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Items: 19


AMPLIFY: a randomized, Phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to-very severe symptomatic COPD.

Sethi S, Kerwin E, Watz H, Ferguson GT, Mroz RM, Segarra R, Molins E, Jarreta D, Garcia Gil E.

Int J Chron Obstruct Pulmon Dis. 2019 Mar 22;14:667-682. doi: 10.2147/COPD.S189138. eCollection 2019.


The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study.

Smith JA, McGarvey L, Morice AH, Birring SS, Wedzicha JA, Notari M, Zapata A, Segarra R, Seoane B, Jarreta D.

Am J Respir Crit Care Med. 2019 Sep 1;200(5):642-645. doi: 10.1164/rccm.201901-0048LE. No abstract available.


Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT.

D'Urzo AD, Singh D, Donohue JF, Kerwin EM, Ribera A, Molins E, Chuecos F, Jarreta D, Gil EG.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 26;14:479-491. doi: 10.2147/COPD.S185502. eCollection 2019.


ACTIVATE: the effect of aclidinium/formoterol on hyperinflation, exercise capacity, and physical activity in patients with COPD.

Watz H, Troosters T, Beeh KM, Garcia-Aymerich J, Paggiaro P, Molins E, Notari M, Zapata A, Jarreta D, Garcia Gil E.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 24;12:2545-2558. doi: 10.2147/COPD.S143488. eCollection 2017.


Physical activity patterns and clusters in 1001 patients with COPD.

Mesquita R, Spina G, Pitta F, Donaire-Gonzalez D, Deering BM, Patel MS, Mitchell KE, Alison J, van Gestel AJ, Zogg S, Gagnon P, Abascal-Bolado B, Vagaggini B, Garcia-Aymerich J, Jenkins SC, Romme EA, Kon SS, Albert PS, Waschki B, Shrikrishna D, Singh SJ, Hopkinson NS, Miedinger D, Benzo RP, Maltais F, Paggiaro P, McKeough ZJ, Polkey MI, Hill K, Man WD, Clarenbach CF, Hernandes NA, Savi D, Wootton S, Furlanetto KC, Cindy Ng LW, Vaes AW, Jenkins C, Eastwood PR, Jarreta D, Kirsten A, Brooks D, Hillman DR, Sant'Anna T, Meijer K, Dürr S, Rutten EP, Kohler M, Probst VS, Tal-Singer R, Gil EG, den Brinker AC, Leuppi JD, Calverley PM, Smeenk FW, Costello RW, Gramm M, Goldstein R, Groenen MT, Magnussen H, Wouters EF, ZuWallack RL, Amft O, Watz H, Spruit MA.

Chron Respir Dis. 2017 Aug;14(3):256-269. doi: 10.1177/1479972316687207. Epub 2017 Feb 24.


Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity.

Spina G, Spruit MA, Alison J, Benzo RP, Calverley PMA, Clarenbach CF, Costello RW, Donaire-Gonzalez D, Dürr S, Garcia-Aymerich J, van Gestel AJR, Gramm M, Hernandes NA, Hill K, Hopkinson NS, Jarreta D, Kohler M, Kirsten AM, Leuppi JD, Magnussen H, Maltais F, Man WD, McKeough ZJ, Mesquita R, Miedinger D, Pitta F, Singh SJ, Smeenk FWJM, Tal-Singer R, Vagaggini B, Waschki B, Watz H, Wouters EFM, Zogg S, den Brinker AC.

Thorax. 2017 Aug;72(8):694-701. doi: 10.1136/thoraxjnl-2016-208900. Epub 2017 Jan 12.


Effect of aclidinium bromide on cough and sputum symptoms in moderate-to-severe COPD in three phase III trials.

McGarvey L, Morice AH, Smith JA, Birring SS, Chuecos F, Seoane B, Jarreta D.

BMJ Open Respir Res. 2016 Dec 8;3(1):e000148. doi: 10.1136/bmjresp-2016-000148. eCollection 2016.


Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial.

Beeh KM, Watz H, Puente-Maestu L, de Teresa L, Jarreta D, Caracta C, Garcia Gil E, Magnussen H.

BMC Pulm Med. 2014 Dec 23;14:209. doi: 10.1186/1471-2466-14-209.


A randomised, placebo- and active-controlled dose-finding study of aclidinium bromide administered twice a day in COPD patients.

Singh D, Magnussen H, Kirsten A, Mindt S, Caracta C, Seoane B, Jarreta D, Garcia Gil E.

Pulm Pharmacol Ther. 2012 Jun;25(3):248-53. doi: 10.1016/j.pupt.2012.03.008. Epub 2012 Apr 4. Erratum in: Pulm Pharmacol Ther. 2013 Apr;26(2):305.


Aclidinium bromide improves exercise endurance and lung hyperinflation in patients with moderate to severe COPD.

Maltais F, Celli B, Casaburi R, Porszasz J, Jarreta D, Seoane B, Caracta C.

Respir Med. 2011 Apr;105(4):580-7. doi: 10.1016/j.rmed.2010.11.019. Epub 2010 Dec 22.


Peak inspiratory flow through the Genuair inhaler in patients with moderate or severe COPD.

Magnussen H, Watz H, Zimmermann I, Macht S, Greguletz R, Falques M, Jarreta D, Garcia Gil E.

Respir Med. 2009 Dec;103(12):1832-7. doi: 10.1016/j.rmed.2009.07.006. Epub 2009 Aug 3.


Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathy.

Jarreta D, Orús J, Barrientos A, Miró O, Roig E, Heras M, Moraes CT, Cardellach F, Casademont J.

Cardiovasc Res. 2000 Mar;45(4):860-5.


Oxidative damage on lymphocyte membranes is increased in patients suffering from acute carbon monoxide poisoning.

Miró O, Alonso JR, Casademont J, Jarreta D, Urbano-Márquez A, Cardellach F.

Toxicol Lett. 1999 Nov 22;110(3):219-23.


Absence of mitochondrial dysfunction in polymyalgia rheumatica. Evidence based on a simultaneous molecular and biochemical approach.

Miró O, Jarreta D, Casademont J, Barrientos A, Rodríguez B, Gómez M, Nunes V, Urbano-Márquez A, Cardellach F.

Scand J Rheumatol. 1999;28(5):319-23.


Localization and mobility of coenzyme Q in lipid bilayers and membranes.

Lenaz G, Fato R, Di Bernardo S, Jarreta D, Costa A, Genova ML, Parenti Castelli G.

Biofactors. 1999;9(2-4):87-93. Review.


Skeletal muscle mitochondrial function in polymyalgia rheumatica and in giant cell arteritis.

Miró O, Casademont J, Jarreta D, Grau JM, Urbano-Márquez A, Cardellach F.

Rheumatology (Oxford). 1999 Jun;38(6):568-71.


Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes.

Miró O, Alonso JR, Jarreta D, Casademont J, Urbano-Márquez A, Cardellach F.

Carcinogenesis. 1999 Jul;20(7):1331-6.


Effects of general anaesthetic procedures on mitochondrial function of human skeletal muscle.

Miró O, Barrientos A, Alonso JR, Casademont J, Jarreta D, Urbano-Márquez A, Cardellach F.

Eur J Clin Pharmacol. 1999 Mar;55(1):35-41.


Histological and biochemical assessment of mitochondrial function in dermatomyositis.

Miró O, Casademont J, Grau JM, Jarreta D, Urbano-Márquez A, Cardellach F.

Br J Rheumatol. 1998 Oct;37(10):1047-53.


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