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Items: 36


A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.

Cassotta A, Mikol V, Bertrand T, Pouzieux S, Le Parc J, Ferrari P, Dumas J, Auer M, Deisenhammer F, Gastaldi M, Franciotta D, Silacci-Fregni C, Fernandez Rodriguez B, Giacchetto-Sasselli I, Foglierini M, Jarrossay D, Geiger R, Sallusto F, Lanzavecchia A, Piccoli L.

Nat Med. 2019 Sep;25(9):1402-1407. doi: 10.1038/s41591-019-0568-2. Epub 2019 Sep 9.


Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells.

Aschenbrenner D, Foglierini M, Jarrossay D, Hu D, Weiner HL, Kuchroo VK, Lanzavecchia A, Notarbartolo S, Sallusto F.

Nat Immunol. 2019 Jan;20(1):109. doi: 10.1038/s41590-018-0264-2.


T cells in patients with narcolepsy target self-antigens of hypocretin neurons.

Latorre D, Kallweit U, Armentani E, Foglierini M, Mele F, Cassotta A, Jovic S, Jarrossay D, Mathis J, Zellini F, Becher B, Lanzavecchia A, Khatami R, Manconi M, Tafti M, Bassetti CL, Sallusto F.

Nature. 2018 Oct;562(7725):63-68. doi: 10.1038/s41586-018-0540-1. Epub 2018 Sep 19.


An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells.

Aschenbrenner D, Foglierini M, Jarrossay D, Hu D, Weiner HL, Kuchroo VK, Lanzavecchia A, Notarbartolo S, Sallusto F.

Nat Immunol. 2018 Oct;19(10):1126-1136. doi: 10.1038/s41590-018-0200-5. Epub 2018 Sep 10. Erratum in: Nat Immunol. 2019 Jan;20(1):109.


Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with protection from vertical transmission.

Mele F, Fornara C, Jarrossay D, Furione M, Arossa A, Spinillo A, Lanzavecchia A, Gerna G, Sallusto F, Lilleri D.

PLoS One. 2017 Nov 7;12(11):e0187731. doi: 10.1371/journal.pone.0187731. eCollection 2017.


Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.

Pieper K, Tan J, Piccoli L, Foglierini M, Barbieri S, Chen Y, Silacci-Fregni C, Wolf T, Jarrossay D, Anderle M, Abdi A, Ndungu FM, Doumbo OK, Traore B, Tran TM, Jongo S, Zenklusen I, Crompton PD, Daubenberger C, Bull PC, Sallusto F, Lanzavecchia A.

Nature. 2017 Aug 31;548(7669):597-601. doi: 10.1038/nature23670. Epub 2017 Aug 23.


Social network architecture of human immune cells unveiled by quantitative proteomics.

Rieckmann JC, Geiger R, Hornburg D, Wolf T, Kveler K, Jarrossay D, Sallusto F, Shen-Orr SS, Lanzavecchia A, Mann M, Meissner F.

Nat Immunol. 2017 May;18(5):583-593. doi: 10.1038/ni.3693. Epub 2017 Mar 6.


Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines.

Dietrich D, Martin P, Flacher V, Sun Y, Jarrossay D, Brembilla N, Mueller C, Arnett HA, Palmer G, Towne J, Gabay C.

Cytokine. 2016 Aug;84:88-98. doi: 10.1016/j.cyto.2016.05.012. Epub 2016 May 31.


A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.

Tan J, Pieper K, Piccoli L, Abdi A, Perez MF, Geiger R, Tully CM, Jarrossay D, Maina Ndungu F, Wambua J, Bejon P, Fregni CS, Fernandez-Rodriguez B, Barbieri S, Bianchi S, Marsh K, Thathy V, Corti D, Sallusto F, Bull P, Lanzavecchia A.

Nature. 2016 Jan 7;529(7584):105-109. doi: 10.1038/nature16450. Epub 2015 Dec 23.


Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity.

Toso A, Revandkar A, Di Mitri D, Guccini I, Proietti M, Sarti M, Pinton S, Zhang J, Kalathur M, Civenni G, Jarrossay D, Montani E, Marini C, Garcia-Escudero R, Scanziani E, Grassi F, Pandolfi PP, Catapano CV, Alimonti A.

Cell Rep. 2014 Oct 9;9(1):75-89. doi: 10.1016/j.celrep.2014.08.044. Epub 2014 Sep 25.


The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.

Engen SA, Valen Rukke H, Becattini S, Jarrossay D, Blix IJ, Petersen FC, Sallusto F, Schenck K.

PLoS One. 2014 Aug 13;9(8):e104306. doi: 10.1371/journal.pone.0104306. eCollection 2014.


CXCR7 influences the migration of B cells during maturation.

Humpert ML, Pinto D, Jarrossay D, Thelen M.

Eur J Immunol. 2014 Mar;44(3):694-705. doi: 10.1002/eji.201343907. Epub 2014 Feb 19.


Immune response: steroids drive dendritic cells.

Jarrossay D, Thelen M.

Nat Immunol. 2013 May;14(5):424-6. doi: 10.1038/ni.2589. No abstract available.


A functional BCR in human IgA and IgM plasma cells.

Pinto D, Montani E, Bolli M, Garavaglia G, Sallusto F, Lanzavecchia A, Jarrossay D.

Blood. 2013 May 16;121(20):4110-4. doi: 10.1182/blood-2012-09-459289. Epub 2013 Apr 2.


Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F.

Nature. 2012 Apr 26;484(7395):514-8. doi: 10.1038/nature10957.


A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.

