johnson L, Whizin N, Oswald K, Shoemaker R, Swanson T, Legasse AW, Chiuchiolo MJ, Parks CL, Axthelm MK, Nelson JA, Jarvis MA, Piatak M Jr, Lifson JD, Picker LJ.

Nature. 2011 May 26;473(7348):523-7. doi: 10.1038/nature10003. Epub 2011 May 11.


Aorto-coronary vein graft 'Y' anastomosis made easy.

Jarvis MA.

Eur J Cardiothorac Surg. 2011 Oct;40(4):1027-8. doi: 10.1016/j.ejcts.2011.01.012. Epub 2011 Feb 24.


Molecular basis of persistence and latency.

Jarvis MA, Nelson JA.

In: Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B, Whitley R, Yamanishi K, editors. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007. Chapter 42.


Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.

Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Früh K.

Science. 2010 Apr 2;328(5974):102-6. doi: 10.1126/science.1185350.


A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells.

Wille PT, Knoche AJ, Nelson JA, Jarvis MA, Johnson DC.

J Virol. 2010 Mar;84(5):2585-96. doi: 10.1128/JVI.02249-09. Epub 2009 Dec 23.


A novel Cre recombinase imaging system for tracking lymphotropic virus infection in vivo.

Dutia BM, Reid SJ, Drummond DD, Ligertwood Y, Bennet I, Rietberg W, Silvia O, Jarvis MA, Nash AA.

PLoS One. 2009 Aug 4;4(8):e6492. doi: 10.1371/journal.pone.0006492.


Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge.

Hansen SG, Vieville C, Whizin N, Coyne-Johnson L, Siess DC, Drummond DD, Legasse AW, Axthelm MK, Oswald K, Trubey CM, Piatak M Jr, Lifson JD, Nelson JA, Jarvis MA, Picker LJ.

Nat Med. 2009 Mar;15(3):293-9. doi: 10.1038/nm.1935. Epub 2009 Feb 15. Erratum in: Nat Med. 2009 Apr;15(4):462. Nat Med. 2011 Dec;17(12):1692.


Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.

Ryckman BJ, Rainish BL, Chase MC, Borton JA, Nelson JA, Jarvis MA, Johnson DC.

J Virol. 2008 Jan;82(1):60-70. Epub 2007 Oct 17.


Human cytomegalovirus tropism for endothelial cells: not all endothelial cells are created equal.

Jarvis MA, Nelson JA.

J Virol. 2007 Mar;81(5):2095-101. Epub 2006 Sep 6. Review. No abstract available.


Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.

Hegde NR, Dunn C, Lewinsohn DM, Jarvis MA, Nelson JA, Johnson DC.

J Exp Med. 2005 Oct 17;202(8):1109-19. Epub 2005 Oct 10.


Antigenic domain 1 is required for oligomerization of human cytomegalovirus glycoprotein B.

Britt WJ, Jarvis MA, Drummond DD, Mach M.

J Virol. 2005 Apr;79(7):4066-79.


A cyclooxygenase-2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism.

Rue CA, Jarvis MA, Knoche AJ, Meyers HL, DeFilippis VR, Hansen SG, Wagner M, Früh K, Anders DG, Wong SW, Barry PA, Nelson JA.

J Virol. 2004 Nov;78(22):12529-36.


Coding potential of laboratory and clinical strains of human cytomegalovirus.

Murphy E, Yu D, Grimwood J, Schmutz J, Dickson M, Jarvis MA, Hahn G, Nelson JA, Myers RM, Shenk TE.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14976-81. Epub 2003 Dec 1.


A functional genomics approach to Kaposi's sarcoma.

Moses AV, Jarvis MA, Raggo C, Bell YC, Ruhl R, Luukkonen BG, Griffith DJ, Wait CL, Druker BJ, Heinrich MC, Nelson JA, Fruh K.

Ann N Y Acad Sci. 2002 Dec;975:180-91.


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