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Items: 19


Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment.

Ma J, Huo X, Jarpe MB, Kavelaars A, Heijnen CJ.

Acta Neuropathol Commun. 2018 Oct 1;6(1):103. doi: 10.1186/s40478-018-0604-3.


HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy.

Krukowski K, Ma J, Golonzhka O, Laumet GO, Gutti T, van Duzer JH, Mazitschek R, Jarpe MB, Heijnen CJ, Kavelaars A.

Pain. 2017 Jun;158(6):1126-1137. doi: 10.1097/j.pain.0000000000000893.


Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.

Min C, Moore N, Shearstone JR, Quayle SN, Huang P, van Duzer JH, Jarpe MB, Jones SS, Yang M.

PLoS One. 2017 Jan 6;12(1):e0169128. doi: 10.1371/journal.pone.0169128. eCollection 2017.


Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2.

Shearstone JR, Golonzhka O, Chonkar A, Tamang D, van Duzer JH, Jones SS, Jarpe MB.

PLoS One. 2016 Apr 13;11(4):e0153767. doi: 10.1371/journal.pone.0153767. eCollection 2016.


Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice.

Regna NL, Vieson MD, Luo XM, Chafin CB, Puthiyaveetil AG, Hammond SE, Caudell DL, Jarpe MB, Reilly CM.

Clin Immunol. 2016 Jan;162:58-73. doi: 10.1016/j.clim.2015.11.007. Epub 2015 Nov 22.


Influence of canonical structure determining residues on antibody affinity and stability.

Clark LA, Demarest SJ, Eldredge J, Jarpe MB, Li Y, Simon K, van Vlijmen HW.

J Struct Biol. 2014 Feb;185(2):223-7. doi: 10.1016/j.jsb.2013.08.009. Epub 2013 Aug 29.


Apoptosis stimulated by the 91-kDa caspase cleavage MEKK1 fragment requires translocation to soluble cellular compartments.

Schlesinger TK, Bonvin C, Jarpe MB, Fanger GR, Cardinaux JR, Johnson GL, Widmann C.

J Biol Chem. 2002 Mar 22;277(12):10283-91. Epub 2002 Jan 8.


Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human.

Widmann C, Gibson S, Jarpe MB, Johnson GL.

Physiol Rev. 1999 Jan;79(1):143-80. Review.


Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.

Jarpe MB, Widmann C, Knall C, Schlesinger TK, Gibson S, Yujiri T, Fanger GR, Gelfand EW, Johnson GL.

Oncogene. 1998 Sep 17;17(11 Reviews):1475-82. Review.


MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.

Widmann C, Gerwins P, Johnson NL, Jarpe MB, Johnson GL.

Mol Cell Biol. 1998 Apr;18(4):2416-29.


[D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P acts as a biased agonist toward neuropeptide and chemokine receptors.

Jarpe MB, Knall C, Mitchell FM, Buhl AM, Duzic E, Johnson GL.

J Biol Chem. 1998 Jan 30;273(5):3097-104.


Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha.

Chan ED, Winston BW, Jarpe MB, Wynes MW, Riches DW.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13169-74.


MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

Fanger GR, Gerwins P, Widmann C, Jarpe MB, Johnson GL.

Curr Opin Genet Dev. 1997 Feb;7(1):67-74. Review.


Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death.

Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL.

J Biol Chem. 1996 Feb 9;271(6):3229-37.


Nuclear lipid metabolism in NEST: Nuclear Envelope Signal Transduction.

Raben DM, Jarpe MB, Leach KL.

J Membr Biol. 1994 Oct;142(1):1-7. Review.


Alpha-thrombin stimulates nuclear diglyceride levels and differential nuclear localization of protein kinase C isozymes in IIC9 cells.

Leach KL, Ruff VA, Jarpe MB, Adams LD, Fabbro D, Raben DM.

J Biol Chem. 1992 Oct 25;267(30):21816-22.


Nursing care of patients receiving long-term infusion of neuromuscular blocking agents.

Jarpe MB.

Crit Care Nurse. 1992 Oct;12(7):58-63. No abstract available.


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