Corti D, Voss J, Gamblin SJ, Codoni G, Macagno A, Jarrossay D, Vachieri SG, Pinna D, Minola A, Vanzetta F, Silacci C, Fernandez-Rodriguez BM, Agatic G, Bianchi S, Giacchetto-Sasselli I, Calder L, Sallusto F, Collins P, Haire LF, Temperton N, Langedijk JP, Skehel JJ, Lanzavecchia A.

Science. 2011 Aug 12;333(6044):850-6. doi: 10.1126/science.1205669. Epub 2011 Jul 28.


CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.

Chevalier N, Jarrossay D, Ho E, Avery DT, Ma CS, Yu D, Sallusto F, Tangye SG, Mackay CR.

J Immunol. 2011 May 15;186(10):5556-68. doi: 10.4049/jimmunol.1002828. Epub 2011 Apr 6.


CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function.

Rivino L, Gruarin P, Häringer B, Steinfelder S, Lozza L, Steckel B, Weick A, Sugliano E, Jarrossay D, Kühl AA, Loddenkemper C, Abrignani S, Sallusto F, Lanzavecchia A, Geginat J.

J Exp Med. 2010 Mar 15;207(3):565-77. doi: 10.1084/jem.20091021. Epub 2010 Mar 1.


Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.

Corti D, Langedijk JP, Hinz A, Seaman MS, Vanzetta F, Fernandez-Rodriguez BM, Silacci C, Pinna D, Jarrossay D, Balla-Jhagjhoorsingh S, Willems B, Zekveld MJ, Dreja H, O'Sullivan E, Pade C, Orkin C, Jeffs SA, Montefiori DC, Davis D, Weissenhorn W, McKnight A, Heeney JL, Sallusto F, Sattentau QJ, Weiss RA, Lanzavecchia A.

PLoS One. 2010 Jan 20;5(1):e8805. doi: 10.1371/journal.pone.0008805.


Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F.

Nat Immunol. 2009 Aug;10(8):857-63. doi: 10.1038/ni.1767. Epub 2009 Jul 5.


Clonal dissection of the human memory B-cell repertoire following infection and vaccination.

Pinna D, Corti D, Jarrossay D, Sallusto F, Lanzavecchia A.

Eur J Immunol. 2009 May;39(5):1260-70. doi: 10.1002/eji.200839129.


Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint.

Manzo A, Vitolo B, Humby F, Caporali R, Jarrossay D, Dell'accio F, Ciardelli L, Uguccioni M, Montecucco C, Pitzalis C.

Arthritis Rheum. 2008 Nov;58(11):3377-87. doi: 10.1002/art.23966.


The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells.

Lozza L, Rivino L, Guarda G, Jarrossay D, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A, Geginat J.

Eur J Immunol. 2008 Jan;38(1):30-9.


Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow.

Onai N, Obata-Onai A, Schmid MA, Ohteki T, Jarrossay D, Manz MG.

Nat Immunol. 2007 Nov;8(11):1207-16. Epub 2007 Oct 7.


Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells.

Acosta-Rodriguez EV, Rivino L, Geginat J, Jarrossay D, Gattorno M, Lanzavecchia A, Sallusto F, Napolitani G.

Nat Immunol. 2007 Jun;8(6):639-46. Epub 2007 May 7.


Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA.

Barfod L, Bernasconi NL, Dahlbäck M, Jarrossay D, Andersen PH, Salanti A, Ofori MF, Turner L, Resende M, Nielsen MA, Theander TG, Sallusto F, Lanzavecchia A, Hviid L.

Mol Microbiol. 2007 Jan;63(2):335-47. Epub 2006 Dec 14.


Distinct expression pattern of IFN-alpha and TNF-alpha in juvenile idiopathic arthritis synovial tissue.

Gattorno M, Chicha L, Gregorio A, Ferlito F, Rossi F, Jarrossay D, Lanzavecchia A, Martini A, Manz MG.

Rheumatology (Oxford). 2007 Apr;46(4):657-65. Epub 2006 Nov 3.


Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cells.

Pantano S, Jarrossay D, Saccani S, Bosisio D, Natoli G.

Exp Cell Res. 2006 May 1;312(8):1312-22. Epub 2006 Feb 7.


Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA.

Scheel B, Teufel R, Probst J, Carralot JP, Geginat J, Radsak M, Jarrossay D, Wagner H, Jung G, Rammensee HG, Hoerr I, Pascolo S.

Eur J Immunol. 2005 May;35(5):1557-66.


Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells.

Rivino L, Messi M, Jarrossay D, Lanzavecchia A, Sallusto F, Geginat J.

J Exp Med. 2004 Sep 20;200(6):725-35.


Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice.

Feau S, Facchinetti V, Granucci F, Citterio S, Jarrossay D, Seresini S, Protti MP, Lanzavecchia A, Ricciardi-Castagnoli P.

Blood. 2005 Jan 15;105(2):697-702. Epub 2004 Sep 7.


Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells.

Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A.

Eur J Immunol. 2001 Nov;31(11):3388-93.


Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment.

Mohty M, Jarrossay D, Lafage-Pochitaloff M, Zandotti C, Brière F, de Lamballeri XN, Isnardon D, Sainty D, Olive D, Gaugler B.

Blood. 2001 Dec 15;98(13):3750-6.


The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors.

Bühring HJ, Simmons PJ, Pudney M, Müller R, Jarrossay D, van Agthoven A, Willheim M, Brugger W, Valent P, Kanz L.

Blood. 1999 Oct 1;94(7):2343-56.


Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon.

Cella M, Jarrossay D, Facchetti F, Alebardi O, Nakajima H, Lanzavecchia A, Colonna M.

Nat Med. 1999 Aug;5(8):919-23.


